-
1
-
-
8844230242
-
The protein-conducting channel SecYEG
-
Veenendaal, A. K. J., van der Does, C., and Driessen, A. J. M. (2004) The protein-conducting channel SecYEG, Biochim. Biophys. Acta 1694, 81-95.
-
(2004)
Biochim. Biophys. Acta
, vol.1694
, pp. 81-95
-
-
Veenendaal, A.K.J.1
van der Does, C.2
Driessen, A.J.M.3
-
2
-
-
27844485836
-
Protein translocation by the Sec61/SecY channel
-
Osborne, A. R., Rapoport, T. A., and van den Berg, B. (2005) Protein translocation by the Sec61/SecY channel, Annu. Rev. Cell Dev. Biol. 21, 529-550.
-
(2005)
Annu. Rev. Cell Dev. Biol
, vol.21
, pp. 529-550
-
-
Osborne, A.R.1
Rapoport, T.A.2
van den Berg, B.3
-
3
-
-
27144454336
-
Diversity and evolution of protein translocation
-
Pohlschröder, M., Hartmann, E., Hand, N. J., Dilks, K., and Haddad, A. (2005) Diversity and evolution of protein translocation, Annu. Rev. Microbiol. 59, 91-111.
-
(2005)
Annu. Rev. Microbiol
, vol.59
, pp. 91-111
-
-
Pohlschröder, M.1
Hartmann, E.2
Hand, N.J.3
Dilks, K.4
Haddad, A.5
-
4
-
-
28544442609
-
Protein translocation across biological membranes
-
Wickner, W., and Schekman, R. (2005) Protein translocation across biological membranes, Science 310, 1452-1456.
-
(2005)
Science
, vol.310
, pp. 1452-1456
-
-
Wickner, W.1
Schekman, R.2
-
5
-
-
27144463438
-
Biogenesis of inner membrane proteins in Escherichia coli
-
Luirink, J., von Heijne, G., Houben, E., and de Gier, J.-W. (2005) Biogenesis of inner membrane proteins in Escherichia coli, Annu. Rev. Microbiol. 59, 329-355.
-
(2005)
Annu. Rev. Microbiol
, vol.59
, pp. 329-355
-
-
Luirink, J.1
von Heijne, G.2
Houben, E.3
de Gier, J.-W.4
-
6
-
-
33745218504
-
Protein secretion in the Archaea: Multiple paths towards a unique cell surface
-
Albers, S.-V., Szabó, Z., and Driessen, A. J. M. (2006) Protein secretion in the Archaea: Multiple paths towards a unique cell surface, Nat. Rev. Microbiol. 4, 537-547.
-
(2006)
Nat. Rev. Microbiol
, vol.4
, pp. 537-547
-
-
Albers, S.-V.1
Szabó, Z.2
Driessen, A.J.M.3
-
7
-
-
0032488845
-
Protein translocation: Tunnel vision
-
Matlack, K. E. S., Mothes, W., and Rapoport, T. A. (1998) Protein translocation: Tunnel vision, Cell 92, 381-390.
-
(1998)
Cell
, vol.92
, pp. 381-390
-
-
Matlack, K.E.S.1
Mothes, W.2
Rapoport, T.A.3
-
8
-
-
0347192985
-
X-ray structure of a protein-conducting channel
-
van den Berg, B., Clemons, W. M., Jr., Collinson, I., Modis, Y., Hartmann, E., Harrison, S. C., and Rapoport, T. A. (2004) X-ray structure of a protein-conducting channel, Nature 427, 36-44.
-
(2004)
Nature
, vol.427
, pp. 36-44
-
-
van den Berg, B.1
Clemons Jr., W.M.2
Collinson, I.3
Modis, Y.4
Hartmann, E.5
Harrison, S.C.6
Rapoport, T.A.7
-
9
-
-
18544380083
-
Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY
-
Cannon, K. S., Or, E., Clemons, W. M., Jr., Shibata, Y., and Rapoport, T. A. (2005) Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY, J. Cell Biol. 169, 219-225.
-
(2005)
J. Cell Biol
, vol.169
, pp. 219-225
-
-
Cannon, K.S.1
Or, E.2
Clemons Jr., W.M.3
Shibata, Y.4
Rapoport, T.A.5
-
10
-
-
33646271115
-
Molecular dynamics studies of the archaeal translocon
-
Gumbart, J., and Schulten, K. (2006) Molecular dynamics studies of the archaeal translocon, Biophys. J. 90, 2356-2367.
-
(2006)
Biophys. J
, vol.90
, pp. 2356-2367
-
-
Gumbart, J.1
Schulten, K.2
-
11
-
-
33748300566
-
-
ll.Junne, T., Schwede, T., Goder, V., and Spiess, M. (2006) The plug domain of yeast Sec61p is important for efficient protein translocation, but is not essential for cell viability, Mol. Biol. Cell 17, 4063-4068.
-
ll.Junne, T., Schwede, T., Goder, V., and Spiess, M. (2006) The plug domain of yeast Sec61p is important for efficient protein translocation, but is not essential for cell viability, Mol. Biol. Cell 17, 4063-4068.
-
-
-
-
12
-
-
13444262028
-
Recognition of transmembrane helices by the endoplasmic reticulum translocon
-
Hessa, T., Kim, H., Bihlmaier, K., Lundin, C., Boekel, J., Andersson, H., Nilsson, I., White, S. H., and von Heijne, G. (2005) Recognition of transmembrane helices by the endoplasmic reticulum translocon, Nature 433, 377-381.
-
(2005)
Nature
, vol.433
, pp. 377-381
-
-
Hessa, T.1
Kim, H.2
Bihlmaier, K.3
Lundin, C.4
Boekel, J.5
Andersson, H.6
Nilsson, I.7
White, S.H.8
von Heijne, G.9
-
13
-
-
23044510444
-
Transmembrane helices before, during, and after insertion
-
White, S. H., and von Heijne, G. (2005) Transmembrane helices before, during, and after insertion, Curr. Opin. Struct. Biol. 15, 378-386.
-
(2005)
Curr. Opin. Struct. Biol
, vol.15
, pp. 378-386
-
-
White, S.H.1
von Heijne, G.2
-
14
-
-
33645984562
-
Has the code for protein translocation been broken?
-
Shental-Bechor, D., Fleishman, S. J., and Ben-Tal, N. (2006) Has the code for protein translocation been broken? Trends Biochem. Sei. 31, 192-196.
-
(2006)
Trends Biochem. Sei
, vol.31
, pp. 192-196
-
-
Shental-Bechor, D.1
Fleishman, S.J.2
Ben-Tal, N.3
-
15
-
-
0030825974
-
Molecular mechanism of membrane protein integration into the endoplasmic reticulum
-
Mothes, W., Heinrich, S. U., Graf, R., Nilsson, I., von Heijne, G., Brunner, J., and Rapoport, T. A. (1997) Molecular mechanism of membrane protein integration into the endoplasmic reticulum, Cell 89, 523-533.
-
(1997)
Cell
, vol.89
, pp. 523-533
-
-
Mothes, W.1
Heinrich, S.U.2
Graf, R.3
Nilsson, I.4
von Heijne, G.5
Brunner, J.6
Rapoport, T.A.7
-
16
-
-
27144549973
-
Sequential triage of transmembrane segments by Sec61α during biogenesis of a native multispanning membrane protein
-
Sadlish, H., Pitonzo, D., Johnson, A. E., and Skach, W. R. (2005) Sequential triage of transmembrane segments by Sec61α during biogenesis of a native multispanning membrane protein, Nat. Struct. Mol. Biol. 10, 870-878.
-
(2005)
Nat. Struct. Mol. Biol
, vol.10
, pp. 870-878
-
-
Sadlish, H.1
Pitonzo, D.2
Johnson, A.E.3
Skach, W.R.4
-
17
-
-
33746923016
-
Active and passive displacement of transmembrane domains both occur during opsin biogenesis at the Sec61 translocon
-
Ismail, N., Crawshaw, S. G., and High, S. (2006) Active and passive displacement of transmembrane domains both occur during opsin biogenesis at the Sec61 translocon, J. Cell Sci. 119, 2826-2836.
-
(2006)
J. Cell Sci
, vol.119
, pp. 2826-2836
-
-
Ismail, N.1
Crawshaw, S.G.2
High, S.3
-
18
-
-
34347249218
-
+ channel voltage sensor domain
-
+ channel voltage sensor domain, Proc. Natl. Acad. Sci. U.S.A. 104, 8263-8268.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A
, vol.104
, pp. 8263-8268
-
-
Zhang, L.1
Sato, Y.2
Hessa, T.3
von Heijne, G.4
Lee, J.-K.5
Kodama, I.6
Sakaguchi, M.7
Uozumi, N.8
-
19
-
-
0034616309
-
Unfolding pathways of individual bacteriorhodopsins
-
Oesterhelt, F., Oesterhelt, D., Pfeiffer, M., Engel, A., Gaub, H. E., and Müller, D. J. (2000) Unfolding pathways of individual bacteriorhodopsins, Science 288, 143-146.
-
(2000)
Science
, vol.288
, pp. 143-146
-
-
Oesterhelt, F.1
Oesterhelt, D.2
Pfeiffer, M.3
Engel, A.4
Gaub, H.E.5
Müller, D.J.6
-
20
-
-
2342646040
-
Probing the energy landscape of the membrane protein bacteriorhodopsin
-
Janovjak, H., Struckmeier, J., Hubain, M., Kedrov, A., Kessler, M., and Müller, D. J. (2004) Probing the energy landscape of the membrane protein bacteriorhodopsin, Structure 12, 871-879.
-
(2004)
Structure
, vol.12
, pp. 871-879
-
-
Janovjak, H.1
Struckmeier, J.2
Hubain, M.3
Kedrov, A.4
Kessler, M.5
Müller, D.J.6
-
21
-
-
0037043724
-
Three-dimensional structure of the bacterial protein-translocation complex SecYEG
-
Breyton, C., Haase, W., Rapoport, T. A., Kühlbrandt, W., and Collinson, I. (2002) Three-dimensional structure of the bacterial protein-translocation complex SecYEG, Nature 418, 662-665.
-
(2002)
Nature
, vol.418
, pp. 662-665
-
-
Breyton, C.1
Haase, W.2
Rapoport, T.A.3
Kühlbrandt, W.4
Collinson, I.5
-
22
-
-
0036500974
-
The SecYEG preprotein translocation channel is a conformationally dynamic and dimeric structure
-
Bessonneau, P., Besson, V., Collinson, I., and Duong, F. (2002) The SecYEG preprotein translocation channel is a conformationally dynamic and dimeric structure, EMBO J. 21, 995-1003.
-
(2002)
EMBO J
, vol.21
, pp. 995-1003
-
-
Bessonneau, P.1
Besson, V.2
Collinson, I.3
Duong, F.4
-
23
-
-
27844444793
-
Structure of the E. coli protein-conducting channel bound to a translating ribosome
-
Mitra, K., Schaffitzel, C., Shaikh, T., Tama, F., Jenni, S., Brooks, C. L., Ban, N., and Frank, J. (2005) Structure of the E. coli protein-conducting channel bound to a translating ribosome, Nature 438, 318-324.
-
(2005)
Nature
, vol.438
, pp. 318-324
-
-
Mitra, K.1
Schaffitzel, C.2
Shaikh, T.3
Tama, F.4
Jenni, S.5
Brooks, C.L.6
Ban, N.7
Frank, J.8
-
24
-
-
0345444027
-
Oligomeric rings of the Sec61p complex induced by ligands required for protein translocation
-
Hanein, D., Matlack, K. E. S., Jungnickel, B., Plath, K., Kalies, K.-U., Miller, K. R., Rapoport, T. A., and Akey, C. W. (1996) Oligomeric rings of the Sec61p complex induced by ligands required for protein translocation, Cell 87, 721-732.
-
(1996)
Cell
, vol.87
, pp. 721-732
-
-
Hanein, D.1
Matlack, K.E.S.2
Jungnickel, B.3
Plath, K.4
Kalies, K.-U.5
Miller, K.R.6
Rapoport, T.A.7
Akey, C.W.8
-
25
-
-
16244373735
-
Architecture of the ribosome-channel complex derived from native membranes
-
Ménétret, J. F.. Hegde, R. S., Heinrich, S. U., Chandramouli, P., Ludtke, S. J., Rapoport, T. A., and Akey, C. W. (2005) Architecture of the ribosome-channel complex derived from native membranes, J. Mol. Biol. 348, 445-457.
-
(2005)
J. Mol. Biol
, vol.348
, pp. 445-457
-
-
Ménétret, J.F.1
Hegde, R.S.2
Heinrich, S.U.3
Chandramouli, P.4
Ludtke, S.J.5
Rapoport, T.A.6
Akey, C.W.7
-
26
-
-
0033551435
-
Cysteine-directed cross-linking demonstrates that helix 3 of SecE is close to helix 2 of SecY and helix 3 of a neighboring SecE
-
Kaufmann, A., Manting, E. H., Veenendaal, A. K. J., Driessen, A. J. M., and van der Does, C. (1999) Cysteine-directed cross-linking demonstrates that helix 3 of SecE is close to helix 2 of SecY and helix 3 of a neighboring SecE, Biochemistry 38, 9115-9125.
-
(1999)
Biochemistry
, vol.38
, pp. 9115-9125
-
-
Kaufmann, A.1
Manting, E.H.2
Veenendaal, A.K.J.3
Driessen, A.J.M.4
van der Does, C.5
-
27
-
-
0035980042
-
Mapping the sites of interaction between SecY and SecE by cysteine scanning mutagenesis
-
Veenendaal, A. K., van der Does, C., and Driessen, A. J. (2001) Mapping the sites of interaction between SecY and SecE by cysteine scanning mutagenesis, J. Biol. Chem. 276, 32559-32566.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 32559-32566
-
-
Veenendaal, A.K.1
van der Does, C.2
Driessen, A.J.3
-
28
-
-
24944458963
-
Atomic model of the E. coli membrane-bound protein translocation complex SecYEG
-
Bostina, M., Mohsin, B., Kühlbrandt, W., and Collinson, I. (2005) Atomic model of the E. coli membrane-bound protein translocation complex SecYEG, J. Mol. Biol. 352, 1035-1043.
-
(2005)
J. Mol. Biol
, vol.352
, pp. 1035-1043
-
-
Bostina, M.1
Mohsin, B.2
Kühlbrandt, W.3
Collinson, I.4
-
29
-
-
33646931831
-
A model for co-translational translocation: Ribosome-regulated nascent polypeptide translocation at the protein-conducting channel
-
Mitra, K., and Frank, J. (2006) A model for co-translational translocation: Ribosome-regulated nascent polypeptide translocation at the protein-conducting channel, FEBS Lett. 580, 3353-3360.
-
(2006)
FEBS Lett
, vol.580
, pp. 3353-3360
-
-
Mitra, K.1
Frank, J.2
-
30
-
-
33750580851
-
Co- and post-translational translocation through the protein-conducting channel: Analogous mechanisms at work?
-
Mitra, K., Frank, J., and Driessen, A. (2006) Co- and post-translational translocation through the protein-conducting channel: Analogous mechanisms at work? Nat. Struct. Mol. Biol. 13, 957-964.
-
(2006)
Nat. Struct. Mol. Biol
, vol.13
, pp. 957-964
-
-
Mitra, K.1
Frank, J.2
Driessen, A.3
-
31
-
-
0029878720
-
VMD - Visual molecular dynamics
-
Humphrey, W., Dalke, A., and Schulten, K. (1996) VMD - Visual molecular dynamics, J. Mol. Graphics Modell. 14, 33-38.
-
(1996)
J. Mol. Graphics Modell
, vol.14
, pp. 33-38
-
-
Humphrey, W.1
Dalke, A.2
Schulten, K.3
-
32
-
-
27344436659
-
Scalable molecular dynamics with NAMD
-
Phillips, J. C., Braun, R., Wang, W., Gumbart, J., Tajkhorshid, E., Villa, E., Chipot, C., Skeel, R. D., Kale, L., and Schulten, K. (2005) Scalable molecular dynamics with NAMD, J. Comp. Chem. 26, 1781-1802.
-
(2005)
J. Comp. Chem
, vol.26
, pp. 1781-1802
-
-
Phillips, J.C.1
Braun, R.2
Wang, W.3
Gumbart, J.4
Tajkhorshid, E.5
Villa, E.6
Chipot, C.7
Skeel, R.D.8
Kale, L.9
Schulten, K.10
-
33
-
-
0041784950
-
-
MacKerell, A. D., Jr., Bashford, D., Bellott, M., Dunbrack, R. L., Jr., Evanseck, J., Field, M. J., Fischer, S., Gao, J., Guo, H., Ha, S., Joseph, D., Kuchnir, L., Kuczera, K., Lau, F. T. K., Mattos, C., Michnick, S., Ngo, T., Nguyen, D. T., Prodhom, B., Reiher, I. W. E., Roux, B., Schlenkrich, M., Smith, J., Stote, R., Straub, J., Watanabe, M., Wiorkiewicz-Kuczera, J., Yin, D., and Karplus, M. (1998) All-atom empirical potential for molecular modeling and dynamics studies of proteins, J. Phys. Chem. B 102, 3586-3616.
-
MacKerell, A. D., Jr., Bashford, D., Bellott, M., Dunbrack, R. L., Jr., Evanseck, J., Field, M. J., Fischer, S., Gao, J., Guo, H., Ha, S., Joseph, D., Kuchnir, L., Kuczera, K., Lau, F. T. K., Mattos, C., Michnick, S., Ngo, T., Nguyen, D. T., Prodhom, B., Reiher, I. W. E., Roux, B., Schlenkrich, M., Smith, J., Stote, R., Straub, J., Watanabe, M., Wiorkiewicz-Kuczera, J., Yin, D., and Karplus, M. (1998) All-atom empirical potential for molecular modeling and dynamics studies of proteins, J. Phys. Chem. B 102, 3586-3616.
-
-
-
-
34
-
-
1642485164
-
Coarse grained model for semiquantitative lipid simulations
-
Marrink, S. J., de Vries, A. H., and Mark, A. E. (2004) Coarse grained model for semiquantitative lipid simulations, J. Phys. Chem. B 108, 750-760.
-
(2004)
J. Phys. Chem. B
, vol.108
, pp. 750-760
-
-
Marrink, S.J.1
de Vries, A.H.2
Mark, A.E.3
-
35
-
-
33644893631
-
Coarse grained protein-lipid model with application to lipoprotein particles
-
Shih, A. Y., Arkhipov, A., Freddolino, P. L., and Schulten, K. (2006) Coarse grained protein-lipid model with application to lipoprotein particles, J. Phys. Chem. B 110, 3674-3684.
-
(2006)
J. Phys. Chem. B
, vol.110
, pp. 3674-3684
-
-
Shih, A.Y.1
Arkhipov, A.2
Freddolino, P.L.3
Schulten, K.4
-
36
-
-
33847193915
-
Assembly of lipoprotein particles revealed by coarse-grained molecular dynamics simulations
-
Shih, A. Y., Freddolino, P. L., Arkhipov, A., and Schulten, K. (2007) Assembly of lipoprotein particles revealed by coarse-grained molecular dynamics simulations, J. Struct. Biol. 157, 579-592.
-
(2007)
J. Struct. Biol
, vol.157
, pp. 579-592
-
-
Shih, A.Y.1
Freddolino, P.L.2
Arkhipov, A.3
Schulten, K.4
-
37
-
-
0030987036
-
Molecular dynamics study of unbinding of the avidin-biotin complex
-
Izrailev, S., Stepaniants, S., Baisera, M., Oono, Y., and Schulten, K. (1997) Molecular dynamics study of unbinding of the avidin-biotin complex, Biophys. J. 72, 1568-1581.
-
(1997)
Biophys. J
, vol.72
, pp. 1568-1581
-
-
Izrailev, S.1
Stepaniants, S.2
Baisera, M.3
Oono, Y.4
Schulten, K.5
-
38
-
-
0035312645
-
Steered molecular dynamics and mechanical functions of proteins
-
Isralewitz, B., Gao, M., and Schulten, K. (2001) Steered molecular dynamics and mechanical functions of proteins, Curr. Opin. Struct. Biol. 11, 224-230.
-
(2001)
Curr. Opin. Struct. Biol
, vol.11
, pp. 224-230
-
-
Isralewitz, B.1
Gao, M.2
Schulten, K.3
-
39
-
-
33750337536
-
How the headpiece hinge angle is opened: New insights into the dynamics of integrin activation
-
Puklin-Faucher, E., Gao, M., Schulten, K., and Vogel, V. (2006) How the headpiece hinge angle is opened: New insights into the dynamics of integrin activation, J. Cell Biol. 175, 349-360.
-
(2006)
J. Cell Biol
, vol.175
, pp. 349-360
-
-
Puklin-Faucher, E.1
Gao, M.2
Schulten, K.3
Vogel, V.4
-
40
-
-
33749442647
-
MultiSeq: Unifying sequence and structure data for evolutionary analysis
-
Roberts, E., Eargle, J., Wright, D., and Luthey-Schulten, Z. (2006) MultiSeq: Unifying sequence and structure data for evolutionary analysis, BMC Bioinformatics 7, 382.
-
(2006)
BMC Bioinformatics
, vol.7
, pp. 382
-
-
Roberts, E.1
Eargle, J.2
Wright, D.3
Luthey-Schulten, Z.4
-
41
-
-
0002174423
-
Lecture notes in computational science and engineering
-
Deuflhard, P, Hermans, J, Leimkuhler, B, Mark, A. E, Reich, S, and Skeel, R. D, Eds, Springer-Verlag, Berlin, Germany
-
Izrailev, S., Stepaniants, S., Isralewitz, B., Kosztin, D., Lu, H., Molnar, F., Wriggers, W., and Schulten, K. (1998) Lecture notes in computational science and engineering, in Computational Molecular Dynamics: Challenges, Methods, Ideas (Deuflhard, P., Hermans, J., Leimkuhler, B., Mark, A. E., Reich, S., and Skeel, R. D., Eds.) Vol. 4, pp. 39-65, Springer-Verlag, Berlin, Germany.
-
(1998)
Computational Molecular Dynamics: Challenges, Methods, Ideas
, vol.4
, pp. 39-65
-
-
Izrailev, S.1
Stepaniants, S.2
Isralewitz, B.3
Kosztin, D.4
Lu, H.5
Molnar, F.6
Wriggers, W.7
Schulten, K.8
-
42
-
-
0035003803
-
Steered molecular dynamics investigations of protein function
-
Isralewitz, B., Baudry, J., Gullingsrud, J., Kosztin, D., and Schulten, K. (2001) Steered molecular dynamics investigations of protein function, J. Mol. Graphics Modell. 19, 13-25.
-
(2001)
J. Mol. Graphics Modell
, vol.19
, pp. 13-25
-
-
Isralewitz, B.1
Baudry, J.2
Gullingsrud, J.3
Kosztin, D.4
Schulten, K.5
-
43
-
-
33749856031
-
Molecular mechanisms of cellular mechanics
-
Gao, M., Sotomayor, M., Villa, E., Lee, E., and Schulten, K. (2006) Molecular mechanisms of cellular mechanics, Phys. Chem. Chem. Phys. 8, 3692-3706.
-
(2006)
Phys. Chem. Chem. Phys
, vol.8
, pp. 3692-3706
-
-
Gao, M.1
Sotomayor, M.2
Villa, E.3
Lee, E.4
Schulten, K.5
-
44
-
-
0033523904
-
Mechanical unfolding intermediates in titin modules
-
Marszalek, P. E., Lu, H., Li, H., Carrion-Vazquez, M., Oberhauser, A. F., Schulten, K., and Fernandez, J. M. (1999) Mechanical unfolding intermediates in titin modules, Nature 402, 100-103.
-
(1999)
Nature
, vol.402
, pp. 100-103
-
-
Marszalek, P.E.1
Lu, H.2
Li, H.3
Carrion-Vazquez, M.4
Oberhauser, A.F.5
Schulten, K.6
Fernandez, J.M.7
-
45
-
-
0344736695
-
Structure and functional significance of mechanically unfolded fibronectin type III1 intermediates
-
Gao, M., Craig, D., Lequin, O., Campbell, I. D., Vogel, V., and Schulten, K. (2003) Structure and functional significance of mechanically unfolded fibronectin type III1 intermediates, Proc. Natl. Acad. Sci. U.S.A. 100, 14784-14789.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A
, vol.100
, pp. 14784-14789
-
-
Gao, M.1
Craig, D.2
Lequin, O.3
Campbell, I.D.4
Vogel, V.5
Schulten, K.6
-
46
-
-
17044401714
-
In search of the hair-cell gating spring: Elastic properties of ankyrin and Cadherin repeats
-
Sotomayor, M., Corey, D. P., and Schulten, K. (2005) In search of the hair-cell gating spring: Elastic properties of ankyrin and Cadherin repeats, Structure 13, 669-682.
-
(2005)
Structure
, vol.13
, pp. 669-682
-
-
Sotomayor, M.1
Corey, D.P.2
Schulten, K.3
-
47
-
-
33644849450
-
Nanospring behaviour of ankyrin repeats
-
Lee, G., Abdi, K., Jiang, Y., Michaely, P., Bennett, V., and Marszalek, P. E. (2006) Nanospring behaviour of ankyrin repeats, Nature 440, 246-249.
-
(2006)
Nature
, vol.440
, pp. 246-249
-
-
Lee, G.1
Abdi, K.2
Jiang, Y.3
Michaely, P.4
Bennett, V.5
Marszalek, P.E.6
-
48
-
-
33645770767
-
Stepwise unfolding of ankyrin repeats in a single protein revealed by atomic force microscopy
-
Li, L., Wetzel, S., Pluckthun, A., and Fernandez, J. M. (2006) Stepwise unfolding of ankyrin repeats in a single protein revealed by atomic force microscopy, Biophys. J. 90, L30-L32.
-
(2006)
Biophys. J
, vol.90
-
-
Li, L.1
Wetzel, S.2
Pluckthun, A.3
Fernandez, J.M.4
-
49
-
-
34249930159
-
Single-molecule experiments in vitro and in silico
-
Sotomayor, M., and Schulten, K. (2007) Single-molecule experiments in vitro and in silico, Science 316, 1144-1148.
-
(2007)
Science
, vol.316
, pp. 1144-1148
-
-
Sotomayor, M.1
Schulten, K.2
-
50
-
-
33646191829
-
Size, motion, and function of the SecY translocon revealed by molecular dynamics simulations with virtual probes
-
Tian, P., and Andricioaei, I. (2006) Size, motion, and function of the SecY translocon revealed by molecular dynamics simulations with virtual probes, Biophys. J. 90, 2718-2730.
-
(2006)
Biophys. J
, vol.90
, pp. 2718-2730
-
-
Tian, P.1
Andricioaei, I.2
-
51
-
-
33751074442
-
Simulations of a protein translocation pore: SecY
-
Haider, S., Hall, B. A., and Sansom, M. S. P. (2006) Simulations of a protein translocation pore: SecY, Biochemistry 45, 13018-13024.
-
(2006)
Biochemistry
, vol.45
, pp. 13018-13024
-
-
Haider, S.1
Hall, B.A.2
Sansom, M.S.P.3
-
52
-
-
0030883755
-
Protein domain movements: Detection of rigid domains and visualization of hinges in comparisons of atomic coordinates
-
Wriggers, W., and Schulten, K. (1997) Protein domain movements: Detection of rigid domains and visualization of hinges in comparisons of atomic coordinates, Proteins: Struct., Funct., Genet. 29, 1-14.
-
(1997)
Proteins: Struct., Funct., Genet
, vol.29
, pp. 1-14
-
-
Wriggers, W.1
Schulten, K.2
-
53
-
-
0030888546
-
Model-free methods of analyzing domain motions in proteins from simulation: A comparison of normal mode analysis and molecular dynamics simulation of lysozyme
-
Hayward, S., Kitao, A., and Berendsen, H. J. C. (1997) Model-free methods of analyzing domain motions in proteins from simulation: A comparison of normal mode analysis and molecular dynamics simulation of lysozyme, Proteins: Struct, Funct., Genet. 27, 425-437.
-
(1997)
Proteins: Struct, Funct., Genet
, vol.27
, pp. 425-437
-
-
Hayward, S.1
Kitao, A.2
Berendsen, H.J.C.3
-
54
-
-
0032568540
-
Free energy of burying hydrophobic residues in the interface between protein subunits
-
Vallone, B., Miele, A. E., Vecchini, P., Chiancone, E., and Brunori, M. (1998) Free energy of burying hydrophobic residues in the interface between protein subunits, Proc. Natl. Acad. Sci. U.S.A. 95, 6103-6107.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A
, vol.95
, pp. 6103-6107
-
-
Vallone, B.1
Miele, A.E.2
Vecchini, P.3
Chiancone, E.4
Brunori, M.5
-
55
-
-
33644644163
-
Insertion and assembly of membrane proteins via simulation
-
Bond, P. J., and Sansom, M. S. P. (2006) Insertion and assembly of membrane proteins via simulation, J. Am. Chem. Soc. 128, 2697-2704.
-
(2006)
J. Am. Chem. Soc
, vol.128
, pp. 2697-2704
-
-
Bond, P.J.1
Sansom, M.S.P.2
-
56
-
-
33847242278
-
Coarse-grained molecular dynamics simulations of membrane proteins and peptides
-
Bond, P. J., Holyoake, J., Ivetac, A., Khalid, S., and Sansom, M. (2007) Coarse-grained molecular dynamics simulations of membrane proteins and peptides, J. Struct. Biol. 157, 593-605.
-
(2007)
J. Struct. Biol
, vol.157
, pp. 593-605
-
-
Bond, P.J.1
Holyoake, J.2
Ivetac, A.3
Khalid, S.4
Sansom, M.5
-
57
-
-
33847258823
-
Bilayer deformation by the Kv channel voltage sensor domain revealed by self-assembly simulations
-
Bond, P. J., and Sansom, M. (2007) Bilayer deformation by the Kv channel voltage sensor domain revealed by self-assembly simulations, Proc. Natl. Acad. Sci. U.S.A. 104, 2631-2636.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A
, vol.104
, pp. 2631-2636
-
-
Bond, P.J.1
Sansom, M.2
-
58
-
-
0025732834
-
One of three transmembrane stretches is sufficient for the functioning of the SecE protein, a membrane component of the E. coli secretion machinery
-
Schatz, P. J., Bieker, K. L., Ottemann, K. M., Silhavy, T. J., and Beckwith, J. (1991) One of three transmembrane stretches is sufficient for the functioning of the SecE protein, a membrane component of the E. coli secretion machinery, EMBO J. 10, 1749-1757.
-
(1991)
EMBO J
, vol.10
, pp. 1749-1757
-
-
Schatz, P.J.1
Bieker, K.L.2
Ottemann, K.M.3
Silhavy, T.J.4
Beckwith, J.5
-
59
-
-
0026688434
-
The carboxyl-terminal region of SecE interacts with SecY and is functional in the reconstitution of protein translocation activity in Escherichia coli
-
Nishiyama, K., Mizushima, S., and Tokuda, H. (1992) The carboxyl-terminal region of SecE interacts with SecY and is functional in the reconstitution of protein translocation activity in Escherichia coli, J. Biol. Chem. 267, 7170-7176.
-
(1992)
J. Biol. Chem
, vol.267
, pp. 7170-7176
-
-
Nishiyama, K.1
Mizushima, S.2
Tokuda, H.3
-
60
-
-
0028334912
-
Residues essential for the function of SecE, a membrane component of the Escherichia coli secretion apparatus, are located in a conserved cytoplasmic region
-
Murphy, C. K., and Beckwith, J. (1994) Residues essential for the function of SecE, a membrane component of the Escherichia coli secretion apparatus, are located in a conserved cytoplasmic region, Proc. Natl. Acad. Sci. U.S.A. 91, 2557-2561.
-
(1994)
Proc. Natl. Acad. Sci. U.S.A
, vol.91
, pp. 2557-2561
-
-
Murphy, C.K.1
Beckwith, J.2
-
61
-
-
0037361759
-
Interfering mutations provide in vivo evidence that Escherichia coli SecE functions in multimeric states
-
Matsuo, E., Mori, H., and Ito, K. (2003) Interfering mutations provide in vivo evidence that Escherichia coli SecE functions in multimeric states, Mol. Gen. Genomics 268, 808-815.
-
(2003)
Mol. Gen. Genomics
, vol.268
, pp. 808-815
-
-
Matsuo, E.1
Mori, H.2
Ito, K.3
-
62
-
-
0029989855
-
FtsH (Hf1B) is an ATP-dependent protease selectively acting on SecY and some other membrane proteins
-
Akiyama, Y., Kihara, A., Tokuda, H., and Ito, K. (1996) FtsH (Hf1B) is an ATP-dependent protease selectively acting on SecY and some other membrane proteins, J. Biol. Chem. 271, 31196-31201.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 31196-31201
-
-
Akiyama, Y.1
Kihara, A.2
Tokuda, H.3
Ito, K.4
-
63
-
-
0034293329
-
Role of the non-essential region encompassing the N-terminal two transmembrane stretches of Escherichia coli SecE
-
Nishiyama, K., Suzuki, H., and Tokuda, H. (2000) Role of the non-essential region encompassing the N-terminal two transmembrane stretches of Escherichia coli SecE, Biosci., Biotechnol., Biochem. 64, 2121-2127.
-
(2000)
Biosci., Biotechnol., Biochem
, vol.64
, pp. 2121-2127
-
-
Nishiyama, K.1
Suzuki, H.2
Tokuda, H.3
-
64
-
-
0029810616
-
In vivo analyses of interactions between SecE and SecY, core components of the Escherichia coli protein translocation machinery
-
Pohlschröder, M., Murphy, C., and Beckwith, J. (1996) In vivo analyses of interactions between SecE and SecY, core components of the Escherichia coli protein translocation machinery, J. Biol. Chem. 271, 19908-19914.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 19908-19914
-
-
Pohlschröder, M.1
Murphy, C.2
Beckwith, J.3
-
65
-
-
0032719682
-
Preprotein translocation by a hybrid translocase composed of Escherichia coli and Bacillus subtilis subunits
-
Swaving, J., van Wely, K. H. M., and Driessen, A. J. M. (1999) Preprotein translocation by a hybrid translocase composed of Escherichia coli and Bacillus subtilis subunits, J. Bacteriol. 181, 7021-7027.
-
(1999)
J. Bacteriol
, vol.181
, pp. 7021-7027
-
-
Swaving, J.1
van Wely, K.H.M.2
Driessen, A.J.M.3
-
66
-
-
27144525002
-
Investigating the SecY plug movement at the SecYEG translocation channel
-
Tarn, P. C. K., Maillard, A. P., Chan, K. K. Y., and Duong, F. (2005) Investigating the SecY plug movement at the SecYEG translocation channel, EMBO J. 24, 3380-3388.
-
(2005)
EMBO J
, vol.24
, pp. 3380-3388
-
-
Tarn, P.C.K.1
Maillard, A.P.2
Chan, K.K.Y.3
Duong, F.4
-
67
-
-
0032544614
-
Signal sequence recognition in posttranslational protein transport across the yeast ER membrane
-
Plath, K., Mothes, W., Wilkinson, B. M., Stirling, C. J., and Rapoport, T. A. (1998) Signal sequence recognition in posttranslational protein transport across the yeast ER membrane, Cell 94, 795-807.
-
(1998)
Cell
, vol.94
, pp. 795-807
-
-
Plath, K.1
Mothes, W.2
Wilkinson, B.M.3
Stirling, C.J.4
Rapoport, T.A.5
-
68
-
-
0029002962
-
The protein-conducting channel in the membrane of the endoplasmic reticulum is open laterally toward the lipid bilayer
-
Martoglio, B., Hofmann, M. W., Brunner, J., and Dobberstein, B. (1995) The protein-conducting channel in the membrane of the endoplasmic reticulum is open laterally toward the lipid bilayer, Cell 81, 207-214.
-
(1995)
Cell
, vol.81
, pp. 207-214
-
-
Martoglio, B.1
Hofmann, M.W.2
Brunner, J.3
Dobberstein, B.4
-
69
-
-
0034697967
-
The Sec61p complex mediates the integration of a membrane protein by allowing lipid partitioning of the transmembrane domain
-
Heinrich, S. U., Mothes, W., Brunner, J., and Rapoport, T. A. (2000) The Sec61p complex mediates the integration of a membrane protein by allowing lipid partitioning of the transmembrane domain, Cell 102, 233-244.
-
(2000)
Cell
, vol.102
, pp. 233-244
-
-
Heinrich, S.U.1
Mothes, W.2
Brunner, J.3
Rapoport, T.A.4
-
70
-
-
13544259578
-
Probing the environment of signal-anchor sequences during topogenesis in the endoplasmic reticulum
-
Higy, M., Gander, S., and Spiess, M. (2005) Probing the environment of signal-anchor sequences during topogenesis in the endoplasmic reticulum, Biochemistry 44, 2039-2047.
-
(2005)
Biochemistry
, vol.44
, pp. 2039-2047
-
-
Higy, M.1
Gander, S.2
Spiess, M.3
-
71
-
-
34247580102
-
Membrane protein integration: The biology-physics nexus
-
White, S. H. (2007) Membrane protein integration: The biology-physics nexus, J. Gen. Physiol. 129, 363-369.
-
(2007)
J. Gen. Physiol
, vol.129
, pp. 363-369
-
-
White, S.H.1
-
72
-
-
4143107016
-
Structural insight into the protein translocation channel
-
Clemons, W. M., Jr., Ménétret, J. F., Akey, C. W., and Rapoport, T. A. (2004) Structural insight into the protein translocation channel, Curr. Opin. Struct. Biol. 14, 390-396.
-
(2004)
Curr. Opin. Struct. Biol
, vol.14
, pp. 390-396
-
-
Clemons Jr., W.M.1
Ménétret, J.F.2
Akey, C.W.3
Rapoport, T.A.4
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