GMI, an immunomodulatory protein from ganoderma microsporum, potentiates cisplatin-induced apoptosis via autophagy in lung cancer cells

Molecular Pharmaceutics

Volumn 12, Issue 5, 2015, Pages 1534-1543

  Hsin, I Lun ^a   Ou, Chu Chyn ^a   Wu, Ming Fang ^a,b   Jan, Ming Shiou ^a   Hsiao, Yi Min ^c   Lin, Ching Hsiung ^a,d,e   Ko, Jiunn Liang ^a,b  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^d CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^e CHANG JUNG CHRISTIAN UNIVERSITY   (Taiwan)

Author keywords

apoptosis; autophagy; caspase 7; cisplatin; GMI

Indexed keywords

3 METHYLADENINE; CASPASE 3; CASPASE 7; CHLOROQUINE; CISPLATIN; GMI; HISTONE H2AX; HOE 33342; IMMUNOMODULATING AGENT; LIPOCORTIN 5; MAMMALIAN TARGET OF RAPAMYCIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROPIDIUM IODIDE; PROTEIN KINASE B; SHORT HAIRPIN RNA; SURVIVIN; UNCLASSIFIED DRUG; FUNGAL PROTEIN;

A549 CELL LINE; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CANCER CELL; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; GANODERMA; GANODERMA MICROSPORUM; GENE SILENCING; LOW DRUG DOSE; LUNG CANCER; MTT ASSAY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING; CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; HUMAN; LUNG TUMOR; METABOLISM;

APOPTOSIS; AUTOPHAGY; CASPASE 3; CASPASE 7; CELL LINE; CELL SURVIVAL; CISPLATIN; FUNGAL PROTEINS; GANODERMA; HUMANS; LUNG NEOPLASMS;

EID: 84929222907     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp500840z     Document Type: Article

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