-
2
-
-
29244463365
-
Astrocyte-endothelial interactions at the blood-brain barrier
-
Abbott NJ, Rönnbäck L, Hansson E: Astrocyte-endothelial interactions at the blood-brain barrier. Nat Rev Neurosci 7:41-53, 2006.
-
(2006)
Nat Rev Neurosci
, vol.7
, pp. 41-53
-
-
Abbott, N.J.1
Rönnbäck, L.2
Hansson, E.3
-
3
-
-
80053538365
-
Breast cancer resistance protein and P-glycoprotein in brain cancer: two gatekeepers team up
-
Agarwal S, Hartz AM, Elmquist WF, Bauer B: Breast cancer resistance protein and P-glycoprotein in brain cancer: two gatekeepers team up. Curr Pharm Des 17:2793-2802, 2011.
-
(2011)
Curr Pharm Des
, vol.17
, pp. 2793-2802
-
-
Agarwal, S.1
Hartz, A.M.2
Elmquist, W.F.3
Bauer, B.4
-
4
-
-
84875947090
-
Oncolytic measles virus strains have significant antitumor activity against glioma stem cells
-
Allen C, Opyrchal M, Aderca I, Schroeder MA, Sarkaria JN, Domingo E, et al: Oncolytic measles virus strains have significant antitumor activity against glioma stem cells. Gene Ther 20:444-449, 2013.
-
(2013)
Gene Ther
, vol.20
, pp. 444-449
-
-
Allen, C.1
Opyrchal, M.2
Aderca, I.3
Schroeder, M.A.4
Sarkaria, J.N.5
Domingo, E.6
-
5
-
-
38949156009
-
Oncolytic measles virus strains in the treatment of gliomas
-
(Erratum in Expert Opin Biol Ther 8:855, 2008)
-
Allen C, Paraskevakou G, Liu C, Iankov ID, Msaouel P, Zollman P, et al: Oncolytic measles virus strains in the treatment of gliomas. Expert Opin Biol Ther 8:213-220, 2008 (Erratum in Expert Opin Biol Ther 8:855, 2008).
-
(2008)
Expert Opin Biol Ther
, vol.8
, pp. 213-220
-
-
Allen, C.1
Paraskevakou, G.2
Liu, C.3
Iankov, I.D.4
Msaouel, P.5
Zollman, P.6
-
6
-
-
0026662530
-
Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis
-
Ambudkar SV, Lelong IH, Zhang J, Cardarelli CO, Gottesman MM, Pastan I: Partial purification and reconstitution of the human multidrug-resistance pump: characterization of the drug-stimulatable ATP hydrolysis. Proc Natl Acad Sci U S A 89:8472-8476, 1992.
-
(1992)
Proc Natl Acad Sci U S A
, vol.89
, pp. 8472-8476
-
-
Ambudkar, S.V.1
Lelong, I.H.2
Zhang, J.3
Cardarelli, C.O.4
Gottesman, M.M.5
Pastan, I.6
-
7
-
-
84866695726
-
Controlled ultrasound-induced blood-brain barrier disruption using passive acoustic emissions monitoring
-
Arvanitis CD, Livingstone MS, Vykhodtseva N, McDannold N: Controlled ultrasound-induced blood-brain barrier disruption using passive acoustic emissions monitoring. PLoS ONE 7:e45783, 2012.
-
(2012)
PLoS ONE
, vol.7
-
-
Arvanitis, C.D.1
Livingstone, M.S.2
Vykhodtseva, N.3
McDannold, N.4
-
8
-
-
84877616104
-
Multiple treatments with liposomal doxorubicin and ultrasound-induced disruption of blood-tumor and blood-brain barriers improve outcomes in a rat glioma model
-
Aryal M, Vykhodtseva N, Zhang YZ, Park J, McDannold N: Multiple treatments with liposomal doxorubicin and ultrasound-induced disruption of blood-tumor and blood-brain barriers improve outcomes in a rat glioma model. J Control Release 169:103-111, 2013.
-
(2013)
J Control Release
, vol.169
, pp. 103-111
-
-
Aryal, M.1
Vykhodtseva, N.2
Zhang, Y.Z.3
Park, J.4
McDannold, N.5
-
9
-
-
33747151646
-
Management of malignant glioma: steady progress with multimodal approaches
-
Ashby LS, Ryken TC: Management of malignant glioma: steady progress with multimodal approaches. Neurosurg Focus 20(4):E3, 2006.
-
(2006)
Neurosurg Focus
, vol.20
, Issue.4
, pp. E3
-
-
Ashby, L.S.1
Ryken, T.C.2
-
10
-
-
77956023302
-
Multi-modality safety assessment of blood-brain barrier opening using focused ultrasound and definity microbubbles: a short-term study
-
Baseri B, Choi JJ, Tung YS, Konofagou EE: Multi-modality safety assessment of blood-brain barrier opening using focused ultrasound and definity microbubbles: a short-term study. Ultrasound Med Biol 36:1445-1459, 2010.
-
(2010)
Ultrasound Med Biol
, vol.36
, pp. 1445-1459
-
-
Baseri, B.1
Choi, J.J.2
Tung, Y.S.3
Konofagou, E.E.4
-
11
-
-
84878362421
-
Opening of the blood-brain barrier with an unfocused ultrasound device in rabbits
-
Beccaria K, Canney M, Goldwirt L, Fernandez C, Adam C, Piquet J, et al: Opening of the blood-brain barrier with an unfocused ultrasound device in rabbits. J Neurosurg 119:887-898, 2013.
-
(2013)
J Neurosurg
, vol.119
, pp. 887-898
-
-
Beccaria, K.1
Canney, M.2
Goldwirt, L.3
Fernandez, C.4
Adam, C.5
Piquet, J.6
-
12
-
-
0141620181
-
Structural and functional aspects of the blood-brain barrier
-
Begley DJ, Brightman MW: Structural and functional aspects of the blood-brain barrier. Prog Drug Res 61:39-78, 2003.
-
(2003)
Prog Drug Res
, vol.61
, pp. 39-78
-
-
Begley, D.J.1
Brightman, M.W.2
-
13
-
-
51249091226
-
Recent advances in blood-brain barrier disruption as a CNS delivery strategy
-
Bellavance MA, Blanchette M, Fortin D: Recent advances in blood-brain barrier disruption as a CNS delivery strategy. AAPS J 10:166-177, 2008.
-
(2008)
AAPS J
, vol.10
, pp. 166-177
-
-
Bellavance, M.A.1
Blanchette, M.2
Fortin, D.3
-
14
-
-
84891016613
-
Convection-enhanced delivery and in vivo imaging of polymeric nanoparticles for the treatment of malignant glioma
-
Bernal GM, LaRiviere MJ, Mansour N, Pytel P, Cahill KE, Voce DJ, et al: Convection-enhanced delivery and in vivo imaging of polymeric nanoparticles for the treatment of malignant glioma. Nanomedicine (Lond Print) 10:149-157, 2014.
-
(2014)
Nanomedicine (Lond Print)
, vol.10
, pp. 149-157
-
-
Bernal, G.M.1
LaRiviere, M.J.2
Mansour, N.3
Pytel, P.4
Cahill, K.E.5
Voce, D.J.6
-
15
-
-
84859979641
-
Nanomaterial-mediated CNS delivery of diagnostic and therapeutic agents
-
Biddlestone-Thorpe L, Marchi N, Guo K, Ghosh C, Janigro D, Valerie K, et al: Nanomaterial-mediated CNS delivery of diagnostic and therapeutic agents. Adv Drug Deliv Rev 64:605-613, 2012.
-
(2012)
Adv Drug Deliv Rev
, vol.64
, pp. 605-613
-
-
Biddlestone-Thorpe, L.1
Marchi, N.2
Guo, K.3
Ghosh, C.4
Janigro, D.5
Valerie, K.6
-
16
-
-
0030888267
-
Intracarotid infusion of RMP-7, a bradykinin analog, and transport of gallium-68 ethylenediamine tetraacetic acid into human gliomas
-
Black KL, Cloughesy T, Huang SC, Gobin YP, Zhou Y, Grous J, et al: Intracarotid infusion of RMP-7, a bradykinin analog, and transport of gallium-68 ethylenediamine tetraacetic acid into human gliomas. J Neurosurg 86:603-609, 1997.
-
(1997)
J Neurosurg
, vol.86
, pp. 603-609
-
-
Black, K.L.1
Cloughesy, T.2
Huang, S.C.3
Gobin, Y.P.4
Zhou, Y.5
Grous, J.6
-
17
-
-
70349310264
-
Real-time monitoring of gadolinium diethylenetriamine penta-acetic acid during osmotic blood-brain barrier disruption using magnetic resonance imaging in normal wistar rats
-
Blanchette M, Pellerin M, Tremblay L, Lepage M, Fortin D: Real-time monitoring of gadolinium diethylenetriamine penta-acetic acid during osmotic blood-brain barrier disruption using magnetic resonance imaging in normal wistar rats. Neurosurgery 65:344-351, 2009.
-
(2009)
Neurosurgery
, vol.65
, pp. 344-351
-
-
Blanchette, M.1
Pellerin, M.2
Tremblay, L.3
Lepage, M.4
Fortin, D.5
-
18
-
-
23444437213
-
Convection-enhanced delivery of macromolecules in the brain
-
Bobo RH, Laske DW, Akbasak A, Morrison PF, Dedrick RL, Oldfield EH: Convection-enhanced delivery of macromolecules in the brain. Proc Natl Acad Sci U S A 91:2076-2080, 1994.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 2076-2080
-
-
Bobo, R.H.1
Laske, D.W.2
Akbasak, A.3
Morrison, P.F.4
Dedrick, R.L.5
Oldfield, E.H.6
-
19
-
-
78650961667
-
Safety and maximum tolerated dose of superselective intraarterial cerebral infusion of bevacizumab after osmotic blood-brain barrier disruption for recurrent malignant glioma. Clinical article
-
Boockvar JA, Tsiouris AJ, Hofstetter CP, Kovanlikaya I, Fralin S, Kesavabhotla K, et al: Safety and maximum tolerated dose of superselective intraarterial cerebral infusion of bevacizumab after osmotic blood-brain barrier disruption for recurrent malignant glioma. Clinical article. J Neurosurg 114:624-632, 2011.
-
(2011)
J Neurosurg
, vol.114
, pp. 624-632
-
-
Boockvar, J.A.1
Tsiouris, A.J.2
Hofstetter, C.P.3
Kovanlikaya, I.4
Fralin, S.5
Kesavabhotla, K.6
-
20
-
-
84888241166
-
The role of Gliadel wafers in the treatment of highgrade gliomas
-
Bregy A, Shah AH, Diaz MV, Pierce HE, Ames PL, Diaz D, et al: The role of Gliadel wafers in the treatment of highgrade gliomas. Expert Rev Anticancer Ther 13:1453-1461, 2013.
-
(2013)
Expert Rev Anticancer Ther
, vol.13
, pp. 1453-1461
-
-
Bregy, A.1
Shah, A.H.2
Diaz, M.V.3
Pierce, H.E.4
Ames, P.L.5
Diaz, D.6
-
21
-
-
0028917333
-
Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas
-
Brem H, Piantadosi S, Burger PC, Walker M, Selker R, Vick NA, et al: Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. Lancet 345:1008-1012, 1995.
-
(1995)
Lancet
, vol.345
, pp. 1008-1012
-
-
Brem, H.1
Piantadosi, S.2
Burger, P.C.3
Walker, M.4
Selker, R.5
Vick, N.A.6
-
22
-
-
0033081516
-
Delivering neuroactive molecules from biodegradable microspheres for application in central nervous system disorders
-
Cao X, Schoichet MS: Delivering neuroactive molecules from biodegradable microspheres for application in central nervous system disorders. Biomaterials 20:329-339, 1999.
-
(1999)
Biomaterials
, vol.20
, pp. 329-339
-
-
Cao, X.1
Schoichet, M.S.2
-
23
-
-
23044502688
-
Use of magnetic resonance imaging to assess blood-brain/blood-glioma barrier opening during conformal radiotherapy
-
Cao Y, Tsien CI, Shen Z, Tatro DS, Ten Haken R, Kessler ML, et al: Use of magnetic resonance imaging to assess blood-brain/blood-glioma barrier opening during conformal radiotherapy. J Clin Oncol 23:4127-4136, 2005.
-
(2005)
J Clin Oncol
, vol.23
, pp. 4127-4136
-
-
Cao, Y.1
Tsien, C.I.2
Shen, Z.3
Tatro, D.S.4
Ten Haken, R.5
Kessler, M.L.6
-
24
-
-
84879399902
-
Targeted delivery of antibody-based therapeutic and imaging agents to CNS tumors: crossing the blood-brain barrier divide
-
Chacko AM, Li C, Pryma DA, Brem S, Coukos G, Muzykantov V: Targeted delivery of antibody-based therapeutic and imaging agents to CNS tumors: crossing the blood-brain barrier divide. Expert Opin Drug Deliv 10:907-926, 2013.
-
(2013)
Expert Opin Drug Deliv
, vol.10
, pp. 907-926
-
-
Chacko, A.M.1
Li, C.2
Pryma, D.A.3
Brem, S.4
Coukos, G.5
Muzykantov, V.6
-
25
-
-
84875755046
-
Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth
-
Cheng L, Huang Z, Zhou W, Wu Q, Donnola S, Liu JK, et al: Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth. Cell 153:139-152, 2013.
-
(2013)
Cell
, vol.153
, pp. 139-152
-
-
Cheng, L.1
Huang, Z.2
Zhou, W.3
Wu, Q.4
Donnola, S.5
Liu, J.K.6
-
26
-
-
70349331502
-
A neurosurgeon's guide to stem cells, cancer stem cells, and brain tumor stem cells
-
Cheshier SH, Kalani MY, Lim M, Ailles L, Huhn SL, Weissman IL: A neurosurgeon's guide to stem cells, cancer stem cells, and brain tumor stem cells. Neurosurgery 65:237-250, 2009.
-
(2009)
Neurosurgery
, vol.65
, pp. 237-250
-
-
Cheshier, S.H.1
Kalani, M.Y.2
Lim, M.3
Ailles, L.4
Huhn, S.L.5
Weissman, I.L.6
-
27
-
-
79952976864
-
Convection-enhanced delivery to achieve widespread distribution of viral vectors: predicting clinical implementation
-
Debinski W, Tatter SB: Convection-enhanced delivery to achieve widespread distribution of viral vectors: predicting clinical implementation. Curr Opin Mol Ther 12:647-653, 2010.
-
(2010)
Curr Opin Mol Ther
, vol.12
, pp. 647-653
-
-
Debinski, W.1
Tatter, S.B.2
-
28
-
-
34250177984
-
The blood-brain barrier and cancer: transporters, treatment, and Trojan horses
-
Deeken JF, Löscher W: The blood-brain barrier and cancer: transporters, treatment, and Trojan horses. Clin Cancer Res 13:1663-1674, 2007.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1663-1674
-
-
Deeken, J.F.1
Löscher, W.2
-
29
-
-
84903543845
-
Nanotherapeutic approaches for brain cancer management
-
del Burgo LS, Hernández RM, Orive G, Pedraz JL: Nanotherapeutic approaches for brain cancer management. Nanomedicine (Lond Print) 10:905-919, 2014.
-
(2014)
Nanomedicine (Lond Print)
, vol.10
, pp. 905-919
-
-
del Burgo, L.S.1
Hernández, R.M.2
Orive, G.3
Pedraz, J.L.4
-
30
-
-
84903536534
-
Focused ultrasound delivery of Raman nanoparticles across the blood-brain barrier: potential for targeting experimental brain tumors
-
Diaz RJ, McVeigh PZ, O'Reilly MA, Burrell K, Bebenek M, Smith C, et al: Focused ultrasound delivery of Raman nanoparticles across the blood-brain barrier: potential for targeting experimental brain tumors. Nanomedicine (Lond Print) 10:1075-1087, 2014.
-
(2014)
Nanomedicine (Lond Print)
, vol.10
, pp. 1075-1087
-
-
Diaz, R.J.1
McVeigh, P.Z.2
O'Reilly, M.A.3
Burrell, K.4
Bebenek, M.5
Smith, C.6
-
31
-
-
20044387390
-
Brain pericytes contribute to the induction and up-regulation of blood-brain barrier functions through transforming growth factor-beta production
-
Dohgu S, Takata F, Yamauchi A, Nakagawa S, Egawa T, Naito M, et al: Brain pericytes contribute to the induction and up-regulation of blood-brain barrier functions through transforming growth factor-beta production. Brain Res 1038:208-215, 2005.
-
(2005)
Brain Res
, vol.1038
, pp. 208-215
-
-
Dohgu, S.1
Takata, F.2
Yamauchi, A.3
Nakagawa, S.4
Egawa, T.5
Naito, M.6
-
32
-
-
0034142246
-
Safety and efficacy of a multicenter study using intraarterial chemotherapy in conjunction with osmotic opening of the blood-brain barrier for the treatment of patients with malignant brain tumors
-
Doolittle ND, Miner ME, Hall WA, Siegal T, Jerome E, Osztie E, et al: Safety and efficacy of a multicenter study using intraarterial chemotherapy in conjunction with osmotic opening of the blood-brain barrier for the treatment of patients with malignant brain tumors. Cancer 88:637-647, 2000.
-
(2000)
Cancer
, vol.88
, pp. 637-647
-
-
Doolittle, N.D.1
Miner, M.E.2
Hall, W.A.3
Siegal, T.4
Jerome, E.5
Osztie, E.6
-
33
-
-
67249130759
-
Dual-targeting topotecan liposomes modified with tamoxifen and wheat germ agglutinin significantly improve drug transport across the blood-brain barrier and survival of brain tumorbearing animals
-
Du J, Lu WL, Ying X, Liu Y, Du P, Tian W, et al: Dual-targeting topotecan liposomes modified with tamoxifen and wheat germ agglutinin significantly improve drug transport across the blood-brain barrier and survival of brain tumorbearing animals. Mol Pharm 6:905-917, 2009.
-
(2009)
Mol Pharm
, vol.6
, pp. 905-917
-
-
Du, J.1
Lu, W.L.2
Ying, X.3
Liu, Y.4
Du, P.5
Tian, W.6
-
34
-
-
0011099824
-
Drug metabolizing enzymes in cerebrovascular endothelial cells afford a metabolic protection to the brain
-
el-Bacha RS, Minn A: Drug metabolizing enzymes in cerebrovascular endothelial cells afford a metabolic protection to the brain. Cell Mol Biol (Noisy-le-grand) 45:15-23, 1999.
-
(1999)
Cell Mol Biol (Noisy-le-grand)
, vol.45
, pp. 15-23
-
-
el-Bacha, R.S.1
Minn, A.2
-
35
-
-
0032504604
-
Central analgesic actions of loperamide following transient permeation of the blood brain barrier with Cereport (RMP-7)
-
Emerich DF, Snodgrass P, Pink M, Bloom F, Bartus RT: Central analgesic actions of loperamide following transient permeation of the blood brain barrier with Cereport (RMP-7). Brain Res 801:259-266, 1998.
-
(1998)
Brain Res
, vol.801
, pp. 259-266
-
-
Emerich, D.F.1
Snodgrass, P.2
Pink, M.3
Bloom, F.4
Bartus, R.T.5
-
36
-
-
0035477616
-
Long-term stabilization in patients with malignant glioma after treatment with liposomal doxorubicin
-
Fabel K, Dietrich J, Hau P, Wismeth C, Winner B, Przywara S, et al: Long-term stabilization in patients with malignant glioma after treatment with liposomal doxorubicin. Cancer 92:1936-1942, 2001.
-
(2001)
Cancer
, vol.92
, pp. 1936-1942
-
-
Fabel, K.1
Dietrich, J.2
Hau, P.3
Wismeth, C.4
Winner, B.5
Przywara, S.6
-
37
-
-
50449099720
-
Cytotoxic chemotherapeutic management of newly diagnosed glioblastoma multiforme
-
Fadul CE, Wen PY, Kim L, Olson JJ: Cytotoxic chemotherapeutic management of newly diagnosed glioblastoma multiforme. J Neurooncol 89:339-357, 2008.
-
(2008)
J Neurooncol
, vol.89
, pp. 339-357
-
-
Fadul, C.E.1
Wen, P.Y.2
Kim, L.3
Olson, J.J.4
-
38
-
-
84892918561
-
MDR1 synonymous polymorphisms alter transporter specificity and protein stability in a stable epithelial monolayer
-
Fung KL, Pan J, Ohnuma S, Lund PE, Pixley JN, Kimchi-Sarfaty C, et al: MDR1 synonymous polymorphisms alter transporter specificity and protein stability in a stable epithelial monolayer. Cancer Res 74:598-608, 2014.
-
(2014)
Cancer Res
, vol.74
, pp. 598-608
-
-
Fung, K.L.1
Pan, J.2
Ohnuma, S.3
Lund, P.E.4
Pixley, J.N.5
Kimchi-Sarfaty, C.6
-
39
-
-
75449107968
-
Drug delivery to the brain using surfactant-coated poly(lactide-co-glycolide) nanoparticles: influence of the formulation parameters
-
Gelperina S, Maksimenko O, Khalansky A, Vanchugova L, Shipulo E, Abbasova K, et al: Drug delivery to the brain using surfactant-coated poly(lactide-co-glycolide) nanoparticles: influence of the formulation parameters. Eur J Pharm Biopharm 74:157-163, 2010.
-
(2010)
Eur J Pharm Biopharm
, vol.74
, pp. 157-163
-
-
Gelperina, S.1
Maksimenko, O.2
Khalansky, A.3
Vanchugova, L.4
Shipulo, E.5
Abbasova, K.6
-
40
-
-
84892845602
-
Recent developments and current concepts in medulloblastoma
-
Gerber NU, Mynarek M, von Hoff K, Friedrich C, Resch A, Rutkowski S: Recent developments and current concepts in medulloblastoma. Cancer Treat Rev 40:356-365, 2014.
-
(2014)
Cancer Treat Rev
, vol.40
, pp. 356-365
-
-
Gerber, N.U.1
Mynarek, M.2
von Hoff, K.3
Friedrich, C.4
Resch, A.5
Rutkowski, S.6
-
42
-
-
0025191051
-
Effect of hyperosmotic blood-brain barrier disruption on transcapillary transport in canine brain tumors
-
Groothuis DR, Warkne PC, Molnar P, Lapin GD, Mikhael MA: Effect of hyperosmotic blood-brain barrier disruption on transcapillary transport in canine brain tumors. J Neurosurg 72:441-449, 1990.
-
(1990)
J Neurosurg
, vol.72
, pp. 441-449
-
-
Groothuis, D.R.1
Warkne, P.C.2
Molnar, P.3
Lapin, G.D.4
Mikhael, M.A.5
-
43
-
-
34548664578
-
TAT peptide-modified liposomes provide enhanced gene delivery to intracranial human brain tumor xenografts in nude mice
-
Gupta B, Levchenko TS, Torchilin VP: TAT peptide-modified liposomes provide enhanced gene delivery to intracranial human brain tumor xenografts in nude mice. Oncol Res 16:351-359, 2007.
-
(2007)
Oncol Res
, vol.16
, pp. 351-359
-
-
Gupta, B.1
Levchenko, T.S.2
Torchilin, V.P.3
-
45
-
-
84886101402
-
Toca 511 gene transfer and 5-fluorocytosine in combination with temozolomide demonstrates synergistic therapeutic efficacy in a temozolomide-sensitive glioblastoma model
-
Huang TT, Hlavaty J, Ostertag D, Espinoza FL, Martin B, Petznek H, et al: Toca 511 gene transfer and 5-fluorocytosine in combination with temozolomide demonstrates synergistic therapeutic efficacy in a temozolomide-sensitive glioblastoma model. Cancer Gene Ther 20:544-551, 2013.
-
(2013)
Cancer Gene Ther
, vol.20
, pp. 544-551
-
-
Huang, T.T.1
Hlavaty, J.2
Ostertag, D.3
Espinoza, F.L.4
Martin, B.5
Petznek, H.6
-
46
-
-
10044278240
-
Local and reversible blood-brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications
-
Hynynen K, McDannold N, Sheikov NA, Jolesz FA, Vykhodtseva N: Local and reversible blood-brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications. Neuroimage 24:12-20, 2005.
-
(2005)
Neuroimage
, vol.24
, pp. 12-20
-
-
Hynynen, K.1
McDannold, N.2
Sheikov, N.A.3
Jolesz, F.A.4
Vykhodtseva, N.5
-
47
-
-
1442303754
-
Noninvasive opening of BBB by focused ultrasound
-
Hynynen K, McDannold N, Vykhodtseva N, Jolesz FA: Noninvasive opening of BBB by focused ultrasound. Acta Neurochir Suppl 86:555-558, 2003.
-
(2003)
Acta Neurochir Suppl
, vol.86
, pp. 555-558
-
-
Hynynen, K.1
McDannold, N.2
Vykhodtseva, N.3
Jolesz, F.A.4
-
48
-
-
0034876083
-
Noninvasive MR imaging-guided focal opening of the bloodbrain barrier in rabbits
-
Hynynen K, McDannold N, Vykhodtseva N, Jolesz FA: Noninvasive MR imaging-guided focal opening of the bloodbrain barrier in rabbits. Radiology 220:640-646, 2001.
-
(2001)
Radiology
, vol.220
, pp. 640-646
-
-
Hynynen, K.1
McDannold, N.2
Vykhodtseva, N.3
Jolesz, F.A.4
-
49
-
-
33748483260
-
Focal disruption of the bloodbrain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery
-
Hynynen K, McDannold N, Vykhodtseva N, Raymond S, Weissleder R, Jolesz FA, et al: Focal disruption of the bloodbrain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery. J Neurosurg 105:445-454, 2006.
-
(2006)
J Neurosurg
, vol.105
, pp. 445-454
-
-
Hynynen, K.1
McDannold, N.2
Vykhodtseva, N.3
Raymond, S.4
Weissleder, R.5
Jolesz, F.A.6
-
50
-
-
0028023546
-
Bradykinin selectively opens bloodtumor barrier in experimental brain tumors
-
Inamura T, Black KL: Bradykinin selectively opens bloodtumor barrier in experimental brain tumors. J Cereb Blood Flow Metab 14:862-870, 1994.
-
(1994)
J Cereb Blood Flow Metab
, vol.14
, pp. 862-870
-
-
Inamura, T.1
Black, K.L.2
-
51
-
-
78149461802
-
Focused ultrasound-mediated bbb disruption is associated with an increase in activation of AKT: experimental study in rats
-
Jalali S, Huang Y, Dumont DJ, Hynynen K: Focused ultrasound-mediated bbb disruption is associated with an increase in activation of AKT: experimental study in rats. BMC Neurol 10:114, 2010.
-
(2010)
BMC Neurol
, vol.10
, pp. 114
-
-
Jalali, S.1
Huang, Y.2
Dumont, D.J.3
Hynynen, K.4
-
52
-
-
1842610700
-
The ABC transporter structure and mechanism: perspectives on recent research
-
Jones PM, George AM: The ABC transporter structure and mechanism: perspectives on recent research. Cell Mol Life Sci 61:682-699, 2004.
-
(2004)
Cell Mol Life Sci
, vol.61
, pp. 682-699
-
-
Jones, P.M.1
George, A.M.2
-
53
-
-
84879959476
-
Transcranial passive acoustic mapping with hemispherical sparse arrays using CT-based skull-specific aberration corrections: a simulation study
-
Jones RM, O'Reilly MA, Hynynen K: Transcranial passive acoustic mapping with hemispherical sparse arrays using CT-based skull-specific aberration corrections: a simulation study. Phys Med Biol 58:4981-5005, 2013.
-
(2013)
Phys Med Biol
, vol.58
, pp. 4981-5005
-
-
Jones, R.M.1
O'Reilly, M.A.2
Hynynen, K.3
-
54
-
-
84911410849
-
Cationic surface charge enhances early regional deposition of liposomes after intracarotid injection
-
Joshi S, Singh-Moon R, Wang M, Chaudhuri DB, Ellis JA, Bruce JN, et al: Cationic surface charge enhances early regional deposition of liposomes after intracarotid injection. J Neurooncol 120:489-497, 2014.
-
(2014)
J Neurooncol
, vol.120
, pp. 489-497
-
-
Joshi, S.1
Singh-Moon, R.2
Wang, M.3
Chaudhuri, D.B.4
Ellis, J.A.5
Bruce, J.N.6
-
55
-
-
33645830172
-
A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
-
Juliano RL, Ling V: A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim Biophys Acta 455:152-162, 1976.
-
(1976)
Biochim Biophys Acta
, vol.455
, pp. 152-162
-
-
Juliano, R.L.1
Ling, V.2
-
56
-
-
84881251866
-
Current status of local therapy in malignant gliomas-a clinical review of three selected approaches
-
Juratli TA, Schackert G, Krex D: Current status of local therapy in malignant gliomas-a clinical review of three selected approaches. Pharmacol Ther 139:341-358, 2013.
-
(2013)
Pharmacol Ther
, vol.139
, pp. 341-358
-
-
Juratli, T.A.1
Schackert, G.2
Krex, D.3
-
57
-
-
79951816274
-
Rapid MR-ARFI method for focal spot localization during focused ultrasound therapy
-
Kaye EA, Chen J, Pauly KB: Rapid MR-ARFI method for focal spot localization during focused ultrasound therapy. Magn Reson Med 65:738-743, 2011.
-
(2011)
Magn Reson Med
, vol.65
, pp. 738-743
-
-
Kaye, E.A.1
Chen, J.2
Pauly, K.B.3
-
58
-
-
3242777026
-
Modulation of the blood-brain barrier in oncology: therapeutic opportunities for the treatment of brain tumours?
-
Kemper EM, Boogerd W, Thuis I, Beijnen JH, van Tellingen O: Modulation of the blood-brain barrier in oncology: therapeutic opportunities for the treatment of brain tumours?. Cancer Treat Rev 30:415-423, 2004.
-
(2004)
Cancer Treat Rev
, vol.30
, pp. 415-423
-
-
Kemper, E.M.1
Boogerd, W.2
Thuis, I.3
Beijnen, J.H.4
van Tellingen, O.5
-
59
-
-
33745363524
-
Convection-enhanced delivery of interleukin-13 receptor-directed cytotoxin for malignant glioma therapy
-
Kioi M, Husain SR, Croteau D, Kunwar S, Puri RK: Convection-enhanced delivery of interleukin-13 receptor-directed cytotoxin for malignant glioma therapy. Technol Cancer Res Treat 5:239-250, 2006.
-
(2006)
Technol Cancer Res Treat
, vol.5
, pp. 239-250
-
-
Kioi, M.1
Husain, S.R.2
Croteau, D.3
Kunwar, S.4
Puri, R.K.5
-
60
-
-
71549138796
-
Convectionenhanced delivery of liposomes to primate brain
-
Krauze MT, Forsayeth J, Yin D, Bankiewicz KS: Convectionenhanced delivery of liposomes to primate brain. Methods Enzymol 465:349-362, 2009.
-
(2009)
Methods Enzymol
, vol.465
, pp. 349-362
-
-
Krauze, M.T.1
Forsayeth, J.2
Yin, D.3
Bankiewicz, K.S.4
-
61
-
-
77950952797
-
P-glycoprotein function at the blood-brain barrier in humans can be quantified with the substrate radiotracer 11C-N-desmethyl-loperamide
-
Kreisl WC, Liow JS, Kimura N, Seneca N, Zoghbi SS, Morse CL, et al: P-glycoprotein function at the blood-brain barrier in humans can be quantified with the substrate radiotracer 11C-N-desmethyl-loperamide. J Nucl Med 51:559-566, 2010.
-
(2010)
J Nucl Med
, vol.51
, pp. 559-566
-
-
Kreisl, W.C.1
Liow, J.S.2
Kimura, N.3
Seneca, N.4
Zoghbi, S.S.5
Morse, C.L.6
-
62
-
-
77952461038
-
Convection enhanced delivery of IL13-PE38QQR for treatment of recurrent malignant glioma: presentation of interim findings from ongoing phase 1 studies
-
Kunwar S: Convection enhanced delivery of IL13-PE38QQR for treatment of recurrent malignant glioma: presentation of interim findings from ongoing phase 1 studies. Acta Neurochir Suppl 88:105-111, 2003.
-
(2003)
Acta Neurochir Suppl
, vol.88
, pp. 105-111
-
-
Kunwar, S.1
-
63
-
-
0027421951
-
Cytotoxicity and antitumor effects of growth factor-toxin fusion proteins on human glioblastoma multiforme cells
-
Kunwar S, Pai LH, Pastan I: Cytotoxicity and antitumor effects of growth factor-toxin fusion proteins on human glioblastoma multiforme cells. J Neurosurg 79:569-576, 1993.
-
(1993)
J Neurosurg
, vol.79
, pp. 569-576
-
-
Kunwar, S.1
Pai, L.H.2
Pastan, I.3
-
64
-
-
64049085365
-
The pericyte: cellular regulator of microvascular blood flow
-
Kutcher ME, Herman IM: The pericyte: cellular regulator of microvascular blood flow. Microvasc Res 77:235-246, 2009.
-
(2009)
Microvasc Res
, vol.77
, pp. 235-246
-
-
Kutcher, M.E.1
Herman, I.M.2
-
65
-
-
0022870817
-
Reversal of intrinsic resistance to adriamycin in normal cells by verapamil
-
Lampidis TJ, Krishan A, Planas L, Tapiero H: Reversal of intrinsic resistance to adriamycin in normal cells by verapamil. Cancer Drug Deliv 3:251-259, 1986.
-
(1986)
Cancer Drug Deliv
, vol.3
, pp. 251-259
-
-
Lampidis, T.J.1
Krishan, A.2
Planas, L.3
Tapiero, H.4
-
66
-
-
0025047826
-
Quantitation of blood-brain barrier defect by magnetic resonance imaging and gadolinium-DTPA in patients with multiple sclerosis and brain tumors
-
Larsson HB, Stubgaard M, Frederiksen JL, Jensen M, Henriksen O, Paulson OB: Quantitation of blood-brain barrier defect by magnetic resonance imaging and gadolinium-DTPA in patients with multiple sclerosis and brain tumors. Magn Reson Med 16:117-131, 1990.
-
(1990)
Magn Reson Med
, vol.16
, pp. 117-131
-
-
Larsson, H.B.1
Stubgaard, M.2
Frederiksen, J.L.3
Jensen, M.4
Henriksen, O.5
Paulson, O.B.6
-
67
-
-
77958581311
-
Monitoring blood-brain barrier status in a rat model of glioma receiving therapy: dual injection of lowmolecular-weight and macromolecular MR contrast media
-
Lemasson B, Serduc R, Maisin C, Bouchet A, Coquery N, Robert P, et al: Monitoring blood-brain barrier status in a rat model of glioma receiving therapy: dual injection of lowmolecular-weight and macromolecular MR contrast media. Radiology 257:342-352, 2010.
-
(2010)
Radiology
, vol.257
, pp. 342-352
-
-
Lemasson, B.1
Serduc, R.2
Maisin, C.3
Bouchet, A.4
Coquery, N.5
Robert, P.6
-
68
-
-
0031922531
-
Multidrug resistance in glioblastoma. Chemosensitivity testing and immunohistochemical demonstration of P-glycoprotein
-
Leweke F, Damian MS, Schindler C, Schachenmayr W: Multidrug resistance in glioblastoma. Chemosensitivity testing and immunohistochemical demonstration of P-glycoprotein. Pathol Res Pract 194:149-155, 1998.
-
(1998)
Pathol Res Pract
, vol.194
, pp. 149-155
-
-
Leweke, F.1
Damian, M.S.2
Schindler, C.3
Schachenmayr, W.4
-
69
-
-
84906236133
-
Multifunctional targeting daunorubicin plus quinacrine liposomes, modified by wheat germ agglutinin and tamoxifen, for treating brain glioma and glioma stem cells
-
Li XT, Ju RJ, Li XY, Zeng F, Shi JF, Liu L, et al: Multifunctional targeting daunorubicin plus quinacrine liposomes, modified by wheat germ agglutinin and tamoxifen, for treating brain glioma and glioma stem cells. Oncotarget 5:6497-6511, 2014.
-
(2014)
Oncotarget
, vol.5
, pp. 6497-6511
-
-
Li, X.T.1
Ju, R.J.2
Li, X.Y.3
Zeng, F.4
Shi, J.F.5
Liu, L.6
-
70
-
-
0033938847
-
Claudin-1 and claudin-5 expression and tight junction morphology are altered in blood vessels of hu-man glioblastoma multiforme
-
Liebner S, Fischmann A, Rascher G, Duffner F, Grote EH, Kalbacher H, et al: Claudin-1 and claudin-5 expression and tight junction morphology are altered in blood vessels of hu-man glioblastoma multiforme. Acta Neuropathol 100:323-331, 2000.
-
(2000)
Acta Neuropathol
, vol.100
, pp. 323-331
-
-
Liebner, S.1
Fischmann, A.2
Rascher, G.3
Duffner, F.4
Grote, E.H.5
Kalbacher, H.6
-
71
-
-
77951477367
-
Blood-brain barrier disruption with focused ultrasound enhances delivery of chemotherapeutic drugs for glioblastoma treatment
-
Liu HL, Hua MY, Chen PY, Chu PC, Pan CH, Yang HW, et al: Blood-brain barrier disruption with focused ultrasound enhances delivery of chemotherapeutic drugs for glioblastoma treatment. Radiology 255:415-425, 2010.
-
(2010)
Radiology
, vol.255
, pp. 415-425
-
-
Liu, H.L.1
Hua, M.Y.2
Chen, P.Y.3
Chu, P.C.4
Pan, C.H.5
Yang, H.W.6
-
72
-
-
77956058742
-
Bradykinin increases the permeability of the blood-tumor barrier by the caveolae-mediated transcellular pathway
-
Liu LB, Xue YX, Liu YH: Bradykinin increases the permeability of the blood-tumor barrier by the caveolae-mediated transcellular pathway. J Neurooncol 99:187-194, 2010.
-
(2010)
J Neurooncol
, vol.99
, pp. 187-194
-
-
Liu, L.B.1
Xue, Y.X.2
Liu, Y.H.3
-
73
-
-
79960693179
-
Noninvasive, transient and selective blood-brain barrier opening in non-human primates in vivo
-
Marquet F, Tung YS, Teichert T, Ferrera VP, Konofagou EE: Noninvasive, transient and selective blood-brain barrier opening in non-human primates in vivo. PLoS ONE 6: e22598, 2011.
-
(2011)
PLoS ONE
, vol.6
-
-
Marquet, F.1
Tung, Y.S.2
Teichert, T.3
Ferrera, V.P.4
Konofagou, E.E.5
-
74
-
-
0026100940
-
Expression of P-glycoprotein in human glioma cell lines and surgical glioma specimens
-
Matsumoto T, Tani E, Kaba K, Shindo H, Miyaji K: Expression of P-glycoprotein in human glioma cell lines and surgical glioma specimens. J Neurosurg 74:460-466, 1991.
-
(1991)
J Neurosurg
, vol.74
, pp. 460-466
-
-
Matsumoto, T.1
Tani, E.2
Kaba, K.3
Shindo, H.4
Miyaji, K.5
-
75
-
-
84863952172
-
Temporary disruption of the blood-brain barrier by use of ultrasound and microbubbles: safety and efficacy evaluation in rhesus macaques
-
McDannold N, Arvanitis CD, Vykhodtseva N, Livingstone MS: Temporary disruption of the blood-brain barrier by use of ultrasound and microbubbles: safety and efficacy evaluation in rhesus macaques. Cancer Res 72:3652-3663, 2012.
-
(2012)
Cancer Res
, vol.72
, pp. 3652-3663
-
-
McDannold, N.1
Arvanitis, C.D.2
Vykhodtseva, N.3
Livingstone, M.S.4
-
76
-
-
27744441243
-
MRI-guided targeted blood-brain barrier disruption with focused ultrasound: histological findings in rabbits
-
McDannold N, Vykhodtseva N, Raymond S, Jolesz FA, Hynynen K: MRI-guided targeted blood-brain barrier disruption with focused ultrasound: histological findings in rabbits. Ultrasound Med Biol 31:1527-1537, 2005.
-
(2005)
Ultrasound Med Biol
, vol.31
, pp. 1527-1537
-
-
McDannold, N.1
Vykhodtseva, N.2
Raymond, S.3
Jolesz, F.A.4
Hynynen, K.5
-
77
-
-
67649757597
-
Experimental study on targeted methotrexate delivery to the rabbit brain via magnetic resonance imaging-guided focused ultrasound
-
Mei J, Cheng Y, Song Y, Yang Y, Wang F, Liu Y, et al: Experimental study on targeted methotrexate delivery to the rabbit brain via magnetic resonance imaging-guided focused ultrasound. J Ultrasound Med 28:871-880, 2009.
-
(2009)
J Ultrasound Med
, vol.28
, pp. 871-880
-
-
Mei, J.1
Cheng, Y.2
Song, Y.3
Yang, Y.4
Wang, F.5
Liu, Y.6
-
78
-
-
0036124520
-
Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors
-
Morikawa S, Baluk P, Kaidoh T, Haskell A, Jain RK, Mc-Donald DM: Abnormalities in pericytes on blood vessels and endothelial sprouts in tumors. Am J Pathol 160:985-1000, 2002.
-
(2002)
Am J Pathol
, vol.160
, pp. 985-1000
-
-
Morikawa, S.1
Baluk, P.2
Kaidoh, T.3
Haskell, A.4
Jain, R.K.5
Mc-Donald, D.M.6
-
79
-
-
84858609055
-
The role of BCNU polymer wafers (Gliadel) in the treatment of malignant glioma
-
Nagpal S: The role of BCNU polymer wafers (Gliadel) in the treatment of malignant glioma. Neurosurg Clin N Am 23:289-295, ix, 2012.
-
(2012)
Neurosurg Clin N Am
, vol.23
, pp. 289-295+ix
-
-
Nagpal, S.1
-
80
-
-
0021709580
-
The effect of graded hypertonic intracarotid infusions on drug delivery to experimental RG-2 gliomas
-
Nakagawa H, Groothuis D, Blasberg RG: The effect of graded hypertonic intracarotid infusions on drug delivery to experimental RG-2 gliomas. Neurology 34:1571-1581, 1984.
-
(1984)
Neurology
, vol.34
, pp. 1571-1581
-
-
Nakagawa, H.1
Groothuis, D.2
Blasberg, R.G.3
-
81
-
-
84865820981
-
A dense poly(ethylene glycol) coating improves penetration of large polymeric nanoparticles within brain tissue
-
Nance EA, Woodworth GF, Sailor KA, Shih TY, Xu Q, Swaminathan G, et al: A dense poly(ethylene glycol) coating improves penetration of large polymeric nanoparticles within brain tissue. Sci Transl Med 4:149ra119, 2012.
-
(2012)
Sci Transl Med
, vol.4
-
-
Nance, E.A.1
Woodworth, G.F.2
Sailor, K.A.3
Shih, T.Y.4
Xu, Q.5
Swaminathan, G.6
-
82
-
-
84881186425
-
Characterization of the blood-brain barrier of metastatic and primary malignant neoplasms
-
Nduom EK, Yang C, Merrill MJ, Zhuang Z, Lonser RR: Characterization of the blood-brain barrier of metastatic and primary malignant neoplasms. J Neurosurg 119:427-433, 2013.
-
(2013)
J Neurosurg
, vol.119
, pp. 427-433
-
-
Nduom, E.K.1
Yang, C.2
Merrill, M.J.3
Zhuang, Z.4
Lonser, R.R.5
-
83
-
-
0025866115
-
Primary CNS lymphoma treated with osmotic blood-brain barrier disruption: prolonged survival and preservation of cognitive function
-
Neuwelt EA, Goldman DL, Dahlborg SA, Crossen J, Ramsey F, Roman-Goldstein S, et al: Primary CNS lymphoma treated with osmotic blood-brain barrier disruption: prolonged survival and preservation of cognitive function. J Clin Oncol 9:1580-1590, 1991.
-
(1991)
J Clin Oncol
, vol.9
, pp. 1580-1590
-
-
Neuwelt, E.A.1
Goldman, D.L.2
Dahlborg, S.A.3
Crossen, J.4
Ramsey, F.5
Roman-Goldstein, S.6
-
84
-
-
14844303575
-
Neuroradiographic changes following convection-enhanced delivery of the recombinant cytotoxin interleukin 13-PE38QQR for recurrent malignant glioma
-
Parney IF, Kunwar S, McDermott M, Berger M, Prados M, Cha S, et al: Neuroradiographic changes following convection-enhanced delivery of the recombinant cytotoxin interleukin 13-PE38QQR for recurrent malignant glioma. J Neurosurg 102:267-275, 2005.
-
(2005)
J Neurosurg
, vol.102
, pp. 267-275
-
-
Parney, I.F.1
Kunwar, S.2
McDermott, M.3
Berger, M.4
Prados, M.5
Cha, S.6
-
86
-
-
34250216389
-
Targeted therapy for brain metastases: improving the therapeutic ratio
-
Patel RR, Mehta MP: Targeted therapy for brain metastases: improving the therapeutic ratio. Clin Cancer Res 13:1675-1683, 2007.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1675-1683
-
-
Patel, R.R.1
Mehta, M.P.2
-
87
-
-
20044374196
-
Safety and feasibility of convectionenhanced delivery of Cotara for the treatment of malignant glioma: initial experience in 51 patients
-
Patel SJ, Shapiro WR, Laske DW, Jensen RL, Asher AL, Wessels BW, et al: Safety and feasibility of convectionenhanced delivery of Cotara for the treatment of malignant glioma: initial experience in 51 patients. Neurosurgery 56:1243-1253, 2005.
-
(2005)
Neurosurgery
, vol.56
, pp. 1243-1253
-
-
Patel, S.J.1
Shapiro, W.R.2
Laske, D.W.3
Jensen, R.L.4
Asher, A.L.5
Wessels, B.W.6
-
88
-
-
84905510048
-
The cross-talk between canonical and non-canonical Wnt-dependent pathways regulates P-glycoprotein expression in human blood-brain barrier cells
-
Pinzón-Daza ML, Salaroglio IC, Kopecka J, Garzòn R, Couraud PO, Ghigo D, et al: The cross-talk between canonical and non-canonical Wnt-dependent pathways regulates P-glycoprotein expression in human blood-brain barrier cells. J Cereb Blood Flow Metab 34:1258-1269, 2014.
-
(2014)
J Cereb Blood Flow Metab
, vol.34
, pp. 1258-1269
-
-
Pinzón-Daza, M.L.1
Salaroglio, I.C.2
Kopecka, J.3
Garzòn, R.4
Couraud, P.O.5
Ghigo, D.6
-
89
-
-
0025615466
-
Influence of radiation on the blood-brain barrier and optimum time of chemotherapy
-
Qin DX, Zheng R, Tang J, Li JX, Hu YH: Influence of radiation on the blood-brain barrier and optimum time of chemotherapy. Int J Radiat Oncol Biol Phys 19:1507-1510, 1990.
-
(1990)
Int J Radiat Oncol Biol Phys
, vol.19
, pp. 1507-1510
-
-
Qin, D.X.1
Zheng, R.2
Tang, J.3
Li, J.X.4
Hu, Y.H.5
-
90
-
-
0034047780
-
Intratumoral administration of recombinant circularly permuted interleukin-4-Pseudomonas exotoxin in patients with high-grade glioma
-
Rand RW, Kreitman RJ, Patronas N, Varricchio F, Pastan I, Puri RK: Intratumoral administration of recombinant circularly permuted interleukin-4-Pseudomonas exotoxin in patients with high-grade glioma. Clin Cancer Res 6:2157-2165, 2000.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2157-2165
-
-
Rand, R.W.1
Kreitman, R.J.2
Patronas, N.3
Varricchio, F.4
Pastan, I.5
Puri, R.K.6
-
91
-
-
0034769183
-
Advances in osmotic opening of the bloodbrain barrier to enhance CNS chemotherapy
-
Rapoport SI: Advances in osmotic opening of the bloodbrain barrier to enhance CNS chemotherapy. Expert Opin Investig Drugs 10:1809-1818, 2001.
-
(2001)
Expert Opin Investig Drugs
, vol.10
, pp. 1809-1818
-
-
Rapoport, S.I.1
-
92
-
-
0033974507
-
Osmotic opening of the blood-brain barrier: principles, mechanism, and therapeutic applications
-
Rapoport SI: Osmotic opening of the blood-brain barrier: principles, mechanism, and therapeutic applications. Cell Mol Neurobiol 20:217-230, 2000.
-
(2000)
Cell Mol Neurobiol
, vol.20
, pp. 217-230
-
-
Rapoport, S.I.1
-
93
-
-
0015386106
-
Testing of a hypothesis for osmotic opening of the blood-brain barrier
-
Rapoport SI, Hori M, Klatzo I: Testing of a hypothesis for osmotic opening of the blood-brain barrier. Am J Physiol 223:323-331, 1972.
-
(1972)
Am J Physiol
, vol.223
, pp. 323-331
-
-
Rapoport, S.I.1
Hori, M.2
Klatzo, I.3
-
94
-
-
0022930658
-
Tight-junctional modification as the basis of osmotic opening of the blood-brain barrier
-
Rapoport SI, Robinson PJ: Tight-junctional modification as the basis of osmotic opening of the blood-brain barrier. Ann N Y Acad Sci 481:250-267, 1986.
-
(1986)
Ann N Y Acad Sci
, vol.481
, pp. 250-267
-
-
Rapoport, S.I.1
Robinson, P.J.2
-
95
-
-
0036942718
-
Extracellular matrix and the blood-brain barrier in glioblastoma multiforme: spatial segregation of tenascin and agrin
-
Rascher G, Fischmann A, Kröger S, Duffner F, Grote EH, Wolburg H: Extracellular matrix and the blood-brain barrier in glioblastoma multiforme: spatial segregation of tenascin and agrin. Acta Neuropathol 104:85-91, 2002.
-
(2002)
Acta Neuropathol
, vol.104
, pp. 85-91
-
-
Rascher, G.1
Fischmann, A.2
Kröger, S.3
Duffner, F.4
Grote, E.H.5
Wolburg, H.6
-
96
-
-
0014109002
-
Fine structural localization of a blood-brain barrier to exogenous peroxidase
-
Reese TS, Karnovsky MJ: Fine structural localization of a blood-brain barrier to exogenous peroxidase. J Cell Biol 34:207-217, 1967.
-
(1967)
J Cell Biol
, vol.34
, pp. 207-217
-
-
Reese, T.S.1
Karnovsky, M.J.2
-
97
-
-
0033593855
-
Reversal of P-glycoprotein mediated multidrug resistance by novel anthranilamide derivatives
-
Roe M, Folkes A, Ashworth P, Brumwell J, Chima L, Hunjan S, et al: Reversal of P-glycoprotein mediated multidrug resistance by novel anthranilamide derivatives. Bioorg Med Chem Lett 9:595-600, 1999.
-
(1999)
Bioorg Med Chem Lett
, vol.9
, pp. 595-600
-
-
Roe, M.1
Folkes, A.2
Ashworth, P.3
Brumwell, J.4
Chima, L.5
Hunjan, S.6
-
98
-
-
0028284897
-
The blood-brain barrier: an important concept in neuroimaging
-
Sage MR, Wilson AJ: The blood-brain barrier: an important concept in neuroimaging. AJNR Am J Neuroradiol 15:601-622, 1994.
-
(1994)
AJNR Am J Neuroradiol
, vol.15
, pp. 601-622
-
-
Sage, M.R.1
Wilson, A.J.2
-
99
-
-
10744219583
-
Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malignant brain tumors
-
Sampson JH, Akabani G, Archer GE, Bigner DD, Berger MS, Friedman AH, et al: Progress report of a Phase I study of the intracerebral microinfusion of a recombinant chimeric protein composed of transforming growth factor (TGF)-alpha and a mutated form of the Pseudomonas exotoxin termed PE-38 (TP-38) for the treatment of malignant brain tumors. J Neurooncol 65:27-35, 2003.
-
(2003)
J Neurooncol
, vol.65
, pp. 27-35
-
-
Sampson, J.H.1
Akabani, G.2
Archer, G.E.3
Bigner, D.D.4
Berger, M.S.5
Friedman, A.H.6
-
100
-
-
33747190640
-
Comparison of intratumoral bolus injection and convection-enhanced delivery of radiolabeled antitenascin monoclonal antibodies
-
Sampson JH, Akabani G, Friedman AH, Bigner D, Kunwar S, Berger MS, et al: Comparison of intratumoral bolus injection and convection-enhanced delivery of radiolabeled antitenascin monoclonal antibodies. Neurosurg Focus 20(4):E14, 2006.
-
(2006)
Neurosurg Focus
, vol.20
, Issue.4
, pp. E14
-
-
Sampson, J.H.1
Akabani, G.2
Friedman, A.H.3
Bigner, D.4
Kunwar, S.5
Berger, M.S.6
-
101
-
-
77955608850
-
Poor drug distribution as a possible explanation for the results of the PRECISE trial
-
Sampson JH, Archer G, Pedain C, Wembacher-Schröder E, Westphal M, Kunwar S, et al: Poor drug distribution as a possible explanation for the results of the PRECISE trial. J Neurosurg 113:301-309, 2010.
-
(2010)
J Neurosurg
, vol.113
, pp. 301-309
-
-
Sampson, J.H.1
Archer, G.2
Pedain, C.3
Wembacher-Schröder, E.4
Westphal, M.5
Kunwar, S.6
-
102
-
-
0029589678
-
Pathway across blood-brain barrier opened by the bradykinin agonist, RMP-7
-
Sanovich E, Bartus RT, Friden PM, Dean RL, Le HQ, Brightman MW: Pathway across blood-brain barrier opened by the bradykinin agonist, RMP-7. Brain Res 705:125-135, 1995.
-
(1995)
Brain Res
, vol.705
, pp. 125-135
-
-
Sanovich, E.1
Bartus, R.T.2
Friden, P.M.3
Dean, R.L.4
Le, H.Q.5
Brightman, M.W.6
-
103
-
-
84901342070
-
Peptide carrier-mediated non-covalent delivery of unmodified cisplatin, methotrexate and other agents via intravenous route to the brain
-
Sarkar G, Curran GL, Sarkaria JN, Lowe VJ, Jenkins RB: Peptide carrier-mediated non-covalent delivery of unmodified cisplatin, methotrexate and other agents via intravenous route to the brain. PLoS ONE 9:e97655, 2014.
-
(2014)
PLoS ONE
, vol.9
-
-
Sarkar, G.1
Curran, G.L.2
Sarkaria, J.N.3
Lowe, V.J.4
Jenkins, R.B.5
-
104
-
-
79955860259
-
Mechanism of low-frequency ultrasound in opening blood-tumor barrier by tight junction
-
Shang X, Wang P, Liu Y, Zhang Z, Xue Y: Mechanism of low-frequency ultrasound in opening blood-tumor barrier by tight junction. J Mol Neurosci 43:364-369, 2011.
-
(2011)
J Mol Neurosci
, vol.43
, pp. 364-369
-
-
Shang, X.1
Wang, P.2
Liu, Y.3
Zhang, Z.4
Xue, Y.5
-
105
-
-
45949097554
-
Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endothelium
-
Sheikov N, McDannold N, Sharma S, Hynynen K: Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endothelium. Ultrasound Med Biol 34:1093-1104, 2008.
-
(2008)
Ultrasound Med Biol
, vol.34
, pp. 1093-1104
-
-
Sheikov, N.1
McDannold, N.2
Sharma, S.3
Hynynen, K.4
-
106
-
-
4143081639
-
Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles
-
Sheikov N, McDannold N, Vykhodtseva N, Jolesz F, Hynynen K: Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles. Ultrasound Med Biol 30:979-989, 2004.
-
(2004)
Ultrasound Med Biol
, vol.30
, pp. 979-989
-
-
Sheikov, N.1
McDannold, N.2
Vykhodtseva, N.3
Jolesz, F.4
Hynynen, K.5
-
107
-
-
84906995089
-
Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma
-
Sonabend AM, Carminucci AS, Amendolara B, Bansal M, Leung R, Lei L, et al: Convection-enhanced delivery of etoposide is effective against murine proneural glioblastoma. Neuro Oncol 16:1210-1219, 2014.
-
(2014)
Neuro Oncol
, vol.16
, pp. 1210-1219
-
-
Sonabend, A.M.1
Carminucci, A.S.2
Amendolara, B.3
Bansal, M.4
Leung, R.5
Lei, L.6
-
108
-
-
77954331628
-
High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
-
Stupp R, Tonn JC, Brada M, Pentheroudakis G: High-grade malignant glioma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 21 Suppl 5:v190-v193, 2010.
-
(2010)
Ann Oncol 21 Suppl
, vol.5
, pp. v190-v193
-
-
Stupp, R.1
Tonn, J.C.2
Brada, M.3
Pentheroudakis, G.4
-
109
-
-
33644775686
-
Targeting multidrug resistance in cancer
-
Szakács G, Paterson JK, Ludwig JA, Booth-Genthe C, Gottesman MM: Targeting multidrug resistance in cancer. Nat Rev Drug Discov 5:219-234, 2006.
-
(2006)
Nat Rev Drug Discov
, vol.5
, pp. 219-234
-
-
Szakács, G.1
Paterson, J.K.2
Ludwig, J.A.3
Booth-Genthe, C.4
Gottesman, M.M.5
-
110
-
-
0033756459
-
Transporter-mediated permeation of drugs across the blood-brain barrier
-
Tamai I, Tsuji A: Transporter-mediated permeation of drugs across the blood-brain barrier. J Pharm Sci 89:1371-1388, 2000.
-
(2000)
J Pharm Sci
, vol.89
, pp. 1371-1388
-
-
Tamai, I.1
Tsuji, A.2
-
111
-
-
35948997685
-
Effects of drug efflux on convection-enhanced paclitaxel delivery to malignant gliomas: technical note
-
Tanner PG, Holtmannspotter M, Tonn JC, Goldbrunner R: Effects of drug efflux on convection-enhanced paclitaxel delivery to malignant gliomas: technical note. Neurosurgery 61:E880-E882, 2007.
-
(2007)
Neurosurgery
, vol.61
, pp. E880-E882
-
-
Tanner, P.G.1
Holtmannspotter, M.2
Tonn, J.C.3
Goldbrunner, R.4
-
112
-
-
0023447098
-
Cellular localization of the multidrugresistance gene product P-glycoprotein in normal human tissues
-
Thiebaut F, Tsuruo T, Hamada H, Gottesman MM, Pastan I, Willingham MC: Cellular localization of the multidrugresistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci U S A 84:7735-7738, 1987.
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
113
-
-
0037358040
-
Overcoming multidrug resistance in cancer: an update on the clinical strategy of inhibiting p-glycoprotein
-
Thomas H, Coley HM: Overcoming multidrug resistance in cancer: an update on the clinical strategy of inhibiting p-glycoprotein. Cancer Contr 10:159-165, 2003.
-
(2003)
Cancer Contr
, vol.10
, pp. 159-165
-
-
Thomas, H.1
Coley, H.M.2
-
114
-
-
79955369724
-
Feasibility of noninvasive cavitation-guided blood-brain barrier opening using focused ultrasound and microbubbles in nonhuman primates
-
Tung YS, Marquet F, Teichert T, Ferrera V, Konofagou EE: Feasibility of noninvasive cavitation-guided blood-brain barrier opening using focused ultrasound and microbubbles in nonhuman primates. Appl Phys Lett 98:163704, 2011.
-
(2011)
Appl Phys Lett
, vol.98
-
-
Tung, Y.S.1
Marquet, F.2
Teichert, T.3
Ferrera, V.4
Konofagou, E.E.5
-
115
-
-
34548721638
-
Ultrasound microbubble induced endothelial cell permeability
-
van Wamel A, Kooiman K, Emmer M, ten Cate FJ, Versluis M, de Jong N: Ultrasound microbubble induced endothelial cell permeability. J Control Release 116:e100-e102, 2006.
-
(2006)
J Control Release
, vol.116
, pp. e100-e102
-
-
van Wamel, A.1
Kooiman, K.2
Emmer, M.3
ten Cate, F.J.4
Versluis, M.5
de Jong, N.6
-
116
-
-
33751320464
-
Effects of shear stress on endothelial cells: possible relevance for ultrasound applications
-
VanBavel E: Effects of shear stress on endothelial cells: possible relevance for ultrasound applications. Prog Biophys Mol Biol 93:374-383, 2007.
-
(2007)
Prog Biophys Mol Biol
, vol.93
, pp. 374-383
-
-
VanBavel, E.1
-
117
-
-
33744492332
-
Phase II trial of intravenous lobradimil and carboplatin in childhood brain tumors: a report from the Children's Oncology Group
-
Warren K, Jakacki R, Widemann B, Aikin A, Libucha M, Packer R, et al: Phase II trial of intravenous lobradimil and carboplatin in childhood brain tumors: a report from the Children's Oncology Group. Cancer Chemother Pharmacol 58:343-347, 2006.
-
(2006)
Cancer Chemother Pharmacol
, vol.58
, pp. 343-347
-
-
Warren, K.1
Jakacki, R.2
Widemann, B.3
Aikin, A.4
Libucha, M.5
Packer, R.6
-
118
-
-
1842688920
-
Redistribution of aquaporin-4 in human glioblastoma correlates with loss of agrin immunoreactivity from brain capillary basal laminae
-
Warth A, Kröger S, Wolburg H: Redistribution of aquaporin-4 in human glioblastoma correlates with loss of agrin immunoreactivity from brain capillary basal laminae. Acta Neuropathol 107:311-318, 2004.
-
(2004)
Acta Neuropathol
, vol.107
, pp. 311-318
-
-
Warth, A.1
Kröger, S.2
Wolburg, H.3
-
119
-
-
84903183157
-
Disruption of astrocyte-vascular coupling and the blood-brain barrier by invading glioma cells
-
Watkins S, Robel S, Kimbrough IF, Robert SM, Ellis-Davies G, Sontheimer H: Disruption of astrocyte-vascular coupling and the blood-brain barrier by invading glioma cells. Nat Commun 5:4196, 2014.
-
(2014)
Nat Commun
, vol.5
, pp. 4196
-
-
Watkins, S.1
Robel, S.2
Kimbrough, I.F.3
Robert, S.M.4
Ellis-Davies, G.5
Sontheimer, H.6
-
120
-
-
0041562430
-
Safety, tolerability, and tumor response of IL4-Pseudomonas exotoxin (NBI-3001) in patients with recurrent malignant glioma
-
Weber F, Asher A, Bucholz R, Berger M, Prados M, Chang S, et al: Safety, tolerability, and tumor response of IL4-Pseudomonas exotoxin (NBI-3001) in patients with recurrent malignant glioma. J Neurooncol 64:125-137, 2003.
-
(2003)
J Neurooncol
, vol.64
, pp. 125-137
-
-
Weber, F.1
Asher, A.2
Bucholz, R.3
Berger, M.4
Prados, M.5
Chang, S.6
-
121
-
-
1542787924
-
Local convection enhanced delivery of IL4-Pseudomonas exotoxin (NBI-3001) for treatment of patients with recurrent malignant glioma
-
Weber FW, Floeth F, Asher A, Bucholz R, Berger M, Prados M, et al: Local convection enhanced delivery of IL4-Pseudomonas exotoxin (NBI-3001) for treatment of patients with recurrent malignant glioma. Acta Neurochir Suppl 88:93-103, 2003.
-
(2003)
Acta Neurochir Suppl
, vol.88
, pp. 93-103
-
-
Weber, F.W.1
Floeth, F.2
Asher, A.3
Bucholz, R.4
Berger, M.5
Prados, M.6
-
122
-
-
84875113679
-
Focused ultrasound-induced blood-brain barrier opening to enhance temozolomide delivery for glioblastoma treatment: a preclinical study
-
Wei KC, Chu PC, Wang HY, Huang CY, Chen PY, Tsai HC, et al: Focused ultrasound-induced blood-brain barrier opening to enhance temozolomide delivery for glioblastoma treatment: a preclinical study. PLoS ONE 8:e58995, 2013.
-
(2013)
PLoS ONE
, vol.8
-
-
Wei, K.C.1
Chu, P.C.2
Wang, H.Y.3
Huang, C.Y.4
Chen, P.Y.5
Tsai, H.C.6
-
123
-
-
48249125791
-
Malignant gliomas in adults
-
Wen PY, Kesari S: Malignant gliomas in adults. N Engl J Med 359:492-507, 2008.
-
(2008)
N Engl J Med
, vol.359
, pp. 492-507
-
-
Wen, P.Y.1
Kesari, S.2
-
124
-
-
0029006203
-
Toxicity and efficacy of carboplatin and etoposide in conjunction with disruption of the blood-brain tumor barrier in the treatment of intracranial neoplasms
-
Williams PC, Henner WD, Roman-Goldstein S, Dahlborg SA, Brummett RE, Tableman M, et al: Toxicity and efficacy of carboplatin and etoposide in conjunction with disruption of the blood-brain tumor barrier in the treatment of intracranial neoplasms. Neurosurgery 37:17-28, 1995.
-
(1995)
Neurosurgery
, vol.37
, pp. 17-28
-
-
Williams, P.C.1
Henner, W.D.2
Roman-Goldstein, S.3
Dahlborg, S.A.4
Brummett, R.E.5
Tableman, M.6
-
125
-
-
0036627211
-
Tight junctions of the blood-brain barrier: development, composition and regulation
-
Wolburg H, Lippoldt A: Tight junctions of the blood-brain barrier: development, composition and regulation. Vascul Pharmacol 38:323-337, 2002.
-
(2002)
Vascul Pharmacol
, vol.38
, pp. 323-337
-
-
Wolburg, H.1
Lippoldt, A.2
-
126
-
-
0038819415
-
Localization of claudin-3 in tight junctions of the blood-brain barrier is selectively lost during experimental autoimmune encephalomyelitis and human glioblastoma multiforme
-
Wolburg H, Wolburg-Buchholz K, Kraus J, Rascher-Eggstein G, Liebner S, Hamm S, et al: Localization of claudin-3 in tight junctions of the blood-brain barrier is selectively lost during experimental autoimmune encephalomyelitis and human glioblastoma multiforme. Acta Neuropathol 105:586-592, 2003.
-
(2003)
Acta Neuropathol
, vol.105
, pp. 586-592
-
-
Wolburg, H.1
Wolburg-Buchholz, K.2
Kraus, J.3
Rascher-Eggstein, G.4
Liebner, S.5
Hamm, S.6
-
127
-
-
84904695949
-
Emerging insights into barriers to effective brain tumor therapeutics
-
Woodworth GF, Dunn GP, Nance EA, Hanes J, Brem H: Emerging insights into barriers to effective brain tumor therapeutics. Front Oncol 4:126, 2014.
-
(2014)
Front Oncol
, vol.4
, pp. 126
-
-
Woodworth, G.F.1
Dunn, G.P.2
Nance, E.A.3
Hanes, J.4
Brem, H.5
-
128
-
-
84893342240
-
Convection-enhanced delivery of nanodiamond drug delivery platforms for intracranial tumor treatment
-
Xi G, Robinson E, Mania-Farnell B, Vanin EF, Shim KW, Takao T, et al: Convection-enhanced delivery of nanodiamond drug delivery platforms for intracranial tumor treatment. Nanomedicine (Lond Print) 10:381-391, 2014.
-
(2014)
Nanomedicine (Lond Print)
, vol.10
, pp. 381-391
-
-
Xi, G.1
Robinson, E.2
Mania-Farnell, B.3
Vanin, E.F.4
Shim, K.W.5
Takao, T.6
-
129
-
-
19644375846
-
Knockdown of occludin expression leads to diverse phenotypic alterations in epithelial cells
-
Yu AS, McCarthy KM, Francis SA, McCormack JM, Lai J, Rogers RA, et al: Knockdown of occludin expression leads to diverse phenotypic alterations in epithelial cells. Am J Physiol Cell Physiol 288:C1231-C1241, 2005.
-
(2005)
Am J Physiol Cell Physiol
, vol.288
, pp. C1231-C1241
-
-
Yu, A.S.1
McCarthy, K.M.2
Francis, S.A.3
McCormack, J.M.4
Lai, J.5
Rogers, R.A.6
-
130
-
-
10544254259
-
Quantification and pharmacokinetics of blood-brain barrier disruption in humans
-
Zünkeler B, Carson RE, Olson J, Blasberg RG, DeVroom H, Lutz RJ, et al: Quantification and pharmacokinetics of blood-brain barrier disruption in humans. J Neurosurg 85:1056-1065, 1996.
-
(1996)
J Neurosurg
, vol.85
, pp. 1056-1065
-
-
Zünkeler, B.1
Carson, R.E.2
Olson, J.3
Blasberg, R.G.4
DeVroom, H.5
Lutz, R.J.6
|