Arginase 1 activity worsens lung-protective immunity against Streptococcus pneumoniae infection

European Journal of Immunology

Volumn 45, Issue 6, 2015, Pages 1716-1726

  Knippenberg, Sarah ^a   Brumshagen, Christina ^a   Aschenbrenner, Franziska ^a   Welte, Tobias ^a,b   Maus, Ulrich A ^a,b  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH)   (Germany)

Author keywords

Alternative macrophage activation; Arg1; IL 13; Inflammation; Lung

Indexed keywords

ARGINASE 1; INTERLEUKIN 13; INTERLEUKIN 33; INTERLEUKIN 4; MESSENGER RNA; NITRIC OXIDE; ARG1 PROTEIN, MOUSE; ARGINASE; CYTOKINE;

ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BACTERIAL LOAD; BONE MARROW CELL; COMPARATIVE STUDY; DNA SYNTHESIS; ENZYME ACTIVITY; GENE EXPRESSION; HOST RESISTANCE; IN VITRO STUDY; LUNG ALVEOLUS MACROPHAGE; LUNG INFECTION; LUNG LAVAGE; LUNG RESISTANCE; MOUSE; NONHUMAN; PNEUMOCOCCAL INFECTION; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; STREPTOCOCCUS PNEUMONIAE; TH2 CELL; UPREGULATION; WESTERN BLOTTING; ANIMAL; DISEASE MODEL; ENZYME ACTIVATION; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; STREPTOCOCCUS PNEUMONIA;

ANIMALS; ARGINASE; CYTOKINES; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; GENE EXPRESSION; HOST-PATHOGEN INTERACTIONS; MACROPHAGES, ALVEOLAR; MICE; MICE, KNOCKOUT; MYELOID CELLS; PNEUMONIA, PNEUMOCOCCAL; STREPTOCOCCUS PNEUMONIAE; TH2 CELLS;

EID: 84930413050     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201445419     Document Type: Article

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