Fructose induces mitochondrial dysfunction and triggers apoptosis in skeletal muscle cells by provoking oxidative stress

Apoptosis

Volumn 20, Issue 7, 2015, Pages 930-947

  Jaiswal, Natasha ^a   Maurya, Chandan K ^a   Arha, Deepti ^a   Avisetti, Deepa R ^b   Prathapan, Ayyappan ^c   Raj, Palayyan S ^c   Raghu, Kozhiparambil G ^c   Kalivendi, Shasi V ^b   Tamrakar, Akhilesh Kumar ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^c REGIONAL RESEARCH LABORATORY CSIR   (India)

Author keywords

Apoptosis; Fructose; Mitochondrial dysfunction; Oxidative stress; Skeletal muscle

Indexed keywords

CASPASE; CITRATE SYNTHASE; FRUCTOSE; MITOCHONDRIAL DNA; MITOCHONDRIAL ENZYME; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXIDOREDUCTASE; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; INDUCIBLE NITRIC OXIDE SYNTHASE; NFE2L2 PROTEIN, RAT; NOS2 PROTEIN, RAT;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENERGY METABOLISM; ENZYME ACTIVITY; GENE TRANSLOCATION; LONG TERM EXPOSURE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL MYOPATHY; MITOCHONDRION; MUSCLE CELL; MYOTUBE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SKELETAL MUSCLE; ANIMAL; CELL LINE; DRUG EFFECTS; METABOLISM; MUSCLE MITOCHONDRION;

ANIMALS; APOPTOSIS; CELL LINE; CITRATE (SI)-SYNTHASE; DNA, MITOCHONDRIAL; ENERGY METABOLISM; FRUCTOSE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA, MUSCLE; MUSCLE, SKELETAL; NF-E2-RELATED FACTOR 2; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; RATS; REACTIVE OXYGEN SPECIES;

EID: 84930182595     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-015-1128-y     Document Type: Article

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