-
1
-
-
0029947186
-
Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
-
Druker BJ, Tamura S, Buchdunger E, et al: Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med 2:561-566, 1996
-
(1996)
Nat Med
, vol.2
, pp. 561-566
-
-
Druker, B.J.1
Tamura, S.2
Buchdunger, E.3
-
2
-
-
0035810147
-
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia
-
Druker BJ, Talpaz M, Resta DJ, et al: Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 344:1031-1037, 2001
-
(2001)
N Engl J Med
, vol.344
, pp. 1031-1037
-
-
Druker, B.J.1
Talpaz, M.2
Resta, D.J.3
-
3
-
-
0035810148
-
Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor
-
Joensuu H, Roberts PJ, Sarlomo-Rikala M, et al: Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor. N Engl J Med 344:1052-1056, 2001
-
(2001)
N Engl J Med
, vol.344
, pp. 1052-1056
-
-
Joensuu, H.1
Roberts, P.J.2
Sarlomo-Rikala, M.3
-
4
-
-
20844433223
-
Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: Randomised trial
-
Verweij J, Casali PG, Zalcberg J, et al: Progression-free survival in gastrointestinal stromal tumours with high-dose imatinib: Randomised trial. Lancet 364:1127-1134, 2004
-
(2004)
Lancet
, vol.364
, pp. 1127-1134
-
-
Verweij, J.1
Casali, P.G.2
Zalcberg, J.3
-
5
-
-
0642368571
-
Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor
-
Heinrich MC, Corless CL, Demetri GD, et al: Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor. J Clin Oncol 21:4342-4349, 2003
-
(2003)
J Clin Oncol
, vol.21
, pp. 4342-4349
-
-
Heinrich, M.C.1
Corless, C.L.2
Demetri, G.D.3
-
6
-
-
1642494654
-
Absolute bioavailability of imatinib (Glivec) orally versus intravenous infusion
-
Peng B, Dutreix C, Mehring G, et al: Absolute bioavailability of imatinib (Glivec) orally versus intravenous infusion. J Clin Pharmacol 44:158-162, 2004
-
(2004)
J Clin Pharmacol
, vol.44
, pp. 158-162
-
-
Peng, B.1
Dutreix, C.2
Mehring, G.3
-
7
-
-
1542608328
-
Pharmacokinetics and pharmacodynamics of imatinib in a phase I trial with chronic myeloid leukemia patients
-
Peng B, Hayes M, Resta D, et al: Pharmacokinetics and pharmacodynamics of imatinib in a phase I trial with chronic myeloid leukemia patients. J Clin Oncol 22:935-942, 2004
-
(2004)
J Clin Oncol
, vol.22
, pp. 935-942
-
-
Peng, B.1
Hayes, M.2
Resta, D.3
-
8
-
-
20144364602
-
Imatinib pharmacokinetics in patients with gastrointestinal stromal tumour: A retrospective population pharmacokinetic study over time - EORTC Soft Tissue and Bone Sarcoma Group
-
Judson I, Ma P, Peng B, et al: Imatinib pharmacokinetics in patients with gastrointestinal stromal tumour: A retrospective population pharmacokinetic study over time - EORTC Soft Tissue and Bone Sarcoma Group. Cancer Chemother Pharmacol 55:379-386, 2005
-
(2005)
Cancer Chemother Pharmacol
, vol.55
, pp. 379-386
-
-
Judson, I.1
Ma, P.2
Peng, B.3
-
9
-
-
0442313672
-
Effect of rifampicin on the pharmacokinetics of imatinib mesylate (Gleevec, STI571) in healthy subjects
-
Bolton AE, Peng B, Hubert M, et al: Effect of rifampicin on the pharmacokinetics of imatinib mesylate (Gleevec, STI571) in healthy subjects. Cancer Chemother Pharmacol 53:102-106, 2004
-
(2004)
Cancer Chemother Pharmacol
, vol.53
, pp. 102-106
-
-
Bolton, A.E.1
Peng, B.2
Hubert, M.3
-
10
-
-
0026743053
-
Clinical pharmacokinetics of epirubicin: The importance of liver biochemistry tests
-
Twelves CJ, Dobbs NA, Michael Y, et al: Clinical pharmacokinetics of epirubicin: The importance of liver biochemistry tests. Br J Cancer 66:765-769, 1992
-
(1992)
Br J Cancer
, vol.66
, pp. 765-769
-
-
Twelves, C.J.1
Dobbs, N.A.2
Michael, Y.3
-
11
-
-
0031982748
-
Population pharmacokinetics/ pharmacodynamics of docetaxel in phase II studies in patients with cancer
-
Bruno R, Hille D, Riva A, et al: Population pharmacokinetics/ pharmacodynamics of docetaxel in phase II studies in patients with cancer. J Clin Oncol 16:187-196, 1998
-
(1998)
J Clin Oncol
, vol.16
, pp. 187-196
-
-
Bruno, R.1
Hille, D.2
Riva, A.3
-
12
-
-
0030030354
-
Predicting etoposide toxicity: Relationship to organ function and protein binding
-
Joel SP, Shah R, Clark PI, et al: Predicting etoposide toxicity: Relationship to organ function and protein binding. J Clin Oncol 14:257-267, 1996
-
(1996)
J Clin Oncol
, vol.14
, pp. 257-267
-
-
Joel, S.P.1
Shah, R.2
Clark, P.I.3
-
13
-
-
0024440650
-
Carboplatin dosage: Prospective evaluation of a simple formula based on renal function
-
Calvert AH, Newell DR, Gumbrell LA, et al: Carboplatin dosage: Prospective evaluation of a simple formula based on renal function. J Clin Oncol 7:1748-1756, 1989
-
(1989)
J Clin Oncol
, vol.7
, pp. 1748-1756
-
-
Calvert, A.H.1
Newell, D.R.2
Gumbrell, L.A.3
-
14
-
-
0142121411
-
Imatinib mesylate (STI-571 Glivec, Gleevec) is an active agent for gastrointestinal stromal tumours, but does not yield responses in other soft-tissue sarcomas that are unselected for a molecular target: Results from an EORTC Soft Tissue and Bone Sarcoma Group phase II study
-
Verweij J, van Oosterom A, Blay JY, et al: Imatinib mesylate (STI-571 Glivec, Gleevec) is an active agent for gastrointestinal stromal tumours, but does not yield responses in other soft-tissue sarcomas that are unselected for a molecular target: Results from an EORTC Soft Tissue and Bone Sarcoma Group phase II study. Eur J Cancer 39:2006-2011, 2003
-
(2003)
Eur J Cancer
, vol.39
, pp. 2006-2011
-
-
Verweij, J.1
van Oosterom, A.2
Blay, J.Y.3
-
15
-
-
23644452642
-
Outcome of patients with advanced gastro-intestinal stromal tumours crossing over to a daily imatinib dose of 800 mg after progression on 400 mg
-
Zalcberg JR, Verweij J, Casali PG, et al: Outcome of patients with advanced gastro-intestinal stromal tumours crossing over to a daily imatinib dose of 800 mg after progression on 400 mg. Eur J Cancer 41:1751-1757, 2005
-
(2005)
Eur J Cancer
, vol.41
, pp. 1751-1757
-
-
Zalcberg, J.R.1
Verweij, J.2
Casali, P.G.3
-
16
-
-
33746401591
-
KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours
-
Debiec-Rychter M, Sciot R, Le Cesne A, et al: KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours. Eur J Cancer 42:1093-1103, 2006
-
(2006)
Eur J Cancer
, vol.42
, pp. 1093-1103
-
-
Debiec-Rychter, M.1
Sciot, R.2
Le Cesne, A.3
-
17
-
-
39149099201
-
Phase I and pharmacokinetic study of imatinib mesylate in patients with advanced malignancies and varying degrees of renal dysfunction: A study by the National Cancer Institute Organ Dysfunction Working Group
-
Gibbons J, Egorin ML, Ramanathan RK, et al: Phase I and pharmacokinetic study of imatinib mesylate in patients with advanced malignancies and varying degrees of renal dysfunction: A study by the National Cancer Institute Organ Dysfunction Working Group. J Clin Oncol 26:570-576, 2008
-
(2008)
J Clin Oncol
, vol.26
, pp. 570-576
-
-
Gibbons, J.1
Egorin, M.L.2
Ramanathan, R.K.3
-
18
-
-
39149100687
-
Phase I and pharmacokinetic study of imatinib mesylate in patients with advanced malignancies and varying degrees of liver dysfunction: A study by the National Cancer Institute Organ Dysfunction Working Group
-
Ramanathan RK, Egorin MJ, Takimoto CHM, et al: Phase I and pharmacokinetic study of imatinib mesylate in patients with advanced malignancies and varying degrees of liver dysfunction: A study by the National Cancer Institute Organ Dysfunction Working Group. J Clin Oncol 26:563-569, 2008
-
(2008)
J Clin Oncol
, vol.26
, pp. 563-569
-
-
Ramanathan, R.K.1
Egorin, M.J.2
Takimoto, C.H.M.3
-
19
-
-
0035146107
-
Downregulation of hepatic cytochrome P450 in chronic renal failure
-
Leblond F, Guevin C, Demers C, et al: Downregulation of hepatic cytochrome P450 in chronic renal failure. J Am Soc Nephrol 12:326-332, 2001
-
(2001)
J Am Soc Nephrol
, vol.12
, pp. 326-332
-
-
Leblond, F.1
Guevin, C.2
Demers, C.3
-
20
-
-
0025757336
-
The effect of renal failure on hepatic drug clearance
-
Touchette MA, Slaughter RL: The effect of renal failure on hepatic drug clearance. Dicp 25:1214-1224, 1991
-
(1991)
Dicp
, vol.25
, pp. 1214-1224
-
-
Touchette, M.A.1
Slaughter, R.L.2
-
21
-
-
0037539996
-
Characterization of hepatic cytochrome p4503A activity in patients with end-stage renal disease
-
Dowling TC, Briglia AE, Fink JC, et al: Characterization of hepatic cytochrome p4503A activity in patients with end-stage renal disease. Clin Pharmacol Ther 73:427-434, 2003
-
(2003)
Clin Pharmacol Ther
, vol.73
, pp. 427-434
-
-
Dowling, T.C.1
Briglia, A.E.2
Fink, J.C.3
-
22
-
-
0042305479
-
Alpha1 acid glycoprotein binds to imatinib (STI571) and substantially alters its pharmacokinetics in chronic myeloid leukemia patients
-
Gambacorti-Passerini C, Zucchetti M, Russo D, et al: Alpha1 acid glycoprotein binds to imatinib (STI571) and substantially alters its pharmacokinetics in chronic myeloid leukemia patients. Clin Cancer Res 9:625-632, 2003
-
(2003)
Clin Cancer Res
, vol.9
, pp. 625-632
-
-
Gambacorti-Passerini, C.1
Zucchetti, M.2
Russo, D.3
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