The role of Ctr1 and Ctr2 in mammalian copper homeostasis and platinum-based chemotherapy

Journal of Trace Elements in Medicine and Biology

Volumn 31, Issue , 2015, Pages 178-182

  Öhrvik, Helena ^a   Thiele, Dennis J ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Copper trafficking; Copper transporter, Ctr; Platinum based chemotherapy; Regulation; Structure

Indexed keywords

CARBOPLATIN; CISPLATIN; COPPER; COPPER TRANSPORTER 1; COPPER TRANSPORTER 2; MESSENGER RNA; PLATINUM; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CATION TRANSPORT PROTEIN; PLATINUM COMPLEX; PLATINUM DERIVATIVE; RECOMBINANT PROTEIN; SLC31A1 PROTEIN, HUMAN; SLC31A2 PROTEIN, HUMAN; TUMOR PROTEIN;

ARTICLE; CANCER RESISTANCE; CANCER SURVIVAL; CELL GROWTH; CELL MEMBRANE; CTR2 GENE; DNA SEQUENCE; DRUG EFFICACY; DRUG PROTEIN BINDING; DRUG RESPONSE; ENDOCYTOSIS; GENE; HUMAN; NON SMALL CELL LUNG CANCER; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; SLC31A2 GENE; YEAST CELL; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; COMPARATIVE STUDY; GENE EXPRESSION REGULATION; GENETICS; HOMEOSTASIS; METABOLISM; NEOPLASMS; PROTEIN CONFORMATION; PROTEIN MOTIF; TRANSPORT AT THE CELLULAR LEVEL;

MAMMALIA;

AMINO ACID MOTIFS; ANIMALS; ANTINEOPLASTIC AGENTS; BIOLOGICAL TRANSPORT; CATION TRANSPORT PROTEINS; COPPER; GENE EXPRESSION REGULATION; HOMEOSTASIS; HUMANS; MODELS, BIOLOGICAL; NEOPLASM PROTEINS; NEOPLASMS; ORGANOPLATINUM COMPOUNDS; PLATINUM COMPOUNDS; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; RECOMBINANT PROTEINS;

EID: 84929656629     PISSN: 0946672X     EISSN: 18783252     Source Type: Journal    
DOI: 10.1016/j.jtemb.2014.03.006     Document Type: Article

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