MRI-guided monitoring of thermal dose and targeted drug delivery for cancer Therapy

Pharmaceutical Research

Volumn 30, Issue 11, 2013, Pages 2709-2717

  Fernando, Ruchika ^a   Downs, Jon ^a   Maples, Danny ^a   Ranjan, Ashish ^a  

^a OKLAHOMA STATE UNIVERSITY   (United States)

Author keywords

HIFU; Laser; MRI thermal mapping; nanoparticles; Targeted drug delivery

Indexed keywords

ANTINEOPLASTIC AGENT; CARBON NANOTUBE; DOXORUBICIN; DYE; GADOLINIUM; GOLD NANOPARTICLE; HOLLOW GOLD NANOSPHERE; LIPOSOME; NANOCAGE; NANOCARRIER; NANOROD; NANOSHELL; NANOSPHERE; PACLITAXEL; POLYGLACTIN; UNCLASSIFIED DRUG;

ABLATION THERAPY; ANTINEOPLASTIC ACTIVITY; CANCER CHEMOTHERAPY; CANCER THERAPY; CARBON DIOXIDE LASER; CHROMATOPHORE; CORE TEMPERATURE; DIFFUSION WEIGHTED IMAGING; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG PENETRATION; DRUG RELEASE; DRUG TRANSPORT; DRUG TUMOR LEVEL; HIGH INTENSITY FOCUSED ULTRASOUND; HUMAN; HYDROPHILICITY; HYPERTHERMIC THERAPY; INTERMETHOD COMPARISON; LASER BASED ABLATIVE THERAPY; LIGHT ABSORPTION; LIPOSOMAL DELIVERY; LOW LEVEL LASER THERAPY; MICROWAVE RADIATION; NEODYMIUM YAG LASER; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING GUIDED DRUG DELIVERY; PATIENT INFORMATION; PERSONALIZED MEDICINE; PRIORITY JOURNAL; PROTON RESONANCE FREQUENCY SHIFT THERMOMETRY; REVIEW; SOLID TUMOR; TEMPERATURE DEPENDENCE; TEMPERATURE MEASUREMENT; TEMPERATURE SENSITIVE LIPOSOME DRUG DELIVERY; THERMAL EXPOSURE; THERMOMETRY; THERMOREGULATION; TISSUE THERMAL DOSE MONITORING; TUMOR BLOOD FLOW; TUMOR LOCALIZATION; TUMOR VASCULARIZATION; UNSPECIFIED SIDE EFFECT;

ANIMALS; ANTINEOPLASTIC AGENTS; DRUG DELIVERY SYSTEMS; HUMANS; HYPERTHERMIA, INDUCED; MAGNETIC RESONANCE IMAGING; NEOPLASMS;

EID: 84886098704     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-013-1110-8     Document Type: Review

References (89)

1. C. Sturesson, Lund A. Theoretical modeling of the temperature distribution in laser-induced hyperthermia. Lund Reports on Atomic Physics (LRAP-159).1994.
2. van der Zee J, González D, van Rhoon GC, van Dijk JDP, van Putten WLJ, Hart AAM. Comparison of radiotherapy alone with radiotherapy plus hyperthermia in locally advanced pelvic tumours: a prospective, randomised, multicentre trial. Lancet. 2000;355:1119-25.
3. Kitamura K, Kuwano H, Watanabe M, Nozoe T, Yasuda M, Sumiyoshi K, et al. Prospective randomized study of hyperthermia combined with chemoradiotherapy for esophageal carcinoma. J Surg Oncol. 1995;60:55-8.
4. Napoli A, Anzidei M, Ciolina F, Marotta E, Cavallo Marincola B, Brachetti G, et al. MR-guided high-intensity focused ultrasound: current status of an emerging technology. Cardiovasc Interv Radiol. 2013.
5. Oto A, Sethi I, Karczmar G, McNichols R, Ivancevic MK, Stadler WM, et al. MR imaging-guided focal laser ablation for prostate cancer: phase I trial. Radiology. 2013.
6. Shah DR, Green S, Elliot A, McGahan JP, Khatri VP. Current oncologic applications of radiofrequency ablation therapies. World J Gastrointest Oncol. 2013;5:71-80.
7. Swan RZ, Sindram D, Martinie JB, Iannitti DA. Operative microwave ablation for hepatocellular carcinoma: complications, recurrence, and long-term outcomes. J Gastrointest Surg. 2013;17:719-29.
8. Staruch RM, Ganguly M, Tannock IF, Hynynen K, Chopra R. Enhanced drug delivery in rabbit VX2 tumours using thermosensitive liposomes and MRI-controlled focused ultrasound hyperthermia. Int J Hyperther. 2012;28:776-87.
9. Partanen A, Yarmolenko PS, Viitala A, Appanaboyina S, Haemmerich D, Ranjan A, et al. Mild hyperthermia with magnetic resonance-guided high-intensity focused ultrasound for applications in drug delivery. Int J Hyperth. 2012;28:320-36.
10. de Smet M, Heijman E, Langereis S, Hijnen NM, Grull H. Magnetic resonance imaging of high intensity focused ultrasound mediated drug delivery from temperature-sensitive liposomes: an in vivo proof-of-concept study. J Control Release. 2011;150:102-10.
11. Tandonand P, Farahani K. NCI image-guided drug delivery summit. Cancer Res. 2011;71:314-7.
12. Hynynen K. MRIgHIFU: a tool for image-guided therapeutics. J Magn Reson Imaging. 2011;34:482-93.
13. Lammers T, Rizzo LY, Storm G, Kiessling F. Personalized nanomedicine. Clin Cancer Res. 2012;18:4889-94.
14. Grülland H, Langereis S. Hyperthermia-triggered drug delivery from temperature-sensitive liposomes using MRI-guided high intensity focused ultrasound. J Control Release. 2012;161:317-27.
15. Leach MO. Breast cancer screening in women at high risk using MRI. NMR Biomed. 2009;22:17-27.
16. Quesson B, de Zwart JA, Moonen CTW. Magnetic resonance temperature imaging for guidance of thermotherapy. J Magn Reson Imaging. 2000;12:525-33.
17. Riekeand V, Butts Pauly K. MR thermometry. J Magn Reson Imaging. 2008;27:376-90.
18. Viglianti BL, Abraham SA, Michelich CR, Yarmolenko PS, MacFall JR, Bally MB, et al. In vivo monitoring of tissue pharmacokinetics of liposome/drug using MRI: illustration of targeted delivery. Magn Reson Med. 2004;51:1153-62.
19. Kopelman R, Lee Koo YE, Philbert M, Moffat BA, Ramachandra Reddy G, McConville P, et al. Multifunctional nanoparticle platforms for in vivo MRI enhancement and photodynamic therapy of a rat brain cancer. J Magn Magn Mater. 2005;293:404-10.
20. Chenevert TL, Stegman LD, Taylor JM, Robertson PL, Greenberg HS, Rehemtulla A, et al. Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors. J Natl Cancer Inst. 2000;92:2029-36.
21. Salomir R, Vimeux FC, de Zwart JA, Grenier N, Moonen CT. Hyperthermia by MR-guided focused ultrasound: accurate temperature control based on fast MRI and a physical model of local energy deposition and heat conduction. Magn Reson Med. 2000;43:342-7.
22. de Zwart JA, Vimeux FC, Delalande C, Canioni P, Moonen CT. Fast lipid-suppressed MR temperature mapping with echo-shifted gradient-echo imaging and spectral-spatial excitation. Magn Reson Med. 1999;42:53-9.
23. de Senneville BD, Mougenot C, Moonen CT. Real-time adaptive methods for treatment of mobile organs by MRI-controlled high-intensity focused ultrasound. Magn Reson Med. 2007;57:319-30.
24. Chen L, Rivens I, Ter Haar G, Riddler S, Hill CR, Bensted JPM. Histological changes in rat liver tumours treated with high-intensity focused ultrasound. Ultrasound Med Biol. 1993;19:67-74.
25. Hynynen K, Roemer R, Anhalt D, Johnson C, Xu ZX, Swindell W, et al. A scanned, focused, multiple transducer ultrasonic system for localized hyperthermia treatments. Int J Hyperth. 1987;3:21-35.
26. Hynynen K, Freund WR, Cline HE, Chung AH, Watkins RD, Vetro JP, et al. A clinical, noninvasive, MR imaging-monitored ultrasound surgery method. Radiographics. 1996;16:185-95.
27. Lin WL, Chen YY, Lin SY, Yen JY, Shieh MJ, Kuo TS. Optimal configuration of multiple-focused ultrasound transducers for external hyperthermia. Med Phys. 1999;26:2007.
28. Ebbini ES, Cain CA. Multiple-focus ultrasound phased-array pattern synthesis: optimal driving-signal distributions for hyperthermia. IEEE Trans Ultrason Ferroelectr Freq Control. 1989;36:540-8.
29. Fanand X, Hynynen K. Control of the necrosed tissue volume during noninvasive ultrasound surgery using a 16-element phased array. Med Phys. 1995;22:297.
30. Fanand X, Hynynen K. Ultrasound surgery using multiple sonications - treatment time considerations. Ultrasound Med Biol. 1996;22:471-82.
31. Daum DR, Hynynen K. Thermal dose optimization via temporal switching in ultrasound surgery. IEEE Trans Ultrason Ferroelectr Freq Control. 1998;45:208-15.
32. Daum DR, Hynynen K. A 256-element ultrasonic phased array system for the treatment of large volumes of deep seated tissue. IEEE Trans Ultrason Ferroelectr Freq Control. 1999;46:1254-68.
33. Köhler MO, Mougenot C, Quesson B, Enholm J, Le Bail B, Laurent C, et al. Volumetric HIFU ablation under 3D guidance of rapid MRI thermometry. Med Phys. 2009;36:3521.
34. Ranjan A, Jacobs GC, Woods DL, Negussie AH, Partanen A, Yarmolenko PS, et al. Image-guided drug delivery with magnetic resonance guided high intensity focused ultrasound and temperature sensitive liposomes in a rabbit Vx2 tumor model. J Control Release. 2012;158:487-94.
35. Staruch R, Chopra R, Hynynen K. Hyperthermia in bone generated with MR imaging-controlled focused ultrasound: control strategies and drug delivery. Radiology. 2012;263:117-27.
36. de Smet M, Hijnen NM, Langereis S, Elevelt A, Heijman E, Dubois L, et al. Magnetic resonance guided high-intensity focused ultrasound mediated hyperthermia improves the intratumoral distribution of temperature-sensitive liposomal doxorubicin. Investig Radiol. 2013;48:395-405.
37. Negussie AH, Yarmolenko PS, Partanen A, Ranjan A, Jacobs G, Woods D, et al. Formulation and characterisation of magnetic resonance imageable thermally sensitive liposomes for use with magnetic resonance-guided high intensity focused ultrasound. Int J Hyperth. 2011;27:140-55.
38. Bangham AD, Standish MM, Weissmann G. The action of steroids and streptolysin S on the permeability of phospholipid structures to cations. J Mol Biol. 1965;13:253-9.
39. Koningand GA, Krijger GC. Targeted multifunctional lipid-based nanocarriers for image-guided drug delivery. Anti Cancer Agents Med Chem. 2007;7:425-40.
40. Yatvin MB, Weinstein JN, Dennis WH, Blumenthal R. Design of liposomes for enhanced local release of drugs by hyperthermia. Science (New York, NY). 1978;202:1290-3.
41. Weinstein JN, Magin RL, Yatvin MB, Zaharko DS. Liposomes and local hyperthermia: selective delivery of methotrexate to heated tumors. Science. 1979;204:188-91.
42. Evansand E, Needham D. Physical properties of surfactant bilayer membranes: thermal transitions, elasticity, rigidity, cohesion and colloidal interactions. J Phys Chem. 1987;91:4219-28.
43. Anyarambhatlaand GR, Needham D. Enhancement of the phase transition permeability of DPPC liposomes by incorporation of MPPC: a new temperature-sensitive liposome for use with mild hyperthermia. J Liposome Res. 1999;9:491-506.
44. Leidy C, Wolkers WF, Jørgensen K, Mouritsen OG, Crowe JH. Lateral organization and domain formation in a two-component lipid membrane system. Biophys J. 2001;80:1819-28.
45. Veatch SL, Keller SL. Seeing spots: complex phase behavior in simple membranes. Biochim Biophys Acta (BBA) - Mol Cell Res. 2005;1746:172-85.
46. Kong G, Anyarambhatla G, Petros WP, Braun RD, Colvin OM, Needham D, et al. Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release. Cancer Res. 2000;60:6950-7.
47. Viglianti BL, Ponce AM, Michelich CR, Yu D, Abraham SA, Sanders L, et al. Chemodosimetry of in vivo tumor liposomal drug concentration using MRI. Magn Reson Med. 2006;56:1011-8.
48. Needham D, Anyarambhatla G, Kong G, Dewhirst MW. A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model. Cancer Res. 2000;60:1197-201.
49. Lindner LH, Eichhorn ME, Eibl H, Teichert N, Schmitt-Sody M, Issels RD, et al. Novel temperature-sensitive liposomes with prolonged circulation time. Clin Cancer Res. 2004;10:2168-78.
50. Ponce AM, Viglianti BL, Yu D, Yarmolenko PS, Michelich CR, Woo J, et al. Magnetic resonance imaging of temperature-sensitive liposome release: drug dose painting and antitumor effects. J Natl Cancer Inst. 2007;99:53-63.
51. Dromi S, Frenkel V, Luk A, Traughber B, Angstadt M, Bur M, et al. Pulsed-high intensity focused ultrasound and low temperature-sensitive liposomes for enhanced targeted drug delivery and antitumor effect. Clin Cancer Res. 2007;13:2722-7.
52. Frenkel V, Etherington A, Greene M, Quijano J, Xie J, Hunter F, et al. Delivery of liposomal doxorubicin (Doxil) in a breast cancer tumor model: investigation of potential enhancement by pulsed-high intensity focused ultrasound exposure. Acad Radiol. 2006;13:469-79.
53. Staruch R, Chopra R, Hynynen K. Localised drug release using MRI-controlled focused ultrasound hyperthermia. Int J Hyperth. 2010;27:156-71.
54. Vaupel P, Horsman MR. Tumour perfusion and associated physiology: characterization and significance for hyperthermia. Int J Hyperth. 2010;26:209-10.
55. Sen A, Capitano ML, Spernyak JA, Schueckler JT, Thomas S, Singh AK, et al. Mild elevation of body temperature reduces tumor interstitial fluid pressure and hypoxia and enhances efficacy of radiotherapy in murine tumor models. Cancer Res. 2011;71:3872-80.
56. Manzoor AA, Lindner LH, Landon CD, Park JY, Simnick AJ, Dreher MR, et al. Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors. Cancer Res. 2012;72:5566-75.
57. Dings RP, Loren ML, Zhang Y, Mikkelson S, Mayo KH, Corry P, et al. Tumour thermotolerance, a physiological phenomenon involving vessel normalisation. Int J Hyperth. 2011;27:42-52.
58. Salomir R, Palussière J, Fossheim SL, Rogstad A, Wiggen UN, Grenier N, et al. Local delivery of magnetic resonance (MR) contrast agent in kidney using thermosensitive liposomes and MR imaging-guided local hyperthermia: a feasibility study in vivo. J Magn Reson Imaging. 2005;22:534-40.
59. Lindner L, Reinl H, Schlemmer M, Stahl R, Peller M. Paramagnetic thermosensitive liposomes for MR-thermometry. Int J Hyperth. 2005;21:575-88.
60. Hijnen NM, Heijman E, Köhler MO, Ylihautala M, Ehnholm GJ, Simonetti AW, et al. Tumour hyperthermia and ablation in rats using a clinical MR-HIFU system equipped with a dedicated small animal set-up. Int J Hyperth. 2012;28:141-55.
61. Tagami T, Foltz WD, Ernsting MJ, Lee CM, Tannock IF, May JP, et al. MRI monitoring of intratumoral drug delivery and prediction of the therapeutic effect with a multifunctional thermosensitive liposome. Biomaterials. 2011;32:6570-8.
62. N. Kapanyand N. Peppers. Retinal photocoagulatlon by lasers. 1963.
63. Minton JP, Carlton DM, Dearman JR, McKnight WB, Ketcham AS. An evaluation of the physical response of malignant tumor implants to pulsed laser radiation. Surg Gynaecol Obstet. 1965;121:538-44.
64. Ketcham AS, Hoye RC, Riggle GC. The laser in cancer research. Ann N Y Acad Sci. 1969;168:634-41.
65. Bown S. Phototherapy of tumors. World J Surg. 1983;7:700-9.
66. Steger A, Lees W, Walmsley K, Bown S. Interstitial laser hyperthermia: a new approach to local destruction of tumours. Br Med J. 1989;299:362-5.
67. Mastersand A, Bown S. Interstitial laser hyperthermia in tumour therapy. Ann Chir Gynaecol. 1990;79:244.
68. Vogl TJ, Naguib NNN, Lehnert T, Nour-Eldin NEA. Radiofrequency, microwave and laser ablation of pulmonary neoplasms: clinical studies and technical considerations - review article. Eur J Radiol. 2011;77:346-57.
69. Fuentes D, Walker C, Elliott A, Shetty A, Hazle JD, Stafford RJ. Magnetic resonance temperature imaging validation of a bioheat transfer model for laser-induced thermal therapy. Int J Hyperth. 2011;27:453-64.
70. Andersonand RR, Parrish JA. Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation. Science. 1983;220:524-7.
71. Parrish JA, Anderson RR, Harrist T, Paul B, Murphy GF. Selective thermal effects with pulsed irradiation from lasers: from organ to organelle. J Investig Dermatol. 1983;80:75s-80.
72. Welch A. The thermal response of laser irradiated tissue. IEEE J Quantum Electron. 1984;20:1471-81.
73. Joriand G, Spikes JD. Photothermal sensitizers: possible use in tumor therapy. J Photochem Photobiol B Biol. 1990;6:93-101.
74. Camerin M, Rello S, Villanueva A, Ping X, Kenney ME, Rodgers MAJ, et al. Photothermal sensitisation as a novel therapeutic approach for tumours: studies at the cellular and animal level. Eur J Cancer. 2005;41:1203-12.
75. Huang X, Jain PK, El-Sayed IH, El-Sayed MA. Plasmonic photothermal therapy (PPTT) using gold nanoparticles. Lasers Med Sci. 2008;23:217-28.
76. Rox Anderson R, Parrish JA. Microvasculature can be selectively damaged using dye lasers: a basic theory and experimental evidence in human skin. Lasers Surg Med. 2005;1:263-76.
77. Polla LL, Margolis RJ, Dover JS, Whitaker D, Murphy GF, Jacques SL, et al. Melanosomes are a primary target of Q-switch ruby laser irradiation in guinea pig skin. J Investig Dermatol. 1987;89:281-6.
78. Chen WR, Adams RL, Bartels KE, Nordquist RE. Chromophore-enhanced in vivo tumor cell destruction using an 808-nm diode laser. Cancer Lett. 1995;94:125-31.
79. Jori G, Schindl L, Schindl A, Polo L. Novel approaches towards a detailed control of the mechanism and efficiency of photosensitized processes in vivo. J Photochem Photobiol A Chem. 1996;102:101-7.
80. Pitsillides CM, Joe EK, Wei X, Anderson R, Lin CP. Selective cell targeting with light-absorbing microparticles and nanoparticles. Biophys J. 2003;84:4023-32.
81. Hainfeld JF, Slatkin DN, Smilowitz HM. The use of gold nanoparticles to enhance radiotherapy in mice. Phys Med Biol. 2004;49:N309.
82. Huang X, El-Sayed IH, Qian W, El-Sayed MA. Cancer cell imaging and photothermal therapy in the near-infrared region by using gold nanorods. J Am Chem Soc. 2006;128:2115-20.
83. Hirsch LR, Stafford R, Bankson J, Sershen S, Rivera B, Price R, et al. Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance. Proc Natl Acad Sci. 2003;100:13549-54.
84. Chen J, Wiley B, Li ZY, Campbell D, Saeki F, Cang H, et al. Gold nanocages: engineering their structure for biomedical applications. Adv Mater. 2005;17:2255-61.
85. Kam NWS, O'Connell M, Wisdom JA, Dai H. Carbon nanotubes as multifunctional biological transporters and near-infrared agents for selective cancer cell destruction. Proc Natl Acad Sci U S A. 2005;102:11600-5.
86. Landsman M, Kwant G, Mook G, Zijlstra W. Light-absorbing properties, stability, and spectral stabilization of indocyanine green. J Appl Physiol. 1976;40:575-83.
87. Chen Y, Gnyawali SC, Wu F, Liu H, Tesiram YA, Abbott A, et al. Magnetic resonance imaging guidance for laser photothermal therapy. J Biomed Opt. 2008;13:044033.
88. You J, Shao R, Wei X, Gupta S, Li C. Near-infrared light triggers release of paclitaxel from biodegradable microspheres: photothermal effect and enhanced antitumor activity. Small. 2010;6:1022-31.
89. Jansen JF, Schoder H, Lee NY, Stambuk HE, Wang Y, Fury MG, et al. Tumor metabolism and perfusion in head and neck squamous cell carcinoma: pretreatment multimodality imaging with 1H magnetic resonance spectroscopy, dynamic contrast-enhanced MRI, and [18F]FDG-PET. Int J Radiat Oncol Biol Phys. 2012;82:299-307.