Advanced glycation end-products induce apoptosis in pancreatic islet endothelial cells via NF-κB-activated cyclooxygenase-2/prostaglandin e2 up-regulation

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Lan, Kuo Cheng ^a   Chiu, Chen Yuan ^b   Kao, Chia Wei ^b   Huang, Kuo How ^c   Wang, Ching Chia ^c   Huang, Kuo Tong ^b   Tsai, Keh Sung ^c   Sheu, Meei Ling ^d   Liu, Shing Hwa ^b,c,e  

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^e CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCATION END PRODUCT RECEPTOR; CASPASE 3; CYCLOOXYGENASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROSTAGLANDIN E2; TRANSCRIPTION FACTOR RELA; PTGS2 PROTEIN, MOUSE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIOACCUMULATION; CELL MEDIATED CYTOTOXICITY; CELL VIABILITY; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME INHIBITION; IN VITRO STUDY; MOUSE; MS1 CELL LINE; NONHUMAN; PANCREAS ISLET CELL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; BIOSYNTHESIS; CELL LINE; CELL SURVIVAL; DIABETIC ANGIOPATHY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; METABOLISM; PANCREAS ISLET; PATHOLOGY; PHYSIOLOGY; VASCULARIZATION;

ANIMALS; APOPTOSIS; CELL LINE; CELL SURVIVAL; CYCLOOXYGENASE 2; DIABETIC ANGIOPATHIES; DINOPROSTONE; ENDOPLASMIC RETICULUM STRESS; ENDOTHELIAL CELLS; ENZYME ACTIVATION; GLYCOSYLATION END PRODUCTS, ADVANCED; ISLETS OF LANGERHANS; MICE; NF-KAPPA B; UP-REGULATION;

EID: 84929994666     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0124418     Document Type: Article

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