-
1
-
-
84892805731
-
Cancer statistics, 2014
-
Siegel R, Ma J, Zou Z, Jemal A. Cancer statistics, 2014. CA Cancer J Clin 2014;64:9-29.
-
(2014)
CA Cancer J Clin
, vol.64
, pp. 9-29
-
-
Siegel, R.1
Ma, J.2
Zou, Z.3
Jemal, A.4
-
3
-
-
33646371709
-
Multiple genetic and epigenetic interacting mechanisms contribute to clonally selection of drugresistant tumors: Current views and new therapeutic prospective
-
Roberti A, La Sala D, Cinti C. Multiple genetic and epigenetic interacting mechanisms contribute to clonally selection of drugresistant tumors: current views and new therapeutic prospective. J Cell Physiol 2006;207:571-581.
-
(2006)
J Cell Physiol
, vol.207
, pp. 571-581
-
-
Roberti, A.1
La Sala, D.2
Cinti, C.3
-
4
-
-
33750603100
-
Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: Analysis of the surveillance, epidemiologic, and end results database
-
Govindan R, Page N, Morgensztern D, Read W, Tierney R, et al. Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: analysis of the surveillance, epidemiologic, and end results database. J Clin Oncol 2006;24: 4539-4544.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4539-4544
-
-
Govindan, R.1
Page, N.2
Morgensztern, D.3
Read, W.4
Tierney, R.5
-
5
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004;116:281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
6
-
-
72949093641
-
MicroRNAs as potential cancer therapeutics
-
Trang P, Weidhaas JB, Slack FJ. MicroRNAs as potential cancer therapeutics. Oncogene 2008;27(Suppl 2):S52-S57.
-
(2008)
Oncogene
, vol.27
, pp. S52-S57
-
-
Trang, P.1
Weidhaas, J.B.2
Slack, F.J.3
-
7
-
-
66449136951
-
Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
-
Kota J, Chivukula RR, O'Donnell KA, Wentzel EA, Montgomery CL, et al. Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 2009;137:1005-1017.
-
(2009)
Cell
, vol.137
, pp. 1005-1017
-
-
Kota, J.1
Chivukula, R.R.2
O'donnell, K.A.3
Wentzel, E.A.4
Montgomery, C.L.5
-
8
-
-
84907287148
-
Upregulation of Limk1 caused bymicroRNA-138 loss aggravates themetastasis of ovarian cancer by activation of Limk1/cofilin signaling
-
Chen P, Zeng M, Zhao Y, Fang X. Upregulation of Limk1 caused bymicroRNA-138 loss aggravates themetastasis of ovarian cancer by activation of Limk1/cofilin signaling. Oncol Rep. 2014
-
(2014)
Oncol Rep.
-
-
Chen, P.1
Zeng, M.2
Zhao, Y.3
Fang, X.4
-
9
-
-
84896695707
-
MiR-138 andMiR-135 directly target focal adhesion kinase, inhibit cell invasion, and increase sensitivity to chemotherapy in cancer cells
-
Golubovskaya VM, Sumbler B, Ho B, Yemma M, CanceWG.MiR-138 andMiR-135 directly target focal adhesion kinase, inhibit cell invasion, and increase sensitivity to chemotherapy in cancer cells. Anticancer Agents Med Chem 2014;14:18-28.
-
(2014)
Anticancer Agents Med Chem
, vol.14
, pp. 18-28
-
-
Golubovskaya, V.M.1
Sumbler, B.2
Ho, B.3
Yemma, M.4
Cance, W.G.5
-
10
-
-
84904527473
-
Prognostic potential of microRNA-138 and its target mRNA PDK1 in sera for patients with non-small cell lung cancer
-
Han L, Zhang G, Zhang N, Li H, Liu Y, et al. Prognostic potential of microRNA-138 and its target mRNA PDK1 in sera for patients with non-small cell lung cancer. Med Oncol 2014;31:129.
-
(2014)
Med Oncol
, vol.31
, pp. 129
-
-
Han, L.1
Zhang, G.2
Zhang, N.3
Li, H.4
Liu, Y.5
-
11
-
-
66149157349
-
MiR-24-mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells
-
Lal A, Pan Y, Navarro F, Dykxhoorn DM, Moreau L, et al. miR-24-mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells. Nat Struct Mol Biol 2009;16:492-498.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 492-498
-
-
Lal, A.1
Pan, Y.2
Navarro, F.3
Dykxhoorn, D.M.4
Moreau, L.5
-
12
-
-
76549127430
-
ATM is downregulated by N-Myc-regulated microRNA-421
-
Hu H, Du L, Nagabayashi G, Seeger RC, Gatti RA. ATM is downregulated by N-Myc-regulated microRNA-421. ProcNatl Acad Sci U S A 2010;107:1506-1511.
-
(2010)
ProcNatl Acad Sci U S A
, vol.107
, pp. 1506-1511
-
-
Hu, H.1
Du, L.2
Nagabayashi, G.3
Seeger, R.C.4
Gatti, R.A.5
-
13
-
-
77956896318
-
OncogenicWip1 phosphatase is inhibited by miR-16 in the DNA damage signaling pathway
-
Zhang X, Wan G, Mlotshwa S, Vance V, Berger FG, et al. OncogenicWip1 phosphatase is inhibited by miR-16 in the DNA damage signaling pathway. Cancer Res 2010;70:7176-7186.
-
(2010)
Cancer Res
, vol.70
, pp. 7176-7186
-
-
Zhang, X.1
Wan, G.2
Mlotshwa, S.3
Vance, V.4
Berger, F.G.5
-
14
-
-
67651149479
-
MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response
-
Pothof J, Verkaik NS, van IW, Wiemer EA, Ta VT, et al. MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response. EMBO J 2009;28:2090-2099.
-
(2009)
EMBO J
, vol.28
, pp. 2090-2099
-
-
Pothof, J.1
Verkaik, N.S.2
Van Iw Wiemer, E.A.3
Ta, V.T.4
-
15
-
-
84904961252
-
Up-regulation of microRNA-138 induce radiosensitization in lung cancer cells
-
Yang H, Tang Y, Guo W, Du Y, Wang Y, et al. Up-regulation of microRNA-138 induce radiosensitization in lung cancer cells. Tumour Biol 2014;35:6557-6565.
-
(2014)
Tumour Biol
, vol.35
, pp. 6557-6565
-
-
Yang, H.1
Tang, Y.2
Guo, W.3
Du, Y.4
Wang, Y.5
-
16
-
-
80051975920
-
MicroRNA-138 modulates DNA damage response by repressing histone H2AX expression
-
Wang Y, Huang JW, Li M, Cavenee WK, Mitchell PS, et al. MicroRNA-138 modulates DNA damage response by repressing histone H2AX expression. Mol Cancer Res 2011;9: 1100-1111.
-
(2011)
Mol Cancer Res
, vol.9
, pp. 1100-1111
-
-
Wang, Y.1
Huang, J.W.2
Li, M.3
Cavenee, W.K.4
Mitchell, P.S.5
-
17
-
-
0027928745
-
CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells
-
Cozens AL, Yezzi MJ, Kunzelmann K, Ohrui T, Chin L, et al. CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells. Am J Respir Cell Mol Biol 1994;10:38-47.
-
(1994)
Am J Respir Cell Mol Biol
, vol.10
, pp. 38-47
-
-
Cozens, A.L.1
Yezzi, M.J.2
Kunzelmann, K.3
Ohrui, T.4
Chin, L.5
-
18
-
-
84872797429
-
MicroRNA-221 induces cell survival and cisplatin resistance through PI3K/Akt pathway in human osteosarcoma
-
Zhao G, Cai C, Yang T, Qiu X, Liao B, et al. MicroRNA-221 induces cell survival and cisplatin resistance through PI3K/Akt pathway in human osteosarcoma. PLoS One 2013;8:e53906.
-
(2013)
PLoS One
, vol.8
, pp. e53906
-
-
Zhao, G.1
Cai, C.2
Yang, T.3
Qiu, X.4
Liao, B.5
-
19
-
-
0038820065
-
Phosphorylation of histone H2AX and activation ofMre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase i cleavage complexes
-
Furuta T, Takemura H, Liao ZY, Aune GJ, Redon C, et al. Phosphorylation of histone H2AX and activation ofMre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes. J Biol Chem 2003;278:20303-20312.
-
(2003)
J Biol Chem
, vol.278
, pp. 20303-20312
-
-
Furuta, T.1
Takemura, H.2
Liao, Z.Y.3
Aune, G.J.4
Redon, C.5
-
20
-
-
84903994994
-
PARP inhibitor activates the intrinsic pathway of apoptosis in primary lung cancer cells
-
Gangopadhyay NN, Luketich JD, Opest A, Landreneau R, Schuchert MJ. PARP inhibitor activates the intrinsic pathway of apoptosis in primary lung cancer cells. Cancer Invest 2014;32:339-348.
-
(2014)
Cancer Invest
, vol.32
, pp. 339-348
-
-
Gangopadhyay, N.N.1
Luketich, J.D.2
Opest, A.3
Landreneau, R.4
Schuchert, M.J.5
-
21
-
-
84902132551
-
Biological effects of (125)i seeds radiation on A549 lung cancer cells: G2/M arrest and enhanced cell death
-
Qu A, Wang H, Li J, Wang J, Liu J, et al. Biological effects of (125)i seeds radiation on A549 lung cancer cells: G2/M arrest and enhanced cell death. Cancer Invest 2014;32:209-217.
-
(2014)
Cancer Invest
, vol.32
, pp. 209-217
-
-
Qu, A.1
Wang, H.2
Li, J.3
Wang, J.4
Liu, J.5
-
22
-
-
0034707047
-
The DNA damage response: Putting checkpoints in perspective
-
Zhou BB, Elledge SJ. The DNA damage response: putting checkpoints in perspective. Nature 2000;408:433-439.
-
(2000)
Nature
, vol.408
, pp. 433-439
-
-
Zhou, B.B.1
Elledge, S.J.2
-
23
-
-
70450224676
-
H2AX: Functional roles and potential applications
-
Dickey JS, Redon CE, Nakamura AJ, Baird BJ, Sedelnikova OA, et al. H2AX: functional roles and potential applications. Chromosoma 2009;118:683-692.
-
(2009)
Chromosoma
, vol.118
, pp. 683-692
-
-
Dickey, J.S.1
Redon, C.E.2
Nakamura, A.J.3
Baird, B.J.4
Sedelnikova, O.A.5
-
24
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 1998;273:5858-5868.
-
(1998)
J Biol Chem
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
25
-
-
29244434544
-
MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks
-
Stucki M, Clapperton JA, Mohammad D, Yaffe MB, Smerdon SJ, et al. MDC1 directly binds phosphorylated histone H2AX to regulate cellular responses to DNA double-strand breaks. Cell 2005;123:1213-1226.
-
(2005)
Cell
, vol.123
, pp. 1213-1226
-
-
Stucki, M.1
Clapperton, J.A.2
Mohammad, D.3
Yaffe, M.B.4
Smerdon, S.J.5
-
26
-
-
3342915628
-
Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention
-
Lukas C, Melander F, Stucki M, Falck J, Bekker-Jensen S, et al. Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention. EMBO J 2004;23:2674-2683.
-
(2004)
EMBO J
, vol.23
, pp. 2674-2683
-
-
Lukas, C.1
Melander, F.2
Stucki, M.3
Falck, J.4
Bekker-Jensen, S.5
-
27
-
-
30744465308
-
MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals
-
Lou Z, Minter-Dykhouse K, Franco S, Gostissa M, Rivera MA, et al. MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals. Mol Cell 2006;21:187-200.
-
(2006)
Mol Cell
, vol.21
, pp. 187-200
-
-
Lou, Z.1
Minter-Dykhouse, K.2
Franco, S.3
Gostissa, M.4
Rivera, M.A.5
-
28
-
-
0037062492
-
Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX
-
Bassing CH, Chua KF, Sekiguchi J, Suh H, Whitlow SR, et al. Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX. Proc Natl Acad Sci U S A 2002;99:8173-8178.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 8173-8178
-
-
Bassing, C.H.1
Chua, K.F.2
Sekiguchi, J.3
Suh, H.4
Whitlow, S.R.5
-
29
-
-
0037012845
-
Genomic instability in mice lacking histone H2AX
-
Celeste A, Petersen S, Romanienko PJ, Fernandez-Capetillo O, Chen HT, et al. Genomic instability in mice lacking histone H2AX. Science 2002;296:922-927.
-
(2002)
Science
, vol.296
, pp. 922-927
-
-
Celeste, A.1
Petersen, S.2
Romanienko, P.J.3
Fernandez-Capetillo, O.4
Chen, H.T.5
-
30
-
-
84887222527
-
H2AX a promising biomarker for lung cancer: A review
-
Matthaios D, Hountis P, Karakitsos P, Bouros D, Kakolyris S. H2AX a promising biomarker for lung cancer: a review. Cancer Invest 2013;31:582-599.
-
(2013)
Cancer Invest
, vol.31
, pp. 582-599
-
-
Matthaios, D.1
Hountis, P.2
Karakitsos, P.3
Bouros, D.4
Kakolyris, S.5
-
31
-
-
84923264333
-
MiR-138 inhibits proliferation by targeting 3-phosphoinositide-dependent protein kinase-1 in non-small cell lung cancer cells
-
doi: 10.1111/crj.12100
-
Ye XW, Yu H, Jin YK, Jing XT, Xu M, et al. miR-138 inhibits proliferation by targeting 3-phosphoinositide-dependent protein kinase-1 in non-small cell lung cancer cells. Clin Respir J 2014;doi: 10.1111/crj.12100.
-
Clin Respir J 2014
-
-
Ye, X.W.1
Yu, H.2
Jin, Y.K.3
Jing, X.T.4
Xu, M.5
-
32
-
-
84887098976
-
Down-regulation of miR-138 promotes colorectal cancer metastasis via directly targeting TWIST2
-
Long L, Huang G, Zhu H, Guo Y, Liu Y, et al. Down-regulation of miR-138 promotes colorectal cancer metastasis via directly targeting TWIST2. J Transl Med 2013;11:275.
-
(2013)
J Transl Med
, vol.11
, pp. 275
-
-
Long, L.1
Huang, G.2
Zhu, H.3
Guo, Y.4
Liu, Y.5
-
33
-
-
84891384103
-
AmiRNA signature associated with human metastatic medullary thyroid carcinoma
-
Santarpia L, Calin GA, Adam L, Ye L, Fusco A, et al.AmiRNA signature associated with human metastatic medullary thyroid carcinoma. Endocr Relat Cancer 2013;20:809-823.
-
(2013)
Endocr Relat Cancer
, vol.20
, pp. 809-823
-
-
Santarpia, L.1
Calin, G.A.2
Adam, L.3
Ye, L.4
Fusco, A.5
-
34
-
-
84887494006
-
MicroRNA profile to predict gemcitabine resistance in bladder carcinoma cell lines
-
Kozinn SI, Harty NJ, Delong JM, Deliyiannis C, Logvinenko T, et al. MicroRNA profile to predict gemcitabine resistance in bladder carcinoma cell lines. Genes Cancer 2013;4:61-69.
-
(2013)
Genes Cancer
, vol.4
, pp. 61-69
-
-
Kozinn, S.I.1
Harty, N.J.2
Delong, J.M.3
Deliyiannis, C.4
Logvinenko, T.5
-
35
-
-
84877920467
-
MiR-138 overexpression is more powerful than hTERT knockdown to potentiate apigenin for apoptosis in neuroblastoma in vitro and in vivo
-
Chakrabarti M, Banik NL, Ray SK. miR-138 overexpression is more powerful than hTERT knockdown to potentiate apigenin for apoptosis in neuroblastoma in vitro and in vivo. Exp Cell Res 2013;319:1575-1585.
-
(2013)
Exp Cell Res
, vol.319
, pp. 1575-1585
-
-
Chakrabarti, M.1
Banik, N.L.2
Ray, S.K.3
-
36
-
-
84893415469
-
Gamma-H2AX: A novel prognostic marker in a prognosis prediction model of patients with early operable non-small cell lung cancer
-
Chatzimichail E, Matthaios D, Bouros D, Karakitsos P, Romanidis K, et al. gamma-H2AX: a novel prognostic marker in a prognosis prediction model of patients with early operable non-small cell lung cancer. Int J Genomics 2014;2014:160236.
-
(2014)
Int J Genomics
, vol.2014
, pp. 160236
-
-
Chatzimichail, E.1
Matthaios, D.2
Bouros, D.3
Karakitsos, P.4
Romanidis, K.5
-
37
-
-
84876677002
-
Radiosensitivity in breast cancer assessed by the histone gamma-H2AX and 53BP1 foci
-
Djuzenova CS, Elsner I, Katzer A, Worschech E, Distel LV, et al. Radiosensitivity in breast cancer assessed by the histone gamma-H2AX and 53BP1 foci. Radiat Oncol 2013;8:98.
-
(2013)
Radiat Oncol
, vol.8
, pp. 98
-
-
Djuzenova, C.S.1
Elsner, I.2
Katzer, A.3
Worschech, E.4
Distel, L.V.5
-
38
-
-
84880698245
-
Sensitive immunodetection of radiotoxicity after iodine-131 therapy for thyroid cancer using gamma-H2AX foci of DNA damage in lymphocytes
-
Doai M, Watanabe N, Takahashi T, Taniguchi M, Tonami H, et al. Sensitive immunodetection of radiotoxicity after iodine-131 therapy for thyroid cancer using gamma-H2AX foci of DNA damage in lymphocytes. Ann Nucl Med 2013;27:233-238.
-
(2013)
Ann Nucl Med
, vol.27
, pp. 233-238
-
-
Doai, M.1
Watanabe, N.2
Takahashi, T.3
Taniguchi, M.4
Tonami, H.5
-
39
-
-
84876253353
-
Decay of gamma-H2AX foci correlates with potentially lethal damage repair in prostate cancer cells
-
van Oorschot B, Hovingh SE, Rodermond H, Guclu A, Losekoot N, et al. Decay of gamma-H2AX foci correlates with potentially lethal damage repair in prostate cancer cells. Oncol Rep 2013;29:2175-2180.
-
(2013)
Oncol Rep
, vol.29
, pp. 2175-2180
-
-
Van Oorschot, B.1
Hovingh, S.E.2
Rodermond, H.3
Guclu, A.4
Losekoot, N.5
-
40
-
-
84891818318
-
MiRBase: Annotating high confidence microRNAs using deep sequencing data
-
Kozomara A, Griffiths-Jones S. miRBase: annotating high confidence microRNAs using deep sequencing data. Nucleic Acids Res 2014;42:D68-D73.
-
(2014)
Nucleic Acids Res
, vol.42
, pp. D68-D73
-
-
Kozomara, A.1
Griffiths-Jones, S.2
-
41
-
-
84879505852
-
Implications of microRNAs in the pathogenesis of diabetes
-
Park SY, Jeong HJ, Yang WM, Lee W. Implications of microRNAs in the pathogenesis of diabetes. Arch PharmRes 2013;36:154-166.
-
(2013)
Arch PharmRes
, vol.36
, pp. 154-166
-
-
Park, S.Y.1
Jeong, H.J.2
Yang, W.M.3
Lee, W.4
-
43
-
-
84887075238
-
Endothelial microparticle-mediated transfer of MicroRNA-126 promotes vascular endothelial cell repair via SPRED1 and is abrogated in glucose-damaged endothelial microparticles
-
Jansen F, Yang X, Hoelscher M, Cattelan A, Schmitz T, et al. Endothelial microparticle-mediated transfer of MicroRNA-126 promotes vascular endothelial cell repair via SPRED1 and is abrogated in glucose-damaged endothelial microparticles. Circulation 2013;128:2026-2038.
-
(2013)
Circulation
, vol.128
, pp. 2026-2038
-
-
Jansen, F.1
Yang, X.2
Hoelscher, M.3
Cattelan, A.4
Schmitz, T.5
-
44
-
-
84901371386
-
Role, function and therapeutic potential of microRNAs in vascular aging
-
Jansen F, Yang X, Nickenig G, Werner N, Vasa-Nicotera M. Role, function and therapeutic potential of microRNAs in vascular aging. Curr Vasc Pharmacol. 2013
-
(2013)
Curr Vasc Pharmacol.
-
-
Jansen, F.1
Yang, X.2
Nickenig, G.3
Werner, N.4
Vasa-Nicotera, M.5
-
45
-
-
84906266519
-
Progress and challenge ofmicroRNA research in immunity
-
Lee HM, Nguyen DT, Lu LF.Progress and challenge ofmicroRNA research in immunity. Front Genet 2014;5:178.
-
(2014)
Front Genet
, vol.5
, pp. 178
-
-
Lee, H.M.1
Nguyen, D.T.2
Lu, L.F.3
-
46
-
-
84872816163
-
MiR-138 inhibits tumor growth through repression of EZH2 in non-small cell lung cancer
-
Zhang H, Zhang H, Zhao M, Lv Z, Zhang X, et al.MiR-138 inhibits tumor growth through repression of EZH2 in non-small cell lung cancer. Cell Physiol Biochem 2013;31:56-65.
-
(2013)
Cell Physiol Biochem
, vol.31
, pp. 56-65
-
-
Zhang, H.1
Zhang, H.2
Zhao, M.3
Lv, Z.4
Zhang, X.5
|