Early onset of cognitive impairment is associated with altered synaptic plasticity and enhanced hippocampal GluA1 expression in a mouse model of depression

Neurobiology of Aging

Volumn 36, Issue 5, 2015, Pages 1938-1952

  Gross, Moshe ^a,b   Sheinin, Anton ^a   Nesher, Elimelech ^b   Tikhonov, Tatiana ^b   Baranes, Danny ^b   Pinhasov, Albert ^b   Michaelevski, Izhak ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b ARIEL UNIVERSITY   (Israel)

Author keywords

AMPAR; Depression; Hippocampus; Long term potentiation; Memory; Submissiveness

Indexed keywords

AMPA RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; SOMATOMEDIN; GLUTAMATE RECEPTOR IONOTROPIC, AMPA 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; BRAIN LEVEL; COGNITIVE DEFECT; CONTROLLED STUDY; DEPRESSION; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; FACILITATION; GENE EXPRESSION; HIPPOCAMPAL CA1 REGION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LONG TERM MEMORY; LONG TERM POTENTIATION; MALE; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; NOVEL OBJECT RECOGNITION TEST; ONSET AGE; OPEN FIELD TEST; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; AGING; ANIMAL; COGNITION; COGNITION DISORDERS; COMPLICATION; DISEASE MODEL; GENETICS; HIPPOCAMPUS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOLOGY;

AGING; ANIMALS; COGNITION; COGNITION DISORDERS; DEPRESSION; DISEASE MODELS, ANIMAL; GENE EXPRESSION; HIPPOCAMPUS; MALE; MICE; NEURONAL PLASTICITY; RECEPTORS, AMPA;

EID: 84930232263     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2015.02.015     Document Type: Article

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