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Volumn 14, Issue 5, 2015, Pages 2005-2016

Comparison of two different Astragali radix by a 1H NMR-based metabolomic approach

Author keywords

Astragali Radix; chemical differences; metabolic changes; metabolomics; NMR

Indexed keywords

ASTRAGALUS ROOT; HERBACEOUS AGENT; HUANG QI; PLANT EXTRACT;

EID: 84929657838     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr501167u     Document Type: Article
Times cited : (50)

References (49)
  • 2
    • 84862819634 scopus 로고    scopus 로고
    • Effects of dietary Astragalus polysaccharide and Astragalus membranaceus root supplementation on growth performance, rumen fermentation, immune responses, and antioxidant status of lambs
    • Zhong, R.; Yu, M.; Liu, H.; Sun, H.; Cao, Y.; Zhou, D. Effects of dietary Astragalus polysaccharide and Astragalus membranaceus root supplementation on growth performance, rumen fermentation, immune responses, and antioxidant status of lambs Anim. Feed Sci. Technol. 2012, 174 (1) 60-67
    • (2012) Anim. Feed Sci. Technol. , vol.174 , Issue.1 , pp. 60-67
    • Zhong, R.1    Yu, M.2    Liu, H.3    Sun, H.4    Cao, Y.5    Zhou, D.6
  • 3
    • 61449136691 scopus 로고    scopus 로고
    • Studies on principal components and antioxidant activity of different Radix Astragali samples using high-performance liquid chromatography/electrospray ionization multiple-stage tandem mass spectrometry
    • Huang, X.; Liu, Y.; Song, F.; Liu, Z.; Liu, S. Studies on principal components and antioxidant activity of different Radix Astragali samples using high-performance liquid chromatography/electrospray ionization multiple-stage tandem mass spectrometry Talanta 2009, 78 (3) 1090-1101
    • (2009) Talanta , vol.78 , Issue.3 , pp. 1090-1101
    • Huang, X.1    Liu, Y.2    Song, F.3    Liu, Z.4    Liu, S.5
  • 4
    • 77951685464 scopus 로고    scopus 로고
    • Quality evaluation of Radix Astragali from different sources in China
    • Liu, J.; Chen, H.; Zhao, Z. Quality evaluation of Radix Astragali from different sources in China J. Chin. Pharm. Sci. 2009, 18 (1) 6
    • (2009) J. Chin. Pharm. Sci. , vol.18 , Issue.1 , pp. 6
    • Liu, J.1    Chen, H.2    Zhao, Z.3
  • 5
    • 77749320523 scopus 로고    scopus 로고
    • NMR-based metabolomic analysis of plants
    • Kim, H. K.; Choi, Y. H.; Verpoorte, R. NMR-based metabolomic analysis of plants Nat. Protoc. 2010, 5 (3) 536-549
    • (2010) Nat. Protoc. , vol.5 , Issue.3 , pp. 536-549
    • Kim, H.K.1    Choi, Y.H.2    Verpoorte, R.3
  • 6
    • 39149126712 scopus 로고    scopus 로고
    • Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts
    • Beckonert, O.; Keun, H. C.; Ebbels, T. M.; Bundy, J.; Holmes, E.; Lindon, J. C.; Nicholson, J. K. Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts Nat. Protoc. 2007, 2 (11) 2692-2703
    • (2007) Nat. Protoc. , vol.2 , Issue.11 , pp. 2692-2703
    • Beckonert, O.1    Keun, H.C.2    Ebbels, T.M.3    Bundy, J.4    Holmes, E.5    Lindon, J.C.6    Nicholson, J.K.7
  • 7
    • 18744404827 scopus 로고    scopus 로고
    • Metabolic fingerprinting of Ephedra species using 1H-NMR spectroscopy and principal component analysis
    • Kim, H. K.; Choi, Y. H.; Erkelens, C.; Lefeber, A. W.; Verpoorte, R. Metabolic fingerprinting of Ephedra species using 1H-NMR spectroscopy and principal component analysis Chem. Pharm. Bull. 2005, 53 (1) 105-109
    • (2005) Chem. Pharm. Bull. , vol.53 , Issue.1 , pp. 105-109
    • Kim, H.K.1    Choi, Y.H.2    Erkelens, C.3    Lefeber, A.W.4    Verpoorte, R.5
  • 9
    • 79953717774 scopus 로고    scopus 로고
    • Dynamic metabonomic responses of tobacco (Nicotiana tabacum) plants to salt stress
    • Zhang, J.; Zhang, Y.; Du, Y.; Chen, S.; Tang, H. Dynamic metabonomic responses of tobacco (Nicotiana tabacum) plants to salt stress J. Proteome Res. 2011, 10 (4) 1904-1914
    • (2011) J. Proteome Res. , vol.10 , Issue.4 , pp. 1904-1914
    • Zhang, J.1    Zhang, Y.2    Du, Y.3    Chen, S.4    Tang, H.5
  • 11
    • 84897137628 scopus 로고    scopus 로고
    • 1 H NMR based metabolic profiling of the processing effect on Rehmanniae Radix
    • 1 H NMR based metabolic profiling of the processing effect on Rehmanniae Radix Anal. Methods 2014, 6 (8) 2736-2744
    • (2014) Anal. Methods , vol.6 , Issue.8 , pp. 2736-2744
    • He, P.1    Li, Z.-Y.2    Xing, J.3    Qin, X.-M.4    Du, G.-H.5
  • 12
    • 84873339943 scopus 로고    scopus 로고
    • Gallic acid intake induces alterations to systems metabolism in rats
    • Shi, X.; Xiao, C.; Wang, Y.; Tang, H. Gallic acid intake induces alterations to systems metabolism in rats J. Proteome Res. 2012, 12 (2) 991-1006
    • (2012) J. Proteome Res. , vol.12 , Issue.2 , pp. 991-1006
    • Shi, X.1    Xiao, C.2    Wang, Y.3    Tang, H.4
  • 13
    • 12344311533 scopus 로고    scopus 로고
    • A metabonomic strategy for the detection of the metabolic effects of chamomile (Matricaria recutita L.) ingestion
    • Wang, Y.; Tang, H.; Nicholson, J. K.; Hylands, P. J.; Sampson, J.; Holmes, E. A metabonomic strategy for the detection of the metabolic effects of chamomile (Matricaria recutita L.) ingestion J. Agric. Food Chem. 2005, 53 (2) 191-196
    • (2005) J. Agric. Food Chem. , vol.53 , Issue.2 , pp. 191-196
    • Wang, Y.1    Tang, H.2    Nicholson, J.K.3    Hylands, P.J.4    Sampson, J.5    Holmes, E.6
  • 14
    • 80655147179 scopus 로고    scopus 로고
    • Dietary supplementation with L-arginine partially counteracts serum metabonome induced by weaning stress in piglets
    • He, Q.; Tang, H.; Ren, P.; Kong, X.; Wu, G.; Yin, Y.; Wang, Y. Dietary supplementation with L-arginine partially counteracts serum metabonome induced by weaning stress in piglets J. Proteome Res. 2011, 10 (11) 5214-5221
    • (2011) J. Proteome Res. , vol.10 , Issue.11 , pp. 5214-5221
    • He, Q.1    Tang, H.2    Ren, P.3    Kong, X.4    Wu, G.5    Yin, Y.6    Wang, Y.7
  • 16
    • 84879467050 scopus 로고    scopus 로고
    • 1H NMR-Based Metabonomic Investigation of Time-Related Metabolic Trajectories of the Plasma, Urine and Liver Extracts of Hyperlipidemic Hamsters
    • 1H NMR-Based Metabonomic Investigation of Time-Related Metabolic Trajectories of the Plasma, Urine and Liver Extracts of Hyperlipidemic Hamsters PloS One 2013, 8 (6) e66786
    • (2013) PloS One , vol.8 , Issue.6 , pp. 66786
    • Jiang, C.-Y.1    Yang, K.-M.2    Yang, L.3    Miao, Z.-X.4    Wang, Y.-H.5    Zhu, H.-B.6
  • 18
    • 84860386341 scopus 로고    scopus 로고
    • Double-check: Validation of diagnostic statistics for PLS-DA models in metabolomics studies
    • Szymańska, E.; Saccenti, E.; Smilde, A. K.; Westerhuis, J. A. Double-check: validation of diagnostic statistics for PLS-DA models in metabolomics studies Metabolomics 2012, 8 (1) 3-16
    • (2012) Metabolomics , vol.8 , Issue.1 , pp. 3-16
    • Szymańska, E.1    Saccenti, E.2    Smilde, A.K.3    Westerhuis, J.A.4
  • 19
    • 69349089454 scopus 로고    scopus 로고
    • Dimensionality reduction for metabolome data using PCA, PLS, OPLS, and RFDA with differential penalties to latent variables
    • Yamamoto, H.; Yamaji, H.; Abe, Y.; Harada, K.; Waluyo, D.; Fukusaki, E.; Kondo, A.; Ohno, H.; Fukuda, H. Dimensionality reduction for metabolome data using PCA, PLS, OPLS, and RFDA with differential penalties to latent variables Chemom. Intell. Lab. Syst. 2009, 98 (2) 136-142
    • (2009) Chemom. Intell. Lab. Syst. , vol.98 , Issue.2 , pp. 136-142
    • Yamamoto, H.1    Yamaji, H.2    Abe, Y.3    Harada, K.4    Waluyo, D.5    Fukusaki, E.6    Kondo, A.7    Ohno, H.8    Fukuda, H.9
  • 20
    • 34249335649 scopus 로고    scopus 로고
    • OPLS discriminant analysis: Combining the strengths of PLS-DA and SIMCA classification
    • Bylesjö, M.; Rantalainen, M.; Cloarec, O.; Nicholson, J. K.; Holmes, E.; Trygg, J. OPLS discriminant analysis: combining the strengths of PLS-DA and SIMCA classification J. Chemom. 2006, 20 (8-10) 341-351
    • (2006) J. Chemom. , vol.20 , Issue.810 , pp. 341-351
    • Bylesjö, M.1    Rantalainen, M.2    Cloarec, O.3    Nicholson, J.K.4    Holmes, E.5    Trygg, J.6
  • 21
    • 77949334561 scopus 로고    scopus 로고
    • Metabolomics analysis II. Preparation of biological samples prior to detection
    • álvarez-Sánchez, B.; Priego-Capote, F.; Castro, M. Metabolomics analysis II. Preparation of biological samples prior to detection TrAC Trends Anal. Chem. 2010, 29 (2) 120-127
    • (2010) TrAC Trends Anal. Chem. , vol.29 , Issue.2 , pp. 120-127
    • Álvarez-Sánchez, B.1    Priego-Capote, F.2    Castro, M.3
  • 23
    • 84863628151 scopus 로고    scopus 로고
    • Metabonomic analysis reveals the CCl4-induced systems alterations for multiple rat organs
    • Jiang, L.; Huang, J.; Wang, Y.; Tang, H. Metabonomic analysis reveals the CCl4-induced systems alterations for multiple rat organs J. Proteome Res. 2012, 11 (7) 3848-3859
    • (2012) J. Proteome Res. , vol.11 , Issue.7 , pp. 3848-3859
    • Jiang, L.1    Huang, J.2    Wang, Y.3    Tang, H.4
  • 24
    • 84874030013 scopus 로고    scopus 로고
    • Metabolic influence of acute cyadox exposure on Kunming mice
    • Huang, C.; Lei, H.; Zhao, X.; Tang, H.; Wang, Y. Metabolic influence of acute cyadox exposure on Kunming mice J. Proteome Res. 2012, 12 (1) 537-545
    • (2012) J. Proteome Res. , vol.12 , Issue.1 , pp. 537-545
    • Huang, C.1    Lei, H.2    Zhao, X.3    Tang, H.4    Wang, Y.5
  • 25
    • 33751017374 scopus 로고    scopus 로고
    • Quality evaluation of Radix Astragali through a simultaneous determination of six major active isoflavonoids and four main saponins by high-performance liquid chromatography coupled with diode array and evaporative light scattering detectors
    • Qi, L. W.; Yu, Q. T.; Li, P.; Li, S. L.; Wang, Y. X.; Sheng, L. H.; Yi, L. Quality evaluation of Radix Astragali through a simultaneous determination of six major active isoflavonoids and four main saponins by high-performance liquid chromatography coupled with diode array and evaporative light scattering detectors J. Chromatogr. A 2006, 1134 (1) 162-169
    • (2006) J. Chromatogr. A , vol.1134 , Issue.1 , pp. 162-169
    • Qi, L.W.1    Yu, Q.T.2    Li, P.3    Li, S.L.4    Wang, Y.X.5    Sheng, L.H.6    Yi, L.7
  • 26
    • 60349085393 scopus 로고    scopus 로고
    • Application of high-performance liquid chromatography-electrospray ionization time-of-flight mass spectrometry for analysis and quality control of Radix Astragali and its preparations
    • Qi, L. W.; Li, P.; Ren, M. T.; Yu, Q. T.; Wen, X. D.; Wang, Y. X. Application of high-performance liquid chromatography-electrospray ionization time-of-flight mass spectrometry for analysis and quality control of Radix Astragali and its preparations J. Chromatogr. A 2009, 1216 (11) 2087-2097
    • (2009) J. Chromatogr. A , vol.1216 , Issue.11 , pp. 2087-2097
    • Qi, L.W.1    Li, P.2    Ren, M.T.3    Yu, Q.T.4    Wen, X.D.5    Wang, Y.X.6
  • 28
    • 77949803652 scopus 로고    scopus 로고
    • Combined NMR and LC-DAD-MS analysis reveals comprehensive metabonomic variations for three phenotypic cultivars of Salvia Miltiorrhiza Bunge
    • Dai, H.; Xiao, C.; Liu, H.; Hao, F.; Tang, H. Combined NMR and LC-DAD-MS analysis reveals comprehensive metabonomic variations for three phenotypic cultivars of Salvia Miltiorrhiza Bunge J. Proteome Res. 2010, 9 (3) 1565-1578
    • (2010) J. Proteome Res. , vol.9 , Issue.3 , pp. 1565-1578
    • Dai, H.1    Xiao, C.2    Liu, H.3    Hao, F.4    Tang, H.5
  • 29
    • 78549276486 scopus 로고    scopus 로고
    • Influence of climate change on production of secondary chemicals in high altitude medicinal plants: Issues needs immediate attention
    • Gairola, S.; Shariff, N. M.; Bhatt, A.; Kala, C. P. Influence of climate change on production of secondary chemicals in high altitude medicinal plants: Issues needs immediate attention J. Med. Plants Res. 2010, 4 (18) 1825-1829
    • (2010) J. Med. Plants Res. , vol.4 , Issue.18 , pp. 1825-1829
    • Gairola, S.1    Shariff, N.M.2    Bhatt, A.3    Kala, C.P.4
  • 32
    • 0036790113 scopus 로고    scopus 로고
    • Modeling biochemical aspects of energy metabolism in mammals
    • van Milgen, J. Modeling biochemical aspects of energy metabolism in mammals J. Nutr. 2002, 132 (10) 3195-3202
    • (2002) J. Nutr. , vol.132 , Issue.10 , pp. 3195-3202
    • Van Milgen, J.1
  • 33
    • 84884240270 scopus 로고    scopus 로고
    • 1H-NMR-Based Metabonomic Studies on the Anti-Depressant Effect of Genipin in the Chronic Unpredictable Mild Stress Rat Model
    • 1H-NMR-Based Metabonomic Studies on the Anti-Depressant Effect of Genipin in the Chronic Unpredictable Mild Stress Rat Model PloS One 2013, 8 (9) e75721
    • (2013) PloS One , vol.8 , Issue.9 , pp. 75721
    • Tian, J.-S.1    Shi, B.-Y.2    Xiang, H.3    Gao, S.4    Qin, X.-M.5    Du, G.-H.6
  • 34
    • 84907626441 scopus 로고    scopus 로고
    • 1 H NMR based metabolomic study of the antifatigue effect of Astragali Radix
    • Li, Z.-Y.; He, P.; Sun, H.-F.; Qin, X.-M.; Du, G.-H. 1 H NMR based metabolomic study of the antifatigue effect of Astragali Radix Mol. BioSyst. 2014, 10 (11) 3022-3030
    • (2014) Mol. BioSyst. , vol.10 , Issue.11 , pp. 3022-3030
    • Li, Z.-Y.1    He, P.2    Sun, H.-F.3    Qin, X.-M.4    Du, G.-H.5
  • 35
    • 59849128091 scopus 로고    scopus 로고
    • Astragalus membranaceus flavonoids (AMF) ameliorate chronic fatigue syndrome induced by food intake restriction plus forced swimming
    • Kuo, Y.-H.; Tsai, W.-J.; Loke, S.-H.; Wu, T.-S.; Chiou, W.-F. Astragalus membranaceus flavonoids (AMF) ameliorate chronic fatigue syndrome induced by food intake restriction plus forced swimming J. Ethnopharmacol. 2009, 122 (1) 28-34
    • (2009) J. Ethnopharmacol. , vol.122 , Issue.1 , pp. 28-34
    • Kuo, Y.-H.1    Tsai, W.-J.2    Loke, S.-H.3    Wu, T.-S.4    Chiou, W.-F.5
  • 37
    • 79956330533 scopus 로고    scopus 로고
    • In vivo evidence for lactate as a neuronal energy source
    • Wyss, M. T.; Jolivet, R.; Buck, A.; Magistretti, P. J.; Weber, B. In vivo evidence for lactate as a neuronal energy source J. Neurosci. 2011, 31 (20) 7477-7485
    • (2011) J. Neurosci. , vol.31 , Issue.20 , pp. 7477-7485
    • Wyss, M.T.1    Jolivet, R.2    Buck, A.3    Magistretti, P.J.4    Weber, B.5
  • 38
    • 84900461949 scopus 로고    scopus 로고
    • 1H NMR-based metabonomic analysis of the effect of optimized rhubarb aglycone on the plasma and urine metabolic fingerprints of focal cerebral ischemia-reperfusion rats
    • 1H NMR-based metabonomic analysis of the effect of optimized rhubarb aglycone on the plasma and urine metabolic fingerprints of focal cerebral ischemia-reperfusion rats J. Ethnopharmacol. 2014, 154 (1) 65-75
    • (2014) J. Ethnopharmacol. , vol.154 , Issue.1 , pp. 65-75
    • Guan, Q.1    Liang, S.2    Wang, Z.3    Yang, Y.4    Wang, S.5
  • 39
    • 84870295559 scopus 로고    scopus 로고
    • Neuroprotective effect of calycosin on cerebral ischemia and reperfusion injury in rats
    • Guo, C.; Tong, L.; Xi, M.; Yang, H.; Dong, H.; Wen, A. Neuroprotective effect of calycosin on cerebral ischemia and reperfusion injury in rats J. Ethnopharmacol. 2012, 144 (3) 768-774
    • (2012) J. Ethnopharmacol. , vol.144 , Issue.3 , pp. 768-774
    • Guo, C.1    Tong, L.2    Xi, M.3    Yang, H.4    Dong, H.5    Wen, A.6
  • 40
    • 2942596217 scopus 로고    scopus 로고
    • Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia
    • Luo, Y.; Qin, Z.; Hong, Z.; Zhang, X.; Ding, D.; Fu, J.-H.; Zhang, W.-D.; Chen, J. Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia Neurosci. Lett. 2004, 363 (3) 218-223
    • (2004) Neurosci. Lett. , vol.363 , Issue.3 , pp. 218-223
    • Luo, Y.1    Qin, Z.2    Hong, Z.3    Zhang, X.4    Ding, D.5    Fu, J.-H.6    Zhang, W.-D.7    Chen, J.8
  • 41
    • 84906938004 scopus 로고    scopus 로고
    • UPLC-Q/TOF MS standardized Chinese formula Xin-Ke-Shu for the treatment of atherosclerosis in a rabbit model
    • Liu, Y.-T.; Peng, J.-B.; Jia, H.-M.; Cai, D.-Y.; Zhang, H.-W.; Yu, C.-Y.; Zou, Z.-M. UPLC-Q/TOF MS standardized Chinese formula Xin-Ke-Shu for the treatment of atherosclerosis in a rabbit model Phytomedicine 2014, 21 (11) 1364-1372
    • (2014) Phytomedicine , vol.21 , Issue.11 , pp. 1364-1372
    • Liu, Y.-T.1    Peng, J.-B.2    Jia, H.-M.3    Cai, D.-Y.4    Zhang, H.-W.5    Yu, C.-Y.6    Zou, Z.-M.7
  • 42
    • 77952941236 scopus 로고    scopus 로고
    • Metabolomic study of the LDL receptor null mouse fed a high-fat diet reveals profound perturbations in choline metabolism that are shared with ApoE null mice
    • Cheng, K.-K.; Benson, G. M.; Grimsditch, D. C.; Reid, D. G.; Connor, S. C.; Griffin, J. L. Metabolomic study of the LDL receptor null mouse fed a high-fat diet reveals profound perturbations in choline metabolism that are shared with ApoE null mice Physiol. Genomics 2010, 41 (3) 224-231
    • (2010) Physiol. Genomics , vol.41 , Issue.3 , pp. 224-231
    • Cheng, K.-K.1    Benson, G.M.2    Grimsditch, D.C.3    Reid, D.G.4    Connor, S.C.5    Griffin, J.L.6
  • 43
    • 32644451004 scopus 로고    scopus 로고
    • Astragaloside IV from Astragalus membranaceus Shows Cardioprotection during Myocardial Ischemia in vivo and in vitro
    • Zhang, W.-D.; Chen, H.; Zhang, C.; Liu, R.-H.; Li, H.-L.; Chen, H.-Z. Astragaloside IV from Astragalus membranaceus Shows Cardioprotection during Myocardial Ischemia in vivo and in vitro Planta Med. 2006, 72 (01) 4-8
    • (2006) Planta Med. , vol.72 , Issue.1 , pp. 4-8
    • Zhang, W.-D.1    Chen, H.2    Zhang, C.3    Liu, R.-H.4    Li, H.-L.5    Chen, H.-Z.6
  • 44
    • 0344463575 scopus 로고    scopus 로고
    • Effect of flavonoids isolated from Astragalus membrananceus on the changes of endothelial permeability induced by low osmolarity
    • Wu, D. Z.; Fan, Y.; Han, Z. F.; Song, C. Q.; Hu, Z. B. Effect of flavonoids isolated from Astragalus membrananceus on the changes of endothelial permeability induced by low osmolarity Pharmacology and Clinics of Chinese Materia Medica 2000, 16 (4) 16-18
    • (2000) Pharmacology and Clinics of Chinese Materia Medica , vol.16 , Issue.4 , pp. 16-18
    • Wu, D.Z.1    Fan, Y.2    Han, Z.F.3    Song, C.Q.4    Hu, Z.B.5
  • 45
    • 0031709570 scopus 로고    scopus 로고
    • Taurine: Protective properties against ethanol-induced hepatic steatosis and lipid peroxidation during chronic ethanol consumption in rats
    • Kerai, M.; Waterfield, C. J.; Kenyon, S.; Asker, D.; Timbrell, J. Taurine: protective properties against ethanol-induced hepatic steatosis and lipid peroxidation during chronic ethanol consumption in rats Amino Acids 1998, 15 (1-2) 53-76
    • (1998) Amino Acids , vol.15 , Issue.12 , pp. 53-76
    • Kerai, M.1    Waterfield, C.J.2    Kenyon, S.3    Asker, D.4    Timbrell, J.5
  • 46
    • 29144460636 scopus 로고    scopus 로고
    • Effects and mechanisms of crude astragalosides fraction on liver fibrosis in rats
    • Gui, S. Y.; Wei, W.; Wang, H.; Wu, L.; Sun, W. Y.; Chen, W. B.; Wu, C. Y. Effects and mechanisms of crude astragalosides fraction on liver fibrosis in rats J. Ethnopharmacol. 2006, 103 (2) 154-159
    • (2006) J. Ethnopharmacol. , vol.103 , Issue.2 , pp. 154-159
    • Gui, S.Y.1    Wei, W.2    Wang, H.3    Wu, L.4    Sun, W.Y.5    Chen, W.B.6    Wu, C.Y.7
  • 47
    • 0034864352 scopus 로고    scopus 로고
    • Inhibitory effect of total extract of Astragalus on hepatocyte apoptosis
    • Yang, Y.; Chen, M. Z. Inhibitory effect of total extract of Astragalus on hepatocyte apoptosis Chinese Journal of Pharmacology and Toxicology 2001, 15 (4) 287-292
    • (2001) Chinese Journal of Pharmacology and Toxicology , vol.15 , Issue.4 , pp. 287-292
    • Yang, Y.1    Chen, M.Z.2
  • 48
    • 84907922943 scopus 로고    scopus 로고
    • Review of the botanical characteristics, phytochemistry, and pharmacology of Astragalus membranaceus (Huangqi)
    • Fu, J.; Wang, Z.; Huang, L.; Zheng, S.; Wang, D.; Chen, S.; Yang, S. Review of the botanical characteristics, phytochemistry, and pharmacology of Astragalus membranaceus (Huangqi) Phytother. Res. 2014, 28 (9) 1275-1283
    • (2014) Phytother. Res. , vol.28 , Issue.9 , pp. 1275-1283
    • Fu, J.1    Wang, Z.2    Huang, L.3    Zheng, S.4    Wang, D.5    Chen, S.6    Yang, S.7
  • 49
    • 70350340049 scopus 로고    scopus 로고
    • Application of metabonomic analytical techniques in the modernization and toxicology research of traditional Chinese medicine
    • Lao, Y. M.; Jiang, J. G.; Yan, L. Application of metabonomic analytical techniques in the modernization and toxicology research of traditional Chinese medicine Br. J. Pharmacol. 2009, 157 (7) 1128-1141
    • (2009) Br. J. Pharmacol. , vol.157 , Issue.7 , pp. 1128-1141
    • Lao, Y.M.1    Jiang, J.G.2    Yan, L.3


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