In vivo two-photon fluorescence microscopy reveals disturbed cerebral capillary blood flow and increased susceptibility to ischemic insults in diabetic mice

CNS Neuroscience and Therapeutics

Volumn 20, Issue 9, 2014, Pages 816-822

  Huang, Ji Yun ^a   Li, Li Tao ^a,b   Wang, Huan ^a   Liu, Shuang Shuang ^c   Lu, Ying Mei ^d   Liao, Mei Hua ^a   Tao, Rong Rong ^a   Hong, Ling Juan ^a   Fukunaga, Kohji ^e   Chen, Zhong ^f   Wilcox, Christopher S ^g   Lai, En Yin ^c   Han, Feng ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b HEBEI GENERAL HOSPITAL   (China)

^c ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d ZHEJIANG UNIVERSITY CITY COLLEGE   (China)

^e TOHOKU UNIVERSITY   (Japan)

^f ZHEJIANG UNIVERSITY   (China)

^g GEORGETOWN UNIVERSITY   (United States)

Author keywords

Capillary; Cerebral blood flow; Diabetes; Hyperglycemia; Ischemia; Two photon laser scanning microscopy

Indexed keywords

GREEN FLUORESCENT PROTEIN; TIGHT JUNCTION PROTEIN; AMPA RECEPTOR; ANGIOPOIETIN RECEPTOR; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; GLUTAMATE RECEPTOR IONOTROPIC, AMPA 1; TEK PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BLOOD FLOW; BRAIN ARTERY; BRAIN CAPILLARY; BRAIN DAMAGE; BRAIN TISSUE; BRAIN VEIN; CAPILLARY; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; DIABETES MELLITUS; ERYTHROCYTE; FLUORESCENCE MICROSCOPY; IN VIVO STUDY; LASER MICROSCOPY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; ANALYSIS OF VARIANCE; ANIMAL; BLOOD FLOW VELOCITY; BRAIN CIRCULATION; BRAIN CORTEX; CEREBRAL ARTERY DISEASE; DISEASE MODEL; DISEASE PREDISPOSITION; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; GENETICS; LASER DOPPLER FLOWMETRY; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE; VASCULARIZATION;

ANALYSIS OF VARIANCE; ANIMALS; BLOOD FLOW VELOCITY; BLOOD-BRAIN BARRIER; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CEREBRAL CORTEX; CEREBROVASCULAR CIRCULATION; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; DISEASE SUSCEPTIBILITY; ERYTHROCYTES; GREEN FLUORESCENT PROTEINS; INFARCTION, MIDDLE CEREBRAL ARTERY; LASER-DOPPLER FLOWMETRY; MICE; MICE, TRANSGENIC; RECEPTOR, TIE-2; RECEPTORS, AMPA;

EID: 84906260573     PISSN: 17555930     EISSN: 17555949     Source Type: Journal    
DOI: 10.1111/cns.12268     Document Type: Article

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