P2RX 7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy

Cell Research

Volumn 25, Issue 6, 2015, Pages 674-690

  Wang, Huan ^a,b   Hong, Ling Juan ^a   Huang, Ji Yun ^a   Jiang, Quan ^a   Tao, Rong Rong ^a   Tan, Chao ^a   Lu, Nan Nan ^a   Wang, Cheng Kun ^a   Ahmed, Muhammad M ^a   Lu, Ying Mei ^c   Liu, Zhi Rong ^d   Shi, Wei Xing ^e   Lai, En Yin ^f   Wilcox, Christopher S ^g   Han, Feng ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b DALIAN UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY CITY COLLEGE   (China)

^d ZHEJIANG UNIVERSITY   (China)

^e LOMA LINDA UNIVERSITY HEALTH   (United States)

^f ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^g GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

ICAM 1; leukocyte adhesion; microglia; neurovascular injury; P2RX7; septic encephalopathy; two photon imaging

Indexed keywords

MUS;

CD11B ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; P2RX7 PROTEIN, MOUSE; PURINERGIC P2X7 RECEPTOR;

ANIMAL; BRAIN INJURY; CELL ADHESION; ENDOTHELIUM CELL; LEUKOCYTE; METABOLISM; MOUSE; MUTANT MOUSE STRAIN; PATHOLOGY; SEPSIS ASSOCIATED ENCEPHALOPATHY;

ANIMALS; BRAIN INJURIES; CELL ADHESION; ENDOTHELIAL CELLS; INTERCELLULAR ADHESION MOLECULE-1; LEUKOCYTES; MACROPHAGE-1 ANTIGEN; MICE; MICE, MUTANT STRAINS; RECEPTORS, PURINERGIC P2X7; SEPSIS-ASSOCIATED ENCEPHALOPATHY;

EID: 84930384613     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2015.61     Document Type: Article

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