Systemic morphine-induced Fos protein in the rat striatum and nucleus accumbens is regulated by μ opioid receptors in the substantia nigra and ventral tegmental area

Journal of Neuroscience

Volumn 17, Issue 21, 1997, Pages 8596-8612

  Bontempi, Bruno ^b   Sharp, Frank R ^a  

^a SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b NONE

Author keywords

Drug addiction; Fos; Immediate early genes; Morphine; Nucleus accumbens; Parkinson's disease; Rotational behavior; Striatum; Substantia nigra; Ventral tegmental area

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; BICUCULLINE; DIZOCILPINE; DOPAMINE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; GLUTAMIC ACID; MORPHINE; NALOXONAZINE; PROTEIN C FOS; SIGMA OPIATE RECEPTOR;

ADDICTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CIRCLING BEHAVIOR; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINE RELEASE; DOPAMINERGIC NERVE CELL; DRUG DEPENDENCE; FEMALE; GENE EXPRESSION; GLOBUS PALLIDUS; IMMEDIATE EARLY GENE; INTERNEURON; NERVE CELL; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN INDUCTION; RAT; REGULATORY MECHANISM; SUBSTANTIA NIGRA; VENTRAL TEGMENTUM;

EID: 0030730282     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-21-08596.1997     Document Type: Article

References (27)

1. Akil H, Watson SJ, Young E, Lewis ME, Khachaturian H, Walker JM (1984) Endogenous opioids: biology and function. Annu Rev Neurosci 7:223-255.
2. Albin RL, Young AB, Penney JB (1995) The functional anatomy of disorders of the basal ganglia. Trends Neurosci 18:63-64.
3. Alexander GE, Crutcher MD (1990) Functional architecture of basal ganglia circuits: neural substrates of parallel processing. Trends Neurosci 13:266-271.
4. Aronin N, Chase K, Sagar SM, Sharp FR, DiFiglia M (1991) N-methyl-D-aspartate receptor activation in the neostriatum increases c-fos and fos-related antigens selectively in medium-sized neurons. Neuroscience 44:409-420.
5. Bading H, Ginty DD, Greenberg ME (1993) Regulation of gene expression in hippocampal neurons by distinct calcium signalling pathways. Science 260:181-186.
6. Berendse HK, Groenewegen HJ (1991) Restricted cortical termination fields of the midline and intralaminar thalamic nuclei in the rat. Neuroscience 42:73-102.
7. Berendse HK, Galis-de-Graaf Y, Groenewegen HJ (1992) Topographical organization and relationship with ventral striatal compartments of prefrontal corticostriatal projections in the rat. J Comp Neurol 316:314-347.
8. Berretta S, Robertson HA, Graybiel AM (1992) Dopamine and glutamate agonists stimulate neuron-specific expression of Fos-like protein in the striatum. J Neurophysiol 68:767-777.
9. Bhargava HN, Villar VM, Rahmani NH, Larsen KA (1992) Time course of the distribution of morphine in brain regions and spinal cord after intravenous injection to spontaneously hypertensive and normotensive Wistar-Kyoto rats. J Pharmacol Exp Ther 261:1008-1014.
10. Boja JW, Vaughan R, Patel A, Shaya EK, Kuhar MJ (1994) The dopamine transporter. In: Dopamine receptors and transporter: pharmacology, structure and function (Niznik HB, ed), pp 611-644. New York: Dekker M.
11. Bontempi B, Liu J, Massa SS, Sharp FR (1995) Intracerebral injection of morphine into the substantia nigra induces c-fos protein in striatum associated with rotational behavior. Soc Neurosci Abstr 21:1849.
12. Bozarth MA, Wise RA (1984) Anatomically distinct opiate receptor fields mediate reward and physical dependence. Science 224:516-517.
13. Brown LL, Sharp FR (1995) Metabolic mapping of rat striatum: somatotopic organization of sensorimotor activity. Brain Res 686:207-222.
14. Cenci MA, Campbell K, Wictorin K, Bjorklund A (1992) Striatal c-fos induction by cocaine or apomorphine occurs preferentially in output neurons projecting to the substantia nigra in the rat. Eur J Neurosci 4:376-380.
15. Chang SL, Squinto SP, Harlan RE (1988) Morphine activation of c-fos expression in rat brain. Biochem Biophys Res Commun 157:698-704.
16. 1 dopamine receptor activation of multiple transcription factor genes in the rat striatum. J Neurochem 58:1420-1426.
17. Collart MA, Tourkine N, Belin D, Vassalli P, Jeanteur P, Blanchard J-M (1991) c-fos gene transcription in murine macrophages is modulated by a calcium-dependent block to elongation in intron 1. Mol Cell Biol 11:2826-2831.
18. Cooper JR, Bloom FE, Roth RH (1991) The biochemical basis of neuropharmacology, 6th edition. New York: Oxford UP.
19. Cruciani RA, Lutz RA, Munson PJ, Rodbard D (1987) Naloxonazine effects on the interaction of enkephalin analogs with Mu-1, Mu and Delta opioid binding sites in rat brain membranes. J Pharmacol Exp Ther 242:15-20.
20. David V, Cazala P (1994) Differentiation of intracranial morphine self-administration behavior among five brain regions in mice. Pharmacol Biochem Behav 48:625-633.
21. 2 dopaminergic mechanisms. Psychopharmacology 130:85-90.
22. De Togni P, Niman H, Raymond V, Sawchenko P, Verma IM (1988) Detection of Fos protein during osteogenesis by monoclonal antibodies. Mol Cell Biol 8:2251-2256.
23. Devine DP, Wise RA (1994) Self-administration of morphine, DAMGO, and DPDPE into the ventral tegmental area of rats. J Neurosci 14:1978-1984.
24. Devine DP, Leone P, Pocock D, Wise RA (1993) Differential involvement of ventral tegmental Mu, Delta, and Kappa opioid receptors in modulation of basolimbic dopamine release: in vitro microdialysis studies. J Pharmacol Exp Ther 266:1236-1246.
25. Di Chiara G, Imperato A (1988a) Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc Natl Acad Sci USA 85:5274-5278.
26. Di Chiara G, Imperato A (1988b) Opposite effects of Mu and Kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats. J Pharmacol Exp Ther 244:1067-1080.
27. Di Chiara G, North RA (1992) Neurobiology of opiate abuse. Trends Pharmacol Sci 13:185-193.