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Volumn 46, Issue 1, 2015, Pages 93-107

NK cells are activated in amnestic mild cognitive impairment but not in mild Alzheimer's disease patients

Author keywords

Alzheimer's disease; amnestic mild cognitive impairment; cell cytotoxicity; chemotaxis; natural killer cells; phenotyping; toll like receptors

Indexed keywords

AMYLOID BETA PROTEIN; ANTIGEN; CD107 ANTIGEN; CD16 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR7; FAS ANTIGEN; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 12; INTERLEUKIN 12 RECEPTOR BETA1; INTERLEUKIN 12 RECEPTOR BETA2; INTERLEUKIN 18; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; NATURAL KILLER CELL RECEPTOR NKG2A; SECONDARY LYMPHOID TISSUE CHEMOKINE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; APOLIPOPROTEIN E4; CYTOKINE; CYTOKINE RECEPTOR; TLR4 PROTEIN, HUMAN;

EID: 84929313637     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-143054     Document Type: Article
Times cited : (44)

References (71)
  • 1
    • 84860425072 scopus 로고    scopus 로고
    • Amyloid and Alzheimer's disease: Inside and out
    • Tam JH, Pasternak SH (2012) Amyloid and Alzheimer's disease: Inside and out. Can J Neurol Sci 39, 286-298.
    • (2012) Can J Neurol Sci , vol.39 , pp. 286-298
    • Tam, J.H.1    Pasternak, S.H.2
  • 4
    • 69949107465 scopus 로고    scopus 로고
    • The unsolved relationship of brain aging and late-onset Alzheimer disease
    • Kern A, Behl C (2009) The unsolved relationship of brain aging and late-onset Alzheimer disease. Biochim Biophys Acta 1790, 1124-1132.
    • (2009) Biochim Biophys Acta , vol.1790 , pp. 1124-1132
    • Kern, A.1    Behl, C.2
  • 6
    • 84878486664 scopus 로고    scopus 로고
    • Genetics of familial and sporadic Alzheimer's disease
    • Piaceri I, Nacmias B, Sorbi S (2013) Genetics of familial and sporadic Alzheimer's disease. Front Biosci (Elite Ed) 5, 167-177.
    • (2013) Front Biosci (Elite Ed) , vol.5 , pp. 167-177
    • Piaceri, I.1    Nacmias, B.2    Sorbi, S.3
  • 7
    • 84897954407 scopus 로고    scopus 로고
    • Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers
    • Reitz C, Mayeux R (2014) Alzheimer disease: Epidemiology, diagnostic criteria, risk factors and biomarkers. Biochem Pharmacol 88, 640-651.
    • (2014) Biochem Pharmacol , vol.88 , pp. 640-651
    • Reitz, C.1    Mayeux, R.2
  • 9
    • 84856390353 scopus 로고    scopus 로고
    • Emerging roles of pathogens in Alzheimer disease
    • Miklossy J (2011) Emerging roles of pathogens in Alzheimer disease. Expert Rev Mol Med 13, e30.
    • (2011) Expert Rev Mol Med , vol.13 , pp. e30
    • Miklossy, J.1
  • 10
    • 84874488436 scopus 로고    scopus 로고
    • Can infections cause Alzheimer's disease?
    • Mawanda F, Wallace R (2013) Can infections cause Alzheimer's disease? Epidemiol Rev 35, 161-180.
    • (2013) Epidemiol Rev , vol.35 , pp. 161-180
    • Mawanda, F.1    Wallace, R.2
  • 11
    • 84865660409 scopus 로고    scopus 로고
    • Mild cognitive impairment in older adults
    • Geda YE (2012) Mild cognitive impairment in older adults. Curr Psychiatry Rep 14, 320-327.
    • (2012) Curr Psychiatry Rep , vol.14 , pp. 320-327
    • Geda, Y.E.1
  • 12
    • 34447303785 scopus 로고    scopus 로고
    • Alzheimer's disease and mild cognitive impairment
    • Kelley BJ, Petersen RC (2007) Alzheimer's disease and mild cognitive impairment. Neurol Clin 25, 577-609.
    • (2007) Neurol Clin , vol.25 , pp. 577-609
    • Kelley, B.J.1    Petersen, R.C.2
  • 16
    • 84872699164 scopus 로고    scopus 로고
    • Review: Systemic inflammation and Alzheimer's disease
    • Holmes C (2013) Review: Systemic inflammation and Alzheimer's disease. Neuropathol Appl Neurobiol 39, 51-68.
    • (2013) Neuropathol Appl Neurobiol , vol.39 , pp. 51-68
    • Holmes, C.1
  • 18
    • 80054110588 scopus 로고    scopus 로고
    • Autoimmune and inflammatory mechanisms of CNS damage
    • Kapadia M, Sakic B (2011) Autoimmune and inflammatory mechanisms of CNS damage. Prog Neurobiol 95, 301-333.
    • (2011) Prog Neurobiol , vol.95 , pp. 301-333
    • Kapadia, M.1    Sakic, B.2
  • 19
    • 84886684931 scopus 로고    scopus 로고
    • The innate immune system in Alzheimer's disease
    • Boutajangout A, Wisniewski T (2013) The innate immune system in Alzheimer's disease. Int J Cell Biol 2013, 576383.
    • (2013) Int J Cell Biol , vol.2013 , pp. 576383
    • Boutajangout, A.1    Wisniewski, T.2
  • 20
    • 84856303487 scopus 로고    scopus 로고
    • Systemic and central immunity in Alzheimer's disease: Therapeutic implications
    • Butchart J, Holmes C (2012) Systemic and central immunity in Alzheimer's disease: Therapeutic implications. CNS Neurosci Ther 18, 64-76.
    • (2012) CNS Neurosci Ther , vol.18 , pp. 64-76
    • Butchart, J.1    Holmes, C.2
  • 21
    • 84903269246 scopus 로고    scopus 로고
    • Innate immune activation in neurodegenerative disease
    • Heneka MT, Kummer MP, Latz E (2014) Innate immune activation in neurodegenerative disease. Nat Rev Immunol 14, 463-477.
    • (2014) Nat Rev Immunol , vol.14 , pp. 463-477
    • Heneka, M.T.1    Kummer, M.P.2    Latz, E.3
  • 22
    • 66449130960 scopus 로고    scopus 로고
    • Regulation of innate immune responses in the brain
    • Rivest S (2009) Regulation of innate immune responses in the brain. Nat Rev Immunol 9, 429-439.
    • (2009) Nat Rev Immunol , vol.9 , pp. 429-439
    • Rivest, S.1
  • 24
    • 68849105814 scopus 로고    scopus 로고
    • Oncogenic stress sensed by the immune system: Role of natural killer cell receptors
    • Raulet DH, Guerra N (2009) Oncogenic stress sensed by the immune system: Role of natural killer cell receptors. Nat Rev Immunol 9, 568-580.
    • (2009) Nat Rev Immunol , vol.9 , pp. 568-580
    • Raulet, D.H.1    Guerra, N.2
  • 25
    • 79951912532 scopus 로고    scopus 로고
    • Four faces of cellular senescence
    • Rodier F, Campisi J (2011) Four faces of cellular senescence. J Cell Biol 192, 547-556.
    • (2011) J Cell Biol , vol.192 , pp. 547-556
    • Rodier, F.1    Campisi, J.2
  • 26
    • 50949124847 scopus 로고    scopus 로고
    • Human natural killer cells
    • Caligiuri MA (2008) Human natural killer cells. Blood 112, 461-469.
    • (2008) Blood , vol.112 , pp. 461-469
    • Caligiuri, M.A.1
  • 27
    • 84875528678 scopus 로고    scopus 로고
    • Controlling natural killer cell responses: Integration of signals for activation and inhibition
    • Long EO, Kim HS, Liu D, Peterson ME, Rajagopalan S (2013) Controlling natural killer cell responses: Integration of signals for activation and inhibition. Annu Rev Immunol 31, 227-258.
    • (2013) Annu Rev Immunol , vol.31 , pp. 227-258
    • Long, E.O.1    Kim, H.S.2    Liu, D.3    Peterson, M.E.4    Rajagopalan, S.5
  • 28
    • 84874218764 scopus 로고    scopus 로고
    • Human NK cell lytic granules and regulation of their exocytosis
    • Article 335
    • Krzewski K, Coligan JE (2012) Human NK cell lytic granules and regulation of their exocytosis. Front Immunol 3, Article 335.
    • (2012) Front Immunol , vol.3
    • Krzewski, K.1    Coligan, J.E.2
  • 33
    • 0025884935 scopus 로고
    • Reduced natural killer cell activity in patients with dementia of the Alzheimer type
    • Araga S, Kagimoto H, Funamoto K, Takahashi K (1991) Reduced natural killer cell activity in patients with dementia of the Alzheimer type. Acta Neurol Scand 84, 259-263.
    • (1991) Acta Neurol Scand , vol.84 , pp. 259-263
    • Araga, S.1    Kagimoto, H.2    Funamoto, K.3    Takahashi, K.4
  • 35
    • 0031820045 scopus 로고    scopus 로고
    • Increased natural killer cell cytotoxicity in Alzheimer's disease may involve protein kinase C dysregula-tion
    • Solerte SB, Fioravanti M, Pascale A, Ferrari E, Govoni S, Battaini F (1998) Increased natural killer cell cytotoxicity in Alzheimer's disease may involve protein kinase C dysregula-tion. Neurobiol Aging 19, 191-199.
    • (1998) Neurobiol Aging , vol.19 , pp. 191-199
    • Solerte, S.B.1    Fioravanti, M.2    Pascale, A.3    Ferrari, E.4    Govoni, S.5    Battaini, F.6
  • 36
    • 0031944880 scopus 로고    scopus 로고
    • Decreased immunosuppressive effect of cortisol on natural killer cytotoxic activity in senile dementia of the Alzheimer type
    • Solerte SB, Cerutti N, Severgnini S, Rondanelli M, Ferrari E, Fioravanti M (1998) Decreased immunosuppressive effect of cortisol on natural killer cytotoxic activity in senile dementia of the Alzheimer type. Dement Geriatr Cogn Disord 9, 149-156.
    • (1998) Dement Geriatr Cogn Disord , vol.9 , pp. 149-156
    • Solerte, S.B.1    Cerutti, N.2    Severgnini, S.3    Rondanelli, M.4    Ferrari, E.5    Fioravanti, M.6
  • 37
    • 0036127630 scopus 로고    scopus 로고
    • Mental deterioration correlates with response of natural killer (NK) cell activity to physiological modifiers in patients with short history of Alzheimer's disease
    • Masera RG, Prolo P, Sartori ML, Staurenghi A, Griot G, Ravizza L, Dovio A, Chiappelli F, Angeli A (2002) Mental deterioration correlates with response of natural killer (NK) cell activity to physiological modifiers in patients with short history of Alzheimer's disease. Psychoneuroendocrinol 27, 447-461.
    • (2002) Psychoneuroendocrinol , vol.27 , pp. 447-461
    • Masera, R.G.1    Prolo, P.2    Sartori, M.L.3    Staurenghi, A.4    Griot, G.5    Ravizza, L.6    Dovio, A.7    Chiappelli, F.8    Angeli, A.9
  • 38
    • 79953212988 scopus 로고    scopus 로고
    • Atorvastatin prevents age-related and amyloid-beta-induced microglial activation by blocking interferon-gamma release from natural killer cells in the brain
    • Lyons A, Murphy KJ, Clarke R, Lynch MA (2011) Atorvastatin prevents age-related and amyloid-beta-induced microglial activation by blocking interferon-gamma release from natural killer cells in the brain. J Neuroinflammation 8, 27.
    • (2011) J Neuroinflammation , vol.8 , pp. 27
    • Lyons, A.1    Murphy, K.J.2    Clarke, R.3    Lynch, M.A.4
  • 43
    • 0016823810 scopus 로고
    • Mini-mental state. A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR (1975) "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12, 189-198.
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 46
    • 0036791488 scopus 로고    scopus 로고
    • IL-12 enhances the natural killer cell cytokine response to ab-coated tumor cells
    • Parihar R, Dierksheide J, Hu Y, Carson WE (2002) IL-12 enhances the natural killer cell cytokine response to ab-coated tumor cells. J Clin Invest 110, 983-992.
    • (2002) J Clin Invest , vol.110 , pp. 983-992
    • Parihar, R.1    Dierksheide, J.2    Hu, Y.3    Carson, W.E.4
  • 47
    • 84873148889 scopus 로고    scopus 로고
    • Increased expression of interleukin-18 receptor in blood cells of subjects with mild cognitive impairment and alzheimer's disease
    • Salani F, Ciaramella A, Bizzoni F, Assogna F, Caltagirone C, Spalletta G, Bossu P (2013) Increased expression of interleukin-18 receptor in blood cells of subjects with mild cognitive impairment and alzheimer's disease. Cytokine 61, 360-363.
    • (2013) Cytokine , vol.61 , pp. 360-363
    • Salani, F.1    Ciaramella, A.2    Bizzoni, F.3    Assogna, F.4    Caltagirone, C.5    Spalletta, G.6    Bossu, P.7
  • 49
    • 22544473593 scopus 로고    scopus 로고
    • TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-y production
    • Hart OM, Athie-Morales V, O'Connor GM, Gardiner CM (2005) TLR7/8-mediated activation of human NK cells results in accessory cell-dependent IFN-y production. J Immunol 175, 1636-1642.
    • (2005) J Immunol , vol.175 , pp. 1636-1642
    • Hart, O.M.1    Athie-Morales, V.2    O'Connor, G.M.3    Gardiner, C.M.4
  • 50
    • 33750470437 scopus 로고    scopus 로고
    • The direct effects of toll-like receptor ligands on human NK cell cytokine production and cytotoxicity
    • Lauzon NM, Mian F, MacKenzie R, Ashkar AA (2006) The direct effects of toll-like receptor ligands on human NK cell cytokine production and cytotoxicity. Cell Immunol 241, 102-112.
    • (2006) Cell Immunol , vol.241 , pp. 102-112
    • Lauzon, N.M.1    Mian, F.2    MacKenzie, R.3    Ashkar, A.A.4
  • 51
    • 37349069999 scopus 로고    scopus 로고
    • Toll-like receptors 2 and 4 mediate Aβ(1-42) activation of the innate immune response in a human monocytic cell line
    • Udan ML, Ajit D, Crouse NR, Nichols MR (2008) Toll-like receptors 2 and 4 mediate Aβ(1-42) activation of the innate immune response in a human monocytic cell line. J Neu-rochem 104, 524-533.
    • (2008) J Neu-rochem , vol.104 , pp. 524-533
    • Udan, M.L.1    Ajit, D.2    Crouse, N.R.3    Nichols, M.R.4
  • 52
    • 78649259701 scopus 로고    scopus 로고
    • Toll-like receptor 3: Involvement with exogenous and endogenous RNA
    • Amarante MK, Watanabe MA (2010) Toll-like receptor 3: Involvement with exogenous and endogenous RNA. Int Rev Immunol 29, 557-573.
    • (2010) Int Rev Immunol , vol.29 , pp. 557-573
    • Amarante, M.K.1    Watanabe, M.A.2
  • 53
    • 77957970532 scopus 로고    scopus 로고
    • Role of chemokines in the biology of natural killer cells
    • Maghazachi AA (2010) Role of chemokines in the biology of natural killer cells. Curr Top Microbiol Immunol 341, 37-58.
    • (2010) Curr Top Microbiol Immunol , vol.341 , pp. 37-58
    • Maghazachi, A.A.1
  • 57
    • 42649086026 scopus 로고    scopus 로고
    • CCR7 and its ligands: Balancing immunity and tolerance
    • Forster R, Davalos-Misslitz AC, Rot A (2008) CCR7 and its ligands: Balancing immunity and tolerance. Nat Rev Immunol 8, 362-371.
    • (2008) Nat Rev Immunol , vol.8 , pp. 362-371
    • Forster, R.1    Davalos-Misslitz, A.C.2    Rot, A.3
  • 59
    • 84902008578 scopus 로고    scopus 로고
    • Human CNS immune senescence and neurodegeneration
    • Streit WJ, Xue QS (2014) Human CNS immune senescence and neurodegeneration. Curr Opin Immunol 29, 93-96.
    • (2014) Curr Opin Immunol , vol.29 , pp. 93-96
    • Streit, W.J.1    Xue, Q.S.2
  • 60
    • 35448979876 scopus 로고    scopus 로고
    • Altered plasma cytokine levels in Alzheimer's disease: Correlation with the disease progression
    • Motta M, Imbesi R, Di Rosa M, Stivala F, Malaguarnera L (2007) Altered plasma cytokine levels in Alzheimer's disease: Correlation with the disease progression. Immunol Lett 114, 46-51.
    • (2007) Immunol Lett , vol.114 , pp. 46-51
    • Motta, M.1    Imbesi, R.2    Di Rosa, M.3    Stivala, F.4    Malaguarnera, L.5
  • 63
    • 33749490571 scopus 로고    scopus 로고
    • Innate immune recognition of, and regulation by, DNA
    • Ishii KJ, Akira S (2006) Innate immune recognition of, and regulation by, DNA. Trends Immunol 27, 525-532.
    • (2006) Trends Immunol , vol.27 , pp. 525-532
    • Ishii, K.J.1    Akira, S.2
  • 64
    • 73649137143 scopus 로고    scopus 로고
    • Microglia activated with the toll-like receptor 9 ligand CpG attenuate oligomeric amyloid β neurotoxicity in in vitro and in vivo models of Alzheimer's disease
    • Doi Y, Mizuno T, Maki Y, Jin S, Mizoguchi H, Ikeyama M, Doi M, Michikawa M, Takeuchi H, Suzumura A (2009) Microglia activated with the toll-like receptor 9 ligand CpG attenuate oligomeric amyloid β neurotoxicity in in vitro and in vivo models of Alzheimer's disease. Am J Pathol 175, 2121-2132.
    • (2009) Am J Pathol , vol.175 , pp. 2121-2132
    • Doi, Y.1    Mizuno, T.2    Maki, Y.3    Jin, S.4    Mizoguchi, H.5    Ikeyama, M.6    Doi, M.7    Michikawa, M.8    Takeuchi, H.9    Suzumura, A.10
  • 68
    • 48549099675 scopus 로고    scopus 로고
    • Serial killing of tumor cells by human natural killer cells-enhancement by therapeutic antibodies
    • Bhat R, Watzl C (2007) Serial killing of tumor cells by human natural killer cells-enhancement by therapeutic antibodies. PLoS One 2, e326.
    • (2007) PLoS One , vol.2 , pp. e326
    • Bhat, R.1    Watzl, C.2
  • 70
    • 84877754164 scopus 로고    scopus 로고
    • Bi(o)communications among peripheral blood fractions: A focus on NK and NKT cell biology in rheumatoid arthritis
    • Aggarwal A, Sharma A, Bhatnagar A (2013) Bi(o)communications among peripheral blood fractions: A focus on NK and NKT cell biology in rheumatoid arthritis. Autoimmunity 46, 238-250.
    • (2013) Autoimmunity , vol.46 , pp. 238-250
    • Aggarwal, A.1    Sharma, A.2    Bhatnagar, A.3


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