Local delivery of GM-CSF protects mice from lethal pneumococcal pneumonia

Journal of Immunology

Volumn 187, Issue 10, 2011, Pages 5346-5356

  Steinwede, Kathrin ^a   Tempelhof, Ole ^a   Bolte, Kristine ^a   Maus, Regina ^a   Bohling, Jennifer ^a   Ueberberg, Bianca ^a   Länger, Florian ^a   Christman, John W ^b   Paton, James C ^c   Ask, Kjetil ^d   Maharaj, Shyam ^d   Kolb, Martin ^d   Gauldie, Jack ^d   Welte, Tobias ^a   Maus, Ulrich A ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c UNIVERSITY OF ADELAIDE   (Australia)

^d MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CASPASE 3; CD11B ANTIGEN; CYTOKINE; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 12; INTERLEUKIN 6; KERATINOCYTE CHEMOATTRACTANT; MACROPHAGE INFLAMMATORY PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 1; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; STAT5 PROTEIN; TOLL LIKE RECEPTOR 2; TRANSCRIPTION FACTOR PU 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; DRUG ADMINISTRATION ROUTE; GENE; GENE EXPRESSION; GENE OVEREXPRESSION; IMMUNOSTIMULATION; INDUCIBLE NITRIC OXIDE SYNTHASE GENE; INNATE IMMUNITY; INTRA ALVEOLAR DELIVERY; LUNG ALVEOLUS; LUNG ALVEOLUS CELL; LUNG ALVEOLUS MACROPHAGE; MORTALITY; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; STREPTOCOCCUS PNEUMONIA; SURVIVAL RATE; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY;

ADENOVIRIDAE; ANIMALS; BRONCHOALVEOLAR LAVAGE FLUID; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; INTUBATION, INTRATRACHEAL; LUNG; MICE; MICE, INBRED C57BL; PNEUMONIA, PNEUMOCOCCAL; RECOMBINANT PROTEINS;

EID: 81455154938     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1101413     Document Type: Article

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