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Volumn 11, Issue 6, 2015, Pages 354-370

Renal effects of targeted anticancer therapies

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4 ANTIBODY; DABRAFENIB; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; IMATINIB; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; SORAFENIB; TRAMETINIB; VASCULOTROPIN RECEPTOR; VEMURAFENIB; ANGIOGENESIS INHIBITOR; BEVACIZUMAB; CTLA4 PROTEIN, HUMAN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; EVEROLIMUS; MTOR PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE; VASCULOTROPIN A;

EID: 84930043826     PISSN: 17595061     EISSN: 1759507X     Source Type: Journal    
DOI: 10.1038/nrneph.2015.15     Document Type: Review
Times cited : (84)

References (167)
  • 1
    • 34548787904 scopus 로고    scopus 로고
    • Prevalence of renal insufficiency in cancer patients and implications for anticancer drug management: The Renal Insufficiency and Anticancer Medications (IRMA) study
    • Launay-Vacher, V. et al. Prevalence of renal insufficiency in cancer patients and implications for anticancer drug management: the Renal Insufficiency and Anticancer Medications (IRMA) study. Cancer 110, 1376-1384 (2007).
    • (2007) Cancer , vol.110 , pp. 1376-1384
    • Launay-Vacher, V.1
  • 2
    • 78649917189 scopus 로고    scopus 로고
    • Epidemiology of chronic kidney disease in cancer patients: Lessons from the IRMA study group
    • Launay-Vacher, V. Epidemiology of chronic kidney disease in cancer patients: lessons from the IRMA study group. Semin. Nephrol. 30, 548-556 (2010).
    • (2010) Semin. Nephrol. , vol.30 , pp. 548-556
    • Launay-Vacher, V.1
  • 4
    • 84880121650 scopus 로고    scopus 로고
    • Chronic kidney disease in the elderly
    • Maw, T. T. & Fried, L. Chronic kidney disease in the elderly. Clin. Geriat. Med. 29, 611-624 (2013).
    • (2013) Clin. Geriat. Med. , vol.29 , pp. 611-624
    • Maw, T.T.1    Fried, L.2
  • 5
    • 2642573558 scopus 로고    scopus 로고
    • Participation in cancer clinical trials: Race, sex, and age-based disparities
    • Murthy, V. H., Krumholz, H. M. & Gross, C. P. Participation in cancer clinical trials: race, sex, and age-based disparities. JAMA 291, 2720-2726 (2004).
    • (2004) JAMA , vol.291 , pp. 2720-2726
    • Murthy, V.H.1    Krumholz, H.M.2    Gross, C.P.3
  • 6
    • 84898744858 scopus 로고    scopus 로고
    • Comparison of survival outcomes among cancer patients treated in and out of clinical trial
    • Unger, J. M. et al. Comparison of survival outcomes among cancer patients treated in and out of clinical trial. J. Natl. Cancer Inst. 106, dju002 (2014).
    • (2014) J. Natl. Cancer Inst. , vol.106 , pp. dju002
    • Unger, J.M.1
  • 8
    • 84990978773 scopus 로고    scopus 로고
    • Impact of adverse events, treatment modifications, and dose intensity on survival among patients with advanced renal cell carcinoma treated with first-line sunitinib: A medical chart review across ten centers in five European countries
    • Porta, C. et al. Impact of adverse events, treatment modifications, and dose intensity on survival among patients with advanced renal cell carcinoma treated with first-line sunitinib: a medical chart review across ten centers in five European countries. Cancer Med. 3, 1517-1526 (2014).
    • (2014) Cancer Med. , vol.3 , pp. 1517-1526
    • Porta, C.1
  • 9
    • 2442621619 scopus 로고    scopus 로고
    • Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
    • Ferrara, N., Hillan, K. J., Gerber, H. P. & Novotny, W. Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat. Rev. Drug Discov. 3, 391-400 (2004).
    • (2004) Nat. Rev. Drug Discov. , vol.3 , pp. 391-400
    • Ferrara, N.1    Hillan, K.J.2    Gerber, H.P.3    Novotny, W.4
  • 10
    • 65349186800 scopus 로고    scopus 로고
    • Aflibercept (AVE0005): An alternative strategy for inhibiting tumour angiogenesis by vascular endothelial growth factors
    • Chu, Q. S. Aflibercept (AVE0005): an alternative strategy for inhibiting tumour angiogenesis by vascular endothelial growth factors. Expert Opin. Biol. Ther. 9, 263-271 (2009).
    • (2009) Expert Opin. Biol. Ther. , vol.9 , pp. 263-271
    • Chu, Q.S.1
  • 11
    • 33947504730 scopus 로고    scopus 로고
    • Sunitinib: From rational design to clinical efficacy
    • Chow, L. Q. & Eckhardt, S. G. Sunitinib: from rational design to clinical efficacy. J. Clin. Oncol. 25, 884-896 (2007).
    • (2007) J. Clin. Oncol. , vol.25 , pp. 884-896
    • Chow, L.Q.1    Eckhardt, S.G.2
  • 12
    • 33847405376 scopus 로고    scopus 로고
    • Pazopanib: A novel multitargeted tyrosine kinase inhibitor
    • Sonpavde, G. & Hutson, T. E. Pazopanib: a novel multitargeted tyrosine kinase inhibitor. Curr. Oncol. Rep. 9, 115-119 (2007).
    • (2007) Curr. Oncol. Rep. , vol.9 , pp. 115-119
    • Sonpavde, G.1    Hutson, T.E.2
  • 13
    • 84874527525 scopus 로고    scopus 로고
    • Third generation tyrosine kinase inhibitors and their development in advanced renal cell carcinoma
    • Bukowski, R. M. Third generation tyrosine kinase inhibitors and their development in advanced renal cell carcinoma. Front. Oncol. 2, 13 (2012).
    • (2012) Front. Oncol. , vol.2 , pp. 13
    • Bukowski, R.M.1
  • 14
    • 34447635695 scopus 로고    scopus 로고
    • Angiogenesis inhibitor therapies: Focus on kidney toxicity and hypertension
    • Izzedine, H., Rixe, O., Billemont, B., Baumelou, A. & Deray, G. Angiogenesis inhibitor therapies: focus on kidney toxicity and hypertension. Am. J. Kidney Dis. 50, 203-218 (2007).
    • (2007) Am. J. Kidney Dis. , vol.50 , pp. 203-218
    • Izzedine, H.1    Rixe, O.2    Billemont, B.3    Baumelou, A.4    Deray, G.5
  • 16
    • 0037631361 scopus 로고    scopus 로고
    • Neutralization of circulating vascular endothelial growth factor (VEGF) by anti-VEGF antibodies and soluble VEGF receptor 1 (sFlt-1) induces proteinuria
    • Sugimoto, H. et al. Neutralization of circulating vascular endothelial growth factor (VEGF) by anti-VEGF antibodies and soluble VEGF receptor 1 (sFlt-1) induces proteinuria. J. Biol. Chem. 278, 12605-12608 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 12605-12608
    • Sugimoto, H.1
  • 17
    • 79955624389 scopus 로고    scopus 로고
    • Crescentic glomerulonephritis associated with vascular endothelial growth factor (VEGF) inhibitor and bisphosphonate administration
    • Stylianou, K. et al. Crescentic glomerulonephritis associated with vascular endothelial growth factor (VEGF) inhibitor and bisphosphonate administration. Nephrol. Dial. Transplant. 26, 1742-1745 (2011).
    • (2011) Nephrol. Dial. Transplant. , vol.26 , pp. 1742-1745
    • Stylianou, K.1
  • 18
    • 33846515280 scopus 로고    scopus 로고
    • Nephrotic syndrome after bevacizumab: Case report and literature review
    • George, B. A., Zhou, X. J. & Toto, R. Nephrotic syndrome after bevacizumab: case report and literature review. Am. J. Kidney Dis. 49, e23-e29 (2007).
    • (2007) Am. J. Kidney Dis. , vol.49 , pp. e23-e29
    • George, B.A.1    Zhou, X.J.2    Toto, R.3
  • 19
    • 40849130173 scopus 로고    scopus 로고
    • VEGF inhibition and renal thrombotic microangiopathy
    • Eremina, V. et al. VEGF inhibition and renal thrombotic microangiopathy. N. Engl. J. Med. 358, 1129-1136 (2008).
    • (2008) N. Engl. J. Med. , vol.358 , pp. 1129-1136
    • Eremina, V.1
  • 20
    • 0034979275 scopus 로고    scopus 로고
    • Signaling mechanism mediating vascular protective actions of vascular endothelial growth factor
    • Zachary, I. Signaling mechanism mediating vascular protective actions of vascular endothelial growth factor. Am. J. Physiol. 280, C1375-C1386 (2001).
    • (2001) Am. J. Physiol. , vol.280 , pp. C1375-C1386
    • Zachary, I.1
  • 21
    • 43049085201 scopus 로고    scopus 로고
    • Blood pressure rise following angiogenesis inhibition by bevacizumab: A crucial role for microcirculation
    • Mourad, J. J., des Guetz, G., Debbabi, H. & Levy, B. I. Blood pressure rise following angiogenesis inhibition by bevacizumab: a crucial role for microcirculation. Ann. Oncol. 19, 927-934 (2008).
    • (2008) Ann. Oncol. , vol.19 , pp. 927-934
    • Mourad, J.J.1    Des Guetz, G.2    Debbabi, H.3    Levy, B.I.4
  • 22
    • 0026705732 scopus 로고
    • Endogenous nitric oxide protects against platelet aggregation and cyclic flow variations in stenosed and endothelium-injured arteries
    • Yao, S. K. et al. Endogenous nitric oxide protects against platelet aggregation and cyclic flow variations in stenosed and endothelium-injured arteries. Circulation 86, 1302-1309 (1992).
    • (1992) Circulation , vol.86 , pp. 1302-1309
    • Yao, S.K.1
  • 23
    • 14644440555 scopus 로고    scopus 로고
    • Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
    • Hicklin, D. J. & Ellis L. M. Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J. Clin. Oncol. 23, 1011-1027 (2005).
    • (2005) J. Clin. Oncol. , vol.23 , pp. 1011-1027
    • Hicklin, D.J.1    Ellis, L.M.2
  • 24
    • 34548383480 scopus 로고    scopus 로고
    • 2007 ESH-ESC practice guidelines for the management of arterial hypertension: ESH-ESC Task Force on the Management of Arterial Hypertension
    • Mancia, G. et al. 2007 ESH-ESC practice guidelines for the management of arterial hypertension: ESH-ESC Task Force on the Management of Arterial Hypertension. J. Hypertens. 25, 1751-1762 (2007).
    • (2007) J. Hypertens. , vol.25 , pp. 1751-1762
    • Mancia, G.1
  • 25
    • 65549122619 scopus 로고    scopus 로고
    • Management of hypertension in angiogenesis inhibitor-treated patients
    • Izzedine, H. et al. Management of hypertension in angiogenesis inhibitor-treated patients. Ann. Oncol. 20, 807-815 (2009).
    • (2009) Ann. Oncol. , vol.20 , pp. 807-815
    • Izzedine, H.1
  • 27
    • 38349030422 scopus 로고    scopus 로고
    • Uncovering Pandora's vase: The growing problem of new toxicities from novel anticancer agents: The case of sorafenib and sunitinib
    • Porta, C., Paglino, C., Imarisio, I. & Bonomi, L. Uncovering Pandora's vase: the growing problem of new toxicities from novel anticancer agents: the case of sorafenib and sunitinib. Clin. Exp. Med. 7, 127-134 (2007).
    • (2007) Clin. Exp. Med. , vol.7 , pp. 127-134
    • Porta, C.1    Paglino, C.2    Imarisio, I.3    Bonomi, L.4
  • 28
    • 84855501328 scopus 로고    scopus 로고
    • The impact of kidney function on the outcome of metastatic renal cell carcinoma patients treated with vascular endothelial growth factor-targeted therapy
    • MacFarlane, R. et al. The impact of kidney function on the outcome of metastatic renal cell carcinoma patients treated with vascular endothelial growth factor-targeted therapy. Cancer 118, 365-370 (2012).
    • (2012) Cancer , vol.118 , pp. 365-370
    • Macfarlane, R.1
  • 29
    • 77954843443 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of sunitinib malate in subjects with impaired renal function
    • Khosravan, R. et al. Pharmacokinetics and safety of sunitinib malate in subjects with impaired renal function. J. Clin. Pharmacol. 50, 472-481 (2009).
    • (2009) J. Clin. Pharmacol. , vol.50 , pp. 472-481
    • Khosravan, R.1
  • 30
    • 80051537982 scopus 로고    scopus 로고
    • Safety and efficacy of targeted agents in metastatic kidney cancer patients with renal dysfunction
    • Gupta, S. et al. Safety and efficacy of targeted agents in metastatic kidney cancer patients with renal dysfunction. Anticancer Drugs 22, 794-800 (2011).
    • (2011) Anticancer Drugs , vol.22 , pp. 794-800
    • Gupta, S.1
  • 31
    • 85027956253 scopus 로고    scopus 로고
    • Management of adverse events of targeted therapies in normal and special patients with metastatic renal cell carcinoma
    • Méndez-Vidal, M. J., Martínez Ortega, E., Montesa Pino, A., Pérez Valderrama, B. & Viciana, R. Management of adverse events of targeted therapies in normal and special patients with metastatic renal cell carcinoma. Cancer Metastasis Rev. 31 (Suppl. 1), S19-S27 (2012).
    • (2012) Cancer Metastasis Rev. , vol.31 , pp. S19-S27
    • Méndez-Vidal, M.J.1    Martínez Ortega, E.2    Montesa Pino, A.3    Pérez Valderrama, B.4    Viciana, R.5
  • 32
    • 33847677121 scopus 로고    scopus 로고
    • Pharmacokinetics of bevacizumab in haemodialysis
    • Garnier-Viougeat, N. et al. Pharmacokinetics of bevacizumab in haemodialysis. Nephrol. Dial. Transplant. 22, 975 (2007).
    • (2007) Nephrol. Dial. Transplant. , vol.22 , pp. 975
    • Garnier-Viougeat, N.1
  • 34
    • 84865331376 scopus 로고    scopus 로고
    • Use of tyrosine kinase inhibitors in patients with metastatic kidney cancer receiving haemodialysis: A retrospective Italian survey
    • Masini, C. et al. Use of tyrosine kinase inhibitors in patients with metastatic kidney cancer receiving haemodialysis: a retrospective Italian survey. BJU Int. 110, 692-698 (2012).
    • (2012) BJU Int. , vol.110 , pp. 692-698
    • Masini, C.1
  • 35
    • 84922599735 scopus 로고    scopus 로고
    • Outcomes of patients with metastatic renal cell carcinoma and end-stage renal disease receiving dialysis and targeted therapies: A single institution experience
    • Shetty, A. V. et al. Outcomes of patients with metastatic renal cell carcinoma and end-stage renal disease receiving dialysis and targeted therapies: a single institution experience. Clin. Genitourin. Cancer 12, 348-353 (2014).
    • (2014) Clin. Genitourin. Cancer , vol.12 , pp. 348-353
    • Shetty, A.V.1
  • 36
    • 67249141051 scopus 로고    scopus 로고
    • Sorafenib tosylate in advanced kidney cancer: Past, present and future
    • Porta, C., Paglino, C., Imarisio, I. & Ferraris, E. Sorafenib tosylate in advanced kidney cancer: past, present and future. Anticancer Drugs 20, 409-415 (2009).
    • (2009) Anticancer Drugs , vol.20 , pp. 409-415
    • Porta, C.1    Paglino, C.2    Imarisio, I.3    Ferraris, E.4
  • 37
    • 4944249117 scopus 로고    scopus 로고
    • BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
    • Wilhelm, S. M. et al. BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res. 64, 7099-7109 (2004).
    • (2004) Cancer Res. , vol.64 , pp. 7099-7109
    • Wilhelm, S.M.1
  • 38
    • 84891671103 scopus 로고    scopus 로고
    • Regorafenib: A novel multitargeted tyrosine kinase inhibitor for colorectal cancer and gastrointestinal stromal tumors
    • Crona, D. J., Keisler, M. D. & Walko, C. M. Regorafenib: a novel multitargeted tyrosine kinase inhibitor for colorectal cancer and gastrointestinal stromal tumors. Ann. Pharmacother. 47, 1685-1696 (2013).
    • (2013) Ann. Pharmacother. , vol.47 , pp. 1685-1696
    • Crona, D.J.1    Keisler, M.D.2    Walko, C.M.3
  • 39
    • 21244475061 scopus 로고    scopus 로고
    • ZD6474-a novel inhibitor of VEGFR and EGFR tyrosine kinase activity
    • Ryan, A. J. & Wedge, S. R. ZD6474-a novel inhibitor of VEGFR and EGFR tyrosine kinase activity. Br. J. Cancer 92 (Suppl. 1), S6-S13 (2005).
    • (2005) Br. J. Cancer , vol.92 , pp. S6-S13
    • Ryan, A.J.1    Wedge, S.R.2
  • 40
    • 79953301961 scopus 로고    scopus 로고
    • Sorafenib may induce hypophosphatemia through a fibroblast growth factor-23 (FGF23)-independent mechanism
    • Bellini, E. et al. Sorafenib may induce hypophosphatemia through a fibroblast growth factor-23 (FGF23)-independent mechanism. Ann. Oncol. 22, 988-990 (2011).
    • (2011) Ann. Oncol. , vol.22 , pp. 988-990
    • Bellini, E.1
  • 41
    • 84855177596 scopus 로고    scopus 로고
    • Sorafenib-induced diarrhea and hypophosphatemia: Mechanisms and therapeutic implications
    • Mir, O., Coriat, R., Boudou-Rouquette, P., Durand, J. P. & Goldwasser, F. Sorafenib-induced diarrhea and hypophosphatemia: mechanisms and therapeutic implications. Ann. Oncol. 23, 280-281 (2012).
    • (2012) Ann. Oncol. , vol.23 , pp. 280-281
    • Mir, O.1    Coriat, R.2    Boudou-Rouquette, P.3    Durand, J.P.4    Goldwasser, F.5
  • 42
    • 84888611958 scopus 로고    scopus 로고
    • Assessment of vandetanib as an inhibitor of various human renal transporters: Inhibition of multidrug and toxin extrusion as a possible mechanism leading to decreased cisplatin and creatinine clearance
    • Shen, H., Yang, Z., Zhao, W., Zhang, Y. & Rodrigues, A. D. Assessment of vandetanib as an inhibitor of various human renal transporters: inhibition of multidrug and toxin extrusion as a possible mechanism leading to decreased cisplatin and creatinine clearance. Drug Metab. Dispos. 41, 2095-2103 (2013).
    • (2013) Drug Metab. Dispos. , vol.41 , pp. 2095-2103
    • Shen, H.1    Yang, Z.2    Zhao, W.3    Zhang, Y.4    Rodrigues, A.D.5
  • 44
    • 64649083367 scopus 로고    scopus 로고
    • Phase i and pharmacokinetic study of sorafenib in patients with hepatic or renal dysfunction: CALGB 60301
    • Miller, A. A. et al. Phase I and pharmacokinetic study of sorafenib in patients with hepatic or renal dysfunction: CALGB 60301. J. Clin. Oncol. 27, 1800-1805 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , pp. 1800-1805
    • Miller, A.A.1
  • 45
    • 70449379934 scopus 로고    scopus 로고
    • Safety and efficacy of sorafenib therapy in patients with metastatic kidney cancer with impaired renal function
    • Parsa, V., Heilbrun, L., Smith, D., Sethi, A. & Vaishampayan, U. Safety and efficacy of sorafenib therapy in patients with metastatic kidney cancer with impaired renal function. Clin. Genitourin. Cancer 7, E10-E15 (2009).
    • (2009) Clin. Genitourin. Cancer , vol.7 , pp. E10-E15
    • Parsa, V.1    Heilbrun, L.2    Smith, D.3    Sethi, A.4    Vaishampayan, U.5
  • 46
    • 77955248323 scopus 로고    scopus 로고
    • Sunitinib and sorafenib in metastatic renal cell carcinoma patients with renal insufficiency
    • Khan, G. et al. Sunitinib and sorafenib in metastatic renal cell carcinoma patients with renal insufficiency. Ann. Oncol. 21, 1618-1622 (2010).
    • (2010) Ann. Oncol. , vol.21 , pp. 1618-1622
    • Khan, G.1
  • 47
    • 70350076873 scopus 로고    scopus 로고
    • Use of sorafenib in two metastatic renal cell cancer patients with end-stage renal impairment undergoing replacement hemodialysis
    • Ferraris, E. et al. Use of sorafenib in two metastatic renal cell cancer patients with end-stage renal impairment undergoing replacement hemodialysis. Tumori 95, 542-544 (2009).
    • (2009) Tumori , vol.95 , pp. 542-544
    • Ferraris, E.1
  • 48
    • 79955829301 scopus 로고    scopus 로고
    • Clinical results and pharmacokinetics of sorafenib in chronic hemodialysis patients with metastatic renal cell carcinoma in a single center
    • Kennoki, T. et al. Clinical results and pharmacokinetics of sorafenib in chronic hemodialysis patients with metastatic renal cell carcinoma in a single center. Jpn. J. Clin. Oncol. 41, 647-655 (2011).
    • (2011) Jpn. J. Clin. Oncol. , vol.41 , pp. 647-655
    • Kennoki, T.1
  • 49
    • 77955454200 scopus 로고    scopus 로고
    • Pharmacokinetics of vandetanib in subjects with renal or hepatic impairment
    • Weil, A. et al. Pharmacokinetics of vandetanib in subjects with renal or hepatic impairment. Clin. Pharmacokinet. 49, 607-618 (2010).
    • (2010) Clin. Pharmacokinet. , vol.49 , pp. 607-618
    • Weil, A.1
  • 50
    • 0036769158 scopus 로고    scopus 로고
    • Pharmacology of imatinib (STI571)
    • Buchdunger, E., O'Reilly, T. & Wood, J. Pharmacology of imatinib (STI571). Eur. J. Cancer 38 (Suppl. 5), S28-S36 (2002).
    • (2002) Eur. J. Cancer , vol.38 , pp. S28-S36
    • Buchdunger, E.1    O'Reilly, T.2    Wood, J.3
  • 51
    • 84885365382 scopus 로고    scopus 로고
    • Tyrosine kinase inhibition by imatinib slows progression in chronic ant-thy1 glomerulosclerosis of the rat
    • Wang-Rosenke, Y. et al. Tyrosine kinase inhibition by imatinib slows progression in chronic ant-thy1 glomerulosclerosis of the rat. BMC Nephrol. 14, 223 (2013).
    • (2013) BMC Nephrol. , vol.14 , pp. 223
    • Wang-Rosenke, Y.1
  • 52
    • 84877630186 scopus 로고    scopus 로고
    • Antifibrotic effect after low-dose imatinib mesylate treatment in patients with nephrogenic systemic fibrosis: An open-label non-randomized, uncontrolled clinical trial
    • Elmholdt, T. R., Buus, N. H., Ramsing, M. & Olesen, A. B. Antifibrotic effect after low-dose imatinib mesylate treatment in patients with nephrogenic systemic fibrosis: an open-label non-randomized, uncontrolled clinical trial. J. Eur. Acad. Dermatol. Venereol. 27, 779-784 (2013).
    • (2013) J. Eur. Acad. Dermatol. Venereol. , vol.27 , pp. 779-784
    • Elmholdt, T.R.1    Buus, N.H.2    Ramsing, M.3    Olesen, A.B.4
  • 53
    • 84877094679 scopus 로고    scopus 로고
    • Imatinib: Novel treatment of immune-mediated kidney injury
    • Wallace, E. & Gewin, L. Imatinib: novel treatment of immune-mediated kidney injury. J. Am. Soc. Nephrol. 24, 694-701 (2013).
    • (2013) J. Am. Soc. Nephrol. , vol.24 , pp. 694-701
    • Wallace, E.1    Gewin, L.2
  • 54
    • 83655191946 scopus 로고    scopus 로고
    • Imatinib therapy for non-infection-related type II cryoglobulinemia with membranoproliferative glomerulonephritis
    • Wallace, E., Fogo, A. B. & Schulman, G. Imatinib therapy for non-infection-related type II cryoglobulinemia with membranoproliferative glomerulonephritis. Am. J. Kidney Dis. 59, 122-125 (2012).
    • (2012) Am. J. Kidney Dis. , vol.59 , pp. 122-125
    • Wallace, E.1    Fogo, A.B.2    Schulman, G.3
  • 55
    • 57649153080 scopus 로고    scopus 로고
    • Imatinib in the treatment of nephrogenic systemic fibrosis
    • Chandran, S. et al. Imatinib in the treatment of nephrogenic systemic fibrosis. Am. J. Kidney Dis. 53, 129-132 (2009).
    • (2009) Am. J. Kidney Dis. , vol.53 , pp. 129-132
    • Chandran, S.1
  • 56
    • 79960953339 scopus 로고    scopus 로고
    • Early short-term imatinib treatment is sufficient to prevent the development of chronic allograft nephropathy
    • Savikko, J., Rintala, J. M., Rintala, S. E., Koskinen, P. K. & von Willebrand. E. Early short-term imatinib treatment is sufficient to prevent the development of chronic allograft nephropathy. Nephrol. Dial. Transplant. 26, 3026-3032 (2011).
    • (2011) Nephrol. Dial. Transplant. , vol.26 , pp. 3026-3032
    • Savikko, J.1    Rintala, J.M.2    Rintala, S.E.3    Koskinen, P.K.4    Von Willebrand., E.5
  • 57
    • 84874825720 scopus 로고    scopus 로고
    • Long and short-term treatment with imatinib attenuates the development of chronic kidney disease in experimental anti-glomerular basement membrane nephritis
    • Iyoda, M. et al. Long and short-term treatment with imatinib attenuates the development of chronic kidney disease in experimental anti-glomerular basement membrane nephritis. Nephrol. Dial. Transplant. 28, 576-584 (2013).
    • (2013) Nephrol. Dial. Transplant. , vol.28 , pp. 576-584
    • Iyoda, M.1
  • 58
    • 24344482346 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of imatinib
    • Peng, B., Lloyd, P. & Schran, H. Clinical pharmacokinetics of imatinib. Clin. Pharmacokinet. 44, 879-894 (2005).
    • (2005) Clin. Pharmacokinet. , vol.44 , pp. 879-894
    • Peng, B.1    Lloyd, P.2    Schran, H.3
  • 59
    • 39149099201 scopus 로고    scopus 로고
    • Phase i and pharmacokinetic study of imatinib mesylate in patients with advanced malignancies and varying degrees of renal dysfunction: A study by the National Cancer Institute Organ Dysfunction Working Group
    • Gibbons, J. et al. Phase I and pharmacokinetic study of imatinib mesylate in patients with advanced malignancies and varying degrees of renal dysfunction: a study by the National Cancer Institute Organ Dysfunction Working Group. J. Clin. Oncol. 26, 570-576 (2008).
    • (2008) J. Clin. Oncol. , vol.26 , pp. 570-576
    • Gibbons, J.1
  • 60
    • 39149102893 scopus 로고    scopus 로고
    • Imatinib for patients with liver or kidney dysfunction: No need to modify the dose
    • Judson, I. R. Imatinib for patients with liver or kidney dysfunction: no need to modify the dose. J. Clin. Oncol. 26, 521-522 (2008).
    • (2008) J. Clin. Oncol. , vol.26 , pp. 521-522
    • Judson, I.R.1
  • 61
    • 77954261761 scopus 로고    scopus 로고
    • Imatinib front-line therapy is safe and effective in patients with chronic myelogenous leukemia with pre-existing liver and/or renal dysfunction
    • Tong, W. G. et al. Imatinib front-line therapy is safe and effective in patients with chronic myelogenous leukemia with pre-existing liver and/or renal dysfunction. Cancer 116, 3152-3159 (2010).
    • (2010) Cancer , vol.116 , pp. 3152-3159
    • Tong, W.G.1
  • 62
    • 84883063380 scopus 로고    scopus 로고
    • Results of an international randomized phase III trial of the mammalian target of rapamycin inhibitor ridaforolimus versus placebo to control metastatic sarcomas in patients after benefit from prior chemotherapy
    • Demetri, G. D. et al. Results of an international randomized phase III trial of the mammalian target of rapamycin inhibitor ridaforolimus versus placebo to control metastatic sarcomas in patients after benefit from prior chemotherapy. J. Clin. Oncol. 31, 2485-2492 (2013).
    • (2013) J. Clin. Oncol. , vol.31 , pp. 2485-2492
    • Demetri, G.D.1
  • 63
    • 84901008792 scopus 로고    scopus 로고
    • Targeting PI3K/Akt/mTOR signaling in cancer
    • Porta, C., Paglino, C. & Mosca, A. Targeting PI3K/Akt/mTOR signaling in cancer. Front. Oncol. 4, 64 (2014).
    • (2014) Front. Oncol. , vol.4 , pp. 64
    • Porta, C.1    Paglino, C.2    Mosca, A.3
  • 64
    • 37349107870 scopus 로고    scopus 로고
    • The mTOR inhibitor everolimus induces proteinuria and renal deterioration in the remnant kidney model in the rat
    • Vogelbacher, R., Wittmann, S., Braun, A., Daniel, C. & Hugo, C. The mTOR inhibitor everolimus induces proteinuria and renal deterioration in the remnant kidney model in the rat. Transplantation 84, 1492-1499 (2007).
    • (2007) Transplantation , vol.84 , pp. 1492-1499
    • Vogelbacher, R.1    Wittmann, S.2    Braun, A.3    Daniel, C.4    Hugo, C.5
  • 65
    • 84881546173 scopus 로고    scopus 로고
    • Cyclosporine versus everolimus: Effects on the glomerulus
    • Baas, M. C. et al. Cyclosporine versus everolimus: effects on the glomerulus. Clin. Transplant. 27, 535-540 (2013).
    • (2013) Clin. Transplant. , vol.27 , pp. 535-540
    • Baas, M.C.1
  • 66
    • 33749618333 scopus 로고    scopus 로고
    • Everolimus inhibits glomerular endothelial cell proliferation and VEGF, but not long-term recovery in experimental thrombotic microangiopathy
    • Keller, K. et al. Everolimus inhibits glomerular endothelial cell proliferation and VEGF, but not long-term recovery in experimental thrombotic microangiopathy. Nephrol. Dial. Transplant. 21, 2724-2735 (2006).
    • (2006) Nephrol. Dial. Transplant. , vol.21 , pp. 2724-2735
    • Keller, K.1
  • 67
    • 84869091726 scopus 로고    scopus 로고
    • Involvement of autophagy in the pharmacological effects of the mTOR inhibitor everolimus in acute kidney injury
    • Nakagawa, S., Nishihara, K., Inui, K. & Masuda, S. Involvement of autophagy in the pharmacological effects of the mTOR inhibitor everolimus in acute kidney injury. Eur. J. Pharmacol. 696, 143-154 (2012).
    • (2012) Eur. J. Pharmacol. , vol.696 , pp. 143-154
    • Nakagawa, S.1    Nishihara, K.2    Inui, K.3    Masuda, S.4
  • 68
    • 33645751447 scopus 로고    scopus 로고
    • New drug application 21-628, Certican (everolimus), for the proposed indication of prophylaxis of rejection in heart transplantation: Report from the Cardiovascular and Renal Drugs Advisory Committee, US Food and Drug Administration, November 16, 2005, Rockville, Md
    • Cardiovascular and Renal Drugs Advisory Committee, US Food and Drug Administration
    • Hiatt, W. R., Nissen, S. E. & Cardiovascular and Renal Drugs Advisory Committee, US Food and Drug Administration. New drug application 21-628, Certican (everolimus), for the proposed indication of prophylaxis of rejection in heart transplantation: report from the Cardiovascular and Renal Drugs Advisory Committee, US Food and Drug Administration, November 16, 2005, Rockville, Md. Circulation 113, e394-e395 (2006).
    • (2006) Circulation , vol.113 , pp. e394-e395
    • Hiatt, W.R.1    Nissen, S.E.2
  • 69
    • 65549140131 scopus 로고    scopus 로고
    • Posttransplant proteinuria associated with everolimus
    • Bertoni, E. et al. Posttransplant proteinuria associated with everolimus. Transplant Proc. 41, 1216-1217 (2009).
    • (2009) Transplant Proc. , vol.41 , pp. 1216-1217
    • Bertoni, E.1
  • 70
    • 77953757715 scopus 로고    scopus 로고
    • Plethora of agents, plethora of targets, plethora of side effects in metastatic renal cell carcinoma
    • Schmidinger, M. & Bellmunt, J. Plethora of agents, plethora of targets, plethora of side effects in metastatic renal cell carcinoma. Cancer Treat. Rev. 36, 416-424 (2010).
    • (2010) Cancer Treat. Rev. , vol.36 , pp. 416-424
    • Schmidinger, M.1    Bellmunt, J.2
  • 71
    • 77953911869 scopus 로고    scopus 로고
    • Sirolimus and everolimus reduce albumin endocytosis in proximal tubule cells via an angiotensin II-dependent pathway
    • Oroszlán, M. et al. Sirolimus and everolimus reduce albumin endocytosis in proximal tubule cells via an angiotensin II-dependent pathway. Transpl. Immunol. 23, 125-132 (2010).
    • (2010) Transpl. Immunol. , vol.23 , pp. 125-132
    • Oroszlán, M.1
  • 72
    • 77951282223 scopus 로고    scopus 로고
    • Emergent toxicities associated with the use of mTOR inhibitors in patients with advanced renal carcinoma
    • Rodriguez-Pascual, J., Cheng, E., Maroto, P. & Duran, I. Emergent toxicities associated with the use of mTOR inhibitors in patients with advanced renal carcinoma. Anticancer Drugs 21, 478-486 (2010).
    • (2010) Anticancer Drugs , vol.21 , pp. 478-486
    • Rodriguez-Pascual, J.1    Cheng, E.2    Maroto, P.3    Duran, I.4
  • 73
    • 84884167903 scopus 로고    scopus 로고
    • MTOR inhibitors in advanced renal cell carcinomas: From biology to clinical practice
    • Barthélémy, P. et al. mTOR inhibitors in advanced renal cell carcinomas: from biology to clinical practice. Crit. Rev. Oncol. Hematol. 88, 42-56 (2013).
    • (2013) Crit. Rev. Oncol. Hematol. , vol.88 , pp. 42-56
    • Barthélémy, P.1
  • 74
    • 79957566962 scopus 로고    scopus 로고
    • Management of adverse events associated with the use of everolimus in patients with advanced renal cell carcinoma
    • Porta, C. et al. Management of adverse events associated with the use of everolimus in patients with advanced renal cell carcinoma. Eur. J. Cancer 47, 1287-1298 (2011).
    • (2011) Eur. J. Cancer , vol.47 , pp. 1287-1298
    • Porta, C.1
  • 75
    • 84897056068 scopus 로고    scopus 로고
    • Adverse event management in patients with advanced cancer receiving oral everolimus: Focus on breast cancer
    • Aapro, M. et al. Adverse event management in patients with advanced cancer receiving oral everolimus: focus on breast cancer. Ann. Oncol. 25, 763-773 (2014).
    • (2014) Ann. Oncol. , vol.25 , pp. 763-773
    • Aapro, M.1
  • 76
    • 84868139593 scopus 로고    scopus 로고
    • Hemodialysis does not affect everolimus pharmacokinetics: Two cases of patients with metastatic renal cell cancer
    • Thiery-Vuillemin, A. et al. Hemodialysis does not affect everolimus pharmacokinetics: two cases of patients with metastatic renal cell cancer. Ann. Oncol. 23, 2992-2993 (2012).
    • (2012) Ann. Oncol. , vol.23 , pp. 2992-2993
    • Thiery-Vuillemin, A.1
  • 78
    • 72149105604 scopus 로고    scopus 로고
    • Comparison of temsirolimus pharmacokinetics in patients with renal cell carcinoma not receiving dialysis and those receiving hemodialysis: A case series
    • Lunardi, G. et al. Comparison of temsirolimus pharmacokinetics in patients with renal cell carcinoma not receiving dialysis and those receiving hemodialysis: a case series. Clin. Ther. 31, 1812-1819 (2009).
    • (2009) Clin. Ther. , vol.31 , pp. 1812-1819
    • Lunardi, G.1
  • 79
    • 69949186250 scopus 로고    scopus 로고
    • Screening for epidermal growth factor receptor mutations in lung cancer
    • Rosell, R. et al. Screening for epidermal growth factor receptor mutations in lung cancer. N. Engl. J. Med. 361, 958-967 (2009).
    • (2009) N. Engl. J. Med. , vol.361 , pp. 958-967
    • Rosell, R.1
  • 80
    • 0036016088 scopus 로고    scopus 로고
    • Anti-epidermal growth factor receptor drugs in cancer therapy
    • Ciardiello, F. & Tortora, G. Anti-epidermal growth factor receptor drugs in cancer therapy. Expert Opin. Investig. Drugs 11, 755-768 (2002).
    • (2002) Expert Opin. Investig. Drugs , vol.11 , pp. 755-768
    • Ciardiello, F.1    Tortora, G.2
  • 81
    • 0347683487 scopus 로고    scopus 로고
    • TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption
    • Voets, T. et al. TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption. J. Biol. Chem. 279, 19-25 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 19-25
    • Voets, T.1
  • 82
    • 34547700632 scopus 로고    scopus 로고
    • Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia
    • Groenestege, W. M. et al. Impaired basolateral sorting of pro-EGF causes isolated recessive renal hypomagnesemia. J. Clin. Invest. 117, 2260-2267 (2007).
    • (2007) J. Clin. Invest. , vol.117 , pp. 2260-2267
    • Groenestege, W.M.1
  • 83
    • 33749034712 scopus 로고    scopus 로고
    • Cetuximab-induced hypomagnesemia in patients with colorectal cancer
    • Fakih, M. G., Wilding, G. & Lombardo, J. Cetuximab-induced hypomagnesemia in patients with colorectal cancer. Clin. Colorectal Cancer 6, 152-156 (2006).
    • (2006) Clin. Colorectal Cancer , vol.6 , pp. 152-156
    • Fakih, M.G.1    Wilding, G.2    Lombardo, J.3
  • 84
    • 34247224987 scopus 로고    scopus 로고
    • Magnesium wasting associated with epidermal-growth-factor receptor-targeting antibodies in colorectal cancer: A prospective study
    • Tejpar, S. et al. Magnesium wasting associated with epidermal-growth-factor receptor-targeting antibodies in colorectal cancer: a prospective study. Lancet Oncol. 8, 387-394 (2007).
    • (2007) Lancet Oncol. , vol.8 , pp. 387-394
    • Tejpar, S.1
  • 86
    • 75049084668 scopus 로고    scopus 로고
    • Electrolyte disorders related to EGFR-targeting drugs
    • Izzedine, H. et al. Electrolyte disorders related to EGFR-targeting drugs. Crit. Rev. Oncol. Hematol. 73, 213-219 (2010).
    • (2010) Crit. Rev. Oncol. Hematol. , vol.73 , pp. 213-219
    • Izzedine, H.1
  • 87
    • 38949156235 scopus 로고    scopus 로고
    • Management of anti-EGFR-targeting monoclonal antibody-induced hypomagnesemia
    • Fakih, M. G. Management of anti-EGFR-targeting monoclonal antibody-induced hypomagnesemia. Oncology 22, 74-76 (2008).
    • (2008) Oncology , vol.22 , pp. 74-76
    • Fakih, M.G.1
  • 88
    • 77956197039 scopus 로고    scopus 로고
    • Electrolyte and protein imbalance following anti-EGFR therapy in cancer patients: A comparative study
    • Maliakal, P. & Ledford. A. Electrolyte and protein imbalance following anti-EGFR therapy in cancer patients: a comparative study. Exp. Ther. Med. 1, 307-311 (2010).
    • (2010) Exp. Ther. Med. , vol.1 , pp. 307-311
    • Maliakal, P.1    Ledford, A.2
  • 89
    • 77955640313 scopus 로고    scopus 로고
    • Effects of the EGFR inhibitor erlotinib on magnesium handling
    • Dimke, H. et al. Effects of the EGFR inhibitor erlotinib on magnesium handling. J. Am. Soc. Nephrol. 21, 1309-1316 (2010).
    • (2010) J. Am. Soc. Nephrol. , vol.21 , pp. 1309-1316
    • Dimke, H.1
  • 90
    • 84856061237 scopus 로고    scopus 로고
    • Hypomagnesaemia and targeted anti-epidermal growth factor receptor (EGFR) agents
    • Costa, A., Tejpar, S., Prenen, H. & Van Cutsem, E. Hypomagnesaemia and targeted anti-epidermal growth factor receptor (EGFR) agents. Target. Oncol. 6, 227-233 (2011).
    • (2011) Target. Oncol. , vol.6 , pp. 227-233
    • Costa, A.1    Tejpar, S.2    Prenen, H.3    Van Cutsem, E.4
  • 91
    • 84903814243 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of cetuximab in a patient with renal dysfunction
    • Krens, L. L. et al. Pharmacokinetics and safety of cetuximab in a patient with renal dysfunction. Cancer Chemother. Pharmacol. 73, 1303-1306 (2014).
    • (2014) Cancer Chemother. Pharmacol. , vol.73 , pp. 1303-1306
    • Krens, L.L.1
  • 93
    • 84889252880 scopus 로고    scopus 로고
    • Colorectal cancer patient on maintenance dialysis successfully treated with cetuximab
    • Fontana, E., Pucci, F. & Ardizzoni, A. Colorectal cancer patient on maintenance dialysis successfully treated with cetuximab. Anticancer Drugs 25, 120-122 (2014).
    • (2014) Anticancer Drugs , vol.25 , pp. 120-122
    • Fontana, E.1    Pucci, F.2    Ardizzoni, A.3
  • 94
    • 84886027554 scopus 로고    scopus 로고
    • Antibody-dependent cellular cytotoxicity in patients on chronic hemodialysis
    • Koch, T. et al. Antibody-dependent cellular cytotoxicity in patients on chronic hemodialysis. Am. J. Nephrol. 38, 379-387 (2013).
    • (2013) Am. J. Nephrol. , vol.38 , pp. 379-387
    • Koch, T.1
  • 95
    • 13844272813 scopus 로고    scopus 로고
    • Safety profile of gefitinib in advanced non-small cell lung cancer elderly patients with chronic renal failure: Two clinical cases
    • Rossi, A. et al. Safety profile of gefitinib in advanced non-small cell lung cancer elderly patients with chronic renal failure: two clinical cases. Lung Cancer 47, 421-423 (2005).
    • (2005) Lung Cancer , vol.47 , pp. 421-423
    • Rossi, A.1
  • 96
    • 84897025626 scopus 로고    scopus 로고
    • Complete metabolic remission with gefitinib in a hemodialysis patient with bone metastases from non-small cell lung cancer
    • Del Conte, A. et al. Complete metabolic remission with gefitinib in a hemodialysis patient with bone metastases from non-small cell lung cancer. Anticancer Res. 34, 319-322 (2014).
    • (2014) Anticancer Res. , vol.34 , pp. 319-322
    • Del Conte, A.1
  • 97
    • 77951878714 scopus 로고    scopus 로고
    • Pharmacokinetics of erlotinib and its active metabolite OSI-420 in patients with non-small cell lung cancer and chronic renal failure who are undergoing hemodialysis
    • Togashi, Y. et al. Pharmacokinetics of erlotinib and its active metabolite OSI-420 in patients with non-small cell lung cancer and chronic renal failure who are undergoing hemodialysis. J. Thorac. Oncol. 5, 601-605 (2010).
    • (2010) J. Thorac. Oncol. , vol.5 , pp. 601-605
    • Togashi, Y.1
  • 98
    • 84906303119 scopus 로고    scopus 로고
    • Gefitinib and afatinib treatment in an advanced non-small cell lung cancer (NSCLC) patient undergoing hemodialysis
    • Bersanelli, M., Tiseo, M., Artioli, F., Lucchi, L. & Ardizzoni, A. Gefitinib and afatinib treatment in an advanced non-small cell lung cancer (NSCLC) patient undergoing hemodialysis. Anticancer Res. 34, 3185-3188 (2014).
    • (2014) Anticancer Res. , vol.34 , pp. 3185-3188
    • Bersanelli, M.1    Tiseo, M.2    Artioli, F.3    Lucchi, L.4    Ardizzoni, A.5
  • 99
    • 33745925864 scopus 로고    scopus 로고
    • BRAF somatic mutations in malignant melanoma and melanocytic naevi
    • Thomas, N. E. BRAF somatic mutations in malignant melanoma and melanocytic naevi. Melanoma Res. 16, 97-103 (2006).
    • (2006) Melanoma Res. , vol.16 , pp. 97-103
    • Thomas, N.E.1
  • 100
    • 12144289677 scopus 로고    scopus 로고
    • Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF
    • Wan, P. T. et al. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell 116, 855-867 (2004).
    • (2004) Cell , vol.116 , pp. 855-867
    • Wan, P.T.1
  • 101
    • 84885650463 scopus 로고    scopus 로고
    • Acute kidney injury in patients with severe rash on vemurafenib treatment for metastatic melanomas
    • Regnier-Rosencher, E. et al. Acute kidney injury in patients with severe rash on vemurafenib treatment for metastatic melanomas. Br. J. Dermatol. 169, 934-948 (2013).
    • (2013) Br. J. Dermatol. , vol.169 , pp. 934-948
    • Regnier-Rosencher, E.1
  • 102
    • 84903778501 scopus 로고    scopus 로고
    • Acute renal failure associated with the new BRAF inhibitor vemurafenib: A case series of 8 patients
    • Launay-Vacher, V. et al. Acute renal failure associated with the new BRAF inhibitor vemurafenib: a case series of 8 patients. Cancer 120, 2158-2163 (2014).
    • (2014) Cancer , vol.120 , pp. 2158-2163
    • Launay-Vacher, V.1
  • 103
    • 84891648456 scopus 로고    scopus 로고
    • Phase II trial (BREAK-2) of the BRAF inhibitor dabrafenib (GSK2118436) in patients with metastatic melanoma
    • Ascierto, P. A. et al. Phase II trial (BREAK-2) of the BRAF inhibitor dabrafenib (GSK2118436) in patients with metastatic melanoma. J. Clin. Oncol. 31, 3205-3211 (2013).
    • (2013) J. Clin. Oncol. , vol.31 , pp. 3205-3211
    • Ascierto, P.A.1
  • 104
    • 84864285704 scopus 로고    scopus 로고
    • Dabrafenib in BRAF-mutated metastatic melanoma: A multicentre, open-label, phase 3 randomised controlled trial
    • Hauschild, A. et al. Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial. Lancet 380, 358-365 (2012).
    • (2012) Lancet , vol.380 , pp. 358-365
    • Hauschild, A.1
  • 105
    • 84879922967 scopus 로고    scopus 로고
    • Novel cutaneous effects of combination chemotherapy with BRAF and MEK inhibitors: A report of two cases
    • Green, J. S., Norris, D. A. & Wisell, J. Novel cutaneous effects of combination chemotherapy with BRAF and MEK inhibitors: a report of two cases. Br. J. Dermatol. 169, 172-176 (2013).
    • (2013) Br. J. Dermatol. , vol.169 , pp. 172-176
    • Green, J.S.1    Norris, D.A.2    Wisell, J.3
  • 106
    • 84889068787 scopus 로고    scopus 로고
    • Safety and efficacy of vemurafenib in end stage renal failure
    • Iddawela, M. et al. Safety and efficacy of vemurafenib in end stage renal failure. BMC Cancer 13, 581 (2013).
    • (2013) BMC Cancer , vol.13 , pp. 581
    • Iddawela, M.1
  • 107
    • 84868224906 scopus 로고    scopus 로고
    • Combined BRAF and MEK inhibition in melanoma with BRAF v600 mutations
    • Flaherty, K. T. et al. Combined BRAF and MEK inhibition in melanoma with BRAF v600 mutations. N. Engl. J. Med. 367, 1694-1703 (2012).
    • (2012) N. Engl. J. Med. , vol.367 , pp. 1694-1703
    • Flaherty, K.T.1
  • 108
    • 0032895235 scopus 로고    scopus 로고
    • Trastuzumab, a recombinant DNA-derived humanized monoclonal antibody, a novel agent for the treatment of metastatic breast cancer
    • Goldenberg, M. M. Trastuzumab, a recombinant DNA-derived humanized monoclonal antibody, a novel agent for the treatment of metastatic breast cancer. Clin. Ther. 21, 309-318 (1999).
    • (1999) Clin. Ther. , vol.21 , pp. 309-318
    • Goldenberg, M.M.1
  • 109
    • 84875138083 scopus 로고    scopus 로고
    • HER2 dimerization inhibitor pertuzumab-mode of action and clinical data in breast cancer
    • Harbeck, N. et al. HER2 dimerization inhibitor pertuzumab-mode of action and clinical data in breast cancer. Breast Care (Basel) 8, 49-55 (2013).
    • (2013) Breast Care (Basel) , vol.8 , pp. 49-55
    • Harbeck, N.1
  • 110
    • 2942592008 scopus 로고    scopus 로고
    • Dual kinase inhibition in the treatment of breast cancer: Initial experience with the EGFR/ErbB-2 inhibitor lapatinib
    • Burris, H. A. 3rd. Dual kinase inhibition in the treatment of breast cancer: initial experience with the EGFR/ErbB-2 inhibitor lapatinib. Oncologist 9 (Suppl. 3), 10-15 (2004).
    • (2004) Oncologist , vol.9 , pp. 10-15
    • Burris, H.A.1
  • 111
    • 84875204170 scopus 로고    scopus 로고
    • Trastuzumab emtansine (T-DM1) for HER2-positive breast cancer
    • Boyraz, B. et al. Trastuzumab emtansine (T-DM1) for HER2-positive breast cancer. Curr. Med. Res. Opin. 29, 405-414 (2013).
    • (2013) Curr. Med. Res. Opin. , vol.29 , pp. 405-414
    • Boyraz, B.1
  • 112
    • 84866533887 scopus 로고    scopus 로고
    • Role of renal function on the development of cardiotoxicity associated with trastuzumab-based adjuvant chemotherapy for early breast cancer
    • Russo, G. et al. Role of renal function on the development of cardiotoxicity associated with trastuzumab-based adjuvant chemotherapy for early breast cancer. Intern. Emerg. Med. 7, 439-446 (2012).
    • (2012) Intern. Emerg. Med. , vol.7 , pp. 439-446
    • Russo, G.1
  • 113
    • 73949105921 scopus 로고    scopus 로고
    • Trastuzumab plus anastrozole versus anastrozole alone for the treatment of postmenopausal women with human epidermal growth factor receptor 2-positive, hormone receptor-positive metastatic breast cancer: Results from the randomized phase III TAnDEM study
    • Kaufman, B. et al. Trastuzumab plus anastrozole versus anastrozole alone for the treatment of postmenopausal women with human epidermal growth factor receptor 2-positive, hormone receptor-positive metastatic breast cancer: results from the randomized phase III TAnDEM study. J. Clin. Oncol. 27, 5529-5537 (2009).
    • (2009) J. Clin. Oncol. , vol.27 , pp. 5529-5537
    • Kaufman, B.1
  • 114
    • 80053539103 scopus 로고    scopus 로고
    • Adjuvant trastuzumab in HER2-positive breast cancer
    • Slamon, D. et al. Adjuvant trastuzumab in HER2-positive breast cancer. N. Engl. J. Med. 365, 1273-1283 (2011).
    • (2011) N. Engl. J. Med. , vol.365 , pp. 1273-1283
    • Slamon, D.1
  • 115
    • 77956262693 scopus 로고    scopus 로고
    • Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial
    • Bang, Y. J. et al. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet 376, 687-697 (2010).
    • (2010) Lancet , vol.376 , pp. 687-697
    • Bang, Y.J.1
  • 117
    • 84885995645 scopus 로고    scopus 로고
    • Lapatinib and renal impairment: A case report
    • Piacentini, F., Omarini, C. & Barbieri, E. Lapatinib and renal impairment: a case report. Tumori 99, e134-e135 (2013).
    • (2013) Tumori , vol.99 , pp. e134-e135
    • Piacentini, F.1    Omarini, C.2    Barbieri, E.3
  • 118
    • 84930047269 scopus 로고    scopus 로고
    • Control of cell proliferation in lupus nephritis: The role of miRNAs and HER2 [abstract]
    • Costa Reis, A. P., Russo, P., Gallucci, S. & Sullivan, K. E. Control of cell proliferation in lupus nephritis: the role of miRNAs and HER2 [abstract]. Arthritis Rheumatol. 66 (Suppl. S3), S194 (2014).
    • (2014) Arthritis Rheumatol. , vol.66 , pp. S194
    • Costa Reis, A.P.1    Russo, P.2    Gallucci, S.3    Sullivan, K.E.4
  • 119
    • 0028484545 scopus 로고
    • CTLA-4 can function as a negative regulator of T cell activation
    • Walunas, T. L. et al. CTLA-4 can function as a negative regulator of T cell activation. Immunity 1, 405-413 (1994).
    • (1994) Immunity , vol.1 , pp. 405-413
    • Walunas, T.L.1
  • 120
    • 33749242789 scopus 로고    scopus 로고
    • Involvement of drug-specific T cells in acute drug-induced interstitial nephritis
    • Spanou, Z. et al. Involvement of drug-specific T cells in acute drug-induced interstitial nephritis. J. Am. Soc. Nephrol. 17, 2919-2927 (2006).
    • (2006) J. Am. Soc. Nephrol. , vol.17 , pp. 2919-2927
    • Spanou, Z.1
  • 121
    • 84872339660 scopus 로고    scopus 로고
    • The price of tumor control: An analysis of rare side effects of anti-CTLA-4 therapy in metastatic melanoma from the ipilimumab network
    • Voskens, C. J. et al. The price of tumor control: an analysis of rare side effects of anti-CTLA-4 therapy in metastatic melanoma from the ipilimumab network. PLoS ONE 8, e53745 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e53745
    • Voskens, C.J.1
  • 122
    • 84904553412 scopus 로고    scopus 로고
    • Kidney injuries related to ipilimumab
    • Izzedine, H. et al. Kidney injuries related to ipilimumab. Invest. New Drugs 32, 769-773 (2014).
    • (2014) Invest. New Drugs , vol.32 , pp. 769-773
    • Izzedine, H.1
  • 123
    • 67650491041 scopus 로고    scopus 로고
    • Anti-CTLA4 antibody-induced lupus nephritis
    • Fadel, F., El Karoui, K. & Knebelmann, B. Anti-CTLA4 antibody-induced lupus nephritis. N. Engl. J. Med. 361, 211-212 (2009).
    • (2009) N. Engl. J. Med. , vol.361 , pp. 211-212
    • Fadel, F.1    El Karoui, K.2    Knebelmann, B.3
  • 124
    • 58049202334 scopus 로고    scopus 로고
    • Phase I/II study of ipilimumab for patients with metastatic melanoma
    • Weber, J. S. et al. Phase I/II study of ipilimumab for patients with metastatic melanoma. J. Clin. Oncol. 26, 5950-5956 (2008).
    • (2008) J. Clin. Oncol. , vol.26 , pp. 5950-5956
    • Weber, J.S.1
  • 125
    • 77955256254 scopus 로고    scopus 로고
    • Efficacy and safety of ipilimumab monotherapy in patients with pretreated advanced melanoma: A multicenter single-arm phase II study
    • O'Day, S. J. et al. Efficacy and safety of ipilimumab monotherapy in patients with pretreated advanced melanoma: a multicenter single-arm phase II study. Ann. Oncol. 21, 1712-1717 (2010).
    • (2010) Ann. Oncol. , vol.21 , pp. 1712-1717
    • O'Day, S.J.1
  • 126
    • 79959772576 scopus 로고    scopus 로고
    • Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
    • Robert, C. et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N. Engl. J. Med. 364, 2517-2526 (2011).
    • (2011) N. Engl. J. Med. , vol.364 , pp. 2517-2526
    • Robert, C.1
  • 127
    • 79952767398 scopus 로고    scopus 로고
    • Crizotinib, a small-molecule dual inhibitor of the c-Met and ALK receptor tyrosine kinases
    • Rodig, S. J. & Shapiro, G. I. Crizotinib, a small-molecule dual inhibitor of the c-Met and ALK receptor tyrosine kinases. Curr. Opin. Investig. Drugs 11, 1477-1490 (2010).
    • (2010) Curr. Opin. Investig. Drugs , vol.11 , pp. 1477-1490
    • Rodig, S.J.1    Shapiro, G.I.2
  • 128
    • 84866934606 scopus 로고    scopus 로고
    • Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: Updated results from a phase 1 study
    • Camidge, D. R. et al. Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 study. Lancet Oncol. 13, 1011-1019 (2012).
    • (2012) Lancet Oncol. , vol.13 , pp. 1011-1019
    • Camidge, D.R.1
  • 129
    • 84879071011 scopus 로고    scopus 로고
    • Crizotinib versus chemotherapy in advanced ALK-positive lung cancer
    • Shaw, A. T. et al. Crizotinib versus chemotherapy in advanced ALK-positive lung cancer. N. Engl. J. Med. 368, 2385-2394 (2013).
    • (2013) N. Engl. J. Med. , vol.368 , pp. 2385-2394
    • Shaw, A.T.1
  • 130
    • 77956344338 scopus 로고    scopus 로고
    • Development and approval of the trifunctional antibody catumaxomab (anti-EpCAM x anti-CD3) as a targeted cancer immunotherapy
    • Seimetz, D., Lindhofer, H. & Bokemeyer, C. Development and approval of the trifunctional antibody catumaxomab (anti-EpCAM x anti-CD3) as a targeted cancer immunotherapy. Cancer Treat Rev. 36, 458-467 (2010).
    • (2010) Cancer Treat Rev. , vol.36 , pp. 458-467
    • Seimetz, D.1    Lindhofer, H.2    Bokemeyer, C.3
  • 131
    • 84896718907 scopus 로고    scopus 로고
    • Drug-induced reduction in estimated glomerular filtration rate in patients with ALK-positive non-small cell lung cancer treated with the ALK inhibitor crizotinib
    • Brosnan, E. M. et al. Drug-induced reduction in estimated glomerular filtration rate in patients with ALK-positive non-small cell lung cancer treated with the ALK inhibitor crizotinib. Cancer 120, 664-674 (2014).
    • (2014) Cancer , vol.120 , pp. 664-674
    • Brosnan, E.M.1
  • 133
    • 84887022695 scopus 로고    scopus 로고
    • Acute kidney injury following crizotinib administration for non-small-cell lung carcinoma
    • Gastaud, L. et al. Acute kidney injury following crizotinib administration for non-small-cell lung carcinoma. Lung Cancer 82, 362-364 (2013).
    • (2013) Lung Cancer , vol.82 , pp. 362-364
    • Gastaud, L.1
  • 134
    • 84925721057 scopus 로고    scopus 로고
    • Development of renal cysts after crizotinib in advanced ALK-positive non-small-cell lung cancer
    • Lin, Y. T. et al. Development of renal cysts after crizotinib in advanced ALK-positive non-small-cell lung cancer. J. Thorac. Oncol. 9, 1720-1725 (2014).
    • (2014) J. Thorac. Oncol. , vol.9 , pp. 1720-1725
    • Lin, Y.T.1
  • 136
    • 77953033291 scopus 로고    scopus 로고
    • Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: Results of a pharmacokinetic/pharmacodynamic meta-analysis
    • Houk, B. E. et al. Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: results of a pharmacokinetic/pharmacodynamic meta-analysis. Cancer Chemother. Pharmacol. 66, 357-371 (2010).
    • (2010) Cancer Chemother. Pharmacol. , vol.66 , pp. 357-371
    • Houk, B.E.1
  • 137
    • 65649142017 scopus 로고    scopus 로고
    • A new equation to estimate glomerular filtration rate
    • Levey, A. S. et al. A new equation to estimate glomerular filtration rate. Ann. Intern. Med. 150, 604-612 (2009).
    • (2009) Ann. Intern. Med. , vol.150 , pp. 604-612
    • Levey, A.S.1
  • 138
    • 84873875042 scopus 로고    scopus 로고
    • Management of anticancer treatment in patients under chronic dialysis: Results of the multicentric CANDY (CANcer and DialYsis) study
    • Janus, N. et al. Management of anticancer treatment in patients under chronic dialysis: results of the multicentric CANDY (CANcer and DialYsis) study. Ann. Oncol. 24, 501-507 (2013).
    • (2013) Ann. Oncol. , vol.24 , pp. 501-507
    • Janus, N.1
  • 139
    • 64549104195 scopus 로고    scopus 로고
    • Tolerability of first-line therapy for metastatic renal cell carcinoma
    • Porta, C. & Szczylik, C. Tolerability of first-line therapy for metastatic renal cell carcinoma. Cancer Treat. Rev. 35, 297-307 (2009).
    • (2009) Cancer Treat. Rev. , vol.35 , pp. 297-307
    • Porta, C.1    Szczylik, C.2
  • 140
    • 84905819860 scopus 로고    scopus 로고
    • Onco-nephrology: An invitation to new field
    • Finkel, K. W. & Howard, S. C. Onco-nephrology: an invitation to new field. J. Clin. Oncol. 32, 2389-2390 (2014).
    • (2014) J. Clin. Oncol. , vol.32 , pp. 2389-2390
    • Finkel, K.W.1    Howard, S.C.2
  • 142
    • 33846638744 scopus 로고    scopus 로고
    • Risks of proteinuria and hypertension with bevacizumab, an antibody against vascular endothelial growth factor: Systematic review and meta-analysis
    • Zhu, X., Wu, S., Dahut, W. L. & Parikh, C. R. Risks of proteinuria and hypertension with bevacizumab, an antibody against vascular endothelial growth factor: systematic review and meta-analysis. Am. J. Kidney Dis. 49, 186-193 (2007).
    • (2007) Am. J. Kidney Dis. , vol.49 , pp. 186-193
    • Zhu, X.1    Wu, S.2    Dahut, W.L.3    Parikh, C.R.4
  • 143
    • 77955638572 scopus 로고    scopus 로고
    • Bevacizumab increases risk for severe proteinuria in cancer patients
    • Wu, S., Kim, C., Baer, L. & Zhu, X. Bevacizumab increases risk for severe proteinuria in cancer patients. J. Am. Soc. Nephrol. 21, 1381-1389 (2010).
    • (2010) J. Am. Soc. Nephrol. , vol.21 , pp. 1381-1389
    • Wu, S.1    Kim, C.2    Baer, L.3    Zhu, X.4
  • 144
    • 77951100677 scopus 로고    scopus 로고
    • Increased risk of high-grade hypertension with bevacizumab in cancer patients: A meta-analysis
    • Ranpura, V., Pulipati, B., Chu, D., Zhu, X. & Wu, S. Increased risk of high-grade hypertension with bevacizumab in cancer patients: a meta-analysis. Am. J. Hypert. 23, 160-168 (2010).
    • (2010) Am. J. Hypert. , vol.23 , pp. 160-168
    • Ranpura, V.1    Pulipati, B.2    Chu, D.3    Zhu, X.4    Wu, S.5
  • 145
    • 84867047384 scopus 로고    scopus 로고
    • Addition of aflibercept to fluorouracil, leucovorin and irinotecan improves survival in a phase III randomized trial in patients with metastatic colorectal cancer previously treated with an oxaliplatin-based regimen
    • Van Cutsem, E. et al. Addition of aflibercept to fluorouracil, leucovorin and irinotecan improves survival in a phase III randomized trial in patients with metastatic colorectal cancer previously treated with an oxaliplatin-based regimen. J. Clin. Oncol. 30, 3499-3506 (2012).
    • (2012) J. Clin. Oncol. , vol.30 , pp. 3499-3506
    • Van Cutsem, E.1
  • 146
    • 84898832060 scopus 로고    scopus 로고
    • Risk of hypertension in cancer patients treated with aflibercept: A systematic review and meta-analysis
    • Qi, W. X., Shen, Z., Tang, L. N. & Yao, Y. Risk of hypertension in cancer patients treated with aflibercept: a systematic review and meta-analysis. Clin. Drug Investig. 34, 231-240 (2014).
    • (2014) Clin. Drug Investig. , vol.34 , pp. 231-240
    • Qi, W.X.1    Shen, Z.2    Tang, L.N.3    Yao, Y.4
  • 147
    • 58149098429 scopus 로고    scopus 로고
    • Risk of hypertension and renal dysfunction with an angiogenesis inhibitor sunitinib: Systematic review and meta-analysis
    • Zhu, X., Stergiopoulos, K. & Wu, S. Risk of hypertension and renal dysfunction with an angiogenesis inhibitor sunitinib: systematic review and meta-analysis. Acta Oncol. 48, 9-17 (2009).
    • (2009) Acta Oncol. , vol.48 , pp. 9-17
    • Zhu, X.1    Stergiopoulos, K.2    Wu, S.3
  • 148
    • 84874117127 scopus 로고    scopus 로고
    • Incidence and risk of hypertension with pazopanib in patients with cancer: A meta-analysis
    • Qi, W. X. et al. Incidence and risk of hypertension with pazopanib in patients with cancer: a meta-analysis. Cancer Chemother. Pharmacol. 71, 431-439 (2013).
    • (2013) Cancer Chemother. Pharmacol. , vol.71 , pp. 431-439
    • Qi, W.X.1
  • 149
    • 84897970656 scopus 로고    scopus 로고
    • Risks of proteinuria associated with vascular endothelial growth factor receptor tyrosine kinase inhibitors in cancer patients: A systematic review and meta-analysis
    • Zhang, Z. F., Wang, T. Liu, L. H. & Guo, H. Q. Risks of proteinuria associated with vascular endothelial growth factor receptor tyrosine kinase inhibitors in cancer patients: a systematic review and meta-analysis. PLoS ONE 9, e90135 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e90135
    • Zhang, Z.F.1    Wang, T.2    Liu, L.H.3    Guo, H.Q.4
  • 150
    • 84882578238 scopus 로고    scopus 로고
    • Incidence and risk of hypertension with a novel multi-targeted kinase inhibitor axitinib in cancer patients: A systematic review and meta-analysis
    • Qi, W. X., He, A. N., Shen, Z. & Yao, Y. Incidence and risk of hypertension with a novel multi-targeted kinase inhibitor axitinib in cancer patients: a systematic review and meta-analysis. Br. J. Clin. Pharmacol. 76, 348-357 (2013).
    • (2013) Br. J. Clin. Pharmacol. , vol.76 , pp. 348-357
    • Qi, W.X.1    He, A.N.2    Shen, Z.3    Yao, Y.4
  • 151
    • 84896835575 scopus 로고    scopus 로고
    • Incidence and risk of Sorafenib-induced hypertension: A systematic review and meta-analysis J
    • Li, Y. et al. Incidence and risk of Sorafenib-induced hypertension: a systematic review and meta-analysis J. Clin. Hypertens. (Greenwich) 16, 177-185 (2014).
    • (2014) Clin. Hypertens. (Greenwich) , vol.16 , pp. 177-185
    • Li, Y.1
  • 152
    • 84884281930 scopus 로고    scopus 로고
    • Risk of hypertension in cancer patients treated with sorafenib: An updated systematic review and meta-analysis
    • Funakoshi, T., Latif, A. & Galsky, M. D. Risk of hypertension in cancer patients treated with sorafenib: an updated systematic review and meta-analysis. J. Hum. Hypertens. 27, 601-611 (2013).
    • (2013) J. Hum. Hypertens. , vol.27 , pp. 601-611
    • Funakoshi, T.1    Latif, A.2    Galsky, M.D.3
  • 153
    • 33846148701 scopus 로고    scopus 로고
    • Sorafenib in advanced clear-cell renal-cell carcinoma
    • Escudier, B. et al. Sorafenib in advanced clear-cell renal-cell carcinoma. N. Engl. J. Med. 356, 125-134 (2007).
    • (2007) N. Engl. J. Med. , vol.356 , pp. 125-134
    • Escudier, B.1
  • 154
    • 47949116252 scopus 로고    scopus 로고
    • Sorafenib in advanced hepatocellular carcinoma
    • Llovet, J. et al. Sorafenib in advanced hepatocellular carcinoma. N. Engl. J. Med. 359, 378-390 (2008).
    • (2008) N. Engl. J. Med. , vol.359 , pp. 378-390
    • Llovet, J.1
  • 155
    • 84872921660 scopus 로고    scopus 로고
    • Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): An international, multicentre, randomised, placebo-controlled, phase 3 trial
    • Grothey, A. et al. Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial. Lancet 381, 303-312 (2013).
    • (2013) Lancet , vol.381 , pp. 303-312
    • Grothey, A.1
  • 156
    • 48649107474 scopus 로고    scopus 로고
    • Efficacy of everolimus in advanced renal cell carcinoma: A double-blind, randomised, placebo-controlled phase III trial
    • Motzer, R. J. et al. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial. Lancet 372, 449-456 (2008).
    • (2008) Lancet , vol.372 , pp. 449-456
    • Motzer, R.J.1
  • 157
    • 79851500081 scopus 로고    scopus 로고
    • Everolimus for advanced pancreatic neuroendocrine tumors
    • Yao, J. C. et al. Everolimus for advanced pancreatic neuroendocrine tumors. N. Engl. J. Med. 364, 514-523 (2011).
    • (2011) N. Engl. J. Med. , vol.364 , pp. 514-523
    • Yao, J.C.1
  • 158
    • 84863078767 scopus 로고    scopus 로고
    • Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer
    • Baselga, J. et al. Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer. N. Engl. J. Med. 366, 520-529 (2012).
    • (2012) N. Engl. J. Med. , vol.366 , pp. 520-529
    • Baselga, J.1
  • 159
    • 34249779568 scopus 로고    scopus 로고
    • Temsirolimus, interferon, or both for advanced renal-cell carcinoma
    • Hudes, G. et al. Temsirolimus, interferon, or both for advanced renal-cell carcinoma. N. Engl. J. Med. 356, 2271-2781 (2007).
    • (2007) N. Engl. J. Med. , vol.356 , pp. 2271-2781
    • Hudes, G.1
  • 160
    • 84876483964 scopus 로고    scopus 로고
    • Incidence and risk of hypomagnesemia in advanced cancer patients treated with cetuximab: A meta-analysis
    • Chen, P., Wang, L., Li, H., Liu, B. & Zou, Z. Incidence and risk of hypomagnesemia in advanced cancer patients treated with cetuximab: a meta-analysis. Oncol. Lett. 5, 1915-1920 (2013).
    • (2013) Oncol. Lett. , vol.5 , pp. 1915-1920
    • Chen, P.1    Wang, L.2    Li, H.3    Liu, B.4    Zou, Z.5
  • 161
    • 78349268796 scopus 로고    scopus 로고
    • Meta-analysis of incidence and risk of hypomagnesemia with cetuximab for advanced cancer
    • Cao, Y., Liao, C., Tan, A., Liu, L. & Gao, F. Meta-analysis of incidence and risk of hypomagnesemia with cetuximab for advanced cancer. Chemotherapy 56, 459-465 (2010).
    • (2010) Chemotherapy , vol.56 , pp. 459-465
    • Cao, Y.1    Liao, C.2    Tan, A.3    Liu, L.4    Gao, F.5
  • 162
    • 84858695125 scopus 로고    scopus 로고
    • Risk of anti-EGFR monoclonal antibody-related hypomagnesemia: Systematic review and pooled analysis of randomized studies
    • Petrelli, F., Borgonovo, K., Cabiddu, M., Ghilardi, M. & Barni, S. Risk of anti-EGFR monoclonal antibody-related hypomagnesemia: systematic review and pooled analysis of randomized studies. Expert Opin. Drug Saf. 11 (Suppl. 1), S9-19 (2012).
    • (2012) Expert Opin. Drug Saf. , vol.11 , pp. S9-19
    • Petrelli, F.1    Borgonovo, K.2    Cabiddu, M.3    Ghilardi, M.4    Barni, S.5
  • 163
    • 77951885057 scopus 로고    scopus 로고
    • Meta-analysis of incidence and risk of hypokalemia with cetuximab-based therapy for advanced cancer
    • Cao, Y., Liu, L., Liao, C., Tan, A. & Gao, F. Meta-analysis of incidence and risk of hypokalemia with cetuximab-based therapy for advanced cancer. Cancer Chemother. Pharmacol. 66, 37-42 (2010).
    • (2010) Cancer Chemother. Pharmacol. , vol.66 , pp. 37-42
    • Cao, Y.1    Liu, L.2    Liao, C.3    Tan, A.4    Gao, F.5
  • 164
    • 56249109644 scopus 로고    scopus 로고
    • Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): A randomised phase III trial
    • Kim, E. S. et al. Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): a randomised phase III trial. Lancet 372, 1809-1818 (2008).
    • (2008) Lancet , vol.372 , pp. 1809-1818
    • Kim, E.S.1
  • 165
    • 33749175953 scopus 로고    scopus 로고
    • Acute renal failure associated with gefitinib therapy
    • Wan, H. L. & Yao, N. S. Acute renal failure associated with gefitinib therapy. Lung 184, 249-250 (2006).
    • (2006) Lung , vol.184 , pp. 249-250
    • Wan, H.L.1    Yao, N.S.2
  • 166
    • 2942718938 scopus 로고    scopus 로고
    • Side effects of therapy: Case 1. Nephrotic syndrome associated with gefitinib therapy
    • Kumasaka, R. et al. Side effects of therapy: case 1. Nephrotic syndrome associated with gefitinib therapy. Clin. Oncol. 22, 2504-2505 (2004).
    • (2004) Clin. Oncol. , vol.22 , pp. 2504-2505
    • Kumasaka, R.1
  • 167
    • 84862785051 scopus 로고    scopus 로고
    • Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): A phase 2b/3 randomised trial
    • Miller, V. A. et al. Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/3 randomised trial. Lancet Oncol. 13, 528-538 (2012).
    • (2012) Lancet Oncol. , vol.13 , pp. 528-538
    • Miller, V.A.1


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