Use of antidepressants and rates of hip bone loss in older women: The study of osteoporotic fractures

Archives of Internal Medicine

Volumn 167, Issue 12, 2007, Pages 1240-1245

  Diem, Susan J ^a   Blackwell, Terri L ^c   Stone, Katie L ^c   Yaffe, Kristine ^d,e   Haney, Elizabeth M ^f   Bliziotes, Michael M ^f   Ensrud, Kristine E ^a,b  

^a UNIVERSITY OF MINNESOTA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^f OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMITRIPTYLINE; AMOXAPINE; BISPHOSPHONIC ACID DERIVATIVE; CALCIUM; CITALOPRAM; DESIPRAMINE; DOXEPIN; ESCITALOPRAM; ESTROGEN; FLUOXETINE; FLUVOXAMINE MALEATE; IMIPRAMINE; NORTRIPTYLINE; PAROXETINE; PROTRIPTYLINE; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; THIAZIDE DIURETIC AGENT; TRICYCLIC ANTIDEPRESSANT AGENT; VITAMIN D;

AGED; ARTICLE; BONE DENSITY; CONTROLLED STUDY; DEPRESSION; FEMALE; GERIATRIC DEPRESSION SCALE; HIP; HUMAN; MAJOR CLINICAL STUDY; OSTEOPOROSIS; PRIORITY JOURNAL;

AGED; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BONE DENSITY; BONE RESORPTION; DENSITOMETRY, X-RAY; DEPRESSION; FEMALE; FOLLOW-UP STUDIES; HIP FRACTURES; HUMANS; INCIDENCE; OSTEOPOROSIS; PROGNOSIS; PROSPECTIVE STUDIES; QUESTIONNAIRES; RISK FACTORS; SEROTONIN UPTAKE INHIBITORS; TIME FACTORS; UNITED STATES;

EID: 34347220867     PISSN: 00039926     EISSN: 15383679     Source Type: Journal    
DOI: 10.1001/archinte.167.12.1240     Document Type: Article

References (33)

1. Trends in antidepressant use. AHRQ News and Numbers, May 16, 2005. Rockville, Md: Agency for Healthcare Research and Quality. http://www.ahrq.gov/ news/nn/nn051605.htm. Accessed February 3, 2006.
2. Harman JS, Crystal S, Walkup J, Olfson M. Trends in elderly patients' office visits for the treatment of depression according to physician specialty: 1985-1999. J Behav Health Serv Res. 2003;30:332-341.
3. Stahl SM. Basic psychopharmacology of antidepressants, I: antidepressants have seven distinct mechanisms of action. J Clin Psychiatry. 1998;59(suppl 4):5-14.
4. Battaglino R, Fu J, Spate U, et al. Serotonin regulates osteoclast differentiation through its transporter. J Bone Miner Res. 2004;19:1420-1431.
5. Bliziotes MM, Eshleman A, Zhang X, Wiren K. Neurotransmitter action in osteoblasts: expression of a functional system for serotonin receptor activation and reuptake. Bone. 2001;29:477-486.
6. Cummings SR, Black DM, Nevitt MC, et al; Study of Osteoporotic Fractures Research Group. Appendicular bone density and age predict hip fracture in women. JAMA. 1990;263:665-668.
7. Vogt MT, Rubin DA, Palermo L, et al. Lumbar spine listhesis in older African American women. Spine J. 2003;3:255-261.
8. Robbins J, Hirsch C, Whitmer R, Cauley J, Harris T. The association of bone mineral density and depression in an older population. J Am Geriatr Soc. 2001;49:732-736.
9. Michelson D, Stratakis C, Hill L, et al. Bone mineral density in women with depression. N Engl J Med. 1996;335:1176-1181.
10. Schweiger U, Weber B, Deuschle M, Heuser I. Lumbar bone mineral density in patients with major depression: evidence of increased bone loss at follow-up. Am J Psychiatry. 2000;157:118-120.
11. Pahor M, Chrischilles EA, Guralnik JM, et al. Drug data coding and analysis in epidemiologic studies. Eur J Epidemiol. 1994;10:405-411.
12. Steiger P, Cummings SR, Black DM, Spencer NE, Genant HK. Age-related decrements in bone mineral density in women over 65. J Bone Miner Res. 1992;7:625-632.
13. Ensrud KE, Palermo L, Black DM, et al. Hip and calcaneal bone loss increase with advancing age: longitudinal results from the study of osteoporotic fractures. J Bone Miner Res. 1995;10:1778-1787.
14. Sheikh JI, Yesavage JA. Geriatric Depression Scale (GDS): recent evidence and development of a shorter version. In: Brink TL, ed. Clinical Gerontology: A Guide to Assessment and Intervention. Binghamton, NY: Haworth Press Inc; 1986: 165-173.
15. Gerety MB, Williams JW Jr, Mulrow CD, et al. Performance of case-finding tools for depression in the nursing home: influence of clinical and functional characteristics and selection of optimal threshold scores. J Am Geriatr Soc. 1994;42:1103-1109.
16. Cummings SR, Block G, McHenry K, et al. Evaluation of two food frequency methods of measuring dietary calcium intake. Am J Epidemiol. 1987;126:796-802.
17. Ensrud KE, Nevitt MC, Yunis C, et al. Correlates of impaired function in older women. J Am Geriatr Soc. 1994;42:481-489.
18. Fitti JE, Kovar MG. The supplement on aging to the 1984 National Health Interview Survey. Vital Health Stat 1. 1987:1-115.
19. Pincus T, Summey JA, Soraci SA, et al. Assessment of patient satisfaction in activities of daily living using a modified Stanford Health Assessment Questionnaire. Arthritis Rheum. 1983;26:1346-1353.
20. Folstein MF, Robins LN, Helzer JE. The Mini-Mental State Examination. Arch Gen Psychiatry. 1983;40:812.
21. Lohman TG, Roche AF, Mavtorell R. Anthropometric Standardization Reference Manual. Champaign, Ill: Human Kinetics Books; 1988:177.
22. Ensrud KE, Walczak TS, Blackwell T, Ensrud ER, Bowman PJ, Stone KL. Anti-epileptic drug use increases rates of bone loss in older women: a prospective study. Neurology. 2004;62:2051-2057.
23. Bliziotes M, Eshleman A, Burt-Pichat B, et al. Serotonin transporter and receptor expression in osteocytic MLO-Y4 cells. Bone. 2006;39:1313-1321. doi:10.1016/j.bone.2006.06.009.
24. Gustafsson BI, Thommesen L, Stunes AK, et al. Serotonin and fluoxetine modulate bone cell function in vitro. J Cell Biochem. 2006;98:139-151.
25. Warden SJ, Robling AG, Sanders MS, Bliziotes MM, Turner CH. Inhibition of the serotonin (5-hydroxytryptamine) transporter reduces bone accrual during growth. Endocrinology. 2005;146:685-693.
26. Haney EM, Chan BKS, Diem SJ, et al; Osteoporotic Fractures in Men Study Group. Association of low bone mineral density with selective serotonin reuptake inhibitor use by older men. Arch Intern Med. 2007;167:1246-1251.
27. Ensrud KE, Blackwell T, Mangione CM, et al. Central nervous system active medications and risk for fractures in older women. Arch Intern Med. 2003;163:949-957.
28. Kinjo M, Setoguchi S, Schneeweiss S, Solomon D. Bone mineral density in subjects using central nervous system-active medications. Am J Med. 2005;118:1414.e7-1414.e12. doi:10.1016/j.amjmed.2005.07.033.
29. Liu B, Anderson G, Mittman N, To T, Axcell T, Shear N. Use of selective serotonin-reupate inhibitors or tricyclic antidepressants and risk of hip fractures in elderly people. Lancet. 1998;351:1303-1307.
30. Hubbard R, Farrington P, Smith C, Smeeth L, Tattersfield A. Exposure to tricyclic and selective serotonin reuptake inhibitor antidepressants and the risk of hip fracture. Am J Epidemiol. 2003;158:77-84.
31. Furlan PM, Ten Have T, Cary M, et al. The role of stress-induced cortisol in the relationship between depression and decreased bone mineral density. Biol Psychiatry. 2005;57:911-917.
32. Kahl KG, Rudolf S, Stoeckelhuber BM, et al. Bone mineral density, markers of bone turnover, and cytokines in young women with borderline personality disorder with and without comorbid major depressive disorder. Am J Psychiatry. 2005;162:168-174.
33. Fitzpatrick LA. Secondary causes of osteoporosis. Mayo Clin Proc. 2002;77:453-468.