Phase II trial of intravenous lobradimil and carboplatin in childhood brain tumors: A report from the Children's Oncology Group

Cancer Chemotherapy and Pharmacology

Volumn 58, Issue 3, 2006, Pages 343-347

  Warren, K ^a   Jakacki, R ^b   Widemann, B ^a   Aikin, A ^a   Libucha, M ^a   Packer, R ^b   Vezina, G ^b   Reaman, G ^c   Shaw, D ^c   Krailo, M ^c   Osborne, C ^d   Cehelsky, J ^d   Caldwell, D ^d   Stanwood, J ^d   Steinberg, S M ^a   Balis, F M ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^c CHILDREN S ONCOLOGY GROUP   (United States)

^d ALKERMES INC   (United States)

Author keywords

Brain tumors; Children; Ependymoma; Glioma; Lobradimil; Medulloblastoma; Phase II; RMP 7

Indexed keywords

BRADYKININ DERIVATIVE; CARBOPLATIN; LOBRADIMIL; LOMUSTINE; PROCARBAZINE; TIOGUANINE; VINCRISTINE;

ADOLESCENT; ADULT; ANEMIA; AREA UNDER THE CURVE; ARTICLE; BLOOD BRAIN BARRIER; BONE MARROW SUPPRESSION; BRAIN STEM GLIOMA; BRAIN STEM TUMOR; BRAIN TUMOR; CANCER COMBINATION CHEMOTHERAPY; CANCER GRADING; CANCER GROWTH; CHEMOTHERAPY INDUCED EMESIS; CHILD; CHILDHOOD CANCER; CLINICAL ARTICLE; CLINICAL TRIAL; COHORT ANALYSIS; DRUG PENETRATION; EPENDYMOMA; FEMALE; GLIOMA; HEADACHE; HOT FLUSH; HUMAN; HYPOTENSION; MALE; MEDULLOBLASTOMA; NAUSEA; NEUROECTODERM TUMOR; NEUROEPITHELIOMA; NEUTROPENIA; OTOTOXICITY; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; SEIZURE; STOMACH PAIN; SYNCOPE; THROMBOCYTOPENIA; TREATMENT RESPONSE;

ADOLESCENT; ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BLOOD-BRAIN BARRIER; BRADYKININ; BRAIN NEOPLASMS; CARBOPLATIN; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; DRUG ADMINISTRATION SCHEDULE; HUMANS; INFUSIONS, INTRAVENOUS; TREATMENT OUTCOME;

EID: 33744492332     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-005-0172-7     Document Type: Article

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