GIRK channels modulate opioid-induced motor activity in a cell type- and subunit-dependent manner

Journal of Neuroscience

Volumn 35, Issue 18, 2015, Pages 7131-7142

  Kotecki, Lydia ^a   Hearing, Matthew ^a   McCall, Nora M ^a   de Velasco, Ezequiel Marron Fernandez ^a   Pravetoni, Marco ^a,b   Arora, Devinder ^a   Victoria, Nicole C ^a   Munoz, Michaelanne B ^c   Xia, Zhilian ^a   Slesinger, Paul A ^c,d   Weaver, C David ^e   Wickman, Kevin ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b MINNEAPOLIS MEDICAL RESEARCH FOUNDATION   (United States)

^c SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Conditional knockout; GIRK; Kir3; Morphine; Rostromedial tegmental area; Ventral tegmental area

Indexed keywords

4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR; BACLOFEN; ENHANCED GREEN FLUORESCENT PROTEIN; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL 1; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL 2; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL 3; MORPHINE; NALOXONE; NEOMYCIN; REGULATOR PROTEIN; TRANSCRIPTION FACTOR PITX3; UNCLASSIFIED DRUG; YELLOW FLUORESCENT PROTEIN; KCNJ6 PROTEIN, MOUSE; NARCOTIC ANALGESIC AGENT; PROTEIN SUBUNIT;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN ELECTROPHYSIOLOGY; CEREBELLUM; CONTROLLED STUDY; DNA SEQUENCE; EVOKED RESPONSE; EXPERIMENTAL BEHAVIORAL TEST; GENETIC MANIPULATION; GENOTYPE; HIPPOCAMPUS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MEMBRANE STEADY POTENTIAL; MOTOR ACTIVITY; MOUSE; NERVE CELL INHIBITION; NERVE STIMULATION; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SUBSTANTIA NIGRA PARS RETICULATA; VENTRAL TEGMENTUM; ANIMAL; C57BL MOUSE; DOPAMINERGIC NERVE CELL; DOSE RESPONSE; DRUG EFFECTS; KNOCKOUT MOUSE; PHYSIOLOGY; PROTEIN SUBUNIT;

ANALGESICS, OPIOID; ANIMALS; DOPAMINERGIC NEURONS; DOSE-RESPONSE RELATIONSHIP, DRUG; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; GABAERGIC NEURONS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; PROTEIN SUBUNITS; VENTRAL TEGMENTAL AREA;

EID: 84929377090     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5051-14.2015     Document Type: Article

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