A high-resolution genomic analysis of multidrug-resistant hospital outbreaks of Klebsiella pneumoniae

EMBO Molecular Medicine

Volumn 7, Issue 3, 2015, Pages 227-239

  Chung The, Hao ^a   Karkey, Abhilasha ^a   Pham Thanh, Duy ^a   Boinett, Christine J ^b   Cain, Amy K ^b   Ellington, Matthew ^b,c   Baker, Kate S ^b   Dongol, Sabina ^a   Thompson, Corinne ^a,d   Harris, Simon R ^b   Jombart, Thibaut ^e   Le Thi Phuong, Tu ^a   Tran Do Hoang, Nhu ^a   Ha Thanh, Tuyen ^a   Shretha, Shrijana ^a   Joshi, Suchita ^a   Basnyat, Buddha ^a   Thwaites, Guy ^a,d   Thomson, Nicholas R ^b,f   Rabaa, Maia A ^a,g   Baker, Stephen ^a,d,f   more..

^a OXFORD UNIVERSITY CLINICAL RESEARCH UNIT   (Viet Nam)

^b WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^c ADDENBROOKE S HOSPITAL   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

^f LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^g UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Antimicrobial resistance; Bloodstream infections; Carbapenemases; Klebsiella pneumoniae; Nosocomial infections

Indexed keywords

AMIKACIN; AMOXICILLIN; ANTIBIOTIC AGENT; BETA LACTAMASE; BETA LACTAMASE NDM 1; CARBAPENEM DERIVATIVE; CEFOTAXIME; CHLORAMPHENICOL; CIPROFLOXACIN; COTRIMOXAZOLE; GENTAMICIN; IMIPENEM; MEROPENEM; OFLOXACIN; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ADULT; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BLOODSTREAM INFECTION; CHILD; CONTROLLED STUDY; EPIDEMIC; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC LINE; GENETIC TRAIT; GENOMICS; HOSPITAL; HOSPITAL PERSONNEL; HUMAN; INFECTION CONTROL; KLEBSIELLA PNEUMONIAE; KLEBSIELLA PNEUMONIAE INFECTION; MAJOR CLINICAL STUDY; MULTIDRUG RESISTANCE; NEWBORN; PHYLOGENY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; WARD; WHOLE GENOME SEQUENCING; YOUNG ADULT; ANIMAL; BACTERIAL GENOME; CLASSIFICATION; CLUSTER ANALYSIS; CROSS INFECTION; DNA SEQUENCE; DRUG EFFECTS; GENETICS; GENOTYPE; ISOLATION AND PURIFICATION; KLEBSIELLA INFECTIONS; MICROBIOLOGY; MOLECULAR EVOLUTION; MOLECULAR GENETICS; MOUSE; NEPAL; PROCEDURES; SEQUENCE HOMOLOGY;

ANIMALS; CLUSTER ANALYSIS; CROSS INFECTION; DISEASE OUTBREAKS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; EVOLUTION, MOLECULAR; GENES, BACTERIAL; GENOME, BACTERIAL; GENOMICS; GENOTYPE; HUMANS; INFECTION CONTROL; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MICE; MOLECULAR SEQUENCE DATA; NEPAL; PHYLOGENY; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY; VIRULENCE FACTORS;

EID: 84929838068     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.15252/emmm.201404767     Document Type: Article

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