Combined use of extract libraries and hplc-based activity profiling for lead discovery: Potential, challenges, and practical considerations

Planta Medica

Volumn 80, Issue 14, 2014, Pages 1171-1181

  Potterat, Olivier ^a   Hamburger, Matthias ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

Author keywords

database; extract library; HPLC based activity profiling; microfractionation

Indexed keywords

MOLECULAR LIBRARY; PLANT EXTRACT;

BIOASSAY; CHEMISTRY; DRUG DEVELOPMENT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MASS SPECTROMETRY; MOLECULAR LIBRARY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLANT; PROCEDURES;

BIOLOGICAL ASSAY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG DISCOVERY; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; PLANT EXTRACTS; PLANTS; SMALL MOLECULE LIBRARIES;

EID: 84930193453     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0034-1382900     Document Type: Review

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