Salt-inducible kinase 3 deficiency exacerbates lipopolysaccharide-induced endotoxin shock accompanied by increased levels of pro-inflammatory molecules in mice

Immunology

Volumn 145, Issue 2, 2015, Pages 268-278

  Sanosaka, Masato ^a   Fujimoto, Minoru ^a   Ohkawara, Tomoharu ^a   Nagatake, Takahiro ^a   Itoh, Yumi ^a   Kagawa, Mai ^a   Kumagai, Ayako ^a   Fuchino, Hiroyuki ^a   Kunisawa, Jun ^a   Naka, Tetsuji ^a   Takemori, Hiroshi ^a  

^a NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

Author keywords

AMP activated protein kinase; Endotoxin shock; Inducible nitric oxide synthase; Interleukin 12p40; Interleukin 1 ; Interleukin 6; Macrophage; Salt inducible kinases; Tumour necrosis factor

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 12P40; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; SALT INDUCIBLE KINASE 3; THIOGLYCOLIC ACID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; AUTACOID; NITRIC OXIDE; PROTEIN SERINE THREONINE KINASE; SIK3 PROTEIN, MOUSE;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW DERIVED MACROPHAGE; BONE MARROW TRANSPLANTATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEATH; DISEASE EXACERBATION; GRAFT RECIPIENT; HEMATOPOIETIC CELL; IMMUNOREGULATION; IN VIVO STUDY; INFLAMMATION; MALE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEPTIC SHOCK; SIGNAL TRANSDUCTION; UPREGULATION; WILD TYPE MOUSE; ANIMAL; CELL LINE; CHEMICALLY INDUCED; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; PATHOLOGY;

ANIMALS; CELL LINE; GENE EXPRESSION REGULATION; INFLAMMATION MEDIATORS; INTERLEUKIN-12 SUBUNIT P40; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES, PERITONEAL; MICE; MICE, KNOCKOUT; NITRIC OXIDE; PROTEIN-SERINE-THREONINE KINASES; SHOCK, SEPTIC; SIGNAL TRANSDUCTION;

EID: 84929658915     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12445     Document Type: Article

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