Dietary supplementation with L -Arginine partially counteracts serum metabonome induced by weaning Stress in piglets

Journal of Proteome Research

Volumn 10, Issue 11, 2011, Pages 5214-5221

  He, Qinghua ^a   Tang, Huiru ^a   Ren, Pingping ^a   Kong, Xiangfeng ^b   Wu, Guoyao ^b,c   Yin, Yulong ^b   Wang, Yulan ^a  

^a Wuhan National Laboratory for Optoelectronics   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c TEXAS A AND M UNIVERSITY   (United States)

Author keywords

arginine; metabonomics; piglets; serum; weaning stress

Indexed keywords

ALANINE; AMINO ACID; ARGININE; CARBOXYLIC ACID; CHOLINE; GLYCOPROTEIN; LIPOPROTEIN; PROTEOME;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; GROWTH RATE; INTESTINE FLORA; LIPID METABOLISM; MALE; MULTIVARIATE ANALYSIS; NONHUMAN; PIGLET; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RANDOMIZED CONTROLLED TRIAL; STRESS; WEANING; WEIGHT GAIN;

AMINO ACIDS; ANIMALS; ARGININE; DIETARY SUPPLEMENTS; EATING; MAGNETIC RESONANCE SPECTROSCOPY; MALE; METABOLOME; MULTIVARIATE ANALYSIS; ORCHIECTOMY; STRESS, PHYSIOLOGICAL; STRESS, PSYCHOLOGICAL; SUS SCROFA; WEANING; WEIGHT GAIN;

EID: 80655147179     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr200688u     Document Type: Article

References (49)

1. Moeser, A. J.; Ryan, K. A.; Nighot, P. K.; Blikslager, A. T. Gastrointestinal dysfunction induced by early weaning is attenuated by delayed weaning and mast cell blockade in pigs Am. J. Physiol. Gastrointest. Liver Physiol. 2007, 293 (2) G413-421
2. Moeser, A. J.; Klok, C. V.; Ryan, K. A.; Wooten, J. G.; Little, D.; Cook, V. L.; Blikslager, A. T. Stress signaling pathways activated by weaning mediate intestinal dysfunction in the pig Am. J. Physiol. Gastrointest. Liver Physiol. 2007, 292 (1) G173-181
3. Kong, X. F.; Yin, Y. L.; He, Q. H.; Yin, F. G.; Liu, H. J.; Li, T. J.; Huang, R. L.; Geng, M. M.; Ruan, Z.; Deng, Z. Y.; Xie, M. Y.; Wu, G. Dietary supplementation with Chinese herbal powder enhances ileal digestibilities and serum concentrations of amino acids in young pigs Amino Acids 2009, 37 (4) 573-582
4. Smith, F.; Clark, J. E.; Overman, B. L.; Tozel, C. C.; Huang, J. H.; Rivier, J. E.; Blikslager, A. T.; Moeser, A. J. Early weaning stress impairs development of mucosal barrier function in the porcine intestine Am. J. Physiol. Gastrointest. Liver Physiol. 2010, 298 (3) G352-363
5. Lalles, J. P.; Bosi, P.; Smidt, H.; Stokes, C. R. Weaning-A challenge to gut physiologists Livest. Sci. 2007, 108 (1-3) 82-93 (Pubitemid 46654929)
6. Pluske, J. R.; Hampson, D. J.; Williams, I. H. Factors influencing the structure and function of the small intestine in the weaned pig: A review Livest. Prod. Sci. 1997, 51 (1-3) 215-236 (Pubitemid 127395778)
7. Wang, J.; Chen, L.; Li, P.; Li, X.; Zhou, H.; Wang, F.; Li, D.; Yin, Y.; Wu, G. Gene expression is altered in piglet small intestine by weaning and dietary glutamine supplementation J. Nutr. 2008, 138 (6) 1025-1032 (Pubitemid 351769124)
8. Wu, G.; Meier, S. A.; Knabe, D. A. Dietary glutamine supplementation prevents jejunal atrophy in weaned pigs J. Nutr. 1996, 126 (10) 2578-2584 (Pubitemid 26339673)
9. Wu, G.; Knabe, D. A.; Kim, S. W. Arginine nutrition in neonatal pigs J. Nutr. 2004, 134 (10 Suppl) S2783-2790
10. Wu, G.; Bazer, F. W.; Davis, T. A.; Kim, S. W.; Li, P.; Marc Rhoads, J.; Carey Satterfield, M.; Smith, S. B.; Spencer, T. E.; Yin, Y. Arginine metabolism and nutrition in growth, health and disease Amino Acids 2009, 37 (1) 153-168
11. Bohus, E.; Coen, M.; Keun, H. C.; Ebbels, T. M.; Beckonert, O.; Lindon, J. C.; Holmes, E.; Noszal, B.; Nicholson, J. K. Temporal metabonomic modeling of l -arginine-induced exocrine pancreatitis J. Proteome Res. 2008, 7 (10) 4435-4445
12. Tan, B.; Li, X. G.; Kong, X.; Huang, R.; Ruan, Z.; Yao, K.; Deng, Z.; Xie, M.; Shinzato, I.; Yin, Y.; Wu, G. Dietary l -arginine supplementation enhances the immune status in early-weaned piglets Amino Acids 2009, 37 (2) 323-331
13. Yao, K.; Yin, Y. L.; Chu, W.; Liu, Z.; Deng, D.; Li, T.; Huang, R.; Zhang, J.; Tan, B.; Wang, W.; Wu, G. Dietary arginine supplementation increases mTOR signaling activity in skeletal muscle of neonatal pigs J. Nutr. 2008, 138 (5) 867-872 (Pubitemid 351571584)
14. Kim, S. W.; Wu, G. Dietary arginine supplementation enhances the growth of milk-fed young pigs J. Nutr. 2004, 134 (3) 625-630 (Pubitemid 38298507)
15. Zhan, Z.; Ou, D.; Piao, X.; Kim, S. W.; Liu, Y.; Wang, J. Dietary arginine supplementation affects microvascular development in the small intestine of early-weaned pigs J. Nutr. 2008, 138 (7) 1304-1309 (Pubitemid 351930994)
16. Wu, G. Y.; Bazer, F. W.; Davis, T. A.; Jaeger, L. A.; Johnson, G. A.; Kim, S. W.; Knabe, D. A.; Meininger, C. J.; Spencer, T. E.; Yin, Y. L. Important roles for the arginine family of amino acids in swine nutrition and production Livest. Sci. 2007, 112 (1-2) 8-22 (Pubitemid 47516671)
17. Liu, Y.; Huang, J.; Hou, Y.; Zhu, H.; Zhao, S.; Ding, B.; Yin, Y.; Yi, G.; Shi, J.; Fan, W. Dietary arginine supplementation alleviates intestinal mucosal disruption induced by Escherichia coli lipopolysaccharide in weaned pigs Br. J. Nutr. 2008, 100 (3) 552-560
18. Noguchi, Y.; Sakai, R.; Kimura, T. Metabolomics and its potential for assessment of adequacy and safety of amino acid intake J. Nutr. 2003, 133 (6 Suppl 1) S2097-2100
19. Rezzi, S.; Ramadan, Z.; Fay, L. B.; Kochhar, S. Nutritional metabonomics: Applications and perspectives J. Proteome Res. 2007, 6 (2) 513-525 (Pubitemid 46340155)
20. Tang, H. R.; Wang, Y. L. Metabonomics: A revolution in progress Prog. Biophys. Biochem. 2006, 33, 401-417
21. Nicholson, J. K.; Lindon, J. C.; Holmes, E. "Metabonomics: Understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data Xenobiotica 1999, 29 (11) 1181-1189
22. 1H NMR-based metabonomic approach J. Nutr. 2007, 137 (4) 923-929 (Pubitemid 46596888)
23. Wang, Y.; Holmes, E.; Tang, H.; Lindon, J. C.; Sprenger, N.; Turini, M. E.; Bergonzelli, G.; Fay, L. B.; Kochhar, S.; Nicholson, J. K. Experimental metabonomic model of dietary variation and stress interactions J. Proteome Res. 2006, 5 (7) 1535-1542 (Pubitemid 44036127)
24. He, Q.; Kong, X.; Wu, G.; Ren, P.; Tang, H.; Hao, F.; Huang, R.; Li, T.; Tan, B.; Li, P.; Tang, Z.; Yin, Y.; Wu, Y. Metabolomic analysis of the response of growing pigs to dietary l -arginine supplementation Amino Acids 2009, 37 (1) 199-208
25. National Research Council Nutrient Requirements of Swine, 10 th ed.; National Academic Press: Washington, D. C., 1998.
26. Yin, Y. L.; Deng, Z. Y.; Huang, H. L.; Li, T. J.; Zhong, H. Y. The effect of arabinoxylanase and protease supplementation on nutritional value of diets containing wheat bran or rice bran in growing pig J. Anim. Feed Sci. 2004, 13 (3) 445-461 (Pubitemid 39218758)
27. Beckonert, O.; Keun, H. C.; Ebbels, T. M.; Bundy, J.; Holmes, E.; Lindon, J. C.; Nicholson, J. K. Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts Nat. Protoc. 2007, 2 (11) 2692-2703
28. Trygg, J.; Wold, S. Orthogonal projections to latent structures (O-PLS) J. Chemom. 2002, 16 (3) 119-128
29. 1H NMR spectroscopic metabonomic studies Anal. Chem. 2005, 77 (2) 517-526 (Pubitemid 40116831)
30. He, Q.; Ren, P.; Kong, X.; Xu, W.; Tang, H.; Yin, Y.; Wang, Y. Intrauterine growth restriction alters the metabonome of the serum and jejunum in piglets Mol. Biosyst. 2011, 7 (7) 2147-2155
31. 13C NMR spectroscopy of human blood plasma Anal. Chem. 1995, 67 (5) 793-811
32. Zhang, X.; Wang, Y.; Hao, F.; Zhou, X.; Han, X.; Tang, H.; Ji, L. Human serum metabonomic analysis reveals progression axes for glucose intolerance and insulin resistance statuses J. Proteome Res. 2009, 8 (11) 5188-5195
33. Kong, X. F.; Yin, F. G.; He, Q. H.; Liu, H. J.; Li, T. J.; Huang, R. L.; Fan, M. Z.; Liu, Y. L.; Hou, Y. Q.; Li, P.; Ruan, Z.; Deng, Z. Y.; Xie, M. Y.; Xiong, H.; Yin, Y. L. Acanthopanax senticosus extract as a dietary additive enhances the apparent ileal digestibility of amino acids in weaned piglets Livest. Sci. 2009, 123 (2-3) 261-267
34. Zeng, X.; Wang, F.; Fan, X.; Yang, W.; Zhou, B.; Li, P.; Yin, Y.; Wu, G.; Wang, J. Dietary arginine supplementation during early pregnancy enhances embryonic survival in rats J. Nutr. 2008, 138 (8) 1421-1425
35. Jobgen, W.; Meininger, C. J.; Jobgen, S. C.; Li, P.; Lee, M. J.; Smith, S. B.; Spencer, T. E.; Fried, S. K.; Wu, G. Dietary l -arginine supplementation reduces white fat gain and enhances skeletal muscle and brown fat masses in diet-induced obese rats J. Nutr. 2009, 139 (2) 230-237
36. Yao, K.; Guan, S.; Li, T.; Huang, R.; Wu, G.; Ruan, Z.; Yin, Y. Dietary l -arginine supplementation enhances intestinal development and expression of vascular endothelial growth factor in weanling piglets Br. J. Nutr. 2011, 105 (5) 703-709
37. Yoshikawa, K.; Okada, T.; Munakata, S.; Okahashi, A.; Yonezawa, R.; Makimoto, M.; Hosono, S.; Takahashi, S.; Mugishima, H.; Yamamoto, T. Association between serum lipoprotein lipase mass concentration and subcutaneous fat accumulation during neonatal period Eur. J. Clin. Nutr. 2010, 64 (5) 447-453
38. Davies, K. M.; Heaney, R. P.; Rafferty, K. Decline in muscle mass with age in women: A longitudinal study using an indirect measure Metabolism 2002, 51 (7) 935-939 (Pubitemid 34784825)
39. Wang, Y.; Lawler, D.; Larson, B.; Ramadan, Z.; Kochhar, S.; Holmes, E.; Nicholson, J. K. Metabonomic investigations of aging and caloric restriction in a life-long dog study J. Proteome Res. 2007, 6 (5) 1846-1854 (Pubitemid 46814508)
40. Shimomura, Y.; Harris, R. A. Metabolism and physiological function of branched-chain amino acids: Discussion of session 1 J. Nutr. 2006, 136 (1 Suppl) S232-233
41. Grunfeld, C.; Feingold, K. R. HDL and innate immunity: A tale of two apolipoproteins J. Lipid Res. 2008, 49 (8) 1605-1606
42. Khovidhunkit, W.; Kim, M. S.; Memon, R. A.; Shigenaga, J. K.; Moser, A. H.; Feingold, K. R.; Grunfeld, C. Effects of infection and inflammation on lipid and lipoprotein metabolism: Mechanisms and consequences to the host J. Lipid Res. 2004, 45 (7) 1169-1196 (Pubitemid 38802622)
43. al-Waiz, M.; Mikov, M.; Mitchell, S. C.; Smith, R. L. The exogenous origin of trimethylamine in the mouse Metabolism 1992, 41 (2) 135-136
44. Zeisel, S. H.; Wishnok, J. S.; Blusztajn, J. K. Formation of methylamines from ingested choline and lecithin J. Pharmacol. Exp. Ther. 1983, 225 (2) 320-324 (Pubitemid 13091218)
45. Dumas, M. E.; Barton, R. H.; Toye, A.; Cloarec, O.; Blancher, C.; Rothwell, A.; Fearnside, J.; Tatoud, R.; Blanc, V.; Lindon, J. C.; Mitchell, S. C.; Holmes, E.; McCarthy, M. I.; Scott, J.; Gauguier, D.; Nicholson, J. K. Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice Proc. Natl. Acad. Sci. U. S. A. 2006, 103 (33) 12511-12516 (Pubitemid 44267289)
46. Urubschurov, V.; Janczyk, P.; Souffrant, W. B.; Freyer, G.; Zeyner, A. Establishment of intestinal microbiota with focus on yeasts of unweaned and weaned piglets kept under different farm conditions FEMS Microbiol. Ecol. 2011, 77 (3) 493-502
47. Fu, W. J.; Haynes, T. E.; Kohli, R.; Hu, J.; Shi, W.; Spencer, T. E.; Carroll, R. J.; Meininger, C. J.; Wu, G. Dietary l -arginine supplementation reduces fat mass in Zucker diabetic fatty rats J. Nutr. 2005, 135 (4) 714-721 (Pubitemid 40464093)
48. Li, P.; Yin, Y. L.; Li, D.; Kim, S. W.; Wu, G. Amino acids and immune function Br. J. Nutr. 2007, 98 (2) 237-252 (Pubitemid 47091364)
49. Wu, G.; Bazer, F. W.; Datta, S.; Johnson, G. A.; Li, P.; Satterfield, M. C.; Spencer, T. E. Proline metabolism in the conceptus: Implications for fetal growth and development Amino Acids 2008, 35 (4) 691-702