Inducible Gata1 suppression expands megakaryocyteerythroid progenitors from embryonic stem cells

Journal of Clinical Investigation

Volumn 125, Issue 6, 2015, Pages 2369-2374

  Noh, Ji Yoon ^a   Gandre Babbe, Shilpa ^a   Wang, Yuhuan ^a   Hayes, Vincent ^a   Yao, Yu ^a   Gadue, Paul ^a   Sullivan, Spencer K ^a   Chou, Stella T ^a   Machlus, Kellie R ^b   Italiano, Joseph E ^b   Kyba, Michael ^c   Finkelstein, David ^d   Ulirsch, Jacob C ^e   Sankaran, Vijay G ^e   French, Deborah L ^a   Poncz, Mortimer ^a   Weiss, Mitchell J ^d  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^d ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^e DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; DOXYCYCLINE; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR GATA 1; ANTIINFECTIVE AGENT; GATA1 PROTEIN, MOUSE; THROMBOPOIETIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CELL ENGINEERING; CELL MATURATION; CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; ERYTHROBLAST; GENE EXPRESSION REGULATION; GENE REPRESSION; MEGAKARYOCYTE; MEGAKARYOCYTE ERYTHROID PROGENITOR; MEGAKARYOPOIESIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; STEM CELL EXPANSION; THROMBOCYTE FUNCTION; THROMBOCYTE TRANSFUSION; ANIMAL; BIOSYNTHESIS; CYTOLOGY; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM;

ANIMALS; ANTI-BACTERIAL AGENTS; CELL DIFFERENTIATION; DOXYCYCLINE; EMBRYONIC STEM CELLS; GATA1 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION; HUMANS; MEGAKARYOCYTE-ERYTHROID PROGENITOR CELLS; MEGAKARYOCYTES; MICE; THROMBOPOIETIN;

EID: 84930409429     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI77670     Document Type: Article

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