Cigarette smoke-induced damage-associated molecular pattern release from necrotic neutrophils triggers proinflammatory mediator release

American Journal of Respiratory Cell and Molecular Biology

Volumn 52, Issue 5, 2015, Pages 554-562

  Heijink, Irene H ^a   Pouwels, Simon D ^a   Leijendekker, Carin ^a   De Bruin, Harold G ^a   Zijlstra, G Jan ^a   Van Der Vaart, Hester ^a   Ten Hacken, Nick H T ^a   Van Oosterhout, Antoon J M ^a   Nawijn, Martijn C ^a   Van Der Toorn, Marco ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Chronic obstructive pulmonary disease; Cigarette smoke; Damage associated molecular patterns; Inflammation; Neutrophils

Indexed keywords

ADENOSINE TRIPHOSPHATE; CASPASE 3; CASPASE 7; CIGARETTE SMOKE; DOUBLE STRANDED DNA; HIGH MOBILITY GROUP B1 PROTEIN; INTERLEUKIN 8; MITOCHONDRIAL DNA; MYELOPEROXIDASE; AUTACOID; HMGB1 PROTEIN, MOUSE; IL8 PROTEIN, HUMAN; PEROXIDASE; SMOKE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; CELL DEATH; CELLULAR PARAMETERS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DAMAGE ASSOCIATED MOLECULAR PATTERN; ENZYME ACTIVITY; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; INNATE IMMUNITY; LUNG LAVAGE; MEDIATOR RELEASE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NEUTROPHIL; NEUTROPHIL COUNT; NONHUMAN; NORMAL HUMAN; SMOKING; SPUTUM; SUPERNATANT; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; CELL CULTURE; CROSSOVER PROCEDURE; EXPOSURE; IMMUNOLOGY; LUNG; METABOLISM; NECROSIS; PATHOLOGY; PHENOTYPE; PNEUMONIA; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT MUCOSA; SIGNAL TRANSDUCTION; SMOKE; TIME;

MUS;

ANIMALS; APOPTOSIS; BRONCHOALVEOLAR LAVAGE FLUID; CELLS, CULTURED; CROSS-OVER STUDIES; FEMALE; HMGB1 PROTEIN; HUMANS; IMMUNITY, INNATE; INFLAMMATION MEDIATORS; INHALATION EXPOSURE; INTERLEUKIN-8; LUNG; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE, INBRED C57BL; NECROSIS; NEUTROPHILS; PEROXIDASE; PHENOTYPE; PNEUMONIA; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION; SMOKE; SMOKING; SPUTUM; TIME FACTORS;

EID: 84929484931     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2013-0505OC     Document Type: Article

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