메뉴 건너뛰기




Volumn 34, Issue 4, 2014, Pages 231-240

Risk of hypertension in cancer patients treated with aflibercept: A systematic review and meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

AFLIBERCEPT; ANTINEOPLASTIC AGENT; BEVACIZUMAB; HYBRID PROTEIN; MONOCLONAL ANTIBODY; VASCULOTROPIN RECEPTOR;

EID: 84898832060     PISSN: 11732563     EISSN: 11791918     Source Type: Journal    
DOI: 10.1007/s40261-014-0174-5     Document Type: Review
Times cited : (55)

References (48)
  • 1
    • 4143136640 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Basic science and clinical progress
    • 15294883 10.1210/er.2003-0027
    • Ferrara N. Vascular endothelial growth factor: basic science and clinical progress. Endocr Rev. 2004;25(4):581-611.
    • (2004) Endocr Rev. , vol.25 , Issue.4 , pp. 581-611
    • Ferrara, N.1
  • 2
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • 11001068 10.1038/35025220
    • Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature. 2000;407(6801):249-57.
    • (2000) Nature. , vol.407 , Issue.6801 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 3
    • 69849111795 scopus 로고    scopus 로고
    • Aflibercept in epithelial ovarian carcinoma
    • 2744352 19519199 10.2217/fon.09.35
    • Moroney JW, Sood AK, Coleman RL. Aflibercept in epithelial ovarian carcinoma. Future Oncol. 2009;5(5):591-600.
    • (2009) Future Oncol. , vol.5 , Issue.5 , pp. 591-600
    • Moroney, J.W.1    Sood, A.K.2    Coleman, R.L.3
  • 4
    • 84861190138 scopus 로고    scopus 로고
    • A preclinical and clinical review of aflibercept for the management of cancer
    • 22264850 10.1016/j.ctrv.2011.12.008
    • Gaya A, Tse V. A preclinical and clinical review of aflibercept for the management of cancer. Cancer Treat Rev. 2012;38(5):484-93.
    • (2012) Cancer Treat Rev. , vol.38 , Issue.5 , pp. 484-493
    • Gaya, A.1    Tse, V.2
  • 6
    • 79952740612 scopus 로고    scopus 로고
    • Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma
    • 3048093 21321221 10.1073/pnas.1014480108
    • Keunen O, Johansson M, Oudin A, Sanzey M, Rahim SA, Fack F, et al. Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma. Proc Natl Acad Sci U S A. 2011;108(9):3749-54.
    • (2011) Proc Natl Acad Sci U S A. , vol.108 , Issue.9 , pp. 3749-3754
    • Keunen, O.1    Johansson, M.2    Oudin, A.3    Sanzey, M.4    Rahim, S.A.5    Fack, F.6
  • 7
    • 84898828433 scopus 로고    scopus 로고
    • ZALTRAP® (ziv-aflibercept). Regeneron Pharmaceuticals, Inc. Accessed Aug 2013
    • ZALTRAP® (ziv-aflibercept). Regeneron Pharmaceuticals, Inc. 2012. http://www.regeneron.com/zaltrap/zaltrap-fpi.pdf. Accessed Aug 2013.
    • (2012)
  • 9
    • 84867047384 scopus 로고    scopus 로고
    • Addition of aflibercept to fluorouracil, leucovorin, and irinotecan improves survival in a phase III randomized trial in patients with metastatic colorectal cancer previously treated with an oxaliplatin-based regimen
    • 22949147 10.1200/JCO.2012.42.8201
    • Van Cutsem E, Tabernero J, Lakomy R, Prenen H, Prausova J, Macarulla T, et al. Addition of aflibercept to fluorouracil, leucovorin, and irinotecan improves survival in a phase III randomized trial in patients with metastatic colorectal cancer previously treated with an oxaliplatin-based regimen. J Clin Oncol. 2012;30(28):3499-506.
    • (2012) J Clin Oncol. , vol.30 , Issue.28 , pp. 3499-3506
    • Van Cutsem, E.1    Tabernero, J.2    Lakomy, R.3    Prenen, H.4    Prausova, J.5    Macarulla, T.6
  • 10
    • 84879786803 scopus 로고    scopus 로고
    • Aflibercept versus placebo in combination with docetaxel and prednisone for treatment of men with metastatic castration-resistant prostate cancer (VENICE): A phase 3, double-blind randomised trial
    • 23742877 10.1016/S1470-2045(13)70184-0
    • Tannock IF, Fizazi K, Ivanov S, Karlsson CT, Flechon A, Skoneczna I, et al. Aflibercept versus placebo in combination with docetaxel and prednisone for treatment of men with metastatic castration-resistant prostate cancer (VENICE): a phase 3, double-blind randomised trial. Lancet Oncol. 2013;14(8):760-8.
    • (2013) Lancet Oncol. , vol.14 , Issue.8 , pp. 760-768
    • Tannock, I.F.1    Fizazi, K.2    Ivanov, S.3    Karlsson, C.T.4    Flechon, A.5    Skoneczna, I.6
  • 11
    • 84879952361 scopus 로고    scopus 로고
    • Randomised, placebo-controlled, double-blind, parallel-group phase III study evaluating aflibercept in patients receiving first-line treatment with gemcitabine for metastatic pancreatic cancer
    • 23642329 10.1016/j.ejca.2013.04.002
    • Rougier P, Riess H, Manges R, Karasek P, Humblet Y, Barone C, et al. Randomised, placebo-controlled, double-blind, parallel-group phase III study evaluating aflibercept in patients receiving first-line treatment with gemcitabine for metastatic pancreatic cancer. Eur J Cancer. 2013;49(12):2633-42.
    • (2013) Eur J Cancer. , vol.49 , Issue.12 , pp. 2633-2642
    • Rougier, P.1    Riess, H.2    Manges, R.3    Karasek, P.4    Humblet, Y.5    Barone, C.6
  • 12
    • 84867602821 scopus 로고    scopus 로고
    • Aflibercept and docetaxel versus docetaxel alone after platinum failure in patients with advanced or metastatic non-small-cell lung cancer: A randomized, controlled phase III trial
    • 22965962 10.1200/JCO.2012.42.6932
    • Ramlau R, Gorbunova V, Ciuleanu TE, Novello S, Ozguroglu M, Goksel T, et al. Aflibercept and docetaxel versus docetaxel alone after platinum failure in patients with advanced or metastatic non-small-cell lung cancer: a randomized, controlled phase III trial. J Clin Oncol. 2012;30(29):3640-7.
    • (2012) J Clin Oncol. , vol.30 , Issue.29 , pp. 3640-3647
    • Ramlau, R.1    Gorbunova, V.2    Ciuleanu, T.E.3    Novello, S.4    Ozguroglu, M.5    Goksel, T.6
  • 13
    • 77951100677 scopus 로고    scopus 로고
    • Increased risk of high-grade hypertension with bevacizumab in cancer patients: A meta-analysis
    • 20186127 10.1038/ajh.2010.25
    • Ranpura V, Pulipati B, Chu D, Zhu X, Wu S. Increased risk of high-grade hypertension with bevacizumab in cancer patients: a meta-analysis. Am J Hypertens. 2010;23(5):460-8.
    • (2010) Am J Hypertens. , vol.23 , Issue.5 , pp. 460-468
    • Ranpura, V.1    Pulipati, B.2    Chu, D.3    Zhu, X.4    Wu, S.5
  • 14
    • 84868667483 scopus 로고    scopus 로고
    • Incidence and risk of hypertension with vandetanib in cancer patients: A systematic review and meta-analysis of clinical trials
    • 22882307 10.1111/j.1365-2125.2012.04417.x
    • Qi WX, Shen Z, Lin F, Sun YJ, Min DL, Tang LN, et al. Incidence and risk of hypertension with vandetanib in cancer patients: a systematic review and meta-analysis of clinical trials. Br J Clin Pharmacol. 2013;75(4):919-30.
    • (2013) Br J Clin Pharmacol. , vol.75 , Issue.4 , pp. 919-930
    • Qi, W.X.1    Shen, Z.2    Lin, F.3    Sun, Y.J.4    Min, D.L.5    Tang, L.N.6
  • 15
    • 84876142760 scopus 로고    scopus 로고
    • Risk of venous thromboembolic events associated with VEGFR-TKIs: A systematic review and meta-analysis
    • 23225494 10.1002/ijc.27979
    • Qi WX, Min DL, Shen Z, Sun YJ, Lin F, Tang LN, et al. Risk of venous thromboembolic events associated with VEGFR-TKIs: a systematic review and meta-analysis. Int J Cancer. 2013;132(12):2967-74.
    • (2013) Int J Cancer. , vol.132 , Issue.12 , pp. 2967-2974
    • Qi, W.X.1    Min, D.L.2    Shen, Z.3    Sun, Y.J.4    Lin, F.5    Tang, L.N.6
  • 16
    • 84874117127 scopus 로고    scopus 로고
    • Incidence and risk of hypertension with pazopanib in patients with cancer: A meta-analysis
    • 23178953 10.1007/s00280-012-2025-5
    • Qi WX, Lin F, Sun YJ, Tang LN, He AN, Yao Y, et al. Incidence and risk of hypertension with pazopanib in patients with cancer: a meta-analysis. Cancer Chemother Pharmacol. 2013;71(2):431-9.
    • (2013) Cancer Chemother Pharmacol. , vol.71 , Issue.2 , pp. 431-439
    • Qi, W.X.1    Lin, F.2    Sun, Y.J.3    Tang, L.N.4    He, A.N.5    Yao, Y.6
  • 17
    • 84882578238 scopus 로고    scopus 로고
    • Incidence and risk of hypertension with a novel multi-targeted kinase inhibitor axitinib in cancer patients: A systematic review and meta-analysis
    • 23617405 10.1111/bcp.12149
    • Qi WX, He AN, Shen Z, Yao Y. Incidence and risk of hypertension with a novel multi-targeted kinase inhibitor axitinib in cancer patients: a systematic review and meta-analysis. Br J Clin Pharmacol. 2013;76(3):348-57.
    • (2013) Br J Clin Pharmacol. , vol.76 , Issue.3 , pp. 348-357
    • Qi, W.X.1    He, A.N.2    Shen, Z.3    Yao, Y.4
  • 18
    • 78049382933 scopus 로고    scopus 로고
    • Increased risk of serious hemorrhage with bevacizumab in cancer patients: A meta-analysis
    • 21051914 10.1159/000314980
    • Hapani S, Sher A, Chu D, Wu S. Increased risk of serious hemorrhage with bevacizumab in cancer patients: a meta-analysis. Oncology. 2010;79(1-2):27-38.
    • (2010) Oncology. , vol.79 , Issue.1-2 , pp. 27-38
    • Hapani, S.1    Sher, A.2    Chu, D.3    Wu, S.4
  • 19
    • 38549085315 scopus 로고    scopus 로고
    • Incidence and risk of hypertension with sorafenib in patients with cancer: A systematic review and meta-analysis
    • 18221915 10.1016/S1470-2045(08)70003-2
    • Wu S, Chen JJ, Kudelka A, Lu J, Zhu X. Incidence and risk of hypertension with sorafenib in patients with cancer: a systematic review and meta-analysis. Lancet Oncol. 2008;9(2):117-23.
    • (2008) Lancet Oncol. , vol.9 , Issue.2 , pp. 117-123
    • Wu, S.1    Chen, J.J.2    Kudelka, A.3    Lu, J.4    Zhu, X.5
  • 20
    • 56649123212 scopus 로고    scopus 로고
    • Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: A meta-analysis
    • 19017914 10.1001/jama.2008.656
    • Nalluri SR, Chu D, Keresztes R, Zhu X, Wu S. Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: a meta-analysis. JAMA. 2008;300(19):2277-85.
    • (2008) JAMA , vol.300 , Issue.19 , pp. 2277-2285
    • Nalluri, S.R.1    Chu, D.2    Keresztes, R.3    Zhu, X.4    Wu, S.5
  • 21
    • 34548141828 scopus 로고    scopus 로고
    • Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumab
    • 17686822 10.1093/jnci/djm086
    • Scappaticci FA, Skillings JR, Holden SN, Gerber HP, Miller K, Kabbinavar F, et al. Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumab. J Natl Cancer Inst. 2007;99(16):1232-9.
    • (2007) J Natl Cancer Inst. , vol.99 , Issue.16 , pp. 1232-1239
    • Scappaticci, F.A.1    Skillings, J.R.2    Holden, S.N.3    Gerber, H.P.4    Miller, K.5    Kabbinavar, F.6
  • 22
    • 84884281930 scopus 로고    scopus 로고
    • Risk of hypertension in cancer patients treated with sorafenib: An updated systematic review and meta-analysis
    • Funakoshi T, Latif A, Galsky MD. Risk of hypertension in cancer patients treated with sorafenib: an updated systematic review and meta-analysis. J Hum Hypertens. 2013;27(10):601-11.
    • (2013) J Hum Hypertens , vol.27 , Issue.10 , pp. 601-611
    • Funakoshi, T.1    Latif, A.2    Galsky, M.D.3
  • 23
    • 58149098429 scopus 로고    scopus 로고
    • Risk of hypertension and renal dysfunction with an angiogenesis inhibitor sunitinib: Systematic review and meta-analysis
    • 18752081 10.1080/02841860802314720
    • Zhu X, Stergiopoulos K, Wu S. Risk of hypertension and renal dysfunction with an angiogenesis inhibitor sunitinib: systematic review and meta-analysis. Acta Oncol. 2009;48(1):9-17.
    • (2009) Acta Oncol. , vol.48 , Issue.1 , pp. 9-17
    • Zhu, X.1    Stergiopoulos, K.2    Wu, S.3
  • 24
    • 84888793629 scopus 로고    scopus 로고
    • Incidence and risk of hemorrhagic events with vascular endothelial growth factor receptor tyrosine-kinase inhibitors: An up-to-date meta-analysis of 27 randomized controlled trials
    • 23921791 10.1093/annonc/mdt292
    • Qi WX, Tang LN, Sun YJ, He AN, Lin F, Shen Z, et al. Incidence and risk of hemorrhagic events with vascular endothelial growth factor receptor tyrosine-kinase inhibitors: an up-to-date meta-analysis of 27 randomized controlled trials. Ann Oncol. 2013;24(12):2943-52.
    • (2013) Ann Oncol. , vol.24 , Issue.12 , pp. 2943-2952
    • Qi, W.X.1    Tang, L.N.2    Sun, Y.J.3    He, A.N.4    Lin, F.5    Shen, Z.6
  • 25
    • 84896494847 scopus 로고    scopus 로고
    • Risk of gastrointestinal perforation in cancer patients treated with vascular endothelial growth factor receptor tyrosine kinase inhibitors: A systematic review and meta-analysis
    • Epub Oct 12
    • Qi WX, Sun YJ, Tang LN, Shen Z, Yao Y. Risk of gastrointestinal perforation in cancer patients treated with vascular endothelial growth factor receptor tyrosine kinase inhibitors: a systematic review and meta-analysis. Crit Rev Oncol Hematol. Epub 2013 Oct 12.
    • (2013) Crit Rev Oncol Hematol
    • Qi, W.X.1    Sun, Y.J.2    Tang, L.N.3    Shen, Z.4    Yao, Y.5
  • 26
    • 66149121478 scopus 로고    scopus 로고
    • Risk of gastrointestinal perforation in patients with cancer treated with bevacizumab: A meta-analysis
    • 19482548 10.1016/S1470-2045(09)70112-3
    • Hapani S, Chu D, Wu S. Risk of gastrointestinal perforation in patients with cancer treated with bevacizumab: a meta-analysis. Lancet Oncol. 2009;10(6):559-68.
    • (2009) Lancet Oncol. , vol.10 , Issue.6 , pp. 559-568
    • Hapani, S.1    Chu, D.2    Wu, S.3
  • 27
    • 84868527016 scopus 로고    scopus 로고
    • Phase II clinical and pharmacokinetic study of aflibercept in patients with previously treated metastatic colorectal cancer
    • 22977191 10.1158/1078-0432.CCR-11-3252
    • Tang PA, Cohen SJ, Kollmannsberger C, Bjarnason G, Virik K, MacKenzie MJ, et al. Phase II clinical and pharmacokinetic study of aflibercept in patients with previously treated metastatic colorectal cancer. Clin Cancer Res. 2012;18(21):6023-31.
    • (2012) Clin Cancer Res. , vol.18 , Issue.21 , pp. 6023-6031
    • Tang, P.A.1    Cohen, S.J.2    Kollmannsberger, C.3    Bjarnason, G.4    Virik, K.5    Mackenzie, M.J.6
  • 28
    • 84856509199 scopus 로고    scopus 로고
    • Intravenous aflibercept for treatment of recurrent symptomatic malignant ascites in patients with advanced ovarian cancer: A phase 2, randomised, double-blind, placebo-controlled study
    • 22192729 10.1016/S1470-2045(11)70338-2
    • Gotlieb WH, Amant F, Advani S, Goswami C, Hirte H, Provencher D, et al. Intravenous aflibercept for treatment of recurrent symptomatic malignant ascites in patients with advanced ovarian cancer: a phase 2, randomised, double-blind, placebo-controlled study. Lancet Oncol. 2012;13(2):154-62.
    • (2012) Lancet Oncol. , vol.13 , Issue.2 , pp. 154-162
    • Gotlieb, W.H.1    Amant, F.2    Advani, S.3    Goswami, C.4    Hirte, H.5    Provencher, D.6
  • 30
    • 2342661718 scopus 로고    scopus 로고
    • What to add to nothing? Use and avoidance of continuity corrections in meta-analysis of sparse data
    • 15116347 10.1002/sim.1761
    • Sweeting MJ, Sutton AJ, Lambert PC. What to add to nothing? Use and avoidance of continuity corrections in meta-analysis of sparse data. Stat Med. 2004;23(9):1351-75.
    • (2004) Stat Med. , vol.23 , Issue.9 , pp. 1351-1375
    • Sweeting, M.J.1    Sutton, A.J.2    Lambert, P.C.3
  • 31
    • 12744274510 scopus 로고    scopus 로고
    • Heterogeneity testing in meta-analysis of genome searches
    • 15593093 10.1002/gepi.20048
    • Zintzaras E, Ioannidis JP. Heterogeneity testing in meta-analysis of genome searches. Genet Epidemiol. 2005;28(2):123-37.
    • (2005) Genet Epidemiol. , vol.28 , Issue.2 , pp. 123-137
    • Zintzaras, E.1    Ioannidis, J.P.2
  • 32
    • 84879089369 scopus 로고    scopus 로고
    • The risk of hand-foot skin reaction to axitinib, a novel VEGF inhibitor: A systematic review of literature and meta-analysis
    • Fischer A, Wu S, Ho AL, Lacouture ME. The risk of hand-foot skin reaction to axitinib, a novel VEGF inhibitor: a systematic review of literature and meta-analysis. Invest New Drugs. 2013;31(3):787-97.
    • (2013) Invest New Drugs , vol.31 , Issue.3 , pp. 787-797
    • Fischer, A.1    Wu, S.2    Ho, A.L.3    Lacouture, M.E.4
  • 33
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • 2127453 9310563 10.1136/bmj.315.7109.629
    • Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315(7109):629-34.
    • (1997) BMJ , vol.315 , Issue.7109 , pp. 629-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3    Minder, C.4
  • 34
    • 0032558314 scopus 로고    scopus 로고
    • Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses?
    • 9746022 10.1016/S0140-6736(98)01085-X
    • Moher D, Pham B, Jones A, Cook DJ, Jadad AR, Moher M, et al. Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses? Lancet. 1998;352(9128):609-13.
    • (1998) Lancet. , vol.352 , Issue.9128 , pp. 609-613
    • Moher, D.1    Pham, B.2    Jones, A.3    Cook, D.J.4    Jadad, A.R.5    Moher, M.6
  • 35
    • 84858336778 scopus 로고    scopus 로고
    • A phase II study of aflibercept in patients with advanced epithelial ovarian cancer and symptomatic malignant ascites
    • 22112608 10.1016/j.ygyno.2011.11.021
    • Colombo N, Mangili G, Mammoliti S, Kalling M, Tholander B, Sternas L, et al. A phase II study of aflibercept in patients with advanced epithelial ovarian cancer and symptomatic malignant ascites. Gynecol Oncol. 2012;125(1):42-7.
    • (2012) Gynecol Oncol. , vol.125 , Issue.1 , pp. 42-47
    • Colombo, N.1    Mangili, G.2    Mammoliti, S.3    Kalling, M.4    Tholander, B.5    Sternas, L.6
  • 36
    • 80054097652 scopus 로고    scopus 로고
    • Aflibercept (VEGF Trap) in inoperable stage III or stage iv melanoma of cutaneous or uveal origin
    • 3196047 21880788 10.1158/1078-0432.CCR-11-1463
    • Tarhini AA, Frankel P, Margolin KA, Christensen S, Ruel C, Shipe-Spotloe J, et al. Aflibercept (VEGF Trap) in inoperable stage III or stage iv melanoma of cutaneous or uveal origin. Clin Cancer Res. 2011;17(20):6574-81.
    • (2011) Clin Cancer Res. , vol.17 , Issue.20 , pp. 6574-6581
    • Tarhini, A.A.1    Frankel, P.2    Margolin, K.A.3    Christensen, S.4    Ruel, C.5    Shipe-Spotloe, J.6
  • 37
    • 77950182626 scopus 로고    scopus 로고
    • Phase II study of aflibercept (VEGF trap) in recurrent inoperable stage III or stage IV melanoma of cutaneous or ocular origin
    • abstr 9028
    • Tarhini AA, Christensen S, Frankel P, Margolin K, Ruel C, Shipe-Spotloe J, et al. Phase II study of aflibercept (VEGF trap) in recurrent inoperable stage III or stage IV melanoma of cutaneous or ocular origin. J Clin Oncol. 2009;27(15):(suppl; abstr 9028).
    • (2009) J Clin Oncol , vol.27 , Issue.15 SUPPL.
    • Tarhini, A.A.1    Christensen, S.2    Frankel, P.3    Margolin, K.4    Ruel, C.5    Shipe-Spotloe, J.6
  • 38
    • 77954428008 scopus 로고    scopus 로고
    • A multicenter, phase 2 study of vascular endothelial growth factor trap (aflibercept) in platinum- and erlotinib-resistant adenocarcinoma of the lung
    • 20593550
    • Leighl NB, Raez LE, Besse B, Rosen PJ, Barlesi F, Massarelli E, et al. A multicenter, phase 2 study of vascular endothelial growth factor trap (aflibercept) in platinum- and erlotinib-resistant adenocarcinoma of the lung. J Thorac Oncol. 2010;5(7):1054-9.
    • (2010) J Thorac Oncol. , vol.5 , Issue.7 , pp. 1054-1059
    • Leighl, N.B.1    Raez, L.E.2    Besse, B.3    Rosen, P.J.4    Barlesi, F.5    Massarelli, E.6
  • 39
    • 77957068007 scopus 로고    scopus 로고
    • A phase II study of aflibercept (VEGF trap) in recurrent or metastatic gynecologic soft-tissue sarcomas: A study of the Princess Margaret Hospital Phase II Consortium
    • abstr 5591
    • Townsley C, Hirte H, Hoskins P, Buckanovich R, Mackay H, Welch S, et al. A phase II study of aflibercept (VEGF trap) in recurrent or metastatic gynecologic soft-tissue sarcomas: a study of the Princess Margaret Hospital Phase II Consortium. J Clin Oncol. 2009;27(15 s):(suppl; abstr 5591).
    • (2009) J Clin Oncol , vol.27 S , Issue.15 SUPPL.
    • Townsley, C.1    Hirte, H.2    Hoskins, P.3    Buckanovich, R.4    Mackay, H.5    Welch, S.6
  • 40
    • 84868588283 scopus 로고    scopus 로고
    • A phase II evaluation of aflibercept in the treatment of recurrent or persistent endometrial cancer: A Gynecologic Oncology Group study
    • 3568489 22922531 10.1016/j.ygyno.2012.08.020
    • Coleman RL, Sill MW, Lankes HA, Fader AN, Finkler NJ, Hoffman JS, et al. A phase II evaluation of aflibercept in the treatment of recurrent or persistent endometrial cancer: a Gynecologic Oncology Group study. Gynecol Oncol. 2012;127(3):538-43.
    • (2012) Gynecol Oncol. , vol.127 , Issue.3 , pp. 538-543
    • Coleman, R.L.1    Sill, M.W.2    Lankes, H.A.3    Fader, A.N.4    Finkler, N.J.5    Hoffman, J.S.6
  • 41
    • 79960111080 scopus 로고    scopus 로고
    • Phase II study of aflibercept in recurrent malignant glioma: A North American Brain Tumor Consortium study
    • 3139373 21606416 10.1200/JCO.2010.34.1636
    • de Groot JF, Lamborn KR, Chang SM, Gilbert MR, Cloughesy TF, Aldape K, et al. Phase II study of aflibercept in recurrent malignant glioma: a North American Brain Tumor Consortium study. J Clin Oncol. 2011;29(19):2689-95.
    • (2011) J Clin Oncol. , vol.29 , Issue.19 , pp. 2689-2695
    • De Groot, J.F.1    Lamborn, K.R.2    Chang, S.M.3    Gilbert, M.R.4    Cloughesy, T.F.5    Aldape, K.6
  • 42
    • 84858339404 scopus 로고    scopus 로고
    • A phase II study single agent of aflibercept (VEGF Trap) in patients with recurrent or metastatic gynecologic carcinosarcomas and uterine leiomyosarcoma. A trial of the Princess Margaret Hospital, Chicago and California Cancer Phase II Consortia
    • 3303987 22138373 10.1016/j.ygyno.2011.11.042
    • Mackay HJ, Buckanovich RJ, Hirte H, Correa R, Hoskins P, Biagi J, et al. A phase II study single agent of aflibercept (VEGF Trap) in patients with recurrent or metastatic gynecologic carcinosarcomas and uterine leiomyosarcoma. A trial of the Princess Margaret Hospital, Chicago and California Cancer Phase II Consortia. Gynecol Oncol. 2012;125(1):136-40.
    • (2012) Gynecol Oncol. , vol.125 , Issue.1 , pp. 136-140
    • Mackay, H.J.1    Buckanovich, R.J.2    Hirte, H.3    Correa, R.4    Hoskins, P.5    Biagi, J.6
  • 43
    • 77957756488 scopus 로고    scopus 로고
    • Phase II study of aflibercept (VEGF-Trap) in patients with recurrent or metastatic urothelial cancer, a California Cancer Consortium Trial
    • 2952720 20646741 10.1016/j.urology.2010.04.025
    • Twardowski P, Stadler WM, Frankel P, Lara PN, Ruel C, Chatta G, et al. Phase II study of aflibercept (VEGF-Trap) in patients with recurrent or metastatic urothelial cancer, a California Cancer Consortium Trial. Urology. 2010;76(4):923-6.
    • (2010) Urology. , vol.76 , Issue.4 , pp. 923-926
    • Twardowski, P.1    Stadler, W.M.2    Frankel, P.3    Lara, P.N.4    Ruel, C.5    Chatta, G.6
  • 44
    • 68049122102 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • Moher D, Liberati A, Tetzlaff J, Altman DG, Group P. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):e1000097.
    • (2009) PLoS Med , vol.6 , Issue.7
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4    Group, P.5
  • 45
    • 84877096642 scopus 로고    scopus 로고
    • Aflibercept
    • 3710732 23444216 10.1158/1078-0432.CCR-12-2911
    • Ciombor KK, Berlin J, Chan E. Aflibercept. Clin Cancer Res. 2013;19(8):1920-5.
    • (2013) Clin Cancer Res. , vol.19 , Issue.8 , pp. 1920-1925
    • Ciombor, K.K.1    Berlin, J.2    Chan, E.3
  • 47
    • 84866249108 scopus 로고    scopus 로고
    • Systemic thromboembolic adverse events in patients treated with intravitreal anti-VEGF drugs for neovascular age-related macular degeneration
    • 22866908 10.1517/14712598.2012.707176
    • Costagliola C, Agnifili L, Arcidiacono B, Duse S, Fasanella V, Mastropasqua R, et al. Systemic thromboembolic adverse events in patients treated with intravitreal anti-VEGF drugs for neovascular age-related macular degeneration. Expert Opin Biol Ther. 2012;12(10):1299-313.
    • (2012) Expert Opin Biol Ther. , vol.12 , Issue.10 , pp. 1299-1313
    • Costagliola, C.1    Agnifili, L.2    Arcidiacono, B.3    Duse, S.4    Fasanella, V.5    Mastropasqua, R.6
  • 48
    • 79955767772 scopus 로고    scopus 로고
    • Hypertension as a biomarker of efficacy in patients with metastatic renal cell carcinoma treated with sunitinib
    • 3086879 21527770 10.1093/jnci/djr128
    • Rini BI, Cohen DP, Lu DR, Chen I, Hariharan S, Gore ME, et al. Hypertension as a biomarker of efficacy in patients with metastatic renal cell carcinoma treated with sunitinib. J Natl Cancer Inst. 2011;103(9):763-73.
    • (2011) J Natl Cancer Inst. , vol.103 , Issue.9 , pp. 763-773
    • Rini, B.I.1    Cohen, D.P.2    Lu, D.R.3    Chen, I.4    Hariharan, S.5    Gore, M.E.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.