-
1
-
-
38649093611
-
Neuroblastoma: biology, prognosis, and treatment
-
Park JR, Eggert A, Caron H: Neuroblastoma: biology, prognosis, and treatment. Pediatr Clin North Am 2008, 55(1):97-120.
-
(2008)
Pediatr Clin North Am
, vol.55
, Issue.1
, pp. 97-120
-
-
Park, J.R.1
Eggert, A.2
Caron, H.3
-
2
-
-
80655127696
-
The MYCN oncogene and differentiation in neuroblastoma
-
Westermark UK, Wilhelm M, Frenzel A, Henriksson MA: The MYCN oncogene and differentiation in neuroblastoma. Semin Cancer Biol 2011, 21(4):256-266.
-
(2011)
Semin Cancer Biol
, vol.21
, Issue.4
, pp. 256-266
-
-
Westermark, U.K.1
Wilhelm, M.2
Frenzel, A.3
Henriksson, M.A.4
-
3
-
-
84893823680
-
Therapeutic targets for neuroblastomas
-
Brodeur GM, Iyer R, Croucher JL, Zhuang T, Higashi M, Kolla V: Therapeutic targets for neuroblastomas. Expert Opin Ther Targets 2014, 18(3):277-92.
-
(2014)
Expert Opin Ther Targets
, vol.18
, Issue.3
, pp. 277-292
-
-
Brodeur, G.M.1
Iyer, R.2
Croucher, J.L.3
Zhuang, T.4
Higashi, M.5
Kolla, V.6
-
4
-
-
0035577854
-
Hedgehog signaling in animal development: paradigms and principles
-
Ingham PW, McMahon AP: Hedgehog signaling in animal development: paradigms and principles. Genes Dev 2001, 15(23):3059-3087.
-
(2001)
Genes Dev
, vol.15
, Issue.23
, pp. 3059-3087
-
-
Ingham, P.W.1
McMahon, A.P.2
-
5
-
-
0033214342
-
Gli proteins and Hedgehog signaling: development and cancer
-
Ruiz I, Altaba A: Gli proteins and Hedgehog signaling: development and cancer. Trends Genet 1999, 15(10):418-425.
-
(1999)
Trends Genet
, vol.15
, Issue.10
, pp. 418-425
-
-
Ruiz, I.1
Altaba, A.2
-
6
-
-
77649337790
-
Hedgehog beyond medulloblastoma and basal cell carcinoma
-
Teglund S, Toftgard R: Hedgehog beyond medulloblastoma and basal cell carcinoma. Biochim Biophys Acta 2010, 1805(2):181-208.
-
(2010)
Biochim Biophys Acta
, vol.1805
, Issue.2
, pp. 181-208
-
-
Teglund, S.1
Toftgard, R.2
-
7
-
-
29744463531
-
Deregulation of the hedgehog signalling pathway: a possible role for the PTCH and SUFU genes in human rhabdomyoma and rhabdomyosarcoma development
-
Tostar U, Malm CJ, Meis-Kindblom JM, Kindblom LG, Toftgard R, Unden AB: Deregulation of the hedgehog signalling pathway: a possible role for the PTCH and SUFU genes in human rhabdomyoma and rhabdomyosarcoma development. J Pathol 2006, 208(1):17-25.
-
(2006)
J Pathol
, vol.208
, Issue.1
, pp. 17-25
-
-
Tostar, U.1
Malm, C.J.2
Meis-Kindblom, J.M.3
Kindblom, L.G.4
Toftgard, R.5
Unden, A.B.6
-
8
-
-
0037447269
-
Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions
-
Williams JA, Guicherit OM, Zaharian BI, Xu Y, Chai L, Wichterle H, Kon C, Gatchalian C, Porter JA, Rubin LL, Wang FY: Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions. Proc Natl Acad Sci U S A 2003, 100(8):4616-4621.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.8
, pp. 4616-4621
-
-
Williams, J.A.1
Guicherit, O.M.2
Zaharian, B.I.3
Xu, Y.4
Chai, L.5
Wichterle, H.6
Kon, C.7
Gatchalian, C.8
Porter, J.A.9
Rubin, L.L.10
Wang, F.Y.11
-
9
-
-
2942533929
-
Hedgehog signalling in colorectal tumour cells: induction of apoptosis with cyclopamine treatment
-
Qualtrough D, Buda A, Gaffield W, Williams AC, Paraskeva C: Hedgehog signalling in colorectal tumour cells: induction of apoptosis with cyclopamine treatment. Int J Cancer 2004, 110(6):831-837.
-
(2004)
Int J Cancer
, vol.110
, Issue.6
, pp. 831-837
-
-
Qualtrough, D.1
Buda, A.2
Gaffield, W.3
Williams, A.C.4
Paraskeva, C.5
-
10
-
-
0036829397
-
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
-
Chen JK, Taipale J, Cooper MK, Beachy PA: Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened. Genes Dev 2002, 16(21):2743-2748.
-
(2002)
Genes Dev
, vol.16
, Issue.21
, pp. 2743-2748
-
-
Chen, J.K.1
Taipale, J.2
Cooper, M.K.3
Beachy, P.A.4
-
11
-
-
84879780888
-
Guggulsterone sensitizes glioblastoma cells to Sonic hedgehog inhibitor SANT-1 induced apoptosis in a Ras/NFkappaB dependent manner
-
Dixit D, Ghildiyal R, Anto NP, Ghosh S, Sharma V, Sen E: Guggulsterone sensitizes glioblastoma cells to Sonic hedgehog inhibitor SANT-1 induced apoptosis in a Ras/NFkappaB dependent manner. Cancer Lett 2013, 336(2):347-358.
-
(2013)
Cancer Lett
, vol.336
, Issue.2
, pp. 347-358
-
-
Dixit, D.1
Ghildiyal, R.2
Anto, N.P.3
Ghosh, S.4
Sharma, V.5
Sen, E.6
-
12
-
-
80052225991
-
Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells
-
Mazumdar T, Devecchio J, Agyeman A, Shi T, Houghton JA: Blocking Hedgehog survival signaling at the level of the GLI genes induces DNA damage and extensive cell death in human colon carcinoma cells. Cancer Res 2011, 71(17):5904-5914.
-
(2011)
Cancer Res
, vol.71
, Issue.17
, pp. 5904-5914
-
-
Mazumdar, T.1
Devecchio, J.2
Agyeman, A.3
Shi, T.4
Houghton, J.A.5
-
13
-
-
84863980527
-
Sonic Hedgehog pathway is essential for neuroblastoma cell proliferation and tumor growth
-
Xu L, Wang X, Wan J, Li T, Gong X, Zhang K, Yi L, Xiang Z, Xu M, Cui H: Sonic Hedgehog pathway is essential for neuroblastoma cell proliferation and tumor growth. Mol Cell Biochem 2012, 364(1-2):235-241.
-
(2012)
Mol Cell Biochem
, vol.364
, Issue.1-2
, pp. 235-241
-
-
Xu, L.1
Wang, X.2
Wan, J.3
Li, T.4
Gong, X.5
Zhang, K.6
Yi, L.7
Xiang, Z.8
Xu, M.9
Cui, H.10
-
14
-
-
70349599606
-
A critical role of Sonic Hedgehog signaling in maintaining the tumorigenicity of neuroblastoma cells
-
Mao L, Xia YP, Zhou YN, Dai RL, Yang X, Duan SJ, Qiao X, Mei YW, Hu B, Cui H: A critical role of Sonic Hedgehog signaling in maintaining the tumorigenicity of neuroblastoma cells. Cancer Sci 2009, 100(10):1848-1855.
-
(2009)
Cancer Sci
, vol.100
, Issue.10
, pp. 1848-1855
-
-
Mao, L.1
Xia, Y.P.2
Zhou, Y.N.3
Dai, R.L.4
Yang, X.5
Duan, S.J.6
Qiao, X.7
Mei, Y.W.8
Hu, B.9
Cui, H.10
-
15
-
-
80051705699
-
Inhibition of the sonic hedgehog pathway by cyplopamine reduces the CD133+/CD15+ cell compartment and the in vitro tumorigenic capability of neuroblastoma cells
-
Schiapparelli P, Shahi MH, Enguita-German M, Johnsen JI, Kogner P, Lazcoz P, Castresana JS: Inhibition of the sonic hedgehog pathway by cyplopamine reduces the CD133+/CD15+ cell compartment and the in vitro tumorigenic capability of neuroblastoma cells. Cancer Lett 2011, 310(2):222-231.
-
(2011)
Cancer Lett
, vol.310
, Issue.2
, pp. 222-231
-
-
Schiapparelli, P.1
Shahi, M.H.2
Enguita-German, M.3
Johnsen, J.I.4
Kogner, P.5
Lazcoz, P.6
Castresana, J.S.7
-
16
-
-
84873082449
-
Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo
-
Wickstrom M, Dyberg C, Shimokawa T, Milosevic J, Baryawno N, Fuskevag OM, Larsson R, Kogner P, Zaphiropoulos PG, Johnsen JI: Targeting the hedgehog signal transduction pathway at the level of GLI inhibits neuroblastoma cell growth in vitro and in vivo. Int J Cancer 2013, 132(7):1516-1524.
-
(2013)
Int J Cancer
, vol.132
, Issue.7
, pp. 1516-1524
-
-
Wickstrom, M.1
Dyberg, C.2
Shimokawa, T.3
Milosevic, J.4
Baryawno, N.5
Fuskevag, O.M.6
Larsson, R.7
Kogner, P.8
Zaphiropoulos, P.G.9
Johnsen, J.I.10
-
17
-
-
84863954409
-
Regulation and function of autophagy during cell survival and cell death
-
Das G, Shravage BV, Baehrecke EH: Regulation and function of autophagy during cell survival and cell death. Cold Spring Harb Perspect Biol 2012, 4(6):1-14.
-
(2012)
Cold Spring Harb Perspect Biol
, vol.4
, Issue.6
, pp. 1-14
-
-
Das, G.1
Shravage, B.V.2
Baehrecke, E.H.3
-
18
-
-
33745713171
-
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
-
Degenhardt K, Mathew R, Beaudoin B, Bray K, Anderson D, Chen G, Mukherjee C, Shi Y, Gelinas C, Fan Y, Nelson DA, Jin S, White E: Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell 2006, 10(1):51-64.
-
(2006)
Cancer Cell
, vol.10
, Issue.1
, pp. 51-64
-
-
Degenhardt, K.1
Mathew, R.2
Beaudoin, B.3
Bray, K.4
Anderson, D.5
Chen, G.6
Mukherjee, C.7
Shi, Y.8
Gelinas, C.9
Fan, Y.10
Nelson, D.A.11
Jin, S.12
White, E.13
-
19
-
-
25444440875
-
The role of autophagy in cancer development and response to therapy
-
Kondo Y, Kanzawa T, Sawaya R, Kondo S: The role of autophagy in cancer development and response to therapy. Nat Rev Cancer 2005, 5(9):726-734.
-
(2005)
Nat Rev Cancer
, vol.5
, Issue.9
, pp. 726-734
-
-
Kondo, Y.1
Kanzawa, T.2
Sawaya, R.3
Kondo, S.4
-
20
-
-
84867294606
-
Regulation of inflammatory response by 3-methyladenine involves the coordinative actions on Akt and glycogen synthase kinase 3beta rather than autophagy
-
Lin YC, Kuo HC, Wang JS, Lin WW: Regulation of inflammatory response by 3-methyladenine involves the coordinative actions on Akt and glycogen synthase kinase 3beta rather than autophagy. J Immunol 2012, 189 (8):4154-4164.
-
(2012)
J Immunol
, vol.189
, Issue.8
, pp. 4154-4164
-
-
Lin, Y.C.1
Kuo, H.C.2
Wang, J.S.3
Lin, W.W.4
-
21
-
-
33947254016
-
Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers
-
Feldmann G, Dhara S, Fendrich V, Bedja D, Beaty R, Mullendore M, Karikari C, Alvarez H, Iacobuzio-Donahue C, Jimeno A, Gabrielson KL, Matsui W, Maitra A: Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers. Cancer Res 2007, 67(5):2187-2196.
-
(2007)
Cancer Res
, vol.67
, Issue.5
, pp. 2187-2196
-
-
Feldmann, G.1
Dhara, S.2
Fendrich, V.3
Bedja, D.4
Beaty, R.5
Mullendore, M.6
Karikari, C.7
Alvarez, H.8
Iacobuzio-Donahue, C.9
Jimeno, A.10
Gabrielson, K.L.11
Matsui, W.12
Maitra, A.13
-
22
-
-
33645065340
-
The MYCN enigma: significance of MYCN expression in neuroblastoma
-
Tang XX, Zhao H, Kung B, Kim DY, Hicks SL, Cohn SL, Cheung NK, Seeger RC, Evans AE, Ikegaki N: The MYCN enigma: significance of MYCN expression in neuroblastoma. Cancer Res 2006, 66(5):2826-2833.
-
(2006)
Cancer Res
, vol.66
, Issue.5
, pp. 2826-2833
-
-
Tang, X.X.1
Zhao, H.2
Kung, B.3
Kim, D.Y.4
Hicks, S.L.5
Cohn, S.L.6
Cheung, N.K.7
Seeger, R.C.8
Evans, A.E.9
Ikegaki, N.10
-
23
-
-
0021261878
-
Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage
-
Brodeur GM, Seeger RC, Schwab M, Varmus HE, Bishop JM: Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage. Science 1984, 224(4653):1121-1124.
-
(1984)
Science
, vol.224
, Issue.4653
, pp. 1121-1124
-
-
Brodeur, G.M.1
Seeger, R.C.2
Schwab, M.3
Varmus, H.E.4
Bishop, J.M.5
-
24
-
-
0034724389
-
Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion
-
Coller HA, Grandori C, Tamayo P, Colbert T, Lander ES, Eisenman RN, Golub TR: Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion. Proc Natl Acad Sci U S A 2000, 97(7):3260-3265.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, Issue.7
, pp. 3260-3265
-
-
Coller, H.A.1
Grandori, C.2
Tamayo, P.3
Colbert, T.4
Lander, E.S.5
Eisenman, R.N.6
Golub, T.R.7
-
25
-
-
0022388606
-
Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas
-
Seeger RC, Brodeur GM, Sather H, Dalton A, Siegel SE, Wong KY, Hammond D: Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. N Engl J Med 1985, 313(18):1111-1116.
-
(1985)
N Engl J Med
, vol.313
, Issue.18
, pp. 1111-1116
-
-
Seeger, R.C.1
Brodeur, G.M.2
Sather, H.3
Dalton, A.4
Siegel, S.E.5
Wong, K.Y.6
Hammond, D.7
-
26
-
-
0035114278
-
Inhibition of N-myc expression and induction of apoptosis by iron chelation in human neuroblastoma cells
-
Fan L, Iyer J, Zhu S, Frick KK, Wada RK, Eskenazi AE, Berg PE, Ikegaki N, Kennett RH, Frantz CN: Inhibition of N-myc expression and induction of apoptosis by iron chelation in human neuroblastoma cells. Cancer Res 2001, 61(3):1073-1079.
-
(2001)
Cancer Res
, vol.61
, Issue.3
, pp. 1073-1079
-
-
Fan, L.1
Iyer, J.2
Zhu, S.3
Frick, K.K.4
Wada, R.K.5
Eskenazi, A.E.6
Berg, P.E.7
Ikegaki, N.8
Kennett, R.H.9
Frantz, C.N.10
-
27
-
-
0033580238
-
MycN sensitizes neuroblastoma cells for drug-induced apoptosis
-
Fulda S, Lutz W, Schwab M, Debatin KM: MycN sensitizes neuroblastoma cells for drug-induced apoptosis. Oncogene 1999, 18(7):1479-1486.
-
(1999)
Oncogene
, vol.18
, Issue.7
, pp. 1479-1486
-
-
Fulda, S.1
Lutz, W.2
Schwab, M.3
Debatin, K.M.4
-
28
-
-
78649338141
-
Autophagy and the integrated stress response
-
Kroemer G, Marino G, Levine B: Autophagy and the integrated stress response. Mol Cell 2010, 40(2):280-293.
-
(2010)
Mol Cell
, vol.40
, Issue.2
, pp. 280-293
-
-
Kroemer, G.1
Marino, G.2
Levine, B.3
-
29
-
-
0442323561
-
Autophagy: in sickness and in health
-
Cuervo AM: Autophagy: in sickness and in health. Trends Cell Biol 2004, 14(2):70-77.
-
(2004)
Trends Cell Biol
, vol.14
, Issue.2
, pp. 70-77
-
-
Cuervo, A.M.1
-
30
-
-
62449287501
-
The paradox of autophagy and its implication in cancer etiology and therapy
-
Eisenberg-Lerner A, Kimchi A: The paradox of autophagy and its implication in cancer etiology and therapy. Apoptosis 2009, 14(4):376-391.
-
(2009)
Apoptosis
, vol.14
, Issue.4
, pp. 376-391
-
-
Eisenberg-Lerner, A.1
Kimchi, A.2
-
31
-
-
84870810698
-
The Hedgehog signalling pathway regulates autophagy
-
Jimenez-Sanchez M, Menzies FM, Chang YY, Simecek N, Neufeld TP, Rubinsztein DC: The Hedgehog signalling pathway regulates autophagy. Nat Commun 2012, 3:1200.
-
(2012)
Nat Commun
, vol.3
, pp. 1200
-
-
Jimenez-Sanchez, M.1
Menzies, F.M.2
Chang, Y.Y.3
Simecek, N.4
Neufeld, T.P.5
Rubinsztein, D.C.6
-
32
-
-
84870509456
-
Sonic hedgehog promotes autophagy of vascular smooth muscle cells
-
Li H, Li J, Li Y, Singh P, Cao L, Xu LJ, Li D, Wang Y, Xie Z, Gui Y, Zheng XL: Sonic hedgehog promotes autophagy of vascular smooth muscle cells. Am J Physiol Heart Circ Physiol 2012, 303(11):H1319-H1331.
-
(2012)
Am J Physiol Heart Circ Physiol
, vol.303
, Issue.11
, pp. H1319-H1331
-
-
Li, H.1
Li, J.2
Li, Y.3
Singh, P.4
Cao, L.5
Xu, L.J.6
Li, D.7
Wang, Y.8
Xie, Z.9
Gui, Y.10
Zheng, X.L.11
-
33
-
-
84879919205
-
Histone deacetylase 10 promotes autophagy-mediated cell survival
-
Oehme I, Linke JP, Bock BC, Milde T, Lodrini M, Hartenstein B, Wiegand I, Eckert C, Roth W, Kool M, Kaden S, Grone HJ, Schulte JH, Lindner S, Hamacher-Brady A, Brady NR, Deubzer HE, Witt O: Histone deacetylase 10 promotes autophagy-mediated cell survival. Proc Natl Acad Sci U S A 2013, 110(28):E2592-E2601.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.28
, pp. E2592-E2601
-
-
Oehme, I.1
Linke, J.P.2
Bock, B.C.3
Milde, T.4
Lodrini, M.5
Hartenstein, B.6
Wiegand, I.7
Eckert, C.8
Roth, W.9
Kool, M.10
Kaden, S.11
Grone, H.J.12
Schulte, J.H.13
Lindner, S.14
Hamacher-Brady, A.15
Brady, N.R.16
Deubzer, H.E.17
Witt, O.18
|