Chromosome-associated protein D3 promotes bacterial clearance in human intestinal epithelial cells by repressing expression of amino acid transporters

Gastroenterology

Volumn 148, Issue 7, 2015, Pages 1405-1416.e3

  Schuster, Andrew T ^a   Homer, Craig R ^a   Kemp, Jacqueline R ^a   Nickerson, Kourtney P ^a   Deutschman, Emily ^a   Kim, Yeojung ^a   West, Gail ^a   Sadler, Tammy ^a   Stylianou, Eleni ^a   Krokowski, Dawid ^b   Hatzoglou, Maria ^b   De La Motte, Carol ^a   Rubin, Brian P ^a,c   Fiocchi, Claudio ^a   McDonald, Christine ^a   Longworth, Michelle S ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c TAUSSIG CANCER INSTITUTE   (United States)

Author keywords

Condensin; Dysbiosis; Inflammatory Bowel Disease; Innate Immunity

Indexed keywords

AMINO ACID TRANSPORTER; CHROMOSOME ASSOCIATED PROTEIN D3; DNA NUCLEOTIDYLEXOTRANSFERASE; EARLY GROWTH RESPONSE FACTOR 1; EARLY GROWTH RESPONSE FACTOR 3; GENTAMICIN; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MEMBRANE PROTEIN; PROTEIN; SHORT HAIRPIN RNA; SLC7A5 PROTEIN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR FOSB; TRANSCRIPTION FACTOR JUNB; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATASE; CAP-D3 PROTEIN, DROSOPHILA; CD98 ANTIGEN; CELL CYCLE PROTEIN; CHROMOSOME-ASSOCIATED PROTEIN D3, HUMAN; DROSOPHILA PROTEIN; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; SLC3A2 PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BACTERIAL CELL; BACTERIAL CLEARANCE; BACTERIAL LOAD; BACTERIAL SURVIVAL; CACO 2 CELL LINE; CELL VACUOLE; COLON MUCOSA; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOPLASM; DISEASE ACTIVITY; EARLY RESPONSE GENE; ENDOSOME; ESCHERICHIA COLI; GENE EXPRESSION; GENE ONTOLOGY; GENE REPRESSION; HOST CELL; HT 29 CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; INTESTINE EPITHELIUM CELL; PATHOGENESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; SALMONELLOSIS; TISSUE SECTION; TUNEL ASSAY; ULCERATIVE COLITIS; UPREGULATION; CROHN DISEASE; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; INTESTINE MUCOSA; METABOLISM; MICROBIAL VIABILITY; MICROBIOLOGY; PHYSIOLOGY; RNA INTERFERENCE; SALMONELLA; SIGNAL TRANSDUCTION; TIME;

ADENOSINE TRIPHOSPHATASES; ANTIGENS, CD98 HEAVY CHAIN; AUTOPHAGY; CACO-2 CELLS; CELL CYCLE PROTEINS; COLITIS, ULCERATIVE; CROHN DISEASE; DROSOPHILA PROTEINS; EPITHELIAL CELLS; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; HT29 CELLS; HUMANS; IMMUNITY, INNATE; INTESTINAL MUCOSA; LARGE NEUTRAL AMINO ACID-TRANSPORTER 1; MICROBIAL VIABILITY; MULTIPROTEIN COMPLEXES; RNA INTERFERENCE; SALMONELLA; SIGNAL TRANSDUCTION; TIME FACTORS; TOR SERINE-THREONINE KINASES; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 84930036736     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2015.02.013     Document Type: Article

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