Methylation of Gata3 protein at Arg-261 regulates transactivation of the Il5 gene in T helper 2 cells

Journal of Biological Chemistry

Volumn 290, Issue 21, 2015, Pages 13095-13103

  Hosokawa, Hiroyuki ^a   Kato, Miki ^a   Tohyama, Hiroyuki ^a   Tamaki, Yuuki ^a   Endo, Yusuke ^a   Kimura, Motoko Y ^a   Tumes, Damon John ^a   Motohashi, Shinichiro ^b   Matsumoto, Masaki ^a,c   Nakayama, Keiichi I ^a   Tanaka, Tomoaki ^a,d   Nakayama, Toshinori ^a,d  

^a CHIBA UNIVERSITY   (Japan)

^b Department of Medical Immunology ^*  (Japan)

^c KYUSHU UNIVERSITY   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATION; AMINO ACIDS; CELL PROLIFERATION; CYTOLOGY; GENES; METHYLATION; PROTEINS;

CELL DIFFERENTIATION; CHROMATIN REMODELING; HEAT SHOCK PROTEIN; MASTER REGULATORS; RNA POLYMERASE II; TARGET GENES; TRANSACTIVATION; TRANSCRIPTIONAL ACTIVATIONS;

CELLS;

ARGININE; ARGININE 261; CHAPERONIN 60; INTERLEUKIN 4; INTERLEUKIN 5; RNA POLYMERASE II; TRANSCRIPTION FACTOR GATA 3; UNCLASSIFIED DRUG; CYTOKINE; GATA3 PROTEIN, MOUSE; HSPD1 PROTEIN, MOUSE; MESSENGER RNA; MITOCHONDRIAL PROTEIN; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME REPRESSION; GENE EXPRESSION; GENE TARGETING; IL5 GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN METHYLATION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; TH1 CELL; TH2 CELL; TRANSACTIVATION; TRANSCRIPTION ELONGATION; AMINO ACID SEQUENCE; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL CULTURE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN IMMUNOPRECIPITATION; DNA METHYLATION; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; IMMUNOLOGY; IMMUNOPRECIPITATION; METABOLISM; MOLECULAR GENETICS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; TRANSCRIPTION INITIATION; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; ARGININE; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CHAPERONIN 60; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN IMMUNOPRECIPITATION; CYTOKINES; DNA METHYLATION; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GATA3 TRANSCRIPTION FACTOR; IMMUNOPRECIPITATION; INTERLEUKIN-5; MICE; MICE, INBRED C57BL; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SEQUENCE HOMOLOGY, AMINO ACID; TH1 CELLS; TH2 CELLS; TRANSCRIPTIONAL ACTIVATION;

EID: 84929995557     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.621524     Document Type: Article

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