Biocatalytic release of an anticancer drug from nucleic-acids-capped mesoporous SiO2 using DNA or molecular biomarkers as triggering stimuli

ACS Nano

Volumn 7, Issue 10, 2013, Pages 8455-8468

  Zhang, Zhanxia ^a   Balogh, Dora ^a   Wang, Fuan ^a   Sung, Sohn Yang ^a   Nechushtai, Rachel ^a   Willner, Itamar ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

aptamer; controlled release; exonuclease III; mesoporous SiO2; nanoparticle; nicking enzyme

Indexed keywords

APTAMERS; BREAST CANCER CELLS; CAMPTOTHECIN (CPT); CONTROLLED RELEASE; EXONUCLEASE III; HAIRPIN STRUCTURES; MESOPOROUS SIO; MOLECULAR BIOMARKER;

BIOMOLECULES; CELL DEATH; DNA; ENZYMES; LOCKS (FASTENERS); NANOPARTICLES; NIOBIUM COMPOUNDS; SUBSTRATES;

MESOPOROUS MATERIALS;

ANTINEOPLASTIC AGENT; BIOLOGICAL MARKER; CAMPTOTHECIN; DNA; FLUORESCENT DYE; NUCLEIC ACID; PRIMER DNA; RHODAMINE; RHODAMINE B; SILICON DIOXIDE;

ARTICLE; BIOCATALYSIS; BREAST TUMOR; CHEMISTRY; FEMALE; HUMAN; NUCLEOTIDE SEQUENCE; PATHOLOGY; SPECTROFLUOROMETRY;

ANTINEOPLASTIC AGENTS; BASE SEQUENCE; BIOCATALYSIS; BIOLOGICAL MARKERS; BREAST NEOPLASMS; CAMPTOTHECIN; DNA; DNA PRIMERS; FEMALE; FLUORESCENT DYES; HUMANS; NUCLEIC ACIDS; RHODAMINES; SILICON DIOXIDE; SPECTROMETRY, FLUORESCENCE;

EID: 84887013557     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn403772j     Document Type: Article

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