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Volumn 17, Issue 7, 2015, Pages

New Research on Anxiety Disorders in the Elderly and an Update on Evidence-Based Treatments

Author keywords

Anxiety disorders; Elderly; Evidence based treatment; Neurobiological research

Indexed keywords

ANXIOLYTIC AGENT; BENZODIAZEPINE; BUSPIRONE; DULOXETINE; ESCITALOPRAM; MIRTAZAPINE; MONOAMINE OXIDASE INHIBITOR; NEUROLEPTIC AGENT; PLACEBO; PREGABALIN; QUETIAPINE; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TRICYCLIC ANTIDEPRESSANT AGENT; VENLAFAXINE;

EID: 84929415569     PISSN: 15233812     EISSN: 15351645     Source Type: Journal    
DOI: 10.1007/s11920-015-0595-8     Document Type: Review
Times cited : (59)

References (92)
  • 1
    • 0028156958 scopus 로고
    • Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey
    • COI: 1:STN:280:DyaK2c7gslSrtA%3D%3D, PID: 8279933
    • Kessler RC, McGonagle KA, Zhao S, et al. Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey. Arch Gen Psychiatry. 1994;51(1):8–19.
    • (1994) Arch Gen Psychiatry , vol.51 , Issue.1 , pp. 8-19
    • Kessler, R.C.1    McGonagle, K.A.2    Zhao, S.3
  • 2
    • 0030892633 scopus 로고    scopus 로고
    • Epidemiology and comorbidity of anxiety disorders in later life: implications for treatment
    • COI: 1:STN:280:DyaK2s3gvFWkug%3D%3D, PID: 9056120
    • Flint AJ. Epidemiology and comorbidity of anxiety disorders in later life: implications for treatment. Clin Neurosci. 1997;4(1):31–6.
    • (1997) Clin Neurosci , vol.4 , Issue.1 , pp. 31-36
    • Flint, A.J.1
  • 3
    • 16844382282 scopus 로고    scopus 로고
    • Age at onset of generalized anxiety disorder in older adults
    • PID: 15653937
    • Le Roux H, Gatz M, Wetherell JL. Age at onset of generalized anxiety disorder in older adults. Am J Geriatr Psychiatry. 2005;13(1):23–30.
    • (2005) Am J Geriatr Psychiatry , vol.13 , Issue.1 , pp. 23-30
    • Le Roux, H.1    Gatz, M.2    Wetherell, J.L.3
  • 4
    • 0034970411 scopus 로고    scopus 로고
    • Generalized anxiety disorder: nature and course
    • PID: 11414546, discussion 20–11
    • Wittchen HU, Hoyer J. Generalized anxiety disorder: nature and course. J Clin Psychiatry. 2001;62 Suppl 11:15–9. discussion 20–11.
    • (2001) J Clin Psychiatry , vol.62 , pp. 15-19
    • Wittchen, H.U.1    Hoyer, J.2
  • 5
    • 0031721919 scopus 로고    scopus 로고
    • Anxiety disorders in later life: a report from the Longitudinal Aging Study Amsterdam
    • COI: 1:STN:280:DyaK1M%2FjsFOitg%3D%3D, PID: 9818308
    • Beekman AT, Bremmer MA, Deeg DJ, et al. Anxiety disorders in later life: a report from the Longitudinal Aging Study Amsterdam. Int J Geriatr Psychiatry. 1998;13(10):717–26.
    • (1998) Int J Geriatr Psychiatry , vol.13 , Issue.10 , pp. 717-726
    • Beekman, A.T.1    Bremmer, M.A.2    Deeg, D.J.3
  • 6
    • 20144378599 scopus 로고    scopus 로고
    • The outcome of anxiety disorders in older people at 6-year follow-up: results from the Longitudinal Aging Study Amsterdam
    • COI: 1:STN:280:DC%2BD2M3ktVWlsQ%3D%3D, PID: 15877708
    • Schuurmans J, Comijs HC, Beekman AT, et al. The outcome of anxiety disorders in older people at 6-year follow-up: results from the Longitudinal Aging Study Amsterdam. Acta Psychiatr Scand. 2005;111(6):420–8.
    • (2005) Acta Psychiatr Scand , vol.111 , Issue.6 , pp. 420-428
    • Schuurmans, J.1    Comijs, H.C.2    Beekman, A.T.3
  • 7
    • 0023787325 scopus 로고
    • One-month prevalence of mental disorders in the United States. Based on five Epidemiologic Catchment Area sites
    • COI: 1:STN:280:DyaL1M%2FisFSgtA%3D%3D, PID: 3263101
    • Regier DA, Boyd JH, Burke Jr JD, et al. One-month prevalence of mental disorders in the United States. Based on five Epidemiologic Catchment Area sites. Arch Gen Psychiatry. 1988;45(11):977–86.
    • (1988) Arch Gen Psychiatry , vol.45 , Issue.11 , pp. 977-986
    • Regier, D.A.1    Boyd, J.H.2    Burke, J.D.3
  • 8
    • 0036012849 scopus 로고    scopus 로고
    • DSM-IV generalized anxiety disorder in the Australian National Survey of Mental Health and Well-Being
    • COI: 1:STN:280:DC%2BD38zlvV2qsQ%3D%3D, PID: 12102379
    • Hunt C, Issakidis C, Andrews G. DSM-IV generalized anxiety disorder in the Australian National Survey of Mental Health and Well-Being. Psychol Med. 2002;32(4):649–59.
    • (2002) Psychol Med , vol.32 , Issue.4 , pp. 649-659
    • Hunt, C.1    Issakidis, C.2    Andrews, G.3
  • 9
    • 84908152632 scopus 로고    scopus 로고
    • Generalized anxiety in community-dwelling elderly: prevalence and clinical characteristics
    • PID: 25451391, Recent epidemiologic study on a large sample, showing a high prevalence of late-life GAD
    • Zhang X, Norton J, Carriere I, Ritchie K, Chaudieu I, Ancelin ML. Generalized anxiety in community-dwelling elderly: prevalence and clinical characteristics. J Affect Disord. 2014;172C:24–9. Recent epidemiologic study on a large sample, showing a high prevalence of late-life GAD.
    • (2014) J Affect Disord , vol.172C , pp. 24-29
    • Zhang, X.1    Norton, J.2    Carriere, I.3    Ritchie, K.4    Chaudieu, I.5    Ancelin, M.L.6
  • 10
    • 45849146979 scopus 로고    scopus 로고
    • The prevalence of anxiety in older adults: methodological issues and a review of the literature
    • PID: 18155775
    • Bryant C, Jackson H, Ames D. The prevalence of anxiety in older adults: methodological issues and a review of the literature. J Affect Disord. 2008;109(3):233–50.
    • (2008) J Affect Disord , vol.109 , Issue.3 , pp. 233-250
    • Bryant, C.1    Jackson, H.2    Ames, D.3
  • 11
    • 84893788534 scopus 로고    scopus 로고
    • Lambiase MJ, Kubzansky LD, Thurston RC. Prospective study of anxiety and incident stroke. Stroke. 2014;45:438–43. Methodologically sound prospective study showing that higher anxiety symptom levels were associated with increased risk of incident stroke independent of other risk factors, including depression
    • Lambiase MJ, Kubzansky LD, Thurston RC. Prospective study of anxiety and incident stroke. Stroke. 2014;45:438–43. Methodologically sound prospective study showing that higher anxiety symptom levels were associated with increased risk of incident stroke independent of other risk factors, including depression.
  • 12
    • 84886725611 scopus 로고    scopus 로고
    • A review of the affects of worry and generalized anxiety disorder upon cardiovascular health and coronary heart disease
    • PID: 23324073
    • Tully PJ, Cosh SM, Baune BT. A review of the affects of worry and generalized anxiety disorder upon cardiovascular health and coronary heart disease. Psychol Health Med. 2013;18(6):627–44.
    • (2013) Psychol Health Med , vol.18 , Issue.6 , pp. 627-644
    • Tully, P.J.1    Cosh, S.M.2    Baune, B.T.3
  • 13
    • 85027941701 scopus 로고    scopus 로고
    • The association of neuropsychiatric symptoms in MCI with incident dementia and Alzheimer disease
    • PID: 23567400, Recent study on a large sample (1,821 participants with MCI) showing that anxiety symptoms were associated with increased risk of incident dementia
    • Rosenberg PB, Mielke MM, Appleby BS, Oh ES, Geda YE, Lyketsos CG. The association of neuropsychiatric symptoms in MCI with incident dementia and Alzheimer disease. Am J Geriatr Psychiatry. 2013;21(7):685–95. Recent study on a large sample (1,821 participants with MCI) showing that anxiety symptoms were associated with increased risk of incident dementia.
    • (2013) Am J Geriatr Psychiatry , vol.21 , Issue.7 , pp. 685-695
    • Rosenberg, P.B.1    Mielke, M.M.2    Appleby, B.S.3    Oh, E.S.4    Geda, Y.E.5    Lyketsos, C.G.6
  • 14
    • 84989354990 scopus 로고    scopus 로고
    • Risk factors for late-onset generalized anxiety disorder: results from a 12-year prospective cohort (The ESPRIT study)
    • Zhang X, Norton J, Carriere I, Ritchie K, Chaudieu I, Ancelin ML. Risk factors for late-onset generalized anxiety disorder: results from a 12-year prospective cohort (The ESPRIT study). Translat Psychiatry. 2015;5. e536.
    • (2015) Translat Psychiatry , vol.e536 , pp. 5
    • Zhang, X.1    Norton, J.2    Carriere, I.3    Ritchie, K.4    Chaudieu, I.5    Ancelin, M.L.6
  • 15
    • 80054032563 scopus 로고    scopus 로고
    • Deficient prefrontal attentional control in late-life generalized anxiety disorder: an fMRI investigation
    • Price RB, Eldreth DA, Mohlman J. Deficient prefrontal attentional control in late-life generalized anxiety disorder: an fMRI investigation. Translat Psychiatry. 2011;1. e46.
    • (2011) Translat Psychiatry , vol.e46 , pp. 1
    • Price, R.B.1    Eldreth, D.A.2    Mohlman, J.3
  • 16
    • 67651113812 scopus 로고    scopus 로고
    • The relation of worry to prefrontal cortex volume in older adults with and without generalized anxiety disorder
    • PID: 19559575
    • Mohlman J, Price RB, Eldreth DA, Chazin D, Glover DM, Kates WR. The relation of worry to prefrontal cortex volume in older adults with and without generalized anxiety disorder. Psychiatry Res. 2009;173(2):121–7.
    • (2009) Psychiatry Res , vol.173 , Issue.2 , pp. 121-127
    • Mohlman, J.1    Price, R.B.2    Eldreth, D.A.3    Chazin, D.4    Glover, D.M.5    Kates, W.R.6
  • 17
    • 79952608431 scopus 로고    scopus 로고
    • Altered cerebral blood flow patterns associated with pathologic worry in the elderly
    • PID: 21394853
    • Andreescu C, Gross JJ, Lenze E, et al. Altered cerebral blood flow patterns associated with pathologic worry in the elderly. Depress Anxiety. 2011;28(3):202–9.
    • (2011) Depress Anxiety , vol.28 , Issue.3 , pp. 202-209
    • Andreescu, C.1    Gross, J.J.2    Lenze, E.3
  • 18
    • 84928070956 scopus 로고    scopus 로고
    • Emotion reactivity and regulation in late-life generalized anxiety disorder: functional connectivity at baseline and post-treatment
    • PID: 24996397
    • Andreescu C, Sheu LK, Tudorascu D, et al. Emotion reactivity and regulation in late-life generalized anxiety disorder: functional connectivity at baseline and post-treatment. Am J Geriatr Psychiatry. 2015;23(2):200–14.
    • (2015) Am J Geriatr Psychiatry , vol.23 , Issue.2 , pp. 200-214
    • Andreescu, C.1    Sheu, L.K.2    Tudorascu, D.3
  • 19
    • 35748963237 scopus 로고    scopus 로고
    • Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia
    • PID: 17898336
    • Etkin A, Wager TD. Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia. Am J Psychiatry. 2007;164(10):1476–88.
    • (2007) Am J Psychiatry , vol.164 , Issue.10 , pp. 1476-1488
    • Etkin, A.1    Wager, T.D.2
  • 20
    • 62949210618 scopus 로고    scopus 로고
    • Anticipatory activation in the amygdala and anterior cingulate in generalized anxiety disorder and prediction of treatment response
    • PID: 19122007
    • Nitschke JB, Sarinopoulos I, Oathes DJ, et al. Anticipatory activation in the amygdala and anterior cingulate in generalized anxiety disorder and prediction of treatment response. Am J Psychiatry. 2009;166(3):302–10.
    • (2009) Am J Psychiatry , vol.166 , Issue.3 , pp. 302-310
    • Nitschke, J.B.1    Sarinopoulos, I.2    Oathes, D.J.3
  • 21
    • 73149112624 scopus 로고    scopus 로고
    • Disrupted amygdalar subregion functional connectivity and evidence of a compensatory network in generalized anxiety disorder
    • PID: 19996041
    • Etkin A, Prater KE, Schatzberg AF, Menon V, Greicius MD. Disrupted amygdalar subregion functional connectivity and evidence of a compensatory network in generalized anxiety disorder. Arch Gen Psychiatry. 2009;66(12):1361–72.
    • (2009) Arch Gen Psychiatry , vol.66 , Issue.12 , pp. 1361-1372
    • Etkin, A.1    Prater, K.E.2    Schatzberg, A.F.3    Menon, V.4    Greicius, M.D.5
  • 22
    • 84928070956 scopus 로고    scopus 로고
    • Emotion reactivity and regulation in late-life generalized anxiety disorder: functional connectivity at baseline and post-treatment
    • Andreescu C, Sheu LK, Tudorascu D, Gross JJ, Walker S, Banihashemi L, et al. Emotion reactivity and regulation in late-life generalized anxiety disorder: functional connectivity at baseline and post-treatment. Am J Geriatr Psychiatry. 2014.
    • (2014) Am J Geriatr Psychiatry
    • Andreescu, C.1    Sheu, L.K.2    Tudorascu, D.3    Gross, J.J.4    Walker, S.5    Banihashemi, L.6
  • 23
    • 34547918348 scopus 로고    scopus 로고
    • Translational research in late-life mood disorders: implications for future intervention and prevention research
    • COI: 1:CAS:528:DC%2BD2sXptVWis7c%3D, PID: 17327888
    • Smith GS, Gunning-Dixon FM, Lotrich FE, Taylor WD, Evans JD. Translational research in late-life mood disorders: implications for future intervention and prevention research. Neuropsychopharmacology. 2007;32(9):1857–75.
    • (2007) Neuropsychopharmacology , vol.32 , Issue.9 , pp. 1857-1875
    • Smith, G.S.1    Gunning-Dixon, F.M.2    Lotrich, F.E.3    Taylor, W.D.4    Evans, J.D.5
  • 24
    • 84902282685 scopus 로고    scopus 로고
    • The ages of anxiety—differences across the lifespan in the default mode network functional connectivity in generalized anxiety disorder
    • PID: 24254806
    • Andreescu C, Sheu LK, Tudorascu D, Walker S, Aizenstein H. The ages of anxiety—differences across the lifespan in the default mode network functional connectivity in generalized anxiety disorder. Int J Geriatr Psychiatry. 2014;29(7):704–12.
    • (2014) Int J Geriatr Psychiatry , vol.29 , Issue.7 , pp. 704-712
    • Andreescu, C.1    Sheu, L.K.2    Tudorascu, D.3    Walker, S.4    Aizenstein, H.5
  • 25
    • 34848830418 scopus 로고    scopus 로고
    • Inhibitory control and symptom severity in late life generalized anxiety disorder
    • PID: 17662240
    • Price RB, Mohlman J. Inhibitory control and symptom severity in late life generalized anxiety disorder. Behav Res Ther. 2007;45(11):2628–39.
    • (2007) Behav Res Ther , vol.45 , Issue.11 , pp. 2628-2639
    • Price, R.B.1    Mohlman, J.2
  • 26
    • 84884353354 scopus 로고    scopus 로고
    • Attentional bias in older adults: effects of generalized anxiety disorder and cognitive behavior therapy
    • PID: 23916715
    • Mohlman J, Price RB, Vietri J. Attentional bias in older adults: effects of generalized anxiety disorder and cognitive behavior therapy. J Anxiety Disord. 2013;27(6):585–91.
    • (2013) J Anxiety Disord , vol.27 , Issue.6 , pp. 585-591
    • Mohlman, J.1    Price, R.B.2    Vietri, J.3
  • 27
    • 84929451741 scopus 로고    scopus 로고
    • Anxiety disorders
    • Coffey CE, Cummings JL, (eds), American Psychiatric Publishing, Inc, Washington DC
    • Lenze EJ, Wetherell JL, Andreescu C. Anxiety disorders. In: Coffey CE, Cummings JL, editors. Textbook of geriatric neuropsychiatry. 3rd ed. Washington DC: American Psychiatric Publishing, Inc; 2011.
    • (2011) Textbook of geriatric neuropsychiatry
    • Lenze, E.J.1    Wetherell, J.L.2    Andreescu, C.3
  • 28
    • 0018950895 scopus 로고
    • The relationship of age, anxiety, and serum immunoglobulins with crystallized and fluid intelligence
    • COI: 1:STN:280:DyaL3M%2FitF2muw%3D%3D, PID: 7417627
    • Cohen D, Eisdorfer C, Vitaliano PP, Bloom V. The relationship of age, anxiety, and serum immunoglobulins with crystallized and fluid intelligence. Biol Psychiatry. 1980;15(5):699–709.
    • (1980) Biol Psychiatry , vol.15 , Issue.5 , pp. 699-709
    • Cohen, D.1    Eisdorfer, C.2    Vitaliano, P.P.3    Bloom, V.4
  • 29
    • 0027418133 scopus 로고
    • Aging, emotional states, and memory
    • COI: 1:STN:280:DyaK3s7msleksQ%3D%3D, PID: 8434658
    • Deptula D, Singh R, Pomara N. Aging, emotional states, and memory. Am J Psychiatry. 1993;150(3):429–34.
    • (1993) Am J Psychiatry , vol.150 , Issue.3 , pp. 429-434
    • Deptula, D.1    Singh, R.2    Pomara, N.3
  • 30
    • 0037398794 scopus 로고    scopus 로고
    • Divided attention in older but not younger adults is impaired by anxiety
    • PID: 12623724
    • Hogan MJ. Divided attention in older but not younger adults is impaired by anxiety. Exp Aging Res. 2003;29(2):111–36.
    • (2003) Exp Aging Res , vol.29 , Issue.2 , pp. 111-136
    • Hogan, M.J.1
  • 31
    • 35248824227 scopus 로고    scopus 로고
    • Cognitive impairment in late-life generalized anxiety disorder
    • PID: 17426260
    • Mantella RC, Butters MA, Dew MA, et al. Cognitive impairment in late-life generalized anxiety disorder. Am J Geriatr Psychiatry. 2007;15(8):673–9.
    • (2007) Am J Geriatr Psychiatry , vol.15 , Issue.8 , pp. 673-679
    • Mantella, R.C.1    Butters, M.A.2    Dew, M.A.3
  • 32
    • 35248866365 scopus 로고    scopus 로고
    • Cognitive errors, symptom severity, and response to cognitive behavior therapy in older adults with generalized anxiety disorder
    • PID: 17670997
    • Caudle DD, Senior AC, Wetherell JL, et al. Cognitive errors, symptom severity, and response to cognitive behavior therapy in older adults with generalized anxiety disorder. Am J Geriatr Psychiatry. 2007;15(8):680–9.
    • (2007) Am J Geriatr Psychiatry , vol.15 , Issue.8 , pp. 680-689
    • Caudle, D.D.1    Senior, A.C.2    Wetherell, J.L.3
  • 33
    • 0037174346 scopus 로고    scopus 로고
    • Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study
    • PID: 12243634
    • Lyketsos CG, Lopez O, Jones B, Fitzpatrick AL, Breitner J, DeKosky S. Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study. JAMA. 2002;288(12):1475–83.
    • (2002) JAMA , vol.288 , Issue.12 , pp. 1475-1483
    • Lyketsos, C.G.1    Lopez, O.2    Jones, B.3    Fitzpatrick, A.L.4    Breitner, J.5    DeKosky, S.6
  • 34
    • 53849148954 scopus 로고    scopus 로고
    • Prevalence of neuropsychiatric symptoms in mild cognitive impairment and normal cognitive aging: population-based study
    • PID: 18838636
    • Geda YE, Roberts RO, Knopman DS, et al. Prevalence of neuropsychiatric symptoms in mild cognitive impairment and normal cognitive aging: population-based study. Arch Gen Psychiatry. 2008;65(10):1193–8.
    • (2008) Arch Gen Psychiatry , vol.65 , Issue.10 , pp. 1193-1198
    • Geda, Y.E.1    Roberts, R.O.2    Knopman, D.S.3
  • 35
    • 84898896096 scopus 로고    scopus 로고
    • Old worries and new anxieties: behavioral symptoms and mild cognitive impairment in a population study
    • PID: 23759435
    • Andreescu C, Teverovsky E, Fu B, Hughes TF, Chang CC, Ganguli M. Old worries and new anxieties: behavioral symptoms and mild cognitive impairment in a population study. Am J Geriatr Psychiatry. 2014;22(3):274–84.
    • (2014) Am J Geriatr Psychiatry , vol.22 , Issue.3 , pp. 274-284
    • Andreescu, C.1    Teverovsky, E.2    Fu, B.3    Hughes, T.F.4    Chang, C.C.5    Ganguli, M.6
  • 36
    • 34248185078 scopus 로고    scopus 로고
    • Predictors of progression from mild cognitive impairment to Alzheimer disease
    • COI: 1:STN:280:DC%2BD2s3nsFyhsw%3D%3D, PID: 17485646
    • Palmer K, Berger AK, Monastero R, Winblad B, Backman L, Fratiglioni L. Predictors of progression from mild cognitive impairment to Alzheimer disease. Neurology. 2007;68(19):1596–602.
    • (2007) Neurology , vol.68 , Issue.19 , pp. 1596-1602
    • Palmer, K.1    Berger, A.K.2    Monastero, R.3    Winblad, B.4    Backman, L.5    Fratiglioni, L.6
  • 37
    • 77952421790 scopus 로고    scopus 로고
    • Neuropsychiatric predictors of progression from amnestic-mild cognitive impairment to Alzheimer’s disease: the role of depression and apathy
    • PID: 20164594
    • Palmer K, Di Iulio F, Varsi AE, et al. Neuropsychiatric predictors of progression from amnestic-mild cognitive impairment to Alzheimer’s disease: the role of depression and apathy. J Alzheimers Dis. 2010;20(1):175–83.
    • (2010) J Alzheimers Dis , vol.20 , Issue.1 , pp. 175-183
    • Palmer, K.1    Di Iulio, F.2    Varsi, A.E.3
  • 38
    • 84925378753 scopus 로고    scopus 로고
    • Pietrzak RH, Lim YY, Neumeister A, Ames D, Ellis KA, Harrington K, et al. Amyloid-beta, anxiety, and cognitive decline in preclinical Alzheimer disease: a multicenter, prospective cohort study. JAMA Psychiatry. 2015;72:284–291. Very recent study showing that elevated anxiety symptoms moderate the effect of beta-amyloid on cognitive decline in preclinical AD, resulting in more rapid decline in several cognitive domains
    • Pietrzak RH, Lim YY, Neumeister A, Ames D, Ellis KA, Harrington K, et al. Amyloid-beta, anxiety, and cognitive decline in preclinical Alzheimer disease: a multicenter, prospective cohort study. JAMA Psychiatry. 2015;72:284–291. Very recent study showing that elevated anxiety symptoms moderate the effect of beta-amyloid on cognitive decline in preclinical AD, resulting in more rapid decline in several cognitive domains.
  • 39
    • 0025352635 scopus 로고
    • A questionnaire investigation of anxiety and depression in early dementia
    • COI: 1:STN:280:DyaK3c3jsleksw%3D%3D, PID: 2332576
    • Wands K, Merskey H, Hachinski VC, Fisman M, Fox H, Boniferro M. A questionnaire investigation of anxiety and depression in early dementia. J Am Geriatr Soc. 1990;38(5):535–8.
    • (1990) J Am Geriatr Soc , vol.38 , Issue.5 , pp. 535-538
    • Wands, K.1    Merskey, H.2    Hachinski, V.C.3    Fisman, M.4    Fox, H.5    Boniferro, M.6
  • 40
    • 84896894914 scopus 로고    scopus 로고
    • Neural structures, functioning and connectivity in generalized anxiety disorder and interaction with neuroendocrine systems: a systematic review
    • Hilbert K, Lueken U, Beesdo-Baum K. Neural structures, functioning and connectivity in generalized anxiety disorder and interaction with neuroendocrine systems: a systematic review. J Affect Disord. 2014;158C:114–26.
    • (2014) J Affect Disord , vol.158C , pp. 114-126
    • Hilbert, K.1    Lueken, U.2    Beesdo-Baum, K.3
  • 41
    • 0035748224 scopus 로고    scopus 로고
    • Correlation between cortisol level and serotonin uptake in patients with chronic stress and depression
    • COI: 1:STN:280:DC%2BD38jgsFKgtQ%3D%3D, PID: 12467090
    • Tafet GE, Idoyaga-Vargas VP, Abulafia DP, et al. Correlation between cortisol level and serotonin uptake in patients with chronic stress and depression. Cogn Affect Behav Neurosci. 2001;1(4):388–93.
    • (2001) Cogn Affect Behav Neurosci , vol.1 , Issue.4 , pp. 388-393
    • Tafet, G.E.1    Idoyaga-Vargas, V.P.2    Abulafia, D.P.3
  • 42
    • 84875220015 scopus 로고    scopus 로고
    • Decreased hypothalamus volumes in generalized anxiety disorder but not in panic disorder
    • PID: 23084182
    • Terlevic R, Isola M, Ragogna M, et al. Decreased hypothalamus volumes in generalized anxiety disorder but not in panic disorder. J Affect Disord. 2013;146(3):390–4.
    • (2013) J Affect Disord , vol.146 , Issue.3 , pp. 390-394
    • Terlevic, R.1    Isola, M.2    Ragogna, M.3
  • 43
    • 77952888119 scopus 로고    scopus 로고
    • Basal hypothalamic pituitary adrenal axis activity and hippocampal volumes: the SMART-Medea study
    • PID: 20299006
    • Knoops AJ, Gerritsen L, van der Graaf Y, Mali WP, Geerlings MI. Basal hypothalamic pituitary adrenal axis activity and hippocampal volumes: the SMART-Medea study. Biol Psychiatry. 2010;67(12):1191–8.
    • (2010) Biol Psychiatry , vol.67 , Issue.12 , pp. 1191-1198
    • Knoops, A.J.1    Gerritsen, L.2    van der Graaf, Y.3    Mali, W.P.4    Geerlings, M.I.5
  • 44
    • 67651051857 scopus 로고    scopus 로고
    • The brain and the stress axis: the neural correlates of cortisol regulation in response to stress
    • COI: 1:CAS:528:DC%2BC2MXnt1emtLY%3D, PID: 19500680
    • Dedovic K, Duchesne A, Andrews J, Engert V, Pruessner JC. The brain and the stress axis: the neural correlates of cortisol regulation in response to stress. Neuroimage. 2009;47(3):864–71.
    • (2009) Neuroimage , vol.47 , Issue.3 , pp. 864-871
    • Dedovic, K.1    Duchesne, A.2    Andrews, J.3    Engert, V.4    Pruessner, J.C.5
  • 45
    • 33646452139 scopus 로고    scopus 로고
    • Amygdala and ventromedial prefrontal cortex are inversely coupled during regulation of negative affect and predict the diurnal pattern of cortisol secretion among older adults
    • COI: 1:CAS:528:DC%2BD28XkslSgsbo%3D, PID: 16624961
    • Urry HL, van Reekum CM, Johnstone T, et al. Amygdala and ventromedial prefrontal cortex are inversely coupled during regulation of negative affect and predict the diurnal pattern of cortisol secretion among older adults. J Neurosci. 2006;26(16):4415–25.
    • (2006) J Neurosci , vol.26 , Issue.16 , pp. 4415-4425
    • Urry, H.L.1    van Reekum, C.M.2    Johnstone, T.3
  • 46
    • 61749097535 scopus 로고    scopus 로고
    • Bringing the bedside to the bench, and then to the community: a prospectus for intervention research in late-life anxiety disorders
    • PID: 18613267
    • Lenze EJ, Wetherell JL. Bringing the bedside to the bench, and then to the community: a prospectus for intervention research in late-life anxiety disorders. Int J Geriatr Psychiatry. 2009;24(1):1–14.
    • (2009) Int J Geriatr Psychiatry , vol.24 , Issue.1
    • Lenze, E.J.1    Wetherell, J.L.2
  • 47
    • 46249123424 scopus 로고    scopus 로고
    • Salivary cortisol is associated with diagnosis and severity of late-life generalized anxiety disorder
    • COI: 1:CAS:528:DC%2BD1cXosVyjtro%3D, PID: 18407426
    • Mantella RC, Butters MA, Amico JA, et al. Salivary cortisol is associated with diagnosis and severity of late-life generalized anxiety disorder. Psychoneuroendocrinology. 2008;33(6):773–81.
    • (2008) Psychoneuroendocrinology , vol.33 , Issue.6 , pp. 773-781
    • Mantella, R.C.1    Butters, M.A.2    Amico, J.A.3
  • 48
    • 84872845535 scopus 로고    scopus 로고
    • Anxiety disorders and salivary cortisol levels in older adults: a population-based study
    • COI: 1:CAS:528:DC%2BC3sXhvFSnsL0%3D, PID: 22776419
    • Hek K, Direk N, Newson RS, et al. Anxiety disorders and salivary cortisol levels in older adults: a population-based study. Psychoneuroendocrinology. 2013;38(2):300–5.
    • (2013) Psychoneuroendocrinology , vol.38 , Issue.2 , pp. 300-305
    • Hek, K.1    Direk, N.2    Newson, R.S.3
  • 49
    • 79955469074 scopus 로고    scopus 로고
    • Elevated cortisol in older adults with generalized anxiety disorder is reduced by treatment: a placebo-controlled evaluation of escitalopram
    • PID: 20808146
    • Lenze EJ, Mantella RC, Shi P, et al. Elevated cortisol in older adults with generalized anxiety disorder is reduced by treatment: a placebo-controlled evaluation of escitalopram. Am J Geriatr Psychiatry. 2011;19(5):482–90.
    • (2011) Am J Geriatr Psychiatry , vol.19 , Issue.5 , pp. 482-490
    • Lenze, E.J.1    Mantella, R.C.2    Shi, P.3
  • 50
    • 21244459240 scopus 로고    scopus 로고
    • Regulation of hypothalamic-pituitary-adrenal activity in response to cognitive therapy in patients with generalized anxiety disorder
    • PID: 15913006
    • Tafet GE, Feder DJ, Abulafia DP, Roffman SS. Regulation of hypothalamic-pituitary-adrenal activity in response to cognitive therapy in patients with generalized anxiety disorder. Cogn Affect Behav Neurosci. 2005;5(1):37–40.
    • (2005) Cogn Affect Behav Neurosci , vol.5 , Issue.1 , pp. 37-40
    • Tafet, G.E.1    Feder, D.J.2    Abulafia, D.P.3    Roffman, S.S.4
  • 51
    • 34547496875 scopus 로고    scopus 로고
    • Acute stress increases interstitial fluid amyloid-beta via corticotropin-releasing factor and neuronal activity
    • COI: 1:CAS:528:DC%2BD2sXnt1Oktbs%3D, PID: 17551018
    • Kang JE, Cirrito JR, Dong H, Csernansky JG, Holtzman DM. Acute stress increases interstitial fluid amyloid-beta via corticotropin-releasing factor and neuronal activity. Proc Natl Acad Sci U S A. 2007;104(25):10673–8.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , Issue.25 , pp. 10673-10678
    • Kang, J.E.1    Cirrito, J.R.2    Dong, H.3    Csernansky, J.G.4    Holtzman, D.M.5
  • 52
    • 33748253471 scopus 로고    scopus 로고
    • Glucocorticoids increase amyloid-beta and tau pathology in a mouse model of Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BD28Xpt1aqu7w%3D, PID: 16943563
    • Green KN, Billings LM, Roozendaal B, McGaugh JL, LaFerla FM. Glucocorticoids increase amyloid-beta and tau pathology in a mouse model of Alzheimer’s disease. J Neurosci. 2006;26(35):9047–56.
    • (2006) J Neurosci , vol.26 , Issue.35 , pp. 9047-9056
    • Green, K.N.1    Billings, L.M.2    Roozendaal, B.3    McGaugh, J.L.4    LaFerla, F.M.5
  • 53
    • 33846316003 scopus 로고    scopus 로고
    • Plasma cortisol and progression of dementia in subjects with Alzheimer-type dementia
    • PID: 17151169
    • Csernansky JG, Dong H, Fagan AM, et al. Plasma cortisol and progression of dementia in subjects with Alzheimer-type dementia. Am J Psychiatry. 2006;163(12):2164–9.
    • (2006) Am J Psychiatry , vol.163 , Issue.12 , pp. 2164-2169
    • Csernansky, J.G.1    Dong, H.2    Fagan, A.M.3
  • 54
    • 84992218835 scopus 로고    scopus 로고
    • Psychopharmacology
    • Thakur M, Blazer DG, Steffens DC, (eds), American Psychiatric Publishing, Inc, Washington DC
    • Mulsant BHP. Psychopharmacology. In: Thakur M, Blazer DG, Steffens DC, editors. Clinical manual of geriatric psychiatry. Washington DC: American Psychiatric Publishing, Inc; 2014.
    • (2014) Clinical manual of geriatric psychiatry
    • Mulsant, B.H.P.1
  • 55
    • 57749191241 scopus 로고    scopus 로고
    • The critical role of clinical pharmacology in geriatric psychopharmacology
    • PID: 19037202
    • Pollock B, Forsyth C, Bies R. The critical role of clinical pharmacology in geriatric psychopharmacology. Clin Pharmacol Ther. 2009;85(1):89–93.
    • (2009) Clin Pharmacol Ther , vol.85 , Issue.1 , pp. 89-93
    • Pollock, B.1    Forsyth, C.2    Bies, R.3
  • 56
    • 84899839975 scopus 로고    scopus 로고
    • Evidence-based pharmacological treatment of anxiety disorders, post-traumatic stress disorder and obsessive-compulsive disorder: a revision of the 2005 guidelines from the British Association for Psychopharmacology
    • PID: 24713617, Recent consensus paper outlining guidelines for treatment of anxiety disorders
    • Baldwin DS, Anderson IM, Nutt DJ, et al. Evidence-based pharmacological treatment of anxiety disorders, post-traumatic stress disorder and obsessive-compulsive disorder: a revision of the 2005 guidelines from the British Association for Psychopharmacology. J Psychopharmacol. 2014;28(5):403–39. Recent consensus paper outlining guidelines for treatment of anxiety disorders.
    • (2014) J Psychopharmacol , vol.28 , Issue.5 , pp. 403-439
    • Baldwin, D.S.1    Anderson, I.M.2    Nutt, D.J.3
  • 57
    • 33644881625 scopus 로고    scopus 로고
    • A randomized, controlled trial of the effectiveness of cognitive-behavioral therapy and sertraline versus a waitlist control group for anxiety disorders in older adults
    • PID: 16505130
    • Schuurmans J, Comijs H, Emmelkamp PM, et al. A randomized, controlled trial of the effectiveness of cognitive-behavioral therapy and sertraline versus a waitlist control group for anxiety disorders in older adults. Am J Geriatr Psychiatry. 2006;14(3):255–63.
    • (2006) Am J Geriatr Psychiatry , vol.14 , Issue.3 , pp. 255-263
    • Schuurmans, J.1    Comijs, H.2    Emmelkamp, P.M.3
  • 58
    • 11844275258 scopus 로고    scopus 로고
    • Efficacy and tolerability of citalopram in the treatment of late-life anxiety disorders: results from an 8-week randomized, placebo-controlled trial
    • PID: 15625213
    • Lenze EJ, Mulsant BH, Shear MK, et al. Efficacy and tolerability of citalopram in the treatment of late-life anxiety disorders: results from an 8-week randomized, placebo-controlled trial. Am J Psychiatry. 2005;162(1):146–50.
    • (2005) Am J Psychiatry , vol.162 , Issue.1 , pp. 146-150
    • Lenze, E.J.1    Mulsant, B.H.2    Shear, M.K.3
  • 59
    • 77949966633 scopus 로고    scopus 로고
    • Randomized, single-blind, trial of sertraline and buspirone for treatment of elderly patients with generalized anxiety disorder
    • COI: 1:CAS:528:DC%2BC3cXmtlShtLs%3D, PID: 20132529
    • Mokhber N, Azarpazhooh MR, Khajehdaluee M, Velayati A, Hopwood M. Randomized, single-blind, trial of sertraline and buspirone for treatment of elderly patients with generalized anxiety disorder. Psychiatry Clin Neurosci. 2010;64(2):128–33.
    • (2010) Psychiatry Clin Neurosci , vol.64 , Issue.2 , pp. 128-133
    • Mokhber, N.1    Azarpazhooh, M.R.2    Khajehdaluee, M.3    Velayati, A.4    Hopwood, M.5
  • 60
    • 0036143672 scopus 로고    scopus 로고
    • Venlafaxine ER as a treatment for generalized anxiety disorder in older adults: pooled analysis of five randomized placebo-controlled clinical trials
    • PID: 12028242
    • Katz IR, Reynolds 3rd CF, Alexopoulos GS, Hackett D. Venlafaxine ER as a treatment for generalized anxiety disorder in older adults: pooled analysis of five randomized placebo-controlled clinical trials. J Am Geriatr Soc. 2002;50(1):18–25.
    • (2002) J Am Geriatr Soc , vol.50 , Issue.1 , pp. 18-25
    • Katz, I.R.1    Reynolds, C.F.2    Alexopoulos, G.S.3    Hackett, D.4
  • 61
    • 51049108533 scopus 로고    scopus 로고
    • Efficacy and tolerability of duloxetine in elderly patients with generalized anxiety disorder: a pooled analysis of four randomized, double-blind, placebo-controlled studies
    • COI: 1:CAS:528:DC%2BD1cXhtFSlurzJ, PID: 18478624
    • Davidson J, Allgulander C, Pollack MH, et al. Efficacy and tolerability of duloxetine in elderly patients with generalized anxiety disorder: a pooled analysis of four randomized, double-blind, placebo-controlled studies. Hum Psychopharmacol. 2008;23(6):519–26.
    • (2008) Hum Psychopharmacol , vol.23 , Issue.6 , pp. 519-526
    • Davidson, J.1    Allgulander, C.2    Pollack, M.H.3
  • 62
    • 0029553184 scopus 로고
    • Double-blind comparison of paroxetine and nortriptyline on the postural stability of late-life depressed patients
    • COI: 1:CAS:528:DyaK28XitlKrsbk%3D, PID: 8851637
    • Laghrissi-Thode F, Pollock BG, Miller MC, Mulsant BH, Altieri L, Finkel MS. Double-blind comparison of paroxetine and nortriptyline on the postural stability of late-life depressed patients. Psychopharmacol Bull. 1995;31(4):659–63.
    • (1995) Psychopharmacol Bull , vol.31 , Issue.4 , pp. 659-663
    • Laghrissi-Thode, F.1    Pollock, B.G.2    Miller, M.C.3    Mulsant, B.H.4    Altieri, L.5    Finkel, M.S.6
  • 63
    • 33747887675 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitors and risk of upper GI bleeding: confusion or confounding?
    • COI: 1:CAS:528:DC%2BD28Xptlyrs7k%3D, PID: 16945603
    • Yuan Y, Tsoi K, Hunt RH. Selective serotonin reuptake inhibitors and risk of upper GI bleeding: confusion or confounding? Am J Med. 2006;119(9):719–27.
    • (2006) Am J Med , vol.119 , Issue.9 , pp. 719-727
    • Yuan, Y.1    Tsoi, K.2    Hunt, R.H.3
  • 64
    • 34347220867 scopus 로고    scopus 로고
    • Use of antidepressants and rates of hip bone loss in older women: the study of osteoporotic fractures
    • PID: 17592096
    • Diem SJ, Blackwell TL, Stone KL, et al. Use of antidepressants and rates of hip bone loss in older women: the study of osteoporotic fractures. Arch Intern Med. 2007;167(12):1240–5.
    • (2007) Arch Intern Med , vol.167 , Issue.12 , pp. 1240-1245
    • Diem, S.J.1    Blackwell, T.L.2    Stone, K.L.3
  • 65
    • 10744232653 scopus 로고    scopus 로고
    • Paroxetine-induced hyponatremia in older adults: a 12-week prospective study
    • COI: 1:CAS:528:DC%2BD2cXhvVersLc%3D, PID: 14769630
    • Fabian TJ, Amico JA, Kroboth PD, et al. Paroxetine-induced hyponatremia in older adults: a 12-week prospective study. Arch Intern Med. 2004;164(3):327–32.
    • (2004) Arch Intern Med , vol.164 , Issue.3 , pp. 327-332
    • Fabian, T.J.1    Amico, J.A.2    Kroboth, P.D.3
  • 66
    • 77955441417 scopus 로고    scopus 로고
    • Mirtazapine in generalized social anxiety disorder: a randomized, double-blind, placebo-controlled study
    • PID: 20715300
    • Schutters SI, Van Megen HJ, Van Veen JF, Denys DA, Westenberg HG. Mirtazapine in generalized social anxiety disorder: a randomized, double-blind, placebo-controlled study. Int Clin Psychopharmacol. 2010;25(5):302–4.
    • (2010) Int Clin Psychopharmacol , vol.25 , Issue.5 , pp. 302-304
    • Schutters, S.I.1    Van Megen, H.J.2    Van Veen, J.F.3    Denys, D.A.4    Westenberg, H.G.5
  • 67
    • 39749161551 scopus 로고    scopus 로고
    • Use of benzodiazepines and selective serotonin reuptake inhibitors in middle-aged and older adults with anxiety disorders: a longitudinal and prospective study
    • PID: 18165458
    • Benitez CI, Smith K, Vasile RG, Rende R, Edelen MO, Keller MB. Use of benzodiazepines and selective serotonin reuptake inhibitors in middle-aged and older adults with anxiety disorders: a longitudinal and prospective study. Am J Geriatr Psychiatry. 2008;16(1):5–13.
    • (2008) Am J Geriatr Psychiatry , vol.16 , Issue.1 , pp. 5-13
    • Benitez, C.I.1    Smith, K.2    Vasile, R.G.3    Rende, R.4    Edelen, M.O.5    Keller, M.B.6
  • 68
    • 20544445759 scopus 로고    scopus 로고
    • Psychotropic medications and risk for falls among community-dwelling frail older people: an observational study
    • PID: 15972615
    • Landi F, Onder G, Cesari M, Barillaro C, Russo A, Bernabei R. Psychotropic medications and risk for falls among community-dwelling frail older people: an observational study. J Gerontol A Biol Sci Med Sci. 2005;60(5):622–6.
    • (2005) J Gerontol A Biol Sci Med Sci , vol.60 , Issue.5 , pp. 622-626
    • Landi, F.1    Onder, G.2    Cesari, M.3    Barillaro, C.4    Russo, A.5    Bernabei, R.6
  • 69
    • 33645064864 scopus 로고    scopus 로고
    • Benzodiazepine use and physical disability in community-dwelling older adults
    • PID: 16460372
    • Gray SL, LaCroix AZ, Hanlon JT, et al. Benzodiazepine use and physical disability in community-dwelling older adults. J Am Geriatr Soc. 2006;54(2):224–30.
    • (2006) J Am Geriatr Soc , vol.54 , Issue.2 , pp. 224-230
    • Gray, S.L.1    LaCroix, A.Z.2    Hanlon, J.T.3
  • 70
    • 0036107859 scopus 로고    scopus 로고
    • Long-term benzodiazepine use and cognitive decline in the elderly: the Epidemiology of Vascular Aging Study
    • COI: 1:CAS:528:DC%2BD38XksFCkurc%3D, PID: 12006899
    • Paterniti S, Dufouil C, Alperovitch A. Long-term benzodiazepine use and cognitive decline in the elderly: the Epidemiology of Vascular Aging Study. J Clin Psychopharmacol. 2002;22(3):285–93.
    • (2002) J Clin Psychopharmacol , vol.22 , Issue.3 , pp. 285-293
    • Paterniti, S.1    Dufouil, C.2    Alperovitch, A.3
  • 71
    • 62649158905 scopus 로고    scopus 로고
    • Benzodiazepine and antidepressant use in elderly patients with anxiety disorders: a survey of 796 outpatients in Japan
    • PID: 19010641
    • Uchida H, Suzuki T, Mamo DC, et al. Benzodiazepine and antidepressant use in elderly patients with anxiety disorders: a survey of 796 outpatients in Japan. J Anxiety Disord. 2009;23(4):477–81.
    • (2009) J Anxiety Disord , vol.23 , Issue.4 , pp. 477-481
    • Uchida, H.1    Suzuki, T.2    Mamo, D.C.3
  • 72
    • 55949104118 scopus 로고    scopus 로고
    • Efficacy and safety of pregabalin in elderly people with generalised anxiety disorder
    • PID: 18978320
    • Montgomery S, Chatamra K, Pauer L, Whalen E, Baldinetti F. Efficacy and safety of pregabalin in elderly people with generalised anxiety disorder. Br J Psychiatry. 2008;193(5):389–94.
    • (2008) Br J Psychiatry , vol.193 , Issue.5 , pp. 389-394
    • Montgomery, S.1    Chatamra, K.2    Pauer, L.3    Whalen, E.4    Baldinetti, F.5
  • 73
    • 84898056648 scopus 로고    scopus 로고
    • Pregabalin long-term treatment and assessment of discontinuation in patients with generalized anxiety disorder
    • COI: 1:CAS:528:DC%2BC2cXkvF2htLY%3D, PID: 24351233
    • Kasper S, Iglesias-Garcia C, Schweizer E, et al. Pregabalin long-term treatment and assessment of discontinuation in patients with generalized anxiety disorder. Int J Neuropsychopharmacol. 2014;17(5):685–95.
    • (2014) Int J Neuropsychopharmacol , vol.17 , Issue.5 , pp. 685-695
    • Kasper, S.1    Iglesias-Garcia, C.2    Schweizer, E.3
  • 74
    • 84923273463 scopus 로고    scopus 로고
    • A literature review of quetiapine for generalized anxiety disorder
    • COI: 1:CAS:528:DC%2BC2MXivVejt7c%3D, PID: 25689246
    • Kreys TJ, Phan SV. A literature review of quetiapine for generalized anxiety disorder. Pharmacotherapy. 2015;35(2):175–88.
    • (2015) Pharmacotherapy , vol.35 , Issue.2 , pp. 175-188
    • Kreys, T.J.1    Phan, S.V.2
  • 75
    • 84877580124 scopus 로고    scopus 로고
    • Double-blind, randomized study of extended release quetiapine fumarate (quetiapine XR) monotherapy in older patients with generalized anxiety disorder
    • PID: 23070803
    • Mezhebovsky I, Magi K, She F, Datto C, Eriksson H. Double-blind, randomized study of extended release quetiapine fumarate (quetiapine XR) monotherapy in older patients with generalized anxiety disorder. Int J Geriatr Psychiatry. 2013;28(6):615–25.
    • (2013) Int J Geriatr Psychiatry , vol.28 , Issue.6 , pp. 615-625
    • Mezhebovsky, I.1    Magi, K.2    She, F.3    Datto, C.4    Eriksson, H.5
  • 77
    • 31644437978 scopus 로고    scopus 로고
    • New possibilities of treatment for panic attacks in elderly patients: escitalopram versus citalopram
    • COI: 1:CAS:528:DC%2BD28XhsFGhtr8%3D, PID: 16415709
    • Rampello L, Alvano A, Raffaele R, Malaguarnera M, Vecchio I. New possibilities of treatment for panic attacks in elderly patients: escitalopram versus citalopram. J Clin Psychopharmacol. 2006;26(1):67–70.
    • (2006) J Clin Psychopharmacol , vol.26 , Issue.1 , pp. 67-70
    • Rampello, L.1    Alvano, A.2    Raffaele, R.3    Malaguarnera, M.4    Vecchio, I.5
  • 78
    • 10744226550 scopus 로고    scopus 로고
    • Efficacy of sertraline for panic disorder in older adults: a preliminary open-label trial
    • PID: 15010352
    • Sheikh JI, Lauderdale SA, Cassidy EL. Efficacy of sertraline for panic disorder in older adults: a preliminary open-label trial. Am J Geriatr Psychiatry. 2004;12(2):230.
    • (2004) Am J Geriatr Psychiatry , vol.12 , Issue.2 , pp. 230
    • Sheikh, J.I.1    Lauderdale, S.A.2    Cassidy, E.L.3
  • 79
    • 35248873533 scopus 로고    scopus 로고
    • Treatment of anxiety disorders in older adults: a meta-analytic comparison of behavioral and pharmacological interventions
    • PID: 17670995
    • Pinquart M, Duberstein PR. Treatment of anxiety disorders in older adults: a meta-analytic comparison of behavioral and pharmacological interventions. Am J Geriatr Psychiatry. 2007;15(8):639–51.
    • (2007) Am J Geriatr Psychiatry , vol.15 , Issue.8 , pp. 639-651
    • Pinquart, M.1    Duberstein, P.R.2
  • 80
    • 44849141238 scopus 로고    scopus 로고
    • Cognitive-behavioral therapy for adult anxiety disorders: a meta-analysis of randomized placebo-controlled trials
    • PID: 18363421
    • Hofmann SG, Smits JA. Cognitive-behavioral therapy for adult anxiety disorders: a meta-analysis of randomized placebo-controlled trials. J Clin Psychiatry. 2008;69(4):621–32.
    • (2008) J Clin Psychiatry , vol.69 , Issue.4 , pp. 621-632
    • Hofmann, S.G.1    Smits, J.A.2
  • 81
    • 0344837808 scopus 로고    scopus 로고
    • Cognitive-behavioral treatment of late-life generalized anxiety disorder
    • PID: 12699025
    • Stanley MA, Beck JG, Novy DM, et al. Cognitive-behavioral treatment of late-life generalized anxiety disorder. J Consult Clin Psychol. 2003;71(2):309–19.
    • (2003) J Consult Clin Psychol , vol.71 , Issue.2 , pp. 309-319
    • Stanley, M.A.1    Beck, J.G.2    Novy, D.M.3
  • 82
    • 0037304738 scopus 로고    scopus 로고
    • Treatment of generalized anxiety disorder in older adults
    • PID: 12602423
    • Wetherell JL, Gatz M, Craske MG. Treatment of generalized anxiety disorder in older adults. J Consult Clin Psychol. 2003;71(1):31–40.
    • (2003) J Consult Clin Psychol , vol.71 , Issue.1 , pp. 31-40
    • Wetherell, J.L.1    Gatz, M.2    Craske, M.G.3
  • 83
    • 1842764847 scopus 로고    scopus 로고
    • Psychosocial treatment of late-life generalized anxiety disorder: current status and future directions
    • PID: 15081514
    • Mohlman J. Psychosocial treatment of late-life generalized anxiety disorder: current status and future directions. Clin Psychol Rev. 2004;24(2):149–69.
    • (2004) Clin Psychol Rev , vol.24 , Issue.2 , pp. 149-169
    • Mohlman, J.1
  • 86
    • 13444283679 scopus 로고    scopus 로고
    • The role of executive functioning in CBT: a pilot study with anxious older adults
    • PID: 15701356
    • Mohlman J, Gorman JM. The role of executive functioning in CBT: a pilot study with anxious older adults. Behav Res Ther. 2005;43(4):447–65.
    • (2005) Behav Res Ther , vol.43 , Issue.4 , pp. 447-465
    • Mohlman, J.1    Gorman, J.M.2
  • 87
    • 84873268538 scopus 로고    scopus 로고
    • Executive skills in older adults with GAD: relations with clinical variables and CBT outcome
    • PID: 23376600
    • Mohlman J. Executive skills in older adults with GAD: relations with clinical variables and CBT outcome. J Anxiety Disord. 2013;27(1):131–9.
    • (2013) J Anxiety Disord , vol.27 , Issue.1 , pp. 131-139
    • Mohlman, J.1
  • 88
    • 0034769008 scopus 로고    scopus 로고
    • A randomized trial of the effectiveness of cognitive-behavioral therapy and supportive counseling for anxiety symptoms in older adults
    • COI: 1:STN:280:DC%2BD3MrntlSrtA%3D%3D, PID: 11680552
    • Barrowclough C, King P, Colville J, Russell E, Burns A, Tarrier N. A randomized trial of the effectiveness of cognitive-behavioral therapy and supportive counseling for anxiety symptoms in older adults. J Consult Clin Psychol. 2001;69(5):756–62.
    • (2001) J Consult Clin Psychol , vol.69 , Issue.5 , pp. 756-762
    • Barrowclough, C.1    King, P.2    Colville, J.3    Russell, E.4    Burns, A.5    Tarrier, N.6
  • 89
    • 79960161948 scopus 로고    scopus 로고
    • Augmenting antidepressant medication with modular CBT for geriatric generalized anxiety disorder: a pilot study
    • PID: 20872925
    • Wetherell JL, Stoddard JA, White KS, et al. Augmenting antidepressant medication with modular CBT for geriatric generalized anxiety disorder: a pilot study. Int J Geriatr Psychiatry. 2011;26(8):869–75.
    • (2011) Int J Geriatr Psychiatry , vol.26 , Issue.8 , pp. 869-875
    • Wetherell, J.L.1    Stoddard, J.A.2    White, K.S.3
  • 90
    • 84908670460 scopus 로고    scopus 로고
    • Mindfulness-based stress reduction for older adults with worry symptoms and co-occurring cognitive dysfunction
    • PID: 24677282
    • Lenze EJ, Hickman S, Hershey T, et al. Mindfulness-based stress reduction for older adults with worry symptoms and co-occurring cognitive dysfunction. Int J Geriatr Psychiatry. 2014;29(10):991–1000.
    • (2014) Int J Geriatr Psychiatry , vol.29 , Issue.10 , pp. 991-1000
    • Lenze, E.J.1    Hickman, S.2    Hershey, T.3
  • 91
    • 79551500180 scopus 로고    scopus 로고
    • Acceptance and commitment therapy for generalized anxiety disorder in older adults: a preliminary report
    • PID: 21292059
    • Wetherell JL, Afari N, Ayers CR, et al. Acceptance and commitment therapy for generalized anxiety disorder in older adults: a preliminary report. Behav Ther. 2011;42(1):127–34.
    • (2011) Behav Ther , vol.42 , Issue.1 , pp. 127-134
    • Wetherell, J.L.1    Afari, N.2    Ayers, C.R.3
  • 92
    • 20044384075 scopus 로고    scopus 로고
    • Evidence-based pharmacotherapy of Generalized Anxiety Disorder
    • Baldwin DS, Polkinghorn C. Evidence-based pharmacotherapy of Generalized Anxiety Disorder. Int J Neuropsychopharmacol. 2005;8:293–302.
    • (2005) Int J Neuropsychopharmacol , vol.8 , pp. 293-302
    • Baldwin, D.S.1    Polkinghorn, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.