Emergence of NDM-1-producing Klebsiella pneumoniae in Morocco

Journal of Antimicrobial Chemotherapy

Volumn 66, Issue 12, 2011, Pages 2781-2783

  Poirel, Laurent ^a   Benouda, Amina ^b   Hays, Constantin ^a   Nordmann, Patrice ^a  

^a BICÊTRE HOSPITAL   (France)

^b Cheikh Zaid International Hospital   (Morocco)

Author keywords

Carbapenemases; Enterobacteriaceae; Plasmids

Indexed keywords

AMIKACIN; AMINOGLYCOSIDE ANTIBIOTIC AGENT; BETA LACTAMASE; BETA LACTAMASE CTX M; BETA LACTAMASE CTX M 15; BETA LACTAMASE NDM 1; BETA LACTAMASE OXA 1; BETA LACTAMASE OXA 9; BETA LACTAMASE SHV; BETA LACTAMASE SHV 1; BETA LACTAMASE SHV 5; BETA LACTAMASE TEM 1; CARBAPENEM; CEPHALOSPORIN; CHLORAMPHENICOL; COLISTIN; FOSFOMYCIN; IMIPENEM; METRONIDAZOLE; NITROFURANTOIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RIFAMPICIN; SULFONAMIDE; TIGECYCLINE; UNCLASSIFIED DRUG;

ADULT; AGED; ANTIBIOTIC RESISTANCE; ANTIBIOTIC THERAPY; ARTICLE; BACTERIUM ISOLATE; CLONAL VARIATION; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; GENE EXPRESSION PROFILING; GENE LOCATION; GENE SEQUENCE; GENE TRANSFER; HOSPITAL PATIENT; HUMAN; KLEBSIELLA PNEUMONIAE; KLEBSIELLA PNEUMONIAE INFECTION; MALE; MEDICAL HISTORY; MICROBIAL SENSITIVITY TEST; MINIMUM INHIBITORY CONCENTRATION; MOROCCO; MULTIDRUG RESISTANCE; MULTILOCUS SEQUENCE TYPING; NONHUMAN; OUTPATIENT; POLYMERASE CHAIN REACTION; PULSED FIELD GEL ELECTROPHORESIS; SEQUENCE ANALYSIS; URINARY TRACT INFECTION; WARD;

AGED; ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; CARBAPENEMS; CLUSTER ANALYSIS; DNA, BACTERIAL; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; FEMALE; GENOTYPE; HOSPITALS; HUMANS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; MALE; MIDDLE AGED; MOROCCO; MULTILOCUS SEQUENCE TYPING; PLASMIDS; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA;

EID: 81855168396     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkr384     Document Type: Article

References (13)

1. Poirel L, Pitout JD, Nordmann P. Carbapenemases: molecular diversity and clinical consequences. Future Microbiol 2007; 2: 501-12.
2. Poirel L, Ros A, Carrër A et al. Cross-border transmission of OXA-48-producing Enterobacter cloacae from Morocco to France. J Antimicrob Chemother 2011; 66: 1181-2.
3. Nordmann P, Poirel L, Toleman MA et al. Does broad-spectrum β-lactam resistance due to NDM-1 herald the end of the antibiotic era for treatment of infections caused by Gram-negative bacteria? J Antimicrob Chemother 2011; 66: 689-92.
4. Kumarasamy KK, Toleman MA, Walsh TR et al. Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study. Lancet Infect Dis 2010; 10: 597-602.
5. Kaase M, Nordmann P, Wichelhaus TA et al. NDM-2 carbapenemase in Acinetobacter baumannii from Egypt. J Antimicrob Chemother 2011; 66: 1260-2.
6. Walsh TR, Weeks J, Livermore DM et al. Dissemination of NDM-1 positive bacteria in the New Delhi environment and its implications for human health: an environmental point prevalence study. Lancet Infect Dis 2011; 11: 355-62.
7. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing: M100-S20U. CLSI, Wayne, PA, USA, 2010.
8. Berçot B, Poirel L, Nordmann P. Plasmid-mediated 16S rRNA methylases among extended-spectrum b-lactamase-producing Enterobacteriaceae isolates. Antimicrob Agents Chemother 2008; 52: 4526-7.
9. Carattoli A, Bertini A, Villa L et al. Identification of plasmids by PCR-based replicon typing. J Microbiol Methods 2005; 63: 219-28.
10. Diancourt L, Passet V, Verhoef J et al. Multilocus sequence typing of Klebsiella pneumoniae nosocomial isolates. J Clin Microbiol 2005; 43: 4178-82.
11. Damjanova I, Tóth A, Pászti J et al. Expansion and countrywide dissemination of ST11, ST15 and ST147 ciprofloxacin-resistant CTX-M-15-type b-lactamase-producing Klebsiella pneumoniae epidemic clones in Hungary in 2005-the new 'MRSAs'? J Antimicrob Chemother 2008; 62: 978-85.
12. Nielsen JB, Skov MN, Jørgensen RL et al. Identification of CTX-M15-, SHV-28-producing Klebsiella pneumoniae ST15 as an epidemic clone in the Copenhagen area using a semi-automated Rep-PCR typing assay. Eur J Clin Microbiol Infect Dis 2011; 30: 773-8.
13. Poirel L, Dortet L, Bernabeu S et al. Genetic features of blaNDM-1-positive Enterobacteriaceae. Antimicrob Agents Chemother 2011; doi:10.1128/AAC.00585-11.