Real-time monitoring of ATP-responsive drug release using mesoporous-silica-coated multicolor upconversion nanoparticles

ACS Nano

Volumn 9, Issue 5, 2015, Pages 5234-5245

  Lai, Jinping ^a   Shah, Birju P ^a   Zhang, Yixiao ^a   Yang, Letao ^a   Lee, Ki Bum ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

core shell nanoparticles; luminescence resonance energy transfer (LRET); real time monitoring; stimuli responsive drug delivery; upconversion nanoparticle

Indexed keywords

ADENOSINETRIPHOSPHATE; BIOINFORMATICS; ENERGY TRANSFER; INFRARED DEVICES; LUMINESCENCE; MEDICAL NANOTECHNOLOGY; MONITORING; SILICA; STEM CELLS; ZINC;

CORE-SHELL NANOPARTICLES; REAL TIME MONITORING; RESONANCE ENERGY TRANSFER; STIMULI-RESPONSIVE DRUG DELIVERIES; UPCONVERSION NANOPARTICLES;

NANOPARTICLES;

2,2'-DIPICOLYLAMINE; ADENOSINE TRIPHOSPHATE; AMINE; DOXORUBICIN; DRUG CARRIER; NANOPARTICLE; OLIGOPEPTIDE; PICOLINIC ACID DERIVATIVE; SILICON DIOXIDE; ZINC;

CHEMISTRY; COLOR; DRUG RELEASE; ENERGY TRANSFER; HUMAN; MCF 7 CELL LINE; METABOLISM; NANOMEDICINE; POROSITY;

ADENOSINE TRIPHOSPHATE; AMINES; COLOR; DOXORUBICIN; DRUG CARRIERS; DRUG LIBERATION; ENERGY TRANSFER; HUMANS; MCF-7 CELLS; NANOMEDICINE; NANOPARTICLES; OLIGOPEPTIDES; PICOLINIC ACIDS; POROSITY; SILICON DIOXIDE; ZINC;

EID: 84930212312     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.5b00641     Document Type: Article

References (66)

1. Mura, S.; Nicolas, J.; Couvreur, P. Stimuli-Responsive Nanocarriers for Drug Delivery Nat. Mater. 2013, 12, 991-1003
2. Kim, C. S.; Duncan, B.; Creran, B.; Rotello, V. M. Triggered Nanoparticles as Therapeutics Nano Today. 2013, 8, 439-447
3. Alarcon, C. D. H.; Pennadam, S.; Alexander, C. Stimuli Responsive Polymers for Biomedical Applications Chem. Soc. Rev. 2005, 34, 276-285
4. Lu, Y.; Sun, W. J.; Gu, Z. Stimuli-Responsive Nanomaterials for Therapeutic Protein Delivery J. Controlled Release 2014, 194, 1-19
5. Bansal, A.; Zhang, Y. Photocontrolled Nanoparticle Delivery Systems for Biomedical Applications Acc. Chem. Res. 2014, 47, 3052-3060
6. Ge, Z. S.; Liu, S. Y. Functional Block Copolymer Assemblies Responsive to Tumor and Intracellular Microenvironments for Site-Specific Drug Delivery and Enhanced Imaging Performance Chem. Soc. Rev. 2013, 42, 7289-7325
7. Ta, T.; Porter, T. M. Thermosensitive Liposomes for Localized Delivery and Triggered Release of Chemotherapy J. Controlled Release 2013, 169, 112-125
8. Hu, J. M.; Zhang, G. Q.; Liu, S. Y. Enzyme-Responsive Polymeric Assemblies, Nanoparticles and Hydrogels Chem. Soc. Rev. 2012, 41, 5933-5949
9. Fleige, E.; Quadir, M. A.; Haag, R. Stimuli-Responsive Polymeric Nanocarriers for the Controlled Transport of Active Compounds: Concepts and Applications Adv. Drug Delivery Rev. 2012, 64, 866-884
10. Chen, K. J.; Liang, H. F.; Chen, H. L.; Wang, Y. C.; Cheng, P. Y.; Liu, H. L.; Xia, Y. N.; Sung, H. W. A Thermoresponsive Bubble-Generating Liposomal System for Triggering Localized Extracellular Drug Delivery ACS Nano 2013, 7, 438-446
11. Li, Z. X.; Barnes, J. C.; Bosoy, A.; Stoddart, J. F.; Zink, J. I. Mesoporous Silica Nanoparticles in Biomedical Applications Chem. Soc. Rev. 2012, 41, 2590-2605
12. Vivero-Escoto, J. L.; Huxford-Phillips, R. C.; Lin, W. B. Silica-Based Nanoprobes for Biomedical Imaging and Theranostic Applications Chem. Soc. Rev. 2012, 41, 2673-2685
13. Yang, P. P.; Gai, S. L.; Lin, J. Functionalized Mesoporous Silica Materials for Controlled Drug Delivery Chem. Soc. Rev. 2012, 41, 3679-3698
14. Popat, A.; Hartono, S. B.; Stahr, F.; Liu, J.; Qiao, S. Z.; Lu, G. Q. Mesoporous Silica Nanoparticles for Bioadsorption, Enzyme Immobilisation, and Delivery Carriers Nanoscale 2011, 3, 2801-2818
15. Wang, Y.; Wang, K. Y.; Zhang, R.; Liu, X. G.; Yan, X. Y.; Wang, J. X.; Wagner, E.; Huang, R. Q. Synthesis of Core-Shell Graphitic Carbon@Silica Nanospheres with Dual-Ordered Mesopores for Cancer-Targeted Photothermochemotherapy ACS Nano 2014, 8, 7870-7879
16. Xiao, D.; Jia, H. Z.; Zhang, J.; Liu, C. W.; Zhuo, R. X.; Zhang, X. Z. A Dual-Responsive Mesoporous Silica Nanoparticle for Tumor-Triggered Targeting Drug Delivery Small 2014, 10, 591-598
17. Lai, J. P.; Shah, B. P.; Garfunkel, E.; Lee, K. B. Versatile Fluorescence Resonance Energy Transfer-Based Mesoporous Silica Nanoparticles for Real-Time Monitoring of Drug Release ACS Nano 2013, 7, 2741-2750
18. Chen, X.; Soeriyadi, A. H.; Lu, X.; Sagnella, S. M.; Kavallaris, M.; Gooding, J. J. Dual Bioresponsive Mesoporous Silica Nanocarrier as an "and" Logic Gate for Targeted Drug Delivery Cancer Cells Adv. Funct. Mater. 2014, 24, 6999-7006
19. Chen, Y. W.; Chen, P. J.; Hu, S. H.; Chen, I. W.; Chen, S. Y. NIR-Triggered Synergic Photo-Chemothermal Therapy Delivered by Reduced Graphene Oxide/Carbon/Mesoporous Silica Nanocookies Adv. Funct. Mater. 2014, 24, 451-459
20. Jayakumar, M. K. G.; Idris, N. M.; Zhang, Y. Remote Activation of Biomolecules in Deep Tissues Using Near-Infrared-to-UV Upconversion Nanotransducers Proc. Natl. Acad. Sci. U. S. A. 2012, 109, 8483-8488
21. Lai, J. P.; Mu, X.; Xu, Y. Y.; Wu, X. L.; Wu, C. L.; Li, C.; Chen, J. B.; Zhao, Y. B. Light-Responsive Nanogated Ensemble Based on Polymer Grafted Mesoporous Silica Hybrid Nanoparticles Chem. Commun. 2010, 46, 7370-7372
22. Safari, J.; Zarnegar, Z. Advanced Drug Delivery Systems: Nanotechnology of Health Design a Review J. Saudi Chem. Soc. 2014, 18, 85-99
23. Zhang, Z. X.; Balogh, D.; Wang, F. A.; Sung, S. Y.; Nechushtai, R.; Willner, I. Biocatalytic Release of an Anticancer Drug from Nucleic-Acids-Capped Mesoporous SiO2 Using DNA or Molecular Biomarkers as Triggering Stimuli ACS Nano 2013, 7, 8455-8468
24. De la Torre, C.; Mondragon, L.; Coll, C.; Sancenon, F.; Marcos, M. D.; Martinez-Manez, R.; Amoros, P.; Perez-Paya, E.; Orzaez, M. Cathepsin-B Induced Controlled Release from Peptide-Capped Mesoporous Silica Nanoparticles Chem.-Eur. J. 2014, 20, 15309-15314
25. Villalonga, R.; Diez, P.; Sanchez, A.; Aznar, E.; Martinez-Manez, R.; Pingarron, J. M. Enzyme-Controlled Sensing-Actuating Nanomachine Based on Janus Au-Mesoporous Silica Nanoparticles Chem.-Eur. J. 2013, 19, 7889-7894
26. Li, L. L.; Wang, H. Enzyme-Coated Mesoporous Silica Nanoparticles as Efficient Antibacterial Agents in Vivo Adv. Healthcare Mater. 2013, 2, 1351-1360
27. Chen, Z. W.; Li, Z. H.; Lin, Y. H.; Yin, M. L.; Ren, J. S.; Qu, X. G. Bioresponsive Hyaluronic Acid-Capped Mesoporous Silica Nanoparticles for Targeted Drug Delivery Chem.-Eur. J. 2013, 19, 1778-1783
28. Popat, A.; Ross, B. P.; Liu, J.; Jambhrunkar, S.; Kleitz, F.; Qiao, S. Z. Enzyme-Responsive Controlled Release of Covalently Bound Prodrug from Functional Mesoporous Silica Nanospheres Angew. Chem., Int. Ed. 2012, 51, 12486-12489
29. Zhou, Y. F.; Tozzi, F.; Chen, J. Y.; Fan, F.; Xia, L.; Wang, J. R.; Gao, G.; Zhang, A. J.; Xia, X. F.; Brasher, H. et al. Intracellular ATP Levels are a Pivotal Determinant of Chemoresistance in Colon Cancer Cells Cancer Res. 2012, 72, 304-314
30. Beis, I.; Newsholme, E. A. The Contents of Adenine Nucleotides, Phosphagens and Some Glycolytic Intermediates in Resting Muscles from Vertebrates and Invertebrates Biochem. J. 1975, 152, 23-32
31. Sperlagh, B.; Vizi, E. S. Neuronal Synthesis, Storage and Release of ATP Semin. Neurosci. 1996, 8, 175-186
32. He, X. X.; Zhao, Y. X.; He, D. G.; Wang, K. M.; Xu, F. Z.; Tang, J. L. ATP-Responsive Controlled Release System Using Aptamer-Functionalized Mesoporous Silica Nanoparticles Langmuir 2012, 28, 12909-12915
33. Mo, R.; Jiang, T. Y.; DiSanto, R.; Tai, W. Y.; Gu, Z. ATP-Triggered Anticancer Drug Delivery Nat. Commun. 2014, 5, 3364
34. Mo, R.; Jiang, T. Y.; Gu, Z. Enhanced Anticancer Efficacy by ATP-Mediated Liposomal Drug Delivery Angew. Chem., Int. Ed. 2014, 53, 5815-5820
35. Myhr, G. Multimodal Cancer Treatment: Real Time Monitoring, Optimization, and Synergistic Effects Technol. Cancer Res. Treat. 2008, 7, 409-414
36. Probst, C. E.; Zrazhevskiy, P.; Bagalkot, V.; Gao, X. H. Quantum Dots as a Platform for Nanoparticle Drug Delivery Vehicle Design Adv. Drug Delivery Rev. 2013, 65, 703-718
37. Panikkanvalappil, S. R.; Mahmoud, M. A.; Mackey, M. A.; El-Sayed, M. A. Surface-Enhanced Raman Spectroscopy for Real-Time Monitoring of Reactive Oxygen Species-Induced DNA Damage and Its Prevention by Platinum Nanoparticles ACS Nano 2013, 7, 7524-7533
38. Ock, K.; Jeon, W. I.; Ganbold, E. O.; Kim, M.; Park, J.; Seo, J. H.; Cho, K.; Joo, S. W.; Lee, S. Y. Real-Time Monitoring of Glutathione-Triggered Thiopurine Anticancer Drug Release in Live Cells Investigated by Surface-Enhanced Raman Scattering Anal. Chem. 2012, 84, 2172-2178
39. Fernando, R.; Downs, J.; Maples, D.; Ranjan, A. MRI-Guided Monitoring of Thermal Dose and Targeted Drug Delivery for Cancer Therapy Pharm. Res. 2013, 30, 2709-2717
40. Liu, J. N.; Bu, W. B.; Pan, L. M.; Zhang, S.; Chen, F.; Zhou, L. P.; Zhao, K. L.; Peng, W. J.; Shi, J. L. Simultaneous Nuclear Imaging and Intranuclear Drug Delivery by Nuclear-Targeted Multifunctional Upconversion Nanoprobes Biomaterials. 2012, 33, 7282-7290
41. Liu, J. N.; Bu, J. W.; Bu, W. B.; Zhang, S. J.; Pan, L. M.; Fan, W. P.; Chen, F.; Zhou, L. P.; Peng, W. J.; Zhao, K. L. et al. Real-Time in Vivo Quantitative Monitoring of Drug Release by Dual-Mode Magnetic Resonance and Upconverted Luminescence Imaging Angew. Chem., Int. Ed. 2014, 53, 4551-4555
42. Saeed, M.; Saloner, D.; Weber, O.; Martin, A.; Henk, C.; Higgins, C. MRI in Guiding and Assessing Intramyocardial Therapy Eur. Radiol. 2005, 15, 851-863
43. Tagami, T.; Foltz, W. D.; Ernsting, M. J.; Lee, C. M.; Tannock, I. F.; May, J. P.; Li, S. D. MRI Monitoring of Intratumoral Drug Delivery and Prediction of the Therapeutic Effect with a Multifunctional Thermosensitive Liposome Biomaterials 2011, 32, 6570-6578
44. Jana, A.; Nguyen, K. T.; Li, X.; Zhu, P. C.; Tan, N. S.; Agren, H.; Zhao, Y. L. Perylene-Derived Single-Component Organic Nanoparticles with Tunable Emission: Efficient Anticancer Drug Carriers with Real-Time Monitoring of Drug Release ACS Nano 2014, 8, 5939-5952
45. Qiu, F.; Wang, D. L.; Zhu, Q.; Zhu, L. J.; Tong, G. S.; Lu, Y. F.; Yan, D. Y.; Zhu, X. Y. Real-Time Monitoring of Anticancer Drug Release with Highly Fluorescent Star-Conjugated Copolymer as a Drug Carrier Biomacromolecules 2014, 15, 1355-1364
46. Gui, R. J.; Wan, A. J.; Zhang, Y. L.; Li, H. L.; Zhao, T. T. Ratiometric and Time-Resolved Fluorimetry from Quantum Dots Featuring Drug Carriers for Real-Time Monitoring of Drug Release in Situ Anal. Chem. 2014, 86, 5211-5214
47. Tang, J.; Kong, B.; Wu, H.; Xu, M.; Wang, Y. C.; Wang, Y. L.; Zhao, D. Y.; Zheng, G. F. Carbon Nanodots Featuring Efficient FRET for Real-Time Monitoring of Drug Delivery and Two-Photon Imaging Adv. Mater. 2013, 25, 6569-6574
48. Yang, Y. M. Upconversion Nanophosphors for Use in Bioimaging, Therapy, Drug Delivery and Bioassays Microchim. Acta 2014, 181, 263-294
49. Nguyen, P. D.; Son, S. J.; Min, J. Upconversion Nanoparticles in Bioassays, Optical Imaging and Therapy J. Nanosci. Nanotechnol. 2014, 14, 157-174
50. Chen, F.; Bu, W.; Cai, W.; Shi, J. Functionalized Upconversion Nanoparticles: Versatile Nanoplatforms for Translational Research Curr. Mol. Med. 2013, 13, 1613-1632
51. Lai, J. P.; Zhang, Y. X.; Pasquale, N.; Lee, K. B. An Upconversion Nanoparticle with Orthogonal Emissions Using Dual NIR Excitations for Controlled Two-Way Photoswitching Angew. Chem., Int. Ed. 2014, 53, 14419-14423
52. Chen, G. Y.; Qju, H. L.; Prasad, P. N.; Chen, X. Y. Upconversion Nanoparticles: Design, Nanochemistry, and Applications in Theranostics Chem. Rev. 2014, 114, 5161-5214
53. Hirayama, T.; Taki, M.; Kodan, A.; Kato, H.; Yamamoto, Y. Selective Labeling of Tag-Fused Protein by Tryptophan-Sensitized Luminescence of a Terbium Complex Chem. Commun. 2009, 3196-3198
54. Ojida, A.; Honda, K.; Shinmi, D.; Kiyonaka, S.; Mori, Y.; Hamachi, I. Oligo-Asp Tag/Zn(II) Complex Probe as a New Pair for Labeling and Fluorescence Imaging of Proteins J. Am. Chem. Soc. 2006, 128, 10452-10459
55. Nonaka, H.; Fujishima, S.; Uchinomiya, S.; Ojida, A.; Hamachi, I. Selective Covalent Labeling of Tag-Fused GPCR Proteins on Live Cell Surface with a Synthetic Probe for Their Functional Analysis J. Am. Chem. Soc. 2010, 132, 9301-9309
56. Jiang, S.; Zhang, Y. Upconversion Nanoparticle-Based FRET System for Study of siRNA in Live Cells Langmuir 2010, 26, 6689-6694
57. Li, Z. Q.; Zhang, Y.; Jiang, S. Multicolor Core/Shell-Structured Upconversion Fluorescent Nanoparticles Adv. Mater. 2008, 20, 4765-4769
58. Gorris, H. H.; Ali, R.; Saleh, S. M.; Wolfbeis, O. S. Tuning the Dual Emission of Photon-Upconverting Nanoparticles for Ratiometric Multiplexed Encoding Adv. Mater. 2011, 23, 1652-1655
59. Ojida, A.; Takashima, I.; Kohira, T.; Nonaka, H.; Hamachi, I. Turn-on Fluorescence Sensing of Nucleoside Polyphosphates Using a Xanthene-Based Zn(II) Complex Chemosensor J. Am. Chem. Soc. 2008, 130, 12095-12101
60. Ojida, A.; Nonaka, H.; Miyahara, Y.; Tamaru, S. I.; Sada, K.; Hamachi, I. Bis(Dpa-Zn-II) Appended Xanthone: Excitation Ratiometric Chemosensor for Phosphate Anions Angew. Chem., Int. Ed. 2006, 45, 5518-5521
61. Boyer, J. C.; Carling, C. J.; Gates, B. D.; Branda, N. R. Two-Way Photoswitching Using One Type of Near-Infrared Light, Upconverting Nanoparticles, and Changing Only the Light Intensity J. Am. Chem. Soc. 2010, 132, 15766-15772
62. Ojida, A.; Fujishima, S.; Honda, K.; Nonaka, H.; Uchinomiya, S.; Hamachi, I. Binuclear Ni-II-DpaTyr Complex as a High Affinity Probe for an Oligo-Aspartate Tag Tethered to Proteins Chem.-Asian J. 2010, 5, 877-886
63. Kricheldorf, H. R. Polypeptides and 100 Years of Chemistry of α-Amino Acid N -Carboxyanhydrides Angew. Chem., Int. Ed. 2006, 45, 5752-5784
64. Wilder, R.; Mobashery, S. The Use of Triphosgene in Preparation of N -Carboxy-α-Amino Acid Anhydrides J. Org. Chem. 1992, 57, 2755-2756
65. Klok, H. A.; Rodriguez-Hernandez, J. Dendritic-Graft Polypeptides Macromolecules 2002, 35, 8718-8723
66. Feng, D.; Song, Y. C.; Shi, W.; Li, X. H.; Ma, H. M. Distinguishing Folate-Receptor-Positive Cells from Folate-Receptor-Negative Cells Using a Fluorescence Off-On Nanoprobe Anal. Chem. 2013, 85, 6530-653