Cordycepin induces apoptosis of CGTH W-2 thyroid carcinoma cells through the calcium-calpain-caspase 7-PARP pathway

Journal of Agricultural and Food Chemistry

Volumn 58, Issue 22, 2010, Pages 11645-11652

  Chen, Ying ^a   Chen, Yung Chia ^a   Lin, Yen Tung ^a   Huang, Shih Horng ^b,c   Wang, Seu Mei ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b YUAN ZE UNIVERSITY   (Taiwan)

^c Far Eastern Hospital   (Taiwan)

Author keywords

apoptosis; Cordycepin; signaling mechanism; thyroid carcinoma cells

Indexed keywords

ADENOSINE RECEPTOR; ANTICANCER EFFECTS; ANTITUMOR EFFECT; APOPTOSIS; APOPTOTIC EFFECTS; CALPAIN ACTIVATION; CALPAINS; CASPASES; CELL VIABILITY; CORDYCEPIN; CORDYCEPS SINENSIS; INDUCED APOPTOSIS; INTRACELLULAR CALCIUM LEVELS; POLY(ADP-RIBOSE) POLYMERASE; POLYADENYLATION; SIGNALING MECHANISM; SMALL INTERFERING RNA; THYROID CARCINOMA;

CALCIUM; CELL CULTURE; DRUG PRODUCTS; RNA; SIGNALING;

CELL DEATH;

ANTINEOPLASTIC AGENT; CALCIUM; CALPAIN; CASPASE 7; CORDYCEPIN; DEOXYADENOSINE DERIVATIVE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

APOPTOSIS; ARTICLE; CHEMISTRY; CORDYCEPS; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; THYROID TUMOR; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CALCIUM; CALPAIN; CASPASE 7; CELL LINE, TUMOR; CORDYCEPS; DEOXYADENOSINES; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; POLY(ADP-RIBOSE) POLYMERASES; SIGNAL TRANSDUCTION; THYROID NEOPLASMS;

CORDYCEPS SINENSIS;

EID: 78649232334     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf1028976     Document Type: Article

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