-
1
-
-
84873710465
-
CK2 phosphorylation of human Sec63 regulates its interaction with Sec62
-
Ampofo E, Welker S, Jung M, Müller L, Greiner M, Zimmermann R, Montenarh M (2013) CK2 phosphorylation of human Sec63 regulates its interaction with Sec62. Biochim Biophys Acta 1830:2938–2945
-
(2013)
Biochim Biophys Acta
, vol.1830
, pp. 2938-2945
-
-
Ampofo, E.1
Welker, S.2
Jung, M.3
Müller, L.4
Greiner, M.5
Zimmermann, R.6
Montenarh, M.7
-
2
-
-
28444474185
-
The gene disrupted in Marinesco-Sjögren syndrome encodes SIL1, an HSPA5 cochaperone
-
Anttonen A-K, Mahjneh I, Hämäläinen RH, Lagier-Tourenne C, Kopra O, Waris L, Anttonen M, Joensuu T, Kalimo H, Paetau A, Tranebjaerg L, Chaigne D, Koenig M, Eeg-Olofsson O, Udd B, Somer M, Somer H, Lehesjoki A-E (2005) The gene disrupted in Marinesco-Sjögren syndrome encodes SIL1, an HSPA5 cochaperone. Nat Genet 37:1309–1311
-
(2005)
Nat Genet
, vol.37
, pp. 1309-1311
-
-
Anttonen, A.-K.1
Mahjneh, I.2
Hämäläinen, R.H.3
Lagier-Tourenne, C.4
Kopra, O.5
Waris, L.6
Anttonen, M.7
Joensuu, T.8
Kalimo, H.9
Paetau, A.10
Tranebjaerg, L.11
Chaigne, D.12
Koenig, M.13
Eeg-Olofsson, O.14
Udd, B.15
Somer, M.16
Somer, H.17
Lehesjoki, A.-E.18
-
3
-
-
34548202772
-
Visiting the ER: The endoplasmic reticulum as a target for therapeutics in traffic related diseases
-
Aridor M (2007) Visiting the ER: the endoplasmic reticulum as a target for therapeutics in traffic related diseases. Adv Drug Deliv Rev 59:759–781
-
(2007)
Adv Drug Deliv Rev
, vol.59
, pp. 759-781
-
-
Aridor, M.1
-
4
-
-
39549101755
-
BiP mutants that are unable to interact with endoplasmic reticulum DnaJ proteins provide insights into interdomain interactions in BiP
-
Awad W, Estrada I, Shen Y, Hendershot LM (2008) BiP mutants that are unable to interact with endoplasmic reticulum DnaJ proteins provide insights into interdomain interactions in BiP. Proc Natl Acad Sci U S A 105:1164–1169
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 1164-1169
-
-
Awad, W.1
Estrada, I.2
Shen, Y.3
Hendershot, L.M.4
-
6
-
-
84863530065
-
Endoplasmic reticulum-mitochondria coupling: Local Ca2+ signalling with functional consequences
-
Bakowski D, Nelson C, Parekh AB (2012) Endoplasmic reticulum-mitochondria coupling: local Ca2+ signalling with functional consequences. Eur J Physiol 464:27–32
-
(2012)
Eur J Physiol
, vol.464
, pp. 27-32
-
-
Bakowski, D.1
Nelson, C.2
Parekh, A.B.3
-
7
-
-
78449234776
-
BiP modulates the affinity of its co-chaperone ERj1 to ribosomes
-
Benedix J, Lajoie P, Jaiswal H, Burgard C, Greiner M, Zimmermann R, Rospert S, Snapp EL, Dudek J (2010) BiP modulates the affinity of its co-chaperone ERj1 to ribosomes. J Biol Chem 285:36427–36433
-
(2010)
J Biol Chem
, vol.285
, pp. 36427-36433
-
-
Benedix, J.1
Lajoie, P.2
Jaiswal, H.3
Burgard, C.4
Greiner, M.5
Zimmermann, R.6
Rospert, S.7
Snapp, E.L.8
Dudek, J.9
-
8
-
-
0036877142
-
The endoplasmic reticulum: A multifunctional signalling organelle
-
Berridge MJ (2002) The endoplasmic reticulum: a multifunctional signalling organelle. Cell Calcium 32:235–249
-
(2002)
Cell Calcium
, vol.32
, pp. 235-249
-
-
Berridge, M.J.1
-
9
-
-
0032728067
-
AScj1p homolog and folding catalysts present in dog pancreas microsomes
-
Bies C, Guth S, Janoschek K, Nastainczyk W, Volkmer J, Zimmermann, R (1999) AScj1p homolog and folding catalysts present in dog pancreas microsomes. Biol Chem 380:1175–1182
-
(1999)
Biol Chem
, vol.380
, pp. 1175-1182
-
-
Bies, C.1
Guth, S.2
Janoschek, K.3
Nastainczyk, W.4
Volkmer, J.5
Zimmermann, R.6
-
10
-
-
2942724434
-
Characterization of pancreatic ERj3p, a homolog of yeast DnaJ-like protein Scj1p
-
Bies C, Blum R, Dudek J, Nastainczyk W, Oberhauser S, Jung M, Zimmermann R (2004) Characterization of pancreatic ERj3p, a homolog of yeast DnaJ-like protein Scj1p. Biol Chem 385:389–395
-
(2004)
Biol Chem
, vol.385
, pp. 389-395
-
-
Bies, C.1
Blum, R.2
Dudek, J.3
Nastainczyk, W.4
Oberhauser, S.5
Jung, M.6
Zimmermann, R.7
-
11
-
-
33644998946
-
ERj1p uses a universal ribosomal adaptor site to coordinate the 80S ribosome at the membrane
-
Blau M, Mullapudi S, Becker T, Dudek J, Zimmermann R, Penczek PA, Beckmann R (2005) ERj1p uses a universal ribosomal adaptor site to coordinate the 80S ribosome at the membrane. Nat Struct Mol Biol 12:1015–1016
-
(2005)
Nat Struct Mol Biol
, vol.12
, pp. 1015-1016
-
-
Blau, M.1
Mullapudi, S.2
Becker, T.3
Dudek, J.4
Zimmermann, R.5
Penczek, P.A.6
Beckmann, R.7
-
12
-
-
0016753216
-
Transfer of proteins across membranes I Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma
-
Blobel G, Dobberstein B (1975a) Transfer of proteins across membranes I Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma. J Cell Biol 67:835–851
-
(1975)
J Cell Biol
, vol.67
, pp. 835-851
-
-
Blobel, G.1
Dobberstein, B.2
-
13
-
-
0016752682
-
Transfer of proteins across membranes II. Reconstitution of functional rough microsomes from heterologous components
-
Blobel G, Dobberstein B (1975b) Transfer of proteins across membranes II. Reconstitution of functional rough microsomes from heterologous components. J Cell Biol 67:852–862
-
(1975)
J Cell Biol
, vol.67
, pp. 852-862
-
-
Blobel, G.1
Dobberstein, B.2
-
14
-
-
0022536233
-
Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas
-
Bole DG, Hendershot LM, Kearney JF (1986) Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas. J Cell Biol 102:1558–1566
-
(1986)
J Cell Biol
, vol.102
, pp. 1558-1566
-
-
Bole, D.G.1
Hendershot, L.M.2
Kearney, J.F.3
-
15
-
-
0041328471
-
Wolcott-Rallison syndrome: Pathogenic insights into neonatal diabetes from new mutation and expression studies of EIF2AK3
-
Brickwood S, Bonthron DT, Al-Gazali LI, Piper K, Hearn T, Wilson DI, Hanley NA (2003) Wolcott-Rallison syndrome: pathogenic insights into neonatal diabetes from new mutation and expression studies of EIF2AK3. J Med Genet 40:685–689
-
(2003)
J Med Genet
, vol.40
, pp. 685-689
-
-
Brickwood, S.1
Bonthron, D.T.2
Al-Gazali, L.I.3
Piper, K.4
Hearn, T.5
Wilson, D.I.6
Hanley, N.A.7
-
16
-
-
0028893336
-
Isolation of a mouse cDNA encoding MTJ1, a new murine member of the DnaJ family of proteins
-
Brightman SE, Blatch GL, Zetter BR (1995) Isolation of a mouse cDNA encoding MTJ1, a new murine member of the DnaJ family of proteins. Gene 153:249–254
-
(1995)
Gene
, vol.153
, pp. 249-254
-
-
Brightman, S.E.1
Blatch, G.L.2
Zetter, B.R.3
-
17
-
-
84868574593
-
Disulfide bond formation in the mammalian endoplasmic reticulum
-
Bulleid NJ (2012) Disulfide bond formation in the mammalian endoplasmic reticulum. Cold Spring Harb Perspect Biol 4:a013219
-
(2012)
Cold Spring Harb Perspect Biol
, vol.4
-
-
Bulleid, N.J.1
-
18
-
-
0026782109
-
Calreticulin in T-lymphocytes. Identification of calreticulin in T-lymphocytes and demonstration that activation of T-cells correlates with increased levels of calreticulin mRNA and protein
-
Burns K, Helgason CD, Bleakley RC, Michalak M (1992) Calreticulin in T-lymphocytes. Identification of calreticulin in T-lymphocytes and demonstration that activation of T-cells correlates with increased levels of calreticulin mRNA and protein. J Biol Chem 267:19039–19042
-
(1992)
J Biol Chem
, vol.267
, pp. 19039-19042
-
-
Burns, K.1
Helgason, C.D.2
Bleakley, R.C.3
Michalak, M.4
-
19
-
-
84866455655
-
ADP ribosylation adapts an ER chaperone response to short-term fluctuations in unfolded protein load
-
Chambers JE, Petrova K, Tomba G, Vendruscolo M, Ron D (2012) ADP ribosylation adapts an ER chaperone response to short-term fluctuations in unfolded protein load. J Cell Biol 198:371–385
-
(2012)
J Cell Biol
, vol.198
, pp. 371-385
-
-
Chambers, J.E.1
Petrova, K.2
Tomba, G.3
Vendruscolo, M.4
Ron, D.5
-
20
-
-
0347033285
-
BAP, a mammalian BiP associated protein, is a nucleotide exchange factor that regulates the ATPase activity of BiP
-
Chung KT, Shen Y, Hendershot H (2002) BAP, a mammalian BiP associated protein, is a nucleotide exchange factor that regulates the ATPase activity of BiP. J Biol Chem 277:47557–47563
-
(2002)
J Biol Chem
, vol.277
, pp. 47557-47563
-
-
Chung, K.T.1
Shen, Y.2
Hendershot, H.3
-
21
-
-
0037428470
-
ERdj5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stress
-
Cunnea PM, Miranda-Vizuete A, Bertoli G, Simmen T, Damdimopoulos AE, Hermann S, Leinonen S, Huikko MP, Gustafsson J-A, Sitia R, Spyrou G (2003) ERdj5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stress. J Biol Chem 278:1059–1066
-
(2003)
J Biol Chem
, vol.278
, pp. 1059-1066
-
-
Cunnea, P.M.1
Miranda-Vizuete, A.2
Bertoli, G.3
Simmen, T.4
Damdimopoulos, A.E.5
Hermann, S.6
Leinonen, S.7
Huikko, M.P.8
Gustafsson, J.-A.9
Sitia, R.10
Spyrou, G.11
-
22
-
-
2642528473
-
Mutations in SEC63 cause autosomal dominant polycystic liver disease
-
Davila S, Furu L, Gharavi AG, Tian X, Onoe T, Qian Q, Li A, Cai Y, Kamath PS, King BF, Azurmendi PJ, Tahvanainen P, Kääriäinen H, Höckerstedt K, Devuyst O, Pirson Y, Martin RS, Lifton RP, Tahvanainen E, Tores VE, Somlo S (2004) Mutations in SEC63 cause autosomal dominant polycystic liver disease. Nat Genet 36:575–577
-
(2004)
Nat Genet
, vol.36
, pp. 575-577
-
-
Davila, S.1
Furu, L.2
Gharavi, A.G.3
Tian, X.4
Onoe, T.5
Qian, Q.6
Li, A.7
Cai, Y.8
Kamath, P.S.9
King, B.F.10
Azurmendi, P.J.11
Tahvanainen, P.12
Kääriäinen, H.13
Höckerstedt, K.14
Devuyst, O.15
Pirson, Y.16
Martin, R.S.17
Lifton, R.P.18
Tahvanainen, E.19
Tores, V.E.20
Somlo, S.21
more..
-
23
-
-
0026022577
-
Participation of a novel 88-kD protein in the biogenesis of murine class I histocompatibility proteins
-
Degen E, Williams DB (1991) Participation of a novel 88-kD protein in the biogenesis of murine class I histocompatibility proteins. J Cell Biol 112:1099–1115
-
(1991)
J Cell Biol
, vol.112
, pp. 1099-1115
-
-
Degen, E.1
Williams, D.B.2
-
24
-
-
48249155627
-
ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C
-
Dong M, Bridges JP, Apsley K, Xu Y, Weaveret TE (2008) ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C. Mol Biol Cell 19:2620–2630
-
(2008)
Mol Biol Cell
, vol.19
, pp. 2620-2630
-
-
Dong, M.1
Bridges, J.P.2
Apsley, K.3
Xu, Y.4
Weaveret, T.E.5
-
25
-
-
18444378736
-
A novel type of cochaperone mediates transmembrane recruitment of DnaKlike chaperones to ribosomes
-
Dudek J, Volkmer J, Bies C, Guth S, Müller A, Lerner M, Feick P, Schäfer KH, Morgenstern E, Hennessy F, Blatch GL, Janoscheck K, Heim N, Scholtes P, Frien M, Nastainczyk W, Zimmermann R (2002) A novel type of cochaperone mediates transmembrane recruitment of DnaKlike chaperones to ribosomes. EMBO J 21:2958–2967
-
(2002)
EMBO J
, vol.21
, pp. 2958-2967
-
-
Dudek, J.1
Volkmer, J.2
Bies, C.3
Guth, S.4
Müller, A.5
Lerner, M.6
Feick, P.7
Schäfer, K.H.8
Morgenstern, E.9
Hennessy, F.10
Blatch, G.L.11
Janoscheck, K.12
Heim, N.13
Scholtes, P.14
Frien, M.15
Nastainczyk, W.16
Zimmermann, R.17
-
26
-
-
33645011120
-
ERj1p plays a basic role in protein biogenesis at the endoplasmic reticulum
-
Dudek J, Greiner M, Müller, A, Hendershot LM, Kopsch K, Nastainczyk W, Zimmermann R (2005) ERj1p plays a basic role in protein biogenesis at the endoplasmic reticulum. Nat Struct Mol Biol 12:1008–1014
-
(2005)
Nat Struct Mol Biol
, vol.12
, pp. 1008-1014
-
-
Dudek, J.1
Greiner, M.2
Müller, A.3
Hendershot, L.M.4
Kopsch, K.5
Nastainczyk, W.6
Zimmermann, R.7
-
27
-
-
84876011203
-
Endoplasmic reticulum structure and interconnections with other organelles
-
English AR, Voeltz GK (2013) Endoplasmic reticulum structure and interconnections with other organelles. Cold Spring Harb Perspect Biol 5:a013227
-
(2013)
Cold Spring Harb Perspect Biol
, vol.5
-
-
English, A.R.1
Voeltz, G.K.2
-
28
-
-
78650905148
-
Interaction of calmodulin with Sec61a limits Ca2+ leakage from the endoplasmic reticulum
-
Erdmann F, Schäuble N, Lang S, Jung M, Honigmann A, Ahmad M, Dudek J, Benedix J, Harsmann A, Kopp A, Helms V, Cavalié A, Wagner R, Zimmermann R (2011) Interaction of calmodulin with Sec61a limits Ca2+ leakage from the endoplasmic reticulum. EMBO J 30:17–31
-
(2011)
EMBO J
, vol.30
, pp. 17-31
-
-
Erdmann, F.1
Schäuble, N.2
Lang, S.3
Jung, M.4
Honigmann, A.5
Ahmad, M.6
Dudek, J.7
Benedix, J.8
Harsmann, A.9
Kopp, A.10
Helms, V.11
Cavalié, A.12
Wagner, R.13
Zimmermann, R.14
-
29
-
-
20644443287
-
Molecular staging or surival prediction of colorectal cancer patients
-
Eschrich S, Yang I, Bloom G, Kwong KY, Boulware D, Cantor A, Coppola D, Kruhoffer M, Aaltonen L, Orntoft TF, Quackenbush J, Yeatman TJ (2005) Molecular staging or surival prediction of colorectal cancer patients. J Clin Oncol 23:3526–3535
-
(2005)
J Clin Oncol
, vol.23
, pp. 3526-3535
-
-
Eschrich, S.1
Yang, I.2
Bloom, G.3
Kwong, K.Y.4
Boulware, D.5
Cantor, A.6
Coppola, D.7
Kruhoffer, M.8
Aaltonen, L.9
Orntoft, T.F.10
Quackenbush, J.11
Yeatman, T.J.12
-
30
-
-
79959725455
-
A genetic interaction network of five genes for human polycystic kidney and liver disease defines polycystin-1 as the central determinant of cyst formation
-
Fedeles SV, Tian X, Gallagher A-R, Mitobe M, Nishio S, Lee SH, Cai Y, Geng L, Crews CM, Somlo S (2011) A genetic interaction network of five genes for human polycystic kidney and liver disease defines polycystin-1 as the central determinant of cyst formation. Nat Genet 43:639–647
-
(2011)
Nat Genet
, vol.43
, pp. 639-647
-
-
Fedeles, S.V.1
Tian, X.2
Gallagher, A.-R.3
Mitobe, M.4
Nishio, S.5
Lee, S.H.6
Cai, Y.7
Geng, L.8
Crews, C.M.9
Somlo, S.10
-
31
-
-
33845656359
-
Passive calcium leak via translocon is a first step for iPLA2-pathway regulated store operated channels activation
-
Flourakis M, Van Coppenolle F, Lehen’kyi V, Beck B, Skryma R (2006) Passive calcium leak via translocon is a first step for iPLA2-pathway regulated store operated channels activation. FASEB J 20:1215–1217
-
(2006)
FASEB J
, vol.20
, pp. 1215-1217
-
-
Flourakis, M.1
Van Coppenolle, F.2
Lehen’Kyi, V.3
Beck, B.4
Skryma, R.5
-
32
-
-
84894270152
-
Deficiency of the BiP cochaperone ERdj4 causes constitutive endoplasmic reticulum stress and metabolic defects
-
Fritz JM, Dong M, Apsley KS, Martin EP, Na CL, Sitaraman S, Weaver TE (2014) Deficiency of the BiP cochaperone ERdj4 causes constitutive endoplasmic reticulum stress and metabolic defects. Mol Biol Cell 25:431–440
-
(2014)
Mol Biol Cell
, vol.25
, pp. 431-440
-
-
Fritz, J.M.1
Dong, M.2
Apsley, K.S.3
Martin, E.P.4
Na, C.L.5
Sitaraman, S.6
Weaver, T.E.7
-
33
-
-
34248549003
-
GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis
-
Fu Y, Li J, Lee AS (2007) GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis. Cancer Res 67:3734–3740
-
(2007)
Cancer Res
, vol.67
, pp. 3734-3740
-
-
Fu, Y.1
Li, J.2
Lee, A.S.3
-
34
-
-
84870735655
-
Endoplasmic reticulum stress sensing in the unfolded protein response
-
Gardner BM, Pincus D, Gotthardt K, Gallagher CM, Walter P (2013) Endoplasmic reticulum stress sensing in the unfolded protein response. Cold Spring Harb Perspect Biol 5:a013169
-
(2013)
Cold Spring Harb Perspect Biol
, vol.5
-
-
Gardner, B.M.1
Pincus, D.2
Gotthardt, K.3
Gallagher, C.M.4
Walter, P.5
-
35
-
-
34248573016
-
Both translocon and a cation channel are involved in the passive Ca2 + leak from the endoplasmic reticulum: A mechanistic study on rat liver microsomes
-
Giunti R, Gamberucci A, Fulceri R, Banhegyi G (2007) Both translocon and a cation channel are involved in the passive Ca2 + leak from the endoplasmic reticulum: a mechanistic study on rat liver microsomes. Arch Biochem Biophys 462:115–121
-
(2007)
Arch Biochem Biophys
, vol.462
, pp. 115-121
-
-
Giunti, R.1
Gamberucci, A.2
Fulceri, R.3
Banhegyi, G.4
-
36
-
-
0026466143
-
A mammalian homolog of SEC61p and SECYp is associated with ribosomes and nascent polypeptides during translocation
-
Görlich D, Prehn S, Hartmann E, Kalies K-U, Rapoport TA (1992) A mammalian homolog of SEC61p and SECYp is associated with ribosomes and nascent polypeptides during translocation. Cell 71:489–503
-
(1992)
Cell
, vol.71
, pp. 489-503
-
-
Görlich, D.1
Prehn, S.2
Hartmann, E.3
Kalies, K.-U.4
Rapoport, T.A.5
-
37
-
-
69949140291
-
ERj1 is a substrate of phosphorylation by CK2
-
Götz G, Müller A, Montenarh M, Zimmermann R, Dudek J (2009) ERj1 is a substrate of phosphorylation by CK2. Biochem Biophys Res Commun 388:637–642
-
(2009)
Biochem Biophys Res Commun
, vol.388
, pp. 637-642
-
-
Götz, G.1
Müller, A.2
Montenarh, M.3
Zimmermann, R.4
Dudek, J.5
-
38
-
-
79953199064
-
Silencing of the SEC62 gene inhibits migratory and invasive potential of various tumor cells
-
Greiner M, Kreutzer B, Jung V, Grobholz R, Hasenfus A, Stöhr R, Franz R, Tornillo L, Dudek J, Stöckle M, Unteregger G, Kamradt J, Wullich B, Zimmermann R (2011a) Silencing of the SEC62 gene inhibits migratory and invasive potential of various tumor cells. Int J Cancer 128:2284–2295
-
(2011)
Int J Cancer
, vol.128
, pp. 2284-2295
-
-
Greiner, M.1
Kreutzer, B.2
Jung, V.3
Grobholz, R.4
Hasenfus, A.5
Stöhr, R.6
Franz, R.7
Tornillo, L.8
Dudek, J.9
Stöckle, M.10
Unteregger, G.11
Kamradt, J.12
Wullich, B.13
Zimmermann, R.14
-
39
-
-
79955865241
-
Sec62 protein level is crucial for ER-stress tolerance of prostate cancer
-
Greiner M, Kreutzer B, Lang S, Jung V, Cavalié A, Unteregger G, Zimmermann R, Wullich B (2011b) Sec62 protein level is crucial for ER-stress tolerance of prostate cancer. The Prostate 71:1074–1083
-
(2011)
The Prostate
, vol.71
, pp. 1074-1083
-
-
Greiner, M.1
Kreutzer, B.2
Lang, S.3
Jung, V.4
Cavalié, A.5
Unteregger, G.6
Zimmermann, R.7
Wullich, B.8
-
40
-
-
34848895197
-
Structural determinants of lateral gate opening in the protein translocon
-
Gumbart J, Schulten K (2007) Structural determinants of lateral gate opening in the protein translocon. Biochemistry 46:11147–11157
-
(2007)
Biochemistry
, vol.46
, pp. 11147-11157
-
-
Gumbart, J.1
Schulten, K.2
-
41
-
-
0021076098
-
Immunoglobulin heavy chain binding protein
-
Haas IG, Wabl M (1983) Immunoglobulin heavy chain binding protein. Nature 306:387–389
-
(1983)
Nature
, vol.306
, pp. 387-389
-
-
Haas, I.G.1
Wabl, M.2
-
42
-
-
84885230363
-
Systematic interrogation of 3q26 identifies TLOC1 and SKL as cancer drivers
-
Hagerstrand D, Tong A, Schumacher SE, Ilic N, Shen RR, Cheung HW, Vazquez F, Shrestha Y, Kim SY, Giacomelli AO, Rosenbluh J, Schinel AC, Spardy NA, Barbie DA, Mermel CH, Weir BA, Garraway LA, Tamayo P, Mesirov JP, Beroukhim R, Hahn WC (2013) Systematic interrogation of 3q26 identifies TLOC1 and SKL as cancer drivers. Cancer Discov 3:1044–1057
-
(2013)
Cancer Discov
, vol.3
, pp. 1044-1057
-
-
Hagerstrand, D.1
Tong, A.2
Schumacher, S.E.3
Ilic, N.4
Shen, R.R.5
Cheung, H.W.6
Vazquez, F.7
Shrestha, Y.8
Kim, S.Y.9
Giacomelli, A.O.10
Rosenbluh, J.11
Schinel, A.C.12
Spardy, N.A.13
Barbie, D.A.14
Mermel, C.H.15
Weir, B.A.16
Garraway, L.A.17
Tamayo, P.18
Mesirov, J.P.19
Beroukhim, R.20
Hahn, W.C.21
more..
-
43
-
-
79951491416
-
Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5
-
Hagiwara M, Maegawa K-i, Suzuki M, Ushioda R, Araki K, Matsumoto JH, Nagata K, Inaba K (2011) Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5. Mol Cell 41:432–444
-
(2011)
Mol Cell
, vol.41
, pp. 432-444
-
-
Hagiwara, M.1
K-I, M.2
Suzuki, M.3
Ushioda, R.4
Araki, K.5
Matsumoto, J.H.6
Nagata, K.7
Inaba, K.8
-
44
-
-
0033590451
-
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
-
Harding HP, Zhang Y, Ron D (1999) Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 397:271–274
-
(1999)
Nature
, vol.397
, pp. 271-274
-
-
Harding, H.P.1
Zhang, Y.2
Ron, D.3
-
45
-
-
0027958547
-
Evolutionary conservation of components of the protein translocation complex
-
Hartmann E, Sommer T, Prehn S, Görlich D, Jentsch S, Rapoport TA (1994) Evolutionary conservation of components of the protein translocation complex. Nature 367:654–657
-
(1994)
Nature
, vol.367
, pp. 654-657
-
-
Hartmann, E.1
Sommer, T.2
Prehn, S.3
Görlich, D.4
Jentsch, S.5
Rapoport, T.A.6
-
46
-
-
35549006797
-
Sigma-1 receptor chaperones at the ER- mitochondrion interface regulate Ca(2+) signaling and cell survival
-
Hayashi T, Su T-P (2007) Sigma-1 receptor chaperones at the ER- mitochondrion interface regulate Ca(2+) signaling and cell survival. Cell 131:596–610
-
(2007)
Cell
, vol.131
, pp. 596-610
-
-
Hayashi, T.1
Su, T.-P.2
-
48
-
-
22344447035
-
Not all J domains are created equal: Implications for the specificity of Hsp40-Hsp70 interactions
-
Hennessy F, Nicoll WS, Zimmermann R, Cheetham ME, Blatch GL (2005) Not all J domains are created equal: implications for the specificity of Hsp40-Hsp70 interactions. Protein Sci 14:1697–1709
-
(2005)
Protein Sci
, vol.14
, pp. 1697-1709
-
-
Hennessy, F.1
Nicoll, W.S.2
Zimmermann, R.3
Cheetham, M.E.4
Blatch, G.L.5
-
49
-
-
0037462652
-
JPDI, a novel endoplasmic reticulum-resident protein containing both a BiP-interacting J-domain and thioredoxin-like motifs
-
Hosoda A, Kimata Y, Tsuru A, Kohno K (2003) JPDI, a novel endoplasmic reticulum-resident protein containing both a BiP-interacting J-domain and thioredoxin-like motifs. J Biol Chem 278:2669–2676
-
(2003)
J Biol Chem
, vol.278
, pp. 2669-2676
-
-
Hosoda, A.1
Kimata, Y.2
Tsuru, A.3
Kohno, K.4
-
50
-
-
55549139747
-
Regulated release of ERdj3 from unfolded proteins by BiP
-
Jin Y, Awad W, Petrova K, Hendershot LM (2008) Regulated release of ERdj3 from unfolded proteins by BiP. EMBO J 27:2873–2882
-
(2008)
EMBO J
, vol.27
, pp. 2873-2882
-
-
Jin, Y.1
Awad, W.2
Petrova, K.3
Hendershot, L.M.4
-
51
-
-
58549098933
-
Erdj3, a luminal ER DnaJ homologue, binds directly to unfolded proteins in the mammalian ER: Identification of critical residues
-
Jin Y, Zhuang M, Hendershot LM (2009) Erdj3, a luminal ER DnaJ homologue, binds directly to unfolded proteins in the mammalian ER: identification of critical residues. Biochemistry 48:41–49
-
(2009)
Biochemistry
, vol.48
, pp. 41-49
-
-
Jin, Y.1
Zhuang, M.2
Hendershot, L.M.3
-
52
-
-
33645666218
-
Genomic and expression analysis of the 3q25-q26 amplicon reveals TLOC1/SEC62 as a probable target gene in prostate cancer
-
Jung V, Kamradt J, Kindich R, Jung M, Mueller M, Schulz WA, Engers R, Stoeckle M, Zimmermann R, Wullich B (2006) Genomic and expression analysis of the 3q25-q26 amplicon reveals TLOC1/SEC62 as a probable target gene in prostate cancer. Mol Cancer Res 4:169–176
-
(2006)
Mol Cancer Res
, vol.4
, pp. 169-176
-
-
Jung, V.1
Kamradt, J.2
Kindich, R.3
Jung, M.4
Mueller, M.5
Schulz, W.A.6
Engers, R.7
Stoeckle, M.8
Zimmermann, R.9
Wullich, B.10
-
53
-
-
33751333201
-
Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway
-
Kang SW, Ran NS, Kim SJ, Garrison JL, Taunton J, Hegde RS (2006) Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway. Cell 127:999–1013
-
(2006)
Cell
, vol.127
, pp. 999-1013
-
-
Kang, S.W.1
Ran, N.S.2
Kim, S.J.3
Garrison, J.L.4
Taunton, J.5
Hegde, R.S.6
-
54
-
-
10744233077
-
ORP150/HSP12A regulates purkinje cell survival: A role for endoplasmic reticulum stress in cerebellar development
-
Kitao Y, Hashimoto K, Matsuyama T, Iso H, Tamatani T, Hori O, Stern DM, Kano M, Ozawa K, Ogawa S (2004) ORP150/HSP12A regulates purkinje cell survival: a role for endoplasmic reticulum stress in cerebellar development. J Neurosci 24:1486–1496
-
(2004)
J Neurosci
, vol.24
, pp. 1486-1496
-
-
Kitao, Y.1
Hashimoto, K.2
Matsuyama, T.3
Iso, H.4
Tamatani, T.5
Hori, O.6
Stern, D.M.7
Kano, M.8
Ozawa, K.9
Ogawa, S.10
-
55
-
-
67749122635
-
An ERmitochondria tethering complex revealed by a synthetic biology screen
-
Kornmann B, Currie E, Collins SR, Schuldiner M, Nunnari J, Weissman JS, Walter P (2009) An ERmitochondria tethering complex revealed by a synthetic biology screen. Science 325:477–481
-
(2009)
Science
, vol.325
, pp. 477-481
-
-
Kornmann, B.1
Currie, E.2
Collins, S.R.3
Schuldiner, M.4
Nunnari, J.5
Weissman, J.S.6
Walter, P.7
-
56
-
-
1642524204
-
The SANT2 domain of murine tumor cell DnaJ-like protein 1 human homologue interacts with α1-antichymotrypsin and kinetically interferes with its serpin inhibitory activity
-
Kroczynska B, Evangelista CM, Samant SS, Elguindi EC, Blond SY (2004) The SANT2 domain of murine tumor cell DnaJ-like protein 1 human homologue interacts with α1-antichymotrypsin and kinetically interferes with its serpin inhibitory activity. J Biol Chem 279:11432–11443
-
(2004)
J Biol Chem
, vol.279
, pp. 11432-11443
-
-
Kroczynska, B.1
Evangelista, C.M.2
Samant, S.S.3
Elguindi, E.C.4
Blond, S.Y.5
-
57
-
-
0037323012
-
MDG1/ERdj4, an ER-resident DnaJ family member, suppresses cell death induced by ER stress
-
Kurisu J, Honma A, Miyajima H, Kondo S Okumura M, Imaizumi K (2003) MDG1/ERdj4, an ER-resident DnaJ family member, suppresses cell death induced by ER stress. Genes Cells 8:189–202
-
(2003)
Genes Cells
, vol.8
, pp. 189-202
-
-
Kurisu, J.1
Honma, A.2
Miyajima, H.3
Kondo S Okumura, M.4
Imaizumi, K.5
-
58
-
-
20144386666
-
Pancreatic beta-cell failure and diabetes in mice with a deletion mutation of the endoplasmic reticulum molecular chaperone gene P58IPK
-
Ladiges WC, Knoblaugh SE, Morton JF, Korth MJ, Sopher BL, Baskin CR, MacAuley A, Goodman AG, LeBoeuf RC, Katze MG (2005) Pancreatic beta-cell failure and diabetes in mice with a deletion mutation of the endoplasmic reticulum molecular chaperone gene P58IPK. Diabetes 54:1074–1081
-
(2005)
Diabetes
, vol.54
, pp. 1074-1081
-
-
Ladiges, W.C.1
Knoblaugh, S.E.2
Morton, J.F.3
Korth, M.J.4
Sopher, B.L.5
Baskin, C.R.6
Macauley, A.7
Goodman, A.G.8
Leboeuf, R.C.9
Katze, M.G.10
-
59
-
-
84858042337
-
Erdj4 protein is a soluble endoplasmic reticulum (ER) DnaJ family protein that interacts with ER-associated degradation machinery
-
Lai CW, Otero JH, Hendershot LM, Snapp E (2012) Erdj4 protein is a soluble endoplasmic reticulum (ER) DnaJ family protein that interacts with ER-associated degradation machinery. J Biol Chem 287:7969–7978
-
(2012)
J Biol Chem
, vol.287
, pp. 7969-7978
-
-
Lai, C.W.1
Otero, J.H.2
Hendershot, L.M.3
Snapp, E.4
-
60
-
-
79955709651
-
Sec61 complexes form ubiquitous ER Ca2 + leak channels
-
Lang S, Erdmann F, Jung M, Wagner R, Cavalié A, Zimmermann R (2011) Sec61 complexes form ubiquitous ER Ca2 + leak channels. Channels 5:228–235
-
(2011)
Channels
, vol.5
, pp. 228-235
-
-
Lang, S.1
Erdmann, F.2
Jung, M.3
Wagner, R.4
Cavalié, A.5
Zimmermann, R.6
-
61
-
-
84863092048
-
Different effects of Sec61a-, Sec62 and Sec63-depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells
-
Lang S, Benedix J, Fedeles SV, Schorr S, Schirra C, Schäuble N, Jalal C, Greiner M, Haßdenteufel S, Tatzelt J, Kreutzer B, Edelmann L, Krause E, Rettig J, Somlo S, Zimmermann R, Dudek J (2012) Different effects of Sec61a-, Sec62 and Sec63-depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells. J Cell Sci 125:1958–1969
-
(2012)
J Cell Sci
, vol.125
, pp. 1958-1969
-
-
Lang, S.1
Benedix, J.2
Fedeles, S.V.3
Schorr, S.4
Schirra, C.5
Schäuble, N.6
Jalal, C.7
Greiner, M.8
Haßdenteufel, S.9
Tatzelt, J.10
Kreutzer, B.11
Edelmann, L.12
Krause, E.13
Rettig, J.14
Somlo, S.15
Zimmermann, R.16
Dudek, J.17
-
62
-
-
0027136174
-
The 170-kDa glucoseregulated stress protein is an endoplasmic reticulum protein that binds immunoglobulin
-
Lin H-Y, Masso-Welch P, Di Y-P, Cai J-W, Shen J-W, Subjeck JR (1993) The 170-kDa glucoseregulated stress protein is an endoplasmic reticulum protein that binds immunoglobulin. Mol Biol Cell 4:1109–1119
-
(1993)
Mol Biol Cell
, vol.4
, pp. 1109-1119
-
-
Lin, H.-Y.1
Masso-Welch, P.2
Di, Y.-P.3
Cai, J.-W.4
Shen, J.-W.5
Subjeck, J.R.6
-
63
-
-
84862908615
-
Sec62 bridges the gap from 3q amplification to molecular cell biology in non-small cell lung cancer
-
Linxweiler M, Linxweiler J, Barth M, Benedix J, Jung V, Kim Y-J, Bohle R, Zimmermann R, Greiner M (2012) Sec62 bridges the gap from 3q amplification to molecular cell biology in non-small cell lung cancer. Am J Pathol 180:473–483
-
(2012)
Am J Pathol
, vol.180
, pp. 473-483
-
-
Linxweiler, M.1
Linxweiler, J.2
Barth, M.3
Benedix, J.4
Jung, V.5
Kim, Y.-J.6
Bohle, R.7
Zimmermann, R.8
Greiner, M.9
-
64
-
-
84889074999
-
Targeting cell migration and the ER stress response with calmodulin antagonists: A clinically tested small molecule phenocopy of SEC62 gene silencing in human tumor cells
-
Linxweiler M, Schorr S, Jung M, Schäuble N, Linxweiler J, Langer F, Schäfers H-J, Cavalié A, Zimmermann R, Greiner M (2013) Targeting cell migration and the ER stress response with calmodulin antagonists: A clinically tested small molecule phenocopy of SEC62 gene silencing in human tumor cells. BMC–Cancer 13:574
-
(2013)
BMC–Cancer
, vol.13
-
-
Linxweiler, M.1
Schorr, S.2
Jung, M.3
Schäuble, N.4
Linxweiler, J.5
Langer, F.6
Schäfers, H.-J.7
Cavalié, A.8
Zimmermann, R.9
Greiner, M.10
-
65
-
-
77449130121
-
A point mutation in Sec61 α leads to Diabetes and Hepatosteatisis in Mice
-
Lloyd DJ, Wheeler MC, Gekakis N (2010) A point mutation in Sec61 α leads to Diabetes and Hepatosteatisis in Mice. Diabetes 59:460–470
-
(2010)
Diabetes
, vol.59
, pp. 460-470
-
-
Lloyd, D.J.1
Wheeler, M.C.2
Gekakis, N.3
-
66
-
-
0037135534
-
Basal and physiological Ca2+ leak from the endoplasmic reticulum of pancreatic acinar cells. Second messengeractivated channels and translocons
-
Lomax RB, Camello C, Van Coppenolle F, Petersen OH, Tepikin AV (2002) Basal and physiological Ca2+ leak from the endoplasmic reticulum of pancreatic acinar cells. Second messengeractivated channels and translocons. J Biol Chem 277:26479–26485
-
(2002)
J Biol Chem
, vol.277
, pp. 26479-26485
-
-
Lomax, R.B.1
Camello, C.2
Van Coppenolle, F.3
Petersen, O.H.4
Tepikin, A.V.5
-
67
-
-
33746500168
-
GRP78/BiP is required for cell proliferation and protecting the inner cell mass from apoptosis during early mouse embryonic development
-
Luo S, Mao C, Lee B, Lee AS (2006) GRP78/BiP is required for cell proliferation and protecting the inner cell mass from apoptosis during early mouse embryonic development. Mol Cell Biol 15:5688–5697
-
(2006)
Mol Cell Biol
, vol.15
, pp. 5688-5697
-
-
Luo, S.1
Mao, C.2
Lee, B.3
Lee, A.S.4
-
68
-
-
0028809495
-
Interaction between BiP and Sec63p is required for the completion of protein translocation into the ER of Saccharomyces cerevisiae
-
Lyman SK, Schekman R (1995) Interaction between BiP and Sec63p is required for the completion of protein translocation into the ER of Saccharomyces cerevisiae. J Cell Biol 131:1163–1171
-
(1995)
J Cell Biol
, vol.131
, pp. 1163-1171
-
-
Lyman, S.K.1
Schekman, R.2
-
69
-
-
0030970268
-
Binding of secretory precursor polypeptides to a translocon subcomplex is regulated by BiP
-
Lyman SK, Schekman R (1997) Binding of secretory precursor polypeptides to a translocon subcomplex is regulated by BiP. Cell 88:85–96
-
(1997)
Cell
, vol.88
, pp. 85-96
-
-
Lyman, S.K.1
Schekman, R.2
-
70
-
-
0035966320
-
The unfolding tale of the unfolded protein response
-
Ma Y, Hendershot LM (2001) The unfolding tale of the unfolded protein response. Cell 107:827–830
-
(2001)
Cell
, vol.107
, pp. 827-830
-
-
Ma, Y.1
Hendershot, L.M.2
-
71
-
-
34447548232
-
Molecular chaperones: Multiple functions, pathologies, and potential applications
-
Macario AJ, Conway de Macario E (2007) Molecular chaperones: multiple functions, pathologies, and potential applications. Front Biosci 12:2588–2600
-
(2007)
Front Biosci
, vol.12
, pp. 2588-2600
-
-
Macario, A.J.1
De Conway Macario, E.2
-
72
-
-
62549154503
-
Intricate links between ER stress and apoptosis
-
Madeo F, Kroemer G (2009) Intricate links between ER stress and apoptosis. Mol Cell 33:669–670
-
(2009)
Mol Cell
, vol.33
, pp. 669-670
-
-
Madeo, F.1
Kroemer, G.2
-
73
-
-
0034640293
-
Mammalian Sec61 is associated with Sec62 and Sec63
-
Mayer H-A, Grau H, Kraft R, Prehn S, Kalies K-U, Hartmann E (2000) Mammalian Sec61 is associated with Sec62 and Sec63. J Biol Chem 275:14550–14557
-
(2000)
J Biol Chem
, vol.275
, pp. 14550-14557
-
-
Mayer, H.-A.1
Grau, H.2
Kraft, R.3
Prehn, S.4
Kalies, K.-U.5
Hartmann, E.6
-
74
-
-
0036911213
-
A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins
-
Meunier L, Usherwood Y-K, Chung KT, Hendershot LM (2002) A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins. Mol Biol Cell 13:4456–4469
-
(2002)
Mol Biol Cell
, vol.13
, pp. 4456-4469
-
-
Meunier, L.1
Usherwood, Y.-K.2
Chung, K.T.3
Hendershot, L.M.4
-
75
-
-
34447650984
-
Aberrant quality control in the endoplasmic reticulum impairs the biosynthesis of pulmonary surfactant in mice expressing mutant BiP
-
Mimura N, Hamada H, Kashio M, Jin H, Toyama Y, Kimura K, Iida M, Goto S, Saisho H, Toshimori K, Koseki H, Aoe T (2007) Aberrant quality control in the endoplasmic reticulum impairs the biosynthesis of pulmonary surfactant in mice expressing mutant BiP. Cell Deat Differ 14:1475–1485
-
(2007)
Cell Deat Differ
, vol.14
, pp. 1475-1485
-
-
Mimura, N.1
Hamada, H.2
Kashio, M.3
Jin, H.4
Toyama, Y.5
Kimura, K.6
Iida, M.7
Goto, S.8
Saisho, H.9
Toshimori, K.10
Koseki, H.11
Aoe, T.12
-
76
-
-
0036644869
-
Instabilotyping reveals unique mutational spectra in microsatellite-unstable gastric cancers
-
Mori Y, Sato F, Selaru FM, Olaru A, Perry K, Kimos MC, Tamura G, Matsubara N, Wang S, Xu Y, Yin J, Zou T-T, Leggett B, Young J, Nukiwa T, Stine OC, Abraham JM, Shibata D, Meltzer SJ (2002) Instabilotyping reveals unique mutational spectra in microsatellite-unstable gastric cancers. Cancer Res 62:3641–3645
-
(2002)
Cancer Res
, vol.62
, pp. 3641-3645
-
-
Mori, Y.1
Sato, F.2
Selaru, F.M.3
Olaru, A.4
Perry, K.5
Kimos, M.C.6
Tamura, G.7
Matsubara, N.8
Wang, S.9
Xu, Y.10
Yin, J.11
Zou, T.-T.12
Leggett, B.13
Young, J.14
Nukiwa, T.15
Stine, O.C.16
Abraham, J.M.17
Shibata, D.18
Meltzer, S.J.19
-
77
-
-
77649164867
-
Evolutionary gain of function of the ER membrane protein Sec62 from yeast to humans
-
Müller L, Diaz de Escauriaza M, Lajoie P, Theis M, Jung M, Müller A, Burgard C, Greiner M, Snapp EL, Dudek J, Zimmermann R (2010) Evolutionary gain of function of the ER membrane protein Sec62 from yeast to humans. Mol Biol Cell 21:691–703
-
(2010)
Mol Biol Cell
, vol.21
, pp. 691-703
-
-
Müller, L.1
De Diaz Escauriaza, M.2
Lajoie, P.3
Theis, M.4
Jung, M.5
Müller, A.6
Burgard, C.7
Greiner, M.8
Snapp, E.L.9
Dudek, J.10
Zimmermann, R.11
-
78
-
-
0023052239
-
An Hsp70-like protein in the ER: Identity with the 78 kd glucoseregulated protein and immunoglobulin heavy chain binding protein
-
Munro S, Pelham HRB (1986) An Hsp70-like protein in the ER: identity with the 78 kd glucoseregulated protein and immunoglobulin heavy chain binding protein. Cell 46:291–300
-
(1986)
Cell
, vol.46
, pp. 291-300
-
-
Munro, S.1
Pelham, H.2
-
79
-
-
0027238583
-
Lumenal proteins of the mammalian endoplasmic reticulum are required to complete protein translocation
-
Nicchitta CV, Blobel G (1993) Lumenal proteins of the mammalian endoplasmic reticulum are required to complete protein translocation. Cell 73:989–998
-
(1993)
Cell
, vol.73
, pp. 989-998
-
-
Nicchitta, C.V.1
Blobel, G.2
-
80
-
-
0038576294
-
Cloning and Characterization of a novel GRP78-binding protein in the rat brain
-
Oh-hashi K, Naruse Y, Amaya F, Shimosato G, Tanaka M (2003) Cloning and Characterization of a novel GRP78-binding protein in the rat brain. J Biol Chem 278:10531–10537
-
(2003)
J Biol Chem
, vol.278
, pp. 10531-10537
-
-
Oh-Hashi, K.1
Naruse, Y.2
Amaya, F.3
Shimosato, G.4
Tanaka, M.5
-
81
-
-
84880819436
-
ERdj5 is the ER reductase that catalyzes the removal of non-native disulfides and correct folding of the LDL receptor
-
Oka OBV, Pringle MA, Schopp IM, Braakman I, Bulleid NJ (2013) ERdj5 is the ER reductase that catalyzes the removal of non-native disulfides and correct folding of the LDL receptor. Mol Cell 50:793–804
-
(2013)
Mol Cell
, vol.50
, pp. 793-804
-
-
Oka, O.1
Pringle, M.A.2
Schopp, I.M.3
Braakman, I.4
Bulleid, N.J.5
-
83
-
-
33847136350
-
Intracellular Ca2+ release via the ER translocon activates store-operated calcium entry
-
Ong HL, Liu X, Sharma A, Hegde RS, Ambudkar IS (2007) Intracellular Ca2+ release via the ER translocon activates store-operated calcium entry. Pflugers Arch 453:797–808
-
(2007)
Pflugers Arch
, vol.453
, pp. 797-808
-
-
Ong, H.L.1
Liu, X.2
Sharma, A.3
Hegde, R.S.4
Ambudkar, I.S.5
-
84
-
-
0016785996
-
Intracellular aspects of protein synthesis
-
Palade G (1975) Intracellular aspects of protein synthesis. Science 189:347–358
-
(1975)
Science
, vol.189
, pp. 347-358
-
-
Palade, G.1
-
85
-
-
33749522548
-
AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP
-
Paton AW, Beddoe T, Thorpe CM, Whisstock JC, Wilche MC, Rossjohn J, Talbot UM, Paton JC (2006) AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP. Nature 443:548–552
-
(2006)
Nature
, vol.443
, pp. 548-552
-
-
Paton, A.W.1
Beddoe, T.2
Thorpe, C.M.3
Whisstock, J.C.4
Wilche, M.C.5
Rossjohn, J.6
Talbot, U.M.7
Paton, J.C.8
-
86
-
-
0025225456
-
The retention signal for soluble proteins of the endoplasmic reticulum
-
Pelham HRB (1990) The retention signal for soluble proteins of the endoplasmic reticulum. Trends Biochem Sci 15:483–486
-
(1990)
Trends Biochem Sci
, vol.15
, pp. 483-486
-
-
Pelham, H.1
-
87
-
-
69149090973
-
Common design principles in the spliceosomal RNA helicase Brr2 and in the Hel308 DNA helicase
-
Pena V, Jovin SM, Fabrizio P, Orlowski J, Bujnicki JM, Lührmann R, Wahl MC (2009) Common design principles in the spliceosomal RNA helicase Brr2 and in the Hel308 DNA helicase. Mol Cell 35:454–466
-
(2009)
Mol Cell
, vol.35
, pp. 454-466
-
-
Pena, V.1
Jovin, S.M.2
Fabrizio, P.3
Orlowski, J.4
Bujnicki, J.M.5
Lührmann, R.6
Wahl, M.C.7
-
88
-
-
55549141494
-
Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3
-
Petrova K, Oyadomari S, Hendershot LM, Ron D (2008) Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3. EMBO J 27:2862–2872
-
(2008)
EMBO J
, vol.27
, pp. 2862-2872
-
-
Petrova, K.1
Oyadomari, S.2
Hendershot, L.M.3
Ron, D.4
-
89
-
-
84865781069
-
Structure and 3D arrangement of ER-membrane associated ribosomes
-
Pfeffer S, Brandt F, Hrabe T, Lang S, Eibauer M, Zimmermann R, Förster F (2012) Structure and 3D arrangement of ER-membrane associated ribosomes. Structure 20:1508–1518
-
(2012)
Structure
, vol.20
, pp. 1508-1518
-
-
Pfeffer, S.1
Brandt, F.2
Hrabe, T.3
Lang, S.4
Eibauer, M.5
Zimmermann, R.6
Förster, F.7
-
90
-
-
84892141124
-
Structure of the mammalian oligosaccharyl-transferase in the native ER protein translocon
-
Pfeffer S, Dudek J, Gogala M, Schorr S, Linxweiler J, Lang S, Becker T, Beckmann R, Zimmermann R, Förster F (2014) Structure of the mammalian oligosaccharyl-transferase in the native ER protein translocon. Nature Comm. doi:10.1038/ncomms4072
-
(2014)
Nature Comm
-
-
Pfeffer, S.1
Dudek, J.2
Gogala, M.3
Schorr, S.4
Linxweiler, J.5
Lang, S.6
Becker, T.7
Beckmann, R.8
Zimmermann, R.9
Förster, F.10
-
91
-
-
0030789680
-
Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation
-
Pilon M, Schekman R, Römisch K (1997) Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation. EMBO J 16:4540–4548
-
(1997)
EMBO J
, vol.16
, pp. 4540-4548
-
-
Pilon, M.1
Schekman, R.2
Römisch, K.3
-
92
-
-
1842409617
-
Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation
-
Plemper RK, Böhmler S, Bordallo J, Sommer T, Wolf DH (1997) Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation. Nature 388:891–895
-
(1997)
Nature
, vol.388
, pp. 891-895
-
-
Plemper, R.K.1
Böhmler, S.2
Bordallo, J.3
Sommer, T.4
Wolf, D.H.5
-
93
-
-
44649110104
-
Structural basis for the cooperation of Hsp70 and Hsp110 chaperones in protein folding
-
Polier S, Dragovic Z, Hartl FU, Bracher, A (2008) Structural basis for the cooperation of Hsp70 and Hsp110 chaperones in protein folding. Cell 133:1068–1079
-
(2008)
Cell
, vol.133
, pp. 1068-1079
-
-
Polier, S.1
Dragovic, Z.2
Hartl, F.U.3
Bracher, A.4
-
94
-
-
33644847375
-
Microdomains of intracellular Ca2+: Molecular determinants and functional consequences
-
Rizzuto R, Pozzan T (2006) Microdomains of intracellular Ca2+: molecular determinants and functional consequences. Physiol Rev 86:369–408
-
(2006)
Physiol Rev
, vol.86
, pp. 369-408
-
-
Rizzuto, R.1
Pozzan, T.2
-
95
-
-
84870732594
-
Protein-folding homeostasis in the endoplasmic reticulum and nutritional regulation
-
Ron D, Harding HP (2012) Protein-folding homeostasis in the endoplasmic reticulum and nutritional regulation. Cold Spring Harb Perspect Biol 4:a013177
-
(2012)
Cold Spring Harb Perspect Biol
, vol.4
-
-
Ron, D.1
Harding, H.P.2
-
96
-
-
84899970002
-
Severe degenerative myopathy in woozy mice: Chaperonopathy and specific nuclear envelope pathology due to Sil1 dysfuction in a model for Marinesco-Sjögren syndrome
-
Roos A, Buchlremer S, Labisch T, Gatz C, Brauers E, Nolte K, Goebel HH, Zimmermann R, Senderek J, Weis J (2014) Severe degenerative myopathy in woozy mice: chaperonopathy and specific nuclear envelope pathology due to Sil1 dysfuction in a model for Marinesco-Sjögren syndrome. Acta Neuropathologica 127:761–777
-
(2014)
Acta Neuropathologica
, vol.127
, pp. 761-777
-
-
Roos, A.1
Buchlremer, S.2
Labisch, T.3
Gatz, C.4
Brauers, E.5
Nolte, K.6
Goebel, H.H.7
Zimmermann, R.8
Senderek, J.9
Weis, J.10
-
97
-
-
34548512233
-
The role of p58IPK in protecting the stressed endoplasmic reticulum
-
Rutkowski DT, Kang SW, Goodman AG, Garrison JL, Taunton J, Katze MG, Kaufman RJ, Hedge RS (2007) The role of p58IPK in protecting the stressed endoplasmic reticulum. Mol Biol Cell 18:3681–3691
-
(2007)
Mol Biol Cell
, vol.18
, pp. 3681-3691
-
-
Rutkowski, D.T.1
Kang, S.W.2
Goodman, A.G.3
Garrison, J.L.4
Taunton, J.5
Katze, M.G.6
Kaufman, R.J.7
Hedge, R.S.8
-
98
-
-
0025361036
-
The involvement of calcium in transport of secretory proteins from the endoplasmic reticulum
-
Sambrook JF (1990) The involvement of calcium in transport of secretory proteins from the endoplasmic reticulum. Cell 61:197–199
-
(1990)
Cell
, vol.61
, pp. 197-199
-
-
Sambrook, J.F.1
-
99
-
-
70350564161
-
Sec61p is part of the endoplasmic reticulum-associated degradation machinery
-
Schäfer A, Wolf DH (2009) Sec61p is part of the endoplasmic reticulum-associated degradation machinery. EMBO J 28:2874–2884
-
(2009)
EMBO J
, vol.28
, pp. 2874-2884
-
-
Schäfer, A.1
Wolf, D.H.2
-
100
-
-
84864877220
-
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER
-
Schäuble N, Lang S, Jung M, Cappel S, Schorr S, Ulucan Ö, Linxweiler J, Dudek J, Blum R, Helms V, Paton A W, Paton J C, Cavalié A, Zimmermann R (2012) BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER. EMBO J 31:3282–3296
-
(2012)
EMBO J
, vol.31
, pp. 3282-3296
-
-
Schäuble, N.1
Lang, S.2
Jung, M.3
Cappel, S.4
Schorr, S.5
Ulucan, Ö.6
Linxweiler, J.7
Dudek, J.8
Blum, R.9
Helms, V.10
Paton, A.W.11
Paton, J.C.12
Cavalié, A.13
Zimmermann, R.14
-
101
-
-
2942735001
-
Merging cultures in the study of membrane traffic
-
Schekman R (2004) Merging cultures in the study of membrane traffic. Nature Cell Biol 6:483–486
-
(2004)
Nature Cell Biol
, vol.6
, pp. 483-486
-
-
Schekman, R.1
-
102
-
-
22144434043
-
Peroxisomes: Another branch of the secretory pathway?
-
Schekman R (2005) Peroxisomes: Another branch of the secretory pathway? Cell 122:1–7
-
(2005)
Cell
, vol.122
, pp. 1-7
-
-
Schekman, R.1
-
103
-
-
79952364237
-
Mechanics of Hsp70 chaperones enables differential interaction with client proteins
-
Schlecht R, Erbse AH, Bukau B, Mayer MP (2011) Mechanics of Hsp70 chaperones enables differential interaction with client proteins. Nat Struct Mol Biol 18:345–351
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 345-351
-
-
Schlecht, R.1
Erbse, A.H.2
Bukau, B.3
Mayer, M.P.4
-
104
-
-
20244387702
-
HNPCC-associated small bowel cancer: Clinical and molecular characteristics
-
Schulmann K, Brasch FE, Kunstmann E, Engel C, Pagenstecher C, Vogelsang H, Krüger S, Vogel T, Knaebel H-P, Rüschoff J, Hahn SA, von Knebel-Doeberitz M, Moeslein G, Meltzer SJ, Schackert HK, Tympner C, Mangold E, Schmiegel W for the German HNPCC consortium (2005) HNPCC-associated small bowel cancer: Clinical and molecular characteristics. Gastroenterol 128:590–599
-
(2005)
Gastroenterol
, vol.128
, pp. 590-599
-
-
Schulmann, K.1
Brasch, F.E.2
Kunstmann, E.3
Engel, C.4
Pagenstecher, C.5
Vogelsang, H.6
Krüger, S.7
Vogel, T.8
Knaebel, H.-P.9
Rüschoff, J.10
Hahn, S.A.11
Von Knebel-Doeberitz, M.12
Moeslein, G.13
Meltzer, S.J.14
Schackert, H.K.15
Tympner, C.16
Mangold, E.17
Schmiegel, W.18
-
105
-
-
28444497039
-
Mutations in Sil1 cause Marinesco-Sjögren syndrome, a cerebellar ataxia with cataract and myopathy
-
Senderek J, Krieger M, Stendel C, Bergmann C, Moser M, Breitbach-Faller N, Rudinik-Schoneborn S, Blaschek A, Wolf N, Harting I, North K, Smith J, Muntoni F, Brockington M, Quijano-Roy S, Renault F, Herrmann R, Hendeshot LM, Schröder JM, Lochmüller H, Topaloglu H, Voit T, Weis J, Ebinger F, Zerres K (2005) Mutations in Sil1 cause Marinesco-Sjögren syndrome, a cerebellar ataxia with cataract and myopathy. Nat Gen 37:1312–1314
-
(2005)
Nat Gen
, vol.37
, pp. 1312-1314
-
-
Senderek, J.1
Krieger, M.2
Stendel, C.3
Bergmann, C.4
Moser, M.5
Breitbach-Faller, N.6
Rudinik-Schoneborn, S.7
Blaschek, A.8
Wolf, N.9
Harting, I.10
North, K.11
Smith, J.12
Muntoni, F.13
Brockington, M.14
Quijano-Roy, S.15
Renault, F.16
Herrmann, R.17
Hendeshot, L.M.18
Schröder, J.M.19
Lochmüller, H.20
Topaloglu, H.21
Voit, T.22
Weis, J.23
Ebinger, F.24
Zerres, K.25
more..
-
106
-
-
26444571807
-
Regulation of protein compartmentalization expands the diversity of protein function
-
Shaffer KL, Sharma A, Snapp EL, Hegde RS (2005) Regulation of protein compartmentalization expands the diversity of protein function. Dev Cell 9:545–554
-
(2005)
Dev Cell
, vol.9
, pp. 545-554
-
-
Shaffer, K.L.1
Sharma, A.2
Snapp, E.L.3
Hegde, R.S.4
-
107
-
-
11144249887
-
ERdj3p, a stress-inducible endoplasmic reticulum DnaJ homologue, serves as a cofactor for BiP's interactions with unfolded substrates
-
Shen Y, Hendershot LM (2005) ERdj3p, a stress-inducible endoplasmic reticulum DnaJ homologue, serves as a cofactor for BiP's interactions with unfolded substrates. Mol Biol Cell 16:40–50
-
(2005)
Mol Biol Cell
, vol.16
, pp. 40-50
-
-
Shen, Y.1
Hendershot, L.M.2
-
108
-
-
0037013252
-
Identification and characterization of a novel endoplasmic reticulum (ER) DnaJ homologue, which stimulates ATPase activity of BiP in vitro and is induced by ER stress
-
Shen Y, Meunier L, Hendershot LM (2002) Identification and characterization of a novel endoplasmic reticulum (ER) DnaJ homologue, which stimulates ATPase activity of BiP in vitro and is induced by ER stress. J Biol Chem 277:15947–15956
-
(2002)
J Biol Chem
, vol.277
, pp. 15947-15956
-
-
Shen, Y.1
Meunier, L.2
Hendershot, L.M.3
-
109
-
-
0031755020
-
Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control
-
Shi Y, Vattem K M, Sood R, An J, Liang J, Stramm L, Wek RC (1998) Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control. Mol Cell Biol 18:7499–7509
-
(1998)
Mol Cell Biol
, vol.18
, pp. 7499-7509
-
-
Shi, Y.1
Vattem, K.M.2
Sood, R.3
An, J.4
Liang, J.5
Stramm, L.6
Wek, R.C.7
-
110
-
-
0010625474
-
Glucose depletion accounts for the induction of two transformation-sensitive membrane proteins in Rous sarcoma virus-transformed chick embryo fibrobalsts
-
Shiu RP, Pouyssegur J, Pasta I (1977) Glucose depletion accounts for the induction of two transformation-sensitive membrane proteins in Rous sarcoma virus-transformed chick embryo fibrobalsts. Proc Natl Acad Sci U S A 74:3840–3844
-
(1977)
Proc Natl Acad Sci U S A
, vol.74
, pp. 3840-3844
-
-
Shiu, R.P.1
Pouyssegur, J.2
Pasta, I.3
-
111
-
-
13244278043
-
Regulation of Hsp70 function by HspBP1: Structural analysis reveals an alternate mechanism for Hsp70 nucleotide exchange
-
Shomura Y, Dragovic Z, Chang HC, Tzvetkov N, Young JC, Brodsky JL, Guerriero V, Hartl FU, Bracher A (2005) Regulation of Hsp70 function by HspBP1: structural analysis reveals an alternate mechanism for Hsp70 nucleotide exchange. Mol Cell 17:367–379
-
(2005)
Mol Cell
, vol.17
, pp. 367-379
-
-
Shomura, Y.1
Dragovic, Z.2
Chang, H.C.3
Tzvetkov, N.4
Young, J.C.5
Brodsky, J.L.6
Guerriero, V.7
Hartl, F.U.8
Bracher, A.9
-
112
-
-
0032871620
-
Molecular characterization of a novel mammalian DnaJ-like Sec63p homolog
-
Skowronek MH, Rotter M, Haas IG (1999) Molecular characterization of a novel mammalian DnaJ-like Sec63p homolog. Biol Chem 380:1133–1138
-
(1999)
Biol Chem
, vol.380
, pp. 1133-1138
-
-
Skowronek, M.H.1
Rotter, M.2
Haas, I.G.3
-
113
-
-
82255161944
-
Road to ruin: Targeting proteins for degradation in the endoplasmic reticulum
-
Smith MH, Ploegh HL, Weissman JS (2011) Road to ruin: targeting proteins for degradation in the endoplasmic reticulum. Science 334:1086–1090
-
(2011)
Science
, vol.334
, pp. 1086-1090
-
-
Smith, M.H.1
Ploegh, H.L.2
Weissman, J.S.3
-
115
-
-
79952264011
-
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
-
Tabas I, Ron D (2011) Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress. Nature Cell Biol 13:184–190
-
(2011)
Nature Cell Biol
, vol.13
, pp. 184-190
-
-
Tabas, I.1
Ron, D.2
-
116
-
-
0031045007
-
Interactions between newly synthesized glycoproteins, calnexin and a network of resident chaperones in the endoplasmic reticulum
-
Tatu U, Helenius A (1997) Interactions between newly synthesized glycoproteins, calnexin and a network of resident chaperones in the endoplasmic reticulum. J Cell Biol 136:555–565
-
(1997)
J Cell Biol
, vol.136
, pp. 555-565
-
-
Tatu, U.1
Helenius, A.2
-
118
-
-
0032525990
-
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinas/endoribonuclease(Ire1p) in mammalian cells
-
Tirasophon W, Welihinda AA, Kaufman RJ (1998) A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinas/endoribonuclease(Ire1p) in mammalian cells. Genes Develop 12:1812–1824
-
(1998)
Genes Develop
, vol.12
, pp. 1812-1824
-
-
Tirasophon, W.1
Welihinda, A.A.2
Kaufman, R.J.3
-
119
-
-
12944254591
-
Homologs of the yeast Sec complex subunits Sec62p and Sec63p are abundant proteins in dog pancreas microsomes
-
Tyedmers J, Lerner M, Bies C, Dudek J, Skowronek MH, Haas IG, Heim N, Nastainczyk W, Volkmer J, Zimmermann R (2000) Homologs of the yeast Sec complex subunits Sec62p and Sec63p are abundant proteins in dog pancreas microsomes. Proc Natl Acad Sci U S A 97:7214–7219
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 7214-7219
-
-
Tyedmers, J.1
Lerner, M.2
Bies, C.3
Dudek, J.4
Skowronek, M.H.5
Haas, I.G.6
Heim, N.7
Nastainczyk, W.8
Volkmer, J.9
Zimmermann, R.10
-
120
-
-
0038786906
-
Polypeptide chain binding proteins mediate completion of cotranslational protein translocation into the mammalian endoplasmic reticulum
-
Tyedmers J, Lerner M, Wiedmann M, Volkmer J, Zimmermann R (2003) Polypeptide chain binding proteins mediate completion of cotranslational protein translocation into the mammalian endoplasmic reticulum. EMBO Rep 4:505–510
-
(2003)
EMBO Rep
, vol.4
, pp. 505-510
-
-
Tyedmers, J.1
Lerner, M.2
Wiedmann, M.3
Volkmer, J.4
Zimmermann, R.5
-
121
-
-
48249117110
-
ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER
-
Ushioda R, Hoseki J, Araki K, Jansen G, Thomas DY, Nagata K (2008) ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER. Science 321:569–572
-
(2008)
Science
, vol.321
, pp. 569-572
-
-
Ushioda, R.1
Hoseki, J.2
Araki, K.3
Jansen, G.4
Thomas, D.Y.5
Nagata, K.6
-
122
-
-
0024326031
-
Four intracisternal calcium-binding glycoproteins from rat liver microsomes with high affinity for calcium
-
Van PN, Peter F, Söling H-D (1989) Four intracisternal calcium-binding glycoproteins from rat liver microsomes with high affinity for calcium. J Biol Chem 264:17494–17501
-
(1989)
J Biol Chem
, vol.264
, pp. 17494-17501
-
-
Van, P.N.1
Peter, F.2
Söling, H.-D.3
-
123
-
-
4444234264
-
Ribosome-translocon complex mediates calcium leakage from endoplasmic reticulum stores
-
Van Coppenolle F, Vanden Abeele F, Slomianny C, Flourakis M, Hesketh J, Dewailly E, Prevarskaya N (2004) Ribosome-translocon complex mediates calcium leakage from endoplasmic reticulum stores. J Cell Sci 117:4135–4142
-
(2004)
J Cell Sci
, vol.117
, pp. 4135-4142
-
-
Van Coppenolle, F.1
Vanden Abeele, F.2
Slomianny, C.3
Flourakis, M.4
Hesketh, J.5
Dewailly, E.6
Prevarskaya, N.7
-
124
-
-
0347192985
-
X-ray structure of a protein-conducting channel
-
van den Berg B, Clemons WM, Collinson I, Modis Y, Hartmann E, Harrison SC, Rapoport TA (2004) X-ray structure of a protein-conducting channel. Nature 427:36–44
-
(2004)
Nature
, vol.427
, pp. 36-44
-
-
Van Den Berg, B.1
Clemons, W.M.2
Collinson, I.3
Modis, Y.4
Hartmann, E.5
Harrison, S.C.6
Rapoport, T.A.7
-
125
-
-
14944361914
-
Protein kinase CK2 phosphorylates Sec63p to stimulate the assembly of the endoplasmic reticulum protein translocation apparatus
-
Wang X, Johnsson N (2005) Protein kinase CK2 phosphorylates Sec63p to stimulate the assembly of the endoplasmic reticulum protein translocation apparatus. J Cell Sci 118:723–732
-
(2005)
J Cell Sci
, vol.118
, pp. 723-732
-
-
Wang, X.1
Johnsson, N.2
-
126
-
-
0032190546
-
Cloning of mammalian Ire1 reveals diversity in the ER stress response
-
Wang XZ, Harding HP, Zhang Y, Jolicoeur EM, Kuroda M, Ron D (1998) Cloning of mammalian Ire1 reveals diversity in the ER stress response. EMBO J 17:5708–5717
-
(1998)
EMBO J
, vol.17
, pp. 5708-5717
-
-
Wang, X.Z.1
Harding, H.P.2
Zhang, Y.3
Jolicoeur, E.M.4
Kuroda, M.5
Ron, D.6
-
127
-
-
33748776034
-
The nucleotide exchange factor activity of Grp170 may explain the non-lethal phenotype of loss of Sil1 function in man and mouse
-
Weitzmann A, Volkmer J, Zimmermann R (2006) The nucleotide exchange factor activity of Grp170 may explain the non-lethal phenotype of loss of Sil1 function in man and mouse. FEBS Lett 580:5237–5240
-
(2006)
FEBS Lett
, vol.580
, pp. 5237-5240
-
-
Weitzmann, A.1
Volkmer, J.2
Zimmermann, R.3
-
128
-
-
34748918368
-
The heat shock protein 70 molecular chaperone network in the pancreatic endoplasmic reticulum—a quantitative approach
-
Weitzmann A, Baldes C, Dudek J, Zimmermann R (2007) The heat shock protein 70 molecular chaperone network in the pancreatic endoplasmic reticulum—a quantitative approach. FEBS J 274:5175–5187
-
(2007)
FEBS J
, vol.274
, pp. 5175-5187
-
-
Weitzmann, A.1
Baldes, C.2
Dudek, J.3
Zimmermann, R.4
-
130
-
-
0032509216
-
XBP1 Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional iduction of mammalian glucose-regulated proteins: Involvement of basic-leucine zipper transcription factors
-
Yoshida H, Haze K, Yanagi H, Yura T, Mori K (1998) XBP1 Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional iduction of mammalian glucose-regulated proteins: involvement of basic-leucine zipper transcription factors. J Biol Chem 273:33741–33749
-
(1998)
J Biol Chem
, vol.273
, pp. 33741-33749
-
-
Yoshida, H.1
Haze, K.2
Yanagi, H.3
Yura, T.4
Mori, K.5
-
131
-
-
0034637459
-
HEDJ, an Hsp40 Co-chaperone localized to the endoplasmic reticulum of human cells
-
Yu M, Haslam RHA, Haslam DB (2000) HEDJ, an Hsp40 Co-chaperone localized to the endoplasmic reticulum of human cells. J Biol Chem 275:24984–24992
-
(2000)
J Biol Chem
, vol.275
, pp. 24984-24992
-
-
Yu, M.1
Haslam, R.2
Haslam, D.B.3
-
132
-
-
67651211597
-
Analysis of the membrane proteome of canine pancreatic rough microsomes identifies a novel Hsp40, termed ERj7
-
Zahedi RP, Völzing C, Schmitt A, Frien M, Jung M, Dudek J, Wortelkamp S, Sickmann A, Zimmermann R (2009) Analysis of the membrane proteome of canine pancreatic rough microsomes identifies a novel Hsp40, termed ERj7. Proteomics 9:3463–3473
-
(2009)
Proteomics
, vol.9
, pp. 3463-3473
-
-
Zahedi, R.P.1
Völzing, C.2
Schmitt, A.3
Frien, M.4
Jung, M.5
Dudek, J.6
Wortelkamp, S.7
Sickmann, A.8
Zimmermann, R.9
-
133
-
-
25144520251
-
Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP
-
Zhao L, Longo-Guess C, Harris BS, Lee JW, Ackerman SL (2005) Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP. Nat Genet 37:974–979
-
(2005)
Nat Genet
, vol.37
, pp. 974-979
-
-
Zhao, L.1
Longo-Guess, C.2
Harris, B.S.3
Lee, J.W.4
Ackerman, S.L.5
-
134
-
-
77649314881
-
Alteration of the unfolded protein response modifies neurodegeneration in a mouse model of Marinesco-Sjögren syndrome
-
Zhao L, Rosales C, Seburn K, Ron D, Ackerman S L (2010) Alteration of the unfolded protein response modifies neurodegeneration in a mouse model of Marinesco-Sjögren syndrome. Human Mol Gen 19:25–35
-
(2010)
Human Mol Gen
, vol.19
, pp. 25-35
-
-
Zhao, L.1
Rosales, C.2
Seburn, K.3
Ron, D.4
Ackerman, S.L.5
-
136
-
-
0035751187
-
Computational prediction of membrane-tethered transcription factors
-
Zupicich J, Brenner SE, Skarnes WC (2001) Computational prediction of membrane-tethered transcription factors. Genome Biol 2:501–506
-
(2001)
Genome Biol
, vol.2
, pp. 501-506
-
-
Zupicich, J.1
Brenner, S.E.2
Skarnes, W.C.3
|