Poly(amidoamine) dendrimers with carbonic anhydrase inhibitory activity and antiglaucoma action

Journal of Medicinal Chemistry

Volumn 58, Issue 9, 2015, Pages 4039-4045

  Carta, Fabrizio ^a   Osman, Sameh M ^b   Vullo, Daniela ^a   Gullotto, Antonella ^a   Winum, Jean Yves ^c   Alothman, Zeid ^b   Masini, Emanuela ^a   Supuran, Claudiu T ^a,b  

^a UNIVERSITY OF FLORENCE   (Italy)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

^c UNIV MONTPELLIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAZOLAMIDE; ANTIGLAUCOMA AGENT; BENZENESULFONAMIDE DERIVATIVE; CARBONATE DEHYDRATASE; CARBONATE DEHYDRATASE INHIBITOR; DENDRIMER; DORZOLAMIDE; POLYAMIDOAMINE; SULFONAMIDE; BENZENESULFONAMIDE; CA9 PROTEIN, HUMAN; CARBONATE DEHYDRATASE I; CARBONATE DEHYDRATASE II; CARBONATE DEHYDRATASE XII; ISOENZYME; POLYAMINE; TUMOR ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; ENZYME INHIBITION; GLAUCOMA; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; INTRAOCULAR PRESSURE; LONG TERM CARE; MALE; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; RABBIT MODEL; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; HUMAN; METABOLISM; PATHOPHYSIOLOGY; RABBIT; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANIMALS; ANTIGENS, NEOPLASM; CARBONIC ANHYDRASE I; CARBONIC ANHYDRASE II; CARBONIC ANHYDRASES; DENDRIMERS; GLAUCOMA; HUMANS; INTRAOCULAR PRESSURE; ISOENZYMES; MALE; POLYAMINES; RABBITS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

EID: 84929358944     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/acs.jmedchem.5b00383     Document Type: Article

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