PPARγ-dependent and -independent inhibition of the HMGB1/TLR9 pathway by eicosapentaenoic acid attenuates ischemic brain damage in ovariectomized rats

Journal of Stroke and Cerebrovascular Diseases

Volumn 24, Issue 6, 2015, Pages 1187-1195

  Sumiyoshi, Manabu ^a   Satomi, Junichiro ^a   Kitazato, Keiko T ^a   Yagi, Kenji ^a   Shimada, Kenji ^a   Kurashiki, Yoshitaka ^a   Korai, Masaaki ^a   Miyamoto, Takeshi ^a   Suzue, Ryoko ^a   Kuwayama, Kazuyuki ^a   Nagahiro, Shinji ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

Author keywords

brain ischemia; Eicosapentaenoic acid; HMGB1; ovariectomy; PPAR ; RAGE; toll like receptors

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; ADVANCED GLYCATION END PRODUCT RECEPTOR; HIGH MOBILITY GROUP B1 PROTEIN; ICOSAPENTAENOIC ACID; MESSENGER RNA; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA; 2-CHLORO-5-NITROBENZANILIDE; ANILIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN DAMAGE; BRAIN ISCHEMIA; CONTROLLED STUDY; DOWN REGULATION; FEMALE; MALE; MALE ANIMAL; NEUROPROTECTION; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN; DRUG EFFECTS; METABOLISM; PATHOLOGY; UPREGULATION;

ANILIDES; ANIMALS; BRAIN; BRAIN ISCHEMIA; EICOSAPENTAENOIC ACID; FEMALE; HMGB1 PROTEIN; OVARIECTOMY; PPAR GAMMA; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 9; UP-REGULATION;

EID: 84930179213     PISSN: 10523057     EISSN: 15328511     Source Type: Journal    
DOI: 10.1016/j.jstrokecerebrovasdis.2015.01.009     Document Type: Article

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