Microparticles Containing Curcumin Solid Dispersion: Stability, Bioavailability and Anti-Inflammatory Activity

AAPS PharmSciTech

Volumn 17, Issue 2, 2016, Pages 252-261

  Teixeira, C C C ^a   Mendonca L M ^a   Bergamaschi, M M ^a   Queiroz, R H C ^a   Souza, G E P ^a   Antunes, L M G ^a   Freitas, L A P ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

bioavailability; blood level; dissolution; rat paw oedema; solubility; spray drying; thermal analysis; turmeric

Indexed keywords

CURCUMIN; ANTIINFLAMMATORY AGENT; FAT; GELUCIRE 50-13; OIL; SILICON DIOXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CALORIMETRY; COMPARATIVE STUDY; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG STABILITY; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; INFRARED SPECTROSCOPY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PARTICLE SIZE; PAW EDEMA; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; SCALE UP; SCANNING ELECTRON MICROSCOPY; SOLID DISPERSION; SPRAY DRYING; X RAY POWDER DIFFRACTION; ANIMAL; BIOAVAILABILITY; CHEMISTRY; MEDICINAL CHEMISTRY; PHARMACEUTICS; PROCEDURES; SOLUBILITY; WISTAR RAT; X RAY DIFFRACTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; CURCUMIN; DRUG STABILITY; FATS; MALE; OILS; RATS; RATS, WISTAR; SILICON DIOXIDE; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; X-RAY DIFFRACTION;

EID: 84930340065     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-015-0337-6     Document Type: Article

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