Lycorine-derived phenanthridine downregulators of host Hsc70 as potential hepatitis C virus inhibitors

Future Medicinal Chemistry

Volumn 7, Issue 5, 2015, Pages 561-570

  Chen, Duozhi ^a   Cai, Jieyun ^a   Yin, Junlin ^a   Jiang, Jiandong ^b   Jing, Chenxu ^a,c   Zhu, Yanping ^b   Cheng, Junjun ^d   Di, Yingtong ^a   Zhang, Yu ^a   Cao, Mingming ^a   Li, Shunlin ^a   Peng, Zonggen ^b   Hao, Xiaojiang ^a  

^a KUNMING INSTITUTE OF BOTANY   (China)

^b INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

^c YUNNAN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^d INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; HEAT SHOCK COGNATE PROTEIN 70; LYCORINE; PHENANTHRIDINE DERIVATIVE; TELAPREVIR; AMARYLLIDACEAE ALKALOID;

ANTIVIRAL ACTIVITY; ARTICLE; CHEMICAL BOND; CONTROLLED STUDY; DOWN REGULATION; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; EC50; HEPATITIS C; HEPATITIS C VIRUS; HOST CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION; VIRUS INHIBITION; VIRUS REPLICATION; CELL LINE; CHEMISTRY; DRUG EFFECTS; GENETICS; HEPACIVIRUS; LIVER CELL; METABOLISM; PHYSIOLOGY; VIROLOGY;

AMARYLLIDACEAE ALKALOIDS; ANTIVIRAL AGENTS; CELL LINE; DOWN-REGULATION; HEPACIVIRUS; HEPATITIS C; HEPATOCYTES; HSC70 HEAT-SHOCK PROTEINS; HUMANS; PHENANTHRIDINES; VIRUS REPLICATION;

EID: 84929996767     PISSN: 17568919     EISSN: 17568927     Source Type: Journal    
DOI: 10.4155/fmc.15.14     Document Type: Article

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