Interaction of calmodulin with Sec61α limits Ca2+ leakage from the endoplasmic reticulum

EMBO Journal

Volumn 30, Issue 1, 2011, Pages 17-31

  Erdmann, Frank ^a,d   Schäuble, Nico ^b,d   Lang, Sven ^b   Jung, Martin ^b   Honigmann, Alf ^a   Ahmad, Mazen ^c   Dudek, Johanna ^b   Benedix, Julia ^b   Harsman, Anke ^a   Kopp, Annika ^a   Helms, Volkhard ^c   Cavalié, Adolfo ^b   Wagner, Richard ^a   Zimmermann, Richard ^b  

^a UNIVERSITY OF OSNABRÜCK   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c SAARLAND UNIVERSITY   (Germany)

^d UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

calmodulin; endoplasmic reticulum; ER calcium leakage; IQ motif; Sec61 complex

Indexed keywords

APOCALMODULIN; CALCIUM BINDING PROTEIN; CALCIUM ION; CALMODULIN; CALMODULIN INHIBITOR; CARRIER PROTEIN; OPHIBOLIN A; PROTEIN SEC61ALPHA; RIBOSOME PROTEIN; TRIFLUOPERAZINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CELL MEMBRANE; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOSOL; DRUG BINDING; DRUG INHIBITION; ENDOPLASMIC RETICULUM; FEMALE; HUMAN; HUMAN CELL; MICROSOME; MOLECULAR MODEL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RIBOSOME; SEQUENCE ANALYSIS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CALCIUM; CALMODULIN; ENDOPLASMIC RETICULUM; HELA CELLS; HUMANS; MEMBRANE PROTEINS; MICROSOMES; MOLECULAR SEQUENCE DATA; PROTEIN SUBUNITS; PROTEIN TRANSPORT; WOLVES;

EUKARYOTA; MAMMALIA;

EID: 78650905148     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2010.284     Document Type: Article

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