The non-muscle-myosin-II heavy chain Myh9 mediates colitis-induced epithelium injury by restricting Lgr5+ stem cells

Nature Communications

Volumn 6, Issue , 2015, Pages

  Zhao, Bing ^a   Qi, Zhen ^a   Li, Yehua ^a   Wang, Chongkai ^b   Fu, Wei ^b   Chen, Ye Guang ^a  

^a Peking University   (China)

^b PEKING UNIVERSITY THIRD HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BLEBBISTATIN; DEXTRAN SULFATE; G PROTEIN COUPLED RECEPTOR; MYOSIN II; NON MUSCLE MYOSIN II HEAVY CHAIN MYH9; P21 ACTIVATED KINASE 1; PROTEIN KINASE B; PROTEIN LGR5; RAC1 PROTEIN; UNCLASSIFIED DRUG; 4 AMINO 6 [2 [[4 (DIETHYLAMINO) 1 METHYLBUTYL]AMINO] 6 METHYL 4 PYRIMIDINYL] 2 METHYLQUINOLINE; AMINOQUINOLINE DERIVATIVE; FUSED HETEROCYCLIC RINGS; GREEN FLUORESCENT PROTEIN; LGR5 PROTEIN, MOUSE; MYH9 PROTEIN, MOUSE; MYOSIN IIA; NEUROPEPTIDE; P21 ACTIVATED KINASE; PAK1 PROTEIN, MOUSE; PYRIMIDINE DERIVATIVE; RAC1 PROTEIN, MOUSE;

GASTROENTERITIS; GERM CELL; GROWTH RATE; HOMEOSTASIS; INJURY; MUSCLE; SURVIVORSHIP;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL SURVIVAL; COLITIS; CONTROLLED STUDY; CYTOPLASM; DESCENDING COLON; DIGESTIVE SYSTEM INJURY; ENZYME ACTIVATION; GENE DELETION; HOMEOSTASIS; HUMAN; HUMAN TISSUE; INTESTINE CRYPT; INTESTINE EPITHELIUM; MALE; MOUSE; MYH9 GENE; NONHUMAN; PLURIPOTENT STEM CELL; 3T3 CELL LINE; ANIMAL; CHEMISTRY; CYTOLOGY; EPITHELIUM; GENE EXPRESSION REGULATION; INTESTINE; INTESTINE MUCOSA; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; STEM CELL;

MUS;

ALLELES; AMINOQUINOLINES; ANIMALS; CELL SURVIVAL; COLITIS; EPITHELIUM; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; HETEROCYCLIC COMPOUNDS WITH 4 OR MORE RINGS; INTESTINAL MUCOSA; INTESTINES; MALE; MICE; MYOSIN TYPE II; NEUROPEPTIDES; NIH 3T3 CELLS; NONMUSCLE MYOSIN TYPE IIA; P21-ACTIVATED KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PYRIMIDINES; RAC1 GTP-BINDING PROTEIN; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; STEM CELLS;

EID: 84929310515     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms8166     Document Type: Article

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