메뉴 건너뛰기




Volumn 405, Issue 1-2, 2015, Pages 187-196

Baicalein suppresses the viability of MG-63 osteosarcoma cells through inhibiting c-MYC expression via Wnt signaling pathway

Author keywords

Baicalein; BANCR; c MYC; Osteosarcoma; Wnt; catenin

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BAICALEIN; BETA CATENIN; JANUS KINASE; MYC PROTEIN; WNT PROTEIN; FLAVANONE DERIVATIVE;

EID: 84929965087     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-015-2410-6     Document Type: Article
Times cited : (34)

References (34)
  • 1
    • 77953666914 scopus 로고    scopus 로고
    • Osteosarcoma multidisciplinary approach to the management from the pathologist’s perspective
    • PID: 20213386
    • Raymond AK, Jaffe N (2009) Osteosarcoma multidisciplinary approach to the management from the pathologist’s perspective. Cancer Treat Res 152:63–84. doi:10.1007/978-1-4419-0284-9_4
    • (2009) Cancer Treat Res , vol.152 , pp. 63-84
    • Raymond, A.K.1    Jaffe, N.2
  • 2
    • 50649107280 scopus 로고    scopus 로고
    • Therapy for osteosarcoma: where do we go from here?
    • PID: 18754698
    • Chou AJ, Geller DS, Gorlick R (2008) Therapy for osteosarcoma: where do we go from here? Paediatr Drugs 10:315–327
    • (2008) Paediatr Drugs , vol.10 , pp. 315-327
    • Chou, A.J.1    Geller, D.S.2    Gorlick, R.3
  • 3
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • COI: 1:CAS:528:DC%2BC3MXjsFeqtrk%3D, PID: 21376230
    • Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144:646–674. doi:10.1016/j.cell.2011.02.013
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 4
    • 84896690540 scopus 로고    scopus 로고
    • Osteosarcoma treatment—where do we stand? A state of the art review
    • PID: 24345772
    • Luetke A, Meyers PA, Lewis I, Juergens H (2014) Osteosarcoma treatment—where do we stand? A state of the art review. Cancer Treat Rev 40:523–532. doi:10.1016/j.ctrv.2013.11.006
    • (2014) Cancer Treat Rev , vol.40 , pp. 523-532
    • Luetke, A.1    Meyers, P.A.2    Lewis, I.3    Juergens, H.4
  • 5
    • 84862207240 scopus 로고    scopus 로고
    • Three decades of Wnts: a personal perspective on how a scientific field developed
    • COI: 1:CAS:528:DC%2BC38XntlSls7w%3D, PID: 22617420
    • Nusse R, Varmus H (2012) Three decades of Wnts: a personal perspective on how a scientific field developed. EMBO J 31:2670–2684. doi:10.1038/emboj.2012.146
    • (2012) EMBO J , vol.31 , pp. 2670-2684
    • Nusse, R.1    Varmus, H.2
  • 6
    • 1842535903 scopus 로고    scopus 로고
    • Shutting down Wnt signal-activated cancer
    • COI: 1:CAS:528:DC%2BD2cXis1aiu7Y%3D, PID: 15054482
    • Taketo MM (2004) Shutting down Wnt signal-activated cancer. Nat Genet 36:320–322. doi:10.1038/ng0404-320
    • (2004) Nat Genet , vol.36 , pp. 320-322
    • Taketo, M.M.1
  • 7
    • 67650230896 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling: components, mechanisms, and diseases
    • COI: 1:CAS:528:DC%2BD1MXpsV2msb8%3D, PID: 19619488
    • MacDonald BT, Tamai K, He X (2009) Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell 17:9–26. doi:10.1016/j.devcel.2009.06.016
    • (2009) Dev Cell , vol.17 , pp. 9-26
    • MacDonald, B.T.1    Tamai, K.2    He, X.3
  • 9
    • 1942502419 scopus 로고    scopus 로고
    • Efficient synthesis and structure-activity relationship of honokiol, a neurotrophic biphenyl-type neolignan
    • COI: 1:CAS:528:DC%2BD2cXjsVKhtbs%3D, PID: 15109665
    • Esumi T, Makado G, Zhai H, Shimizu Y, Mitsumoto Y, Fukuyama Y (2004) Efficient synthesis and structure-activity relationship of honokiol, a neurotrophic biphenyl-type neolignan. Bioorg Med Chem Lett 14:2621–2625. doi:10.1016/j.bmcl.2004.02.067
    • (2004) Bioorg Med Chem Lett , vol.14 , pp. 2621-2625
    • Esumi, T.1    Makado, G.2    Zhai, H.3    Shimizu, Y.4    Mitsumoto, Y.5    Fukuyama, Y.6
  • 10
    • 84875989510 scopus 로고    scopus 로고
    • Honokiol inhibits non-small cell lung cancer cell migration by targeting PGE(2)-mediated activation of beta-catenin signaling
    • COI: 1:CAS:528:DC%2BC3sXmtlSmsrg%3D, PID: 23580348
    • Singh T, Katiyar SK (2013) Honokiol inhibits non-small cell lung cancer cell migration by targeting PGE(2)-mediated activation of beta-catenin signaling. PLoS One 8:e60749. doi:10.1371/journal.pone.0060749
    • (2013) PLoS One , vol.8 , pp. e60749
    • Singh, T.1    Katiyar, S.K.2
  • 11
    • 84903437794 scopus 로고    scopus 로고
    • Long non-coding RNA BANCR promotes proliferation in malignant melanoma by regulating MAPK pathway activation
    • PID: 24967732
    • Li R, Zhang L, Jia L, Duan Y, Li Y, Bao L, Sha N (2014) Long non-coding RNA BANCR promotes proliferation in malignant melanoma by regulating MAPK pathway activation. PLoS One 9:e100893
    • (2014) PLoS One , vol.9 , pp. e100893
    • Li, R.1    Zhang, L.2    Jia, L.3    Duan, Y.4    Li, Y.5    Bao, L.6    Sha, N.7
  • 12
    • 0024162530 scopus 로고
    • Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice
    • COI: 1:CAS:528:DyaL1MXitV2q, PID: 3180222
    • Tsukamoto AS, Grosschedl R, Guzman RC, Parslow T, Varmus HE (1988) Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. Cell 55:619–625
    • (1988) Cell , vol.55 , pp. 619-625
    • Tsukamoto, A.S.1    Grosschedl, R.2    Guzman, R.C.3    Parslow, T.4    Varmus, H.E.5
  • 13
    • 84871846692 scopus 로고    scopus 로고
    • WNT signalling pathways as therapeutic targets in cancer
    • COI: 1:CAS:528:DC%2BC38XhvVKnsrjL, PID: 23258168
    • Anastas JN, Moon RT (2013) WNT signalling pathways as therapeutic targets in cancer. Nat Rev Cancer 13:11–26. doi:10.1038/nrc3419
    • (2013) Nat Rev Cancer , vol.13 , pp. 11-26
    • Anastas, J.N.1    Moon, R.T.2
  • 14
    • 84870161284 scopus 로고    scopus 로고
    • Honokiol: a novel natural agent for cancer prevention and therapy
    • COI: 1:CAS:528:DC%2BC3sXjvVSltw%3D%3D, PID: 22834827
    • Arora S, Singh S, Piazza GA, Contreras CM, Panyam J, Singh AP (2012) Honokiol: a novel natural agent for cancer prevention and therapy. Curr Mol Med 12:1244–1252
    • (2012) Curr Mol Med , vol.12 , pp. 1244-1252
    • Arora, S.1    Singh, S.2    Piazza, G.A.3    Contreras, C.M.4    Panyam, J.5    Singh, A.P.6
  • 15
    • 0037205315 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta: a novel regulator of cardiac hypertrophy and development
    • COI: 1:CAS:528:DC%2BD38XktlSnsLc%3D, PID: 12039794
    • Hardt SE, Sadoshima J (2002) Glycogen synthase kinase-3beta: a novel regulator of cardiac hypertrophy and development. Circ Res 90:1055–1063
    • (2002) Circ Res , vol.90 , pp. 1055-1063
    • Hardt, S.E.1    Sadoshima, J.2
  • 16
    • 33645411180 scopus 로고    scopus 로고
    • Wnt-1 signal as a potential cancer therapeutic target
    • COI: 1:CAS:528:DC%2BD28XjtlCktr8%3D, PID: 16550254
    • You L, Kim J, He B, Xu Z, McCormick F, Jablons DM (2006) Wnt-1 signal as a potential cancer therapeutic target. Drug News Perspect 19:27–31. doi:10.1358/dnp.2005.19.1.965871
    • (2006) Drug News Perspect , vol.19 , pp. 27-31
    • You, L.1    Kim, J.2    He, B.3    Xu, Z.4    McCormick, F.5    Jablons, D.M.6
  • 17
    • 0035825119 scopus 로고    scopus 로고
    • Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription
    • COI: 1:CAS:528:DC%2BD3MXjslyitw%3D%3D, PID: 11149923
    • Chen S, Guttridge DC, You Z, Zhang Z, Fribley A, Mayo MW, Kitajewski J, Wang CY (2001) Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription. J Cell Biol 152:87–96
    • (2001) J Cell Biol , vol.152 , pp. 87-96
    • Chen, S.1    Guttridge, D.C.2    You, Z.3    Zhang, Z.4    Fribley, A.5    Mayo, M.W.6    Kitajewski, J.7    Wang, C.Y.8
  • 18
    • 84876213674 scopus 로고    scopus 로고
    • Downregulation of Sp1 is involved in honokiol-induced cell cycle arrest and apoptosis in human malignant pleural mesothelioma cells
    • COI: 1:CAS:528:DC%2BC3sXpsFCkt7g%3D, PID: 23525508
    • Chae JI, Jeon YJ, Shim JH (2013) Downregulation of Sp1 is involved in honokiol-induced cell cycle arrest and apoptosis in human malignant pleural mesothelioma cells. Oncol Rep 29:2318–2324. doi:10.3892/or.2013.2353
    • (2013) Oncol Rep , vol.29 , pp. 2318-2324
    • Chae, J.I.1    Jeon, Y.J.2    Shim, J.H.3
  • 19
    • 84866524759 scopus 로고    scopus 로고
    • Honokiol exerts an anticancer effect in T98G human glioblastoma cells through the induction of apoptosis and the regulation of adhesion molecules
    • COI: 1:CAS:528:DC%2BC38XhsFyntLbP, PID: 22895699
    • Jeong JJ, Lee JH, Chang KC, Kim HJ (2012) Honokiol exerts an anticancer effect in T98G human glioblastoma cells through the induction of apoptosis and the regulation of adhesion molecules. Int J Oncol 41:1358–1364. doi:10.3892/ijo.2012.1582
    • (2012) Int J Oncol , vol.41 , pp. 1358-1364
    • Jeong, J.J.1    Lee, J.H.2    Chang, K.C.3    Kim, H.J.4
  • 20
    • 39749131007 scopus 로고    scopus 로고
    • Honokiol, a constituent of oriental medicinal herb magnolia officinalis, inhibits growth of PC-3 xenografts in vivo in association with apoptosis induction
    • COI: 1:CAS:528:DC%2BD1cXhvF2nt7w%3D, PID: 18281560
    • Hahm ER, Arlotti JA, Marynowski SW, Singh SV (2008) Honokiol, a constituent of oriental medicinal herb magnolia officinalis, inhibits growth of PC-3 xenografts in vivo in association with apoptosis induction. Clin Cancer Res 14:1248–1257. doi:10.1158/1078-0432.CCR-07-1926
    • (2008) Clin Cancer Res , vol.14 , pp. 1248-1257
    • Hahm, E.R.1    Arlotti, J.A.2    Marynowski, S.W.3    Singh, S.V.4
  • 21
    • 50149089033 scopus 로고    scopus 로고
    • Synergistic antitumor effects of liposomal honokiol combined with adriamycin in breast cancer models
    • COI: 1:CAS:528:DC%2BD1cXhtFWqu73M, PID: 18570244
    • Hou W, Chen L, Yang G, Zhou H, Jiang Q, Zhong Z, Hu J, Chen X, Wang X, Yuan Y, Tang M, Wen J, Wei Y (2008) Synergistic antitumor effects of liposomal honokiol combined with adriamycin in breast cancer models. Phytother Res 22:1125–1132. doi:10.1002/ptr.2472
    • (2008) Phytother Res , vol.22 , pp. 1125-1132
    • Hou, W.1    Chen, L.2    Yang, G.3    Zhou, H.4    Jiang, Q.5    Zhong, Z.6    Hu, J.7    Chen, X.8    Wang, X.9    Yuan, Y.10    Tang, M.11    Wen, J.12    Wei, Y.13
  • 22
    • 71649087878 scopus 로고    scopus 로고
    • Wnt signaling in mitosis
    • COI: 1:CAS:528:DC%2BC3cXht1CjsLY%3D, PID: 20059944
    • Kaldis P, Pagano M (2009) Wnt signaling in mitosis. Dev Cell 17:749–750. doi:10.1016/j.devcel.2009.12.001
    • (2009) Dev Cell , vol.17 , pp. 749-750
    • Kaldis, P.1    Pagano, M.2
  • 23
    • 3142590865 scopus 로고    scopus 로고
    • Wnt signaling and breast cancer
    • COI: 1:CAS:528:DC%2BD2cXjsVGiurs%3D, PID: 14739782
    • Howe LR, Brown AM (2004) Wnt signaling and breast cancer. Cancer Biol Ther 3:36–41
    • (2004) Cancer Biol Ther , vol.3 , pp. 36-41
    • Howe, L.R.1    Brown, A.M.2
  • 25
    • 79955479314 scopus 로고    scopus 로고
    • Wnt/β-Catenin activation promotes prostate tumor progression in a mouse model
    • PID: 21151173
    • Yu X, Wang Y, DeGraff DJ, Wills ML, Matusik RJ (2010) Wnt/β-Catenin activation promotes prostate tumor progression in a mouse model. Oncogene 30:1868–1879
    • (2010) Oncogene , vol.30 , pp. 1868-1879
    • Yu, X.1    Wang, Y.2    DeGraff, D.J.3    Wills, M.L.4    Matusik, R.J.5
  • 26
    • 79958244521 scopus 로고    scopus 로고
    • HEF1, a novel target of Wnt signaling, promotes colonic cell migration and cancer progression
    • COI: 1:CAS:528:DC%2BC3MXhvVGjs7w%3D, PID: 21317929
    • Li Y, Bavarva JH, Wang Z, Guo J, Qian C, Thibodeau SN, Golemis EA, Liu W (2011) HEF1, a novel target of Wnt signaling, promotes colonic cell migration and cancer progression. Oncogene 30:2633–2643
    • (2011) Oncogene , vol.30 , pp. 2633-2643
    • Li, Y.1    Bavarva, J.H.2    Wang, Z.3    Guo, J.4    Qian, C.5    Thibodeau, S.N.6    Golemis, E.A.7    Liu, W.8
  • 29
    • 84861881510 scopus 로고    scopus 로고
    • BRAFV600E remodels the melanocyte transcriptome and induces BANCR to regulate melanoma cell migration
    • COI: 1:CAS:528:DC%2BC38XoslSisLY%3D, PID: 22581800
    • Flockhart RJ, Webster DE, Qu K, Mascarenhas N, Kovalski J, Kretz M, Khavari PA (2012) BRAFV600E remodels the melanocyte transcriptome and induces BANCR to regulate melanoma cell migration. Genome Res 22:1006–1014
    • (2012) Genome Res , vol.22 , pp. 1006-1014
    • Flockhart, R.J.1    Webster, D.E.2    Qu, K.3    Mascarenhas, N.4    Kovalski, J.5    Kretz, M.6    Khavari, P.A.7
  • 30
    • 84899157532 scopus 로고    scopus 로고
    • Downregulation of BRAF activated non-coding RNA is associated with poor prognosis for non-small cell lung cancer and promotes metastasis by affecting epithelial–mesenchymal transition
    • PID: 24655544
    • Sun M, Liu X-H, Wang K-M, F-q Nie, Kong R, J-s Yang, Xia R, Xu T-P, Jin F-Y, Liu Z-J (2014) Downregulation of BRAF activated non-coding RNA is associated with poor prognosis for non-small cell lung cancer and promotes metastasis by affecting epithelial–mesenchymal transition. Mol Cancer 13:68
    • (2014) Mol Cancer , vol.13 , pp. 68
    • Sun, M.1    Liu, X.-H.2    Wang, K.-M.3    F-q, N.4    Kong, R.5    J-s, Y.6    Xia, R.7    Xu, T.-P.8    Jin, F.-Y.9    Liu, Z.-J.10
  • 31
    • 84922225667 scopus 로고    scopus 로고
    • Long non-coding RNA BANCR promotes proliferation and migration of lung carcinoma via MAPK pathways
    • COI: 1:CAS:528:DC%2BC2cXhvF2htbjE, PID: 25661343
    • Jiang W, Zhang D, Xu B, Wu Z, Liu S, Zhang L, Tian Y, Han X, Tian D (2015) Long non-coding RNA BANCR promotes proliferation and migration of lung carcinoma via MAPK pathways. Biomed Pharmacother 69:90–95
    • (2015) Biomed Pharmacother , vol.69 , pp. 90-95
    • Jiang, W.1    Zhang, D.2    Xu, B.3    Wu, Z.4    Liu, S.5    Zhang, L.6    Tian, Y.7    Han, X.8    Tian, D.9
  • 32
    • 16844387124 scopus 로고    scopus 로고
    • Role of JNK activation in apoptosis: a double-edged sword
    • Jing L, Anning L (2005) Role of JNK activation in apoptosis: a double-edged sword. Cell Res 15:36–42
    • (2005) Cell Res , vol.15 , pp. 36-42
    • Jing, L.1    Anning, L.2
  • 33
    • 79958027982 scopus 로고    scopus 로고
    • Baicalein alleviates diabetic peripheral neuropathy through inhibition of oxidative–nitrosative stress and p38 MAPK activation
    • COI: 1:CAS:528:DC%2BC3MXnsVWhs7c%3D, PID: 21515260
    • Stavniichuk R, Drel VR, Shevalye H, Maksimchyk Y, Kuchmerovska TM, Nadler JL, Obrosova IG (2011) Baicalein alleviates diabetic peripheral neuropathy through inhibition of oxidative–nitrosative stress and p38 MAPK activation. Exp Neurol 230:106–113
    • (2011) Exp Neurol , vol.230 , pp. 106-113
    • Stavniichuk, R.1    Drel, V.R.2    Shevalye, H.3    Maksimchyk, Y.4    Kuchmerovska, T.M.5    Nadler, J.L.6    Obrosova, I.G.7
  • 34
    • 74949106101 scopus 로고    scopus 로고
    • The combination of baicalin and baicalein enhances apoptosis via the ERK/p38 MAPK pathway in human breast cancer cells
    • Q-m Zhou, Wang S, Zhang H, Y-y Lu, X-f Wang, Motoo Y, S-b Su (2009) The combination of baicalin and baicalein enhances apoptosis via the ERK/p38 MAPK pathway in human breast cancer cells. Acta Pharmacol Sin 30:1648–1658
    • (2009) Acta Pharmacol Sin , vol.30 , pp. 1648-1658
    • Q-m, Z.1    Wang, S.2    Zhang, H.3    Y-y, L.4    X-f, W.5    Motoo, Y.6    S-b, S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.