Error minimization in lateral inhibition circuits

Science Signaling

Volumn 3, Issue 129, 2010, Pages

  Barad, Omer ^a   Rosin, Dalia ^a   Hornstein, Eran ^a   Barkai, Naama ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

LIGAND; NOTCH RECEPTOR;

ARTICLE; DEVELOPMENTAL BIOLOGY; DROSOPHILA; ERROR; FLY; GENE MUTATION; MATHEMATICAL MODEL; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROBABILITY; SENSE ORGAN; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

ALGORITHMS; ANIMALS; CALCIUM-BINDING PROTEINS; CELL DIFFERENTIATION; COMPUTER SIMULATION; DROSOPHILA MELANOGASTER; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MODELS, NEUROLOGICAL; NEURAL INHIBITION; RECEPTORS, NOTCH; SENSE ORGANS; SENSORY RECEPTOR CELLS; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

EID: 77956634030     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2000857     Document Type: Article

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34. Acknowledgments: We thank J. W. Posakony, H. J. Bellen, F. B. Gao, E. C. Lai, F. Schweisguth, D. Van Meyel, M. Milan, B. Z. Shilo, and the Bloomington Stock Center for fly stocks and B. Nadler, B. Z. Shilo, and all our laboratory members for helpful discussions. Funding: O.B. is supported by the Azrieli Foundation and the Kahn Family Research Center for Systems Biology of the Human Cell. E.H. is the incumbent of the Helen and Milton A. Kimmelman Career Development Chair. This work was supported by the Israel Science Founction (E.H. and N.B.), the European Research Council (IDEA), Minerva, and the Hellen and Martin Kimmel award for innovative investigations (N.B.). Author contributions: O.B., E.H., and N.B. conceived the research. O.B. performed all the computational analysis and experiments. D.R. assisted with the experiments. O.B., E.H., and N.B. wrote the paper. Competing interests: The authors declare no competing interests.