LR-90 prevents methylglyoxal-induced oxidative stress and apoptosis in human endothelial cells

Apoptosis

Volumn 19, Issue 5, 2014, Pages 776-788

  Figarola, James L ^a   Singhal, Jyotsana ^a   Rahbar, Samuel ^a   Awasthi, Sanjay ^a   Singhal, Sharad S ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Atherosclerosis; Diabetes; Glycation; Methylglyoxal; Oxidative stress

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; LR 90; METHYLGLYOXAL; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTECTIVE AGENT; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SECRETION; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL;

ANTIOXIDANTS; APOPTOSIS; BUTYRATES; CASPASES; CYTOCHROMES C; ENZYME ACTIVATION; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOCHONDRIAL MEMBRANES; MITOGEN-ACTIVATED PROTEIN KINASES; OXIDATIVE STRESS; PYRUVALDEHYDE; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84898906334     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-014-0974-3     Document Type: Article

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