Alprazolam dependence prevented by substituting with the β-carboline abecarnil

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 6, 1997, Pages 2719-2723

  Pinna, Graziano ^a,b   Galici, Ruggero ^a,b   Schneider, Herbert H ^a   Stephens, David N ^a,c   Turski, Lechoslaw ^a  

^a BAYER PHARMA AG   (Germany)

^b UNIVERSITY OF CAGLIARI   (Italy)

^c UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

benzodiazepines; replacement therapy; tolerance; withdrawal

Indexed keywords

5 ISOPROPOXY 4 METHYL BETA CARBOLINE 3 CARBOXYLIC ACID ETHYL ESTER; ABECARNIL; ALPRAZOLAM; ANXIOLYTIC AGENT; BENZODIAZEPINE; BENZODIAZEPINE RECEPTOR; BETA CARBOLINE DERIVATIVE;

ANIMAL MODEL; ANXIETY; ARTICLE; CONTROLLED STUDY; DRUG DEPENDENCE; DRUG DEPENDENCE TREATMENT; DRUG TOLERANCE; DRUG WITHDRAWAL; ELECTROENCEPHALOGRAPHY; ELECTROMYOGRAPHY; MALE; MOUSE; MUSCLE RIGIDITY; NONHUMAN; PRIORITY JOURNAL; SEIZURE; SUBCUTANEOUS DRUG ADMINISTRATION;

ALPRAZOLAM; ANALYSIS OF VARIANCE; ANIMALS; ANTICONVULSANTS; ANXIETY; CARBOLINES; ELECTROENCEPHALOGRAPHY; ELECTROMYOGRAPHY; MALE; MICE; MICE, INBRED STRAINS; SUBSTANCE WITHDRAWAL SYNDROME; SUBSTANCE-RELATED DISORDERS; TIME FACTORS;

ANIMALIA;

EID: 0031002912     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.6.2719     Document Type: Article

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