메뉴 건너뛰기




Volumn 213, Issue 2, 2015, Pages 453-461

Substance P and the regulation of inflammation in infections and inflammatory bowel disease

Author keywords

Helminths; Inflammatory bowel disease; Neurokinin 1 receptor; Substance p

Indexed keywords

GAMMA INTERFERON; HEMOKININ 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 23; NEUROKININ 1 RECEPTOR; NEUROPEPTIDE; REGULATOR PROTEIN; SUBSTANCE P; T LYMPHOCYTE RECEPTOR; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE;

EID: 84929209748     PISSN: 17481708     EISSN: 17481716     Source Type: Journal    
DOI: 10.1111/apha.12428     Document Type: Review
Times cited : (38)

References (88)
  • 1
    • 0027312928 scopus 로고
    • Inhibition of murine intestinal inflammation by anti-substance P antibody
    • Agro, A. & Stanisz, A.M. 1993. Inhibition of murine intestinal inflammation by anti-substance P antibody. Reg Immunol 5, 120-126.
    • (1993) Reg Immunol , vol.5 , pp. 120-126
    • Agro, A.1    Stanisz, A.M.2
  • 2
    • 84862207375 scopus 로고    scopus 로고
    • Innate immune properties of selected human neuropeptides against Moraxella catarrhalis and nontypeable Haemophilus influenzae
    • Augustyniak, D., Jankowski, A., Mackiewicz, P., Skowyra, A., Gutowicz, J. & Drulis-Kawa, Z. 2012. Innate immune properties of selected human neuropeptides against Moraxella catarrhalis and nontypeable Haemophilus influenzae. BMC Immunol 13, 24.
    • (2012) BMC Immunol , vol.13 , pp. 24
    • Augustyniak, D.1    Jankowski, A.2    Mackiewicz, P.3    Skowyra, A.4    Gutowicz, J.5    Drulis-Kawa, Z.6
  • 4
    • 0026486215 scopus 로고
    • Granuloma T lymphocytes in murine schistosomiasis mansoni have somatostatin receptors and respond to somatostatin with decreased IFN-gamma secretion
    • Blum, A.M., Metwali, A., Mathew, R.C., Cook, G., Elliott, D. & Weinstock, J.V. 1992. Granuloma T lymphocytes in murine schistosomiasis mansoni have somatostatin receptors and respond to somatostatin with decreased IFN-gamma secretion. J Immunol 149, 3621-3626.
    • (1992) J Immunol , vol.149 , pp. 3621-3626
    • Blum, A.M.1    Metwali, A.2    Mathew, R.C.3    Cook, G.4    Elliott, D.5    Weinstock, J.V.6
  • 5
    • 0027313356 scopus 로고
    • Substance P modulates antigen-induced, IFN-gamma production in murine Schistosomiasis mansoni
    • Blum, A.M., Metwali, A., Cook, G., Mathew, R.C., Elliott, D. & Weinstock, J.V. 1993a. Substance P modulates antigen-induced, IFN-gamma production in murine Schistosomiasis mansoni. J Immunol 151, 225-233.
    • (1993) J Immunol , vol.151 , pp. 225-233
    • Blum, A.M.1    Metwali, A.2    Cook, G.3    Mathew, R.C.4    Elliott, D.5    Weinstock, J.V.6
  • 6
    • 0027131379 scopus 로고
    • Substance P and somatostatin can modulate the amount of IgG2a secreted in response to schistosome egg antigens in murine schistosomiasis mansoni
    • Blum, A.M., Metwali, A., Mathew, R.C., Elliott, D. & Weinstock, J.V. 1993b. Substance P and somatostatin can modulate the amount of IgG2a secreted in response to schistosome egg antigens in murine schistosomiasis mansoni. J Immunol 151, 6994-7004.
    • (1993) J Immunol , vol.151 , pp. 6994-7004
    • Blum, A.M.1    Metwali, A.2    Mathew, R.C.3    Elliott, D.4    Weinstock, J.V.5
  • 9
    • 0035069996 scopus 로고    scopus 로고
    • Interleukin 12 and antigen independently induce substance P receptor expression in T cells in murine schistosomiasis mansoni
    • Blum, A.M., Metwali, A., Crawford, C., Li, J., Qadir, K., Elliott, D.E. & Weinstock, J.V. 2001. Interleukin 12 and antigen independently induce substance P receptor expression in T cells in murine schistosomiasis mansoni. FASEB J 15, 950-957.
    • (2001) FASEB J , vol.15 , pp. 950-957
    • Blum, A.M.1    Metwali, A.2    Crawford, C.3    Li, J.4    Qadir, K.5    Elliott, D.E.6    Weinstock, J.V.7
  • 11
    • 48849086421 scopus 로고    scopus 로고
    • Interleukin-12 (IL-12) and IL-23 induction of substance P synthesis in murine T cells and macrophages is subject to IL-10 and transforming growth factor beta regulation
    • Blum, A., Setiawan, T., Hang, L., Stoyanoff, K. & Weinstock, J.V. 2008. Interleukin-12 (IL-12) and IL-23 induction of substance P synthesis in murine T cells and macrophages is subject to IL-10 and transforming growth factor beta regulation. Infect Immun 76, 3651-3656.
    • (2008) Infect Immun , vol.76 , pp. 3651-3656
    • Blum, A.1    Setiawan, T.2    Hang, L.3    Stoyanoff, K.4    Weinstock, J.V.5
  • 12
    • 4444223486 scopus 로고    scopus 로고
    • Tachykinin-modulated anti-viral responses
    • Bost, K.L. 2004. Tachykinin-modulated anti-viral responses. Front Biosci 9, 1994-1998.
    • (2004) Front Biosci , vol.9 , pp. 1994-1998
    • Bost, K.L.1
  • 13
    • 0026725160 scopus 로고
    • Modulation of the mRNAs encoding substance P and its receptor in rat macrophages by LPS
    • Bost, K.L., Breeding, S.A. & Pascual, D.W. 1992. Modulation of the mRNAs encoding substance P and its receptor in rat macrophages by LPS. Reg Immunol 4, 105-112.
    • (1992) Reg Immunol , vol.4 , pp. 105-112
    • Bost, K.L.1    Breeding, S.A.2    Pascual, D.W.3
  • 14
    • 0030896270 scopus 로고    scopus 로고
    • Increased substance P responses in dorsal root ganglia and intestinal macrophages during Clostridium difficile toxin A enteritis in rats
    • Castagliuolo, I., Keates, A.C., Qiu, B., Kelly, C.P., Nikulasson, S., Leeman, S.E. & Pothoulakis, C. 1997. Increased substance P responses in dorsal root ganglia and intestinal macrophages during Clostridium difficile toxin A enteritis in rats. Proc Natl Acad Sci USA 94, 4788-4793.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4788-4793
    • Castagliuolo, I.1    Keates, A.C.2    Qiu, B.3    Kelly, C.P.4    Nikulasson, S.5    Leeman, S.E.6    Pothoulakis, C.7
  • 16
    • 66949127237 scopus 로고    scopus 로고
    • Endothelin-converting enzyme 1 promotes re-sensitization of neurokinin 1 receptor-dependent neurogenic inflammation
    • Cattaruzza, F., Cottrell, G.S., Vaksman, N. & Bunnett, N.W. 2009. Endothelin-converting enzyme 1 promotes re-sensitization of neurokinin 1 receptor-dependent neurogenic inflammation. Br J Pharmacol 156, 730-739.
    • (2009) Br J Pharmacol , vol.156 , pp. 730-739
    • Cattaruzza, F.1    Cottrell, G.S.2    Vaksman, N.3    Bunnett, N.W.4
  • 17
    • 50949116628 scopus 로고    scopus 로고
    • Neurogenic exacerbation of microglial and astrocyte responses to Neisseria meningitidis and Borrelia burgdorferi
    • Chauhan, V.S., Sterka, D.G. Jr, Gray, D.L., Bost, K.L. & Marriott, I. 2008. Neurogenic exacerbation of microglial and astrocyte responses to Neisseria meningitidis and Borrelia burgdorferi. J Immunol 180, 8241-8249.
    • (2008) J Immunol , vol.180 , pp. 8241-8249
    • Chauhan, V.S.1    Sterka Jr., D.G.2    Gray, D.L.3    Bost, K.L.4    Marriott, I.5
  • 18
    • 79959563961 scopus 로고    scopus 로고
    • Prophylactic and therapeutic targeting of the neurokinin-1 receptor limits neuroinflammation in a murine model of pneumococcal meningitis
    • Chauhan, V.S., Kluttz, J.M., Bost, K.L. & Marriott, I. 2011. Prophylactic and therapeutic targeting of the neurokinin-1 receptor limits neuroinflammation in a murine model of pneumococcal meningitis. J Immunol 186, 7255-7263.
    • (2011) J Immunol , vol.186 , pp. 7255-7263
    • Chauhan, V.S.1    Kluttz, J.M.2    Bost, K.L.3    Marriott, I.4
  • 19
    • 0028296050 scopus 로고
    • Molecular evidence that granuloma T lymphocytes in murine schistosomiasis mansoni express an authentic substance P (NK-1) receptor
    • Cook, G.A., Elliott, D., Metwali, A., Blum, A.M., Sandor, M., Lynch, R. & Weinstock, J.V. 1994. Molecular evidence that granuloma T lymphocytes in murine schistosomiasis mansoni express an authentic substance P (NK-1) receptor. J Immunol 152, 1830-1835.
    • (1994) J Immunol , vol.152 , pp. 1830-1835
    • Cook, G.A.1    Elliott, D.2    Metwali, A.3    Blum, A.M.4    Sandor, M.5    Lynch, R.6    Weinstock, J.V.7
  • 22
    • 79251535010 scopus 로고    scopus 로고
    • Neurokinin-1 receptor: functional significance in the immune system in reference to selected infections and inflammation
    • Douglas, S.D. & Leeman, S.E. 2011. Neurokinin-1 receptor: functional significance in the immune system in reference to selected infections and inflammation. Ann N Y Acad Sci 1217, 83-95.
    • (2011) Ann N Y Acad Sci , vol.1217 , pp. 83-95
    • Douglas, S.D.1    Leeman, S.E.2
  • 24
    • 36749032243 scopus 로고    scopus 로고
    • Substance P is associated with heart enlargement and apoptosis in murine dilated cardiomyopathy induced by Taenia crassiceps infection
    • D'Souza, M., Garza, M.A., Xie, M., Weinstock, J., Xiang, Q. & Robinson, P. 2007. Substance P is associated with heart enlargement and apoptosis in murine dilated cardiomyopathy induced by Taenia crassiceps infection. J Parasitol 93, 1121-1127.
    • (2007) J Parasitol , vol.93 , pp. 1121-1127
    • D'Souza, M.1    Garza, M.A.2    Xie, M.3    Weinstock, J.4    Xiang, Q.5    Robinson, P.6
  • 25
    • 0029891149 scopus 로고    scopus 로고
    • Methods used to study immunoregulation of schistosome egg granulomas
    • Elliott, D. 1996. Methods used to study immunoregulation of schistosome egg granulomas. Immunomethods 9, 255-262.
    • (1996) Immunomethods , vol.9 , pp. 255-262
    • Elliott, D.1
  • 26
    • 0029786762 scopus 로고    scopus 로고
    • Granulomas in murine schistosomiasis mansoni have a somatostatin immunoregulatory circuit
    • Elliott, D.E. & Weinstock, J.V. 1996. Granulomas in murine schistosomiasis mansoni have a somatostatin immunoregulatory circuit. Metabolism 45(Suppl), 81-90.
    • (1996) Metabolism , vol.45 , pp. 81-90
    • Elliott, D.E.1    Weinstock, J.V.2
  • 27
    • 0032522418 scopus 로고    scopus 로고
    • Preprosomatostatin messenger RNA is expressed by inflammatory cells and induced by inflammatory mediators and cytokines
    • Elliott, D.E., Blum, A.M., Li, J., Metwali, A. & Weinstock, J.V. 1998. Preprosomatostatin messenger RNA is expressed by inflammatory cells and induced by inflammatory mediators and cytokines. J Immunol 160, 3997-4003.
    • (1998) J Immunol , vol.160 , pp. 3997-4003
    • Elliott, D.E.1    Blum, A.M.2    Li, J.3    Metwali, A.4    Weinstock, J.V.5
  • 28
    • 0037371261 scopus 로고    scopus 로고
    • Reduced CTL response and increased viral burden in substance P receptor-deficient mice infected with murine gamma-herpesvirus 68
    • Elsawa, S.F., Taylor, W., Petty, C.C., Marriott, I., Weinstock, J.V. & Bost, K.L. 2003. Reduced CTL response and increased viral burden in substance P receptor-deficient mice infected with murine gamma-herpesvirus 68. J Immunol 170, 2605-2612.
    • (2003) J Immunol , vol.170 , pp. 2605-2612
    • Elsawa, S.F.1    Taylor, W.2    Petty, C.C.3    Marriott, I.4    Weinstock, J.V.5    Bost, K.L.6
  • 31
    • 44949152566 scopus 로고    scopus 로고
    • Substance P receptor antagonist reverses intestinal pathophysiological alterations occurring in a novel ex-vivo model of Cryptosporidium parvum infection of intestinal tissues derived from SIV-infected macaques
    • Garza, A., Lackner, A., Aye, P., D'Souza, M., Martin, P. Jr, Borda, J., Tweardy, D.J., Weinstock, J., Griffiths, J. & Robinson, P. 2008. Substance P receptor antagonist reverses intestinal pathophysiological alterations occurring in a novel ex-vivo model of Cryptosporidium parvum infection of intestinal tissues derived from SIV-infected macaques. J Med Primatol 37, 109-115.
    • (2008) J Med Primatol , vol.37 , pp. 109-115
    • Garza, A.1    Lackner, A.2    Aye, P.3    D'Souza, M.4    Martin Jr., P.5    Borda, J.6    Tweardy, D.J.7    Weinstock, J.8    Griffiths, J.9    Robinson, P.10
  • 32
    • 77951920089 scopus 로고    scopus 로고
    • Substance P signaling contributes to granuloma formation in Taenia crassiceps infection, a murine model of cysticercosis
    • Garza, A., Tweardy, D.J., Weinstock, J., Viswanathan, B. & Robinson, P. 2010. Substance P signaling contributes to granuloma formation in Taenia crassiceps infection, a murine model of cysticercosis. J Biomed Biotechnol 2010, 597086.
    • (2010) J Biomed Biotechnol , vol.2010 , pp. 597086
    • Garza, A.1    Tweardy, D.J.2    Weinstock, J.3    Viswanathan, B.4    Robinson, P.5
  • 34
    • 0032167525 scopus 로고    scopus 로고
    • Substance P (neurokinin-1) receptor is a marker of human mucosal but not peripheral mononuclear cells: molecular quantitation and localization
    • Goode, T., O'Connell, J., Sternini, C., Anton, P., Wong, H., O'Sullivan, G.C., Collins, J.K. & Shanahan, F. 1998. Substance P (neurokinin-1) receptor is a marker of human mucosal but not peripheral mononuclear cells: molecular quantitation and localization. J Immunol 161, 2232-2240.
    • (1998) J Immunol , vol.161 , pp. 2232-2240
    • Goode, T.1    O'Connell, J.2    Sternini, C.3    Anton, P.4    Wong, H.5    O'Sullivan, G.C.6    Collins, J.K.7    Shanahan, F.8
  • 35
    • 0033855333 scopus 로고    scopus 로고
    • Neurokinin-1 receptor expression in inflammatory bowel disease: molecular quantitation and localisation
    • Goode, T., O'Connell, J., Anton, P., Wong, H., Reeve, J., O'Sullivan, G.C., Collins, J.K. & Shanahan, F. 2000a. Neurokinin-1 receptor expression in inflammatory bowel disease: molecular quantitation and localisation. Gut 47, 387-396.
    • (2000) Gut , vol.47 , pp. 387-396
    • Goode, T.1    O'Connell, J.2    Anton, P.3    Wong, H.4    Reeve, J.5    O'Sullivan, G.C.6    Collins, J.K.7    Shanahan, F.8
  • 37
    • 0036632174 scopus 로고    scopus 로고
    • Neutralizing anti-F glycoprotein and anti-substance P antibody treatment effectively reduces infection and inflammation associated with respiratory syncytial virus infection
    • Haynes, L.M., Tonkin, J., Anderson, L.J. & Tripp, R.A. 2002. Neutralizing anti-F glycoprotein and anti-substance P antibody treatment effectively reduces infection and inflammation associated with respiratory syncytial virus infection. J Virol 76, 6873-6881.
    • (2002) J Virol , vol.76 , pp. 6873-6881
    • Haynes, L.M.1    Tonkin, J.2    Anderson, L.J.3    Tripp, R.A.4
  • 38
    • 34548405221 scopus 로고    scopus 로고
    • Neurokinin-1 receptor antagonist treatment protects mice against lung injury in polymicrobial sepsis
    • Hegde, A., Zhang, H., Moochhala, S.M. & Bhatia, M. 2007. Neurokinin-1 receptor antagonist treatment protects mice against lung injury in polymicrobial sepsis. J Leukoc Biol 82, 678-685.
    • (2007) J Leukoc Biol , vol.82 , pp. 678-685
    • Hegde, A.1    Zhang, H.2    Moochhala, S.M.3    Bhatia, M.4
  • 39
    • 77951942383 scopus 로고    scopus 로고
    • Substance P in polymicrobial sepsis: molecular fingerprint of lung injury in preprotachykinin-A-/- mice
    • Hegde, A., Tamizhselvi, R., Manikandan, J., Melendez, A.J., Moochhala, S.M. & Bhatia, M. 2010. Substance P in polymicrobial sepsis: molecular fingerprint of lung injury in preprotachykinin-A-/- mice. Mol Med 16, 188-198.
    • (2010) Mol Med , vol.16 , pp. 188-198
    • Hegde, A.1    Tamizhselvi, R.2    Manikandan, J.3    Melendez, A.J.4    Moochhala, S.M.5    Bhatia, M.6
  • 40
    • 0030561086 scopus 로고    scopus 로고
    • Substance P augments interleukin-10 and tumor necrosis factor-alpha release by human cord blood monocytes and macrophages
    • Ho, W.Z., Kaufman, D., Uvaydova, M. & Douglas, S.D. 1996. Substance P augments interleukin-10 and tumor necrosis factor-alpha release by human cord blood monocytes and macrophages. J Neuroimmunol 71, 73-80.
    • (1996) J Neuroimmunol , vol.71 , pp. 73-80
    • Ho, W.Z.1    Kaufman, D.2    Uvaydova, M.3    Douglas, S.D.4
  • 41
    • 0031301905 scopus 로고    scopus 로고
    • Human monocytes and macrophages express substance P and neurokinin-1 receptor
    • Ho, W.Z., Lai, J.P., Zhu, X.H., Uvaydova, M. & Douglas, S.D. 1997. Human monocytes and macrophages express substance P and neurokinin-1 receptor. J Immunol 159, 5654-5660.
    • (1997) J Immunol , vol.159 , pp. 5654-5660
    • Ho, W.Z.1    Lai, J.P.2    Zhu, X.H.3    Uvaydova, M.4    Douglas, S.D.5
  • 42
    • 0036550698 scopus 로고    scopus 로고
    • HIV enhances substance P expression in human immune cells
    • Ho, W.Z., Lai, J.P., Li, Y. & Douglas, S.D. 2002. HIV enhances substance P expression in human immune cells. FASEB J 16, 616-618.
    • (2002) FASEB J , vol.16 , pp. 616-618
    • Ho, W.Z.1    Lai, J.P.2    Li, Y.3    Douglas, S.D.4
  • 43
    • 0027167752 scopus 로고
    • Downregulation of neutral endopeptidase (EC 3.4.24.11) in the inflamed rat intestine
    • Hwang, L., Leichter, R., Okamoto, A., Payan, D., Collins, S.M. & Bunnett, N.W. 1993. Downregulation of neutral endopeptidase (EC 3.4.24.11) in the inflamed rat intestine. Am J Physiol 264, 35-43.
    • (1993) Am J Physiol , vol.264 , pp. 35-43
    • Hwang, L.1    Leichter, R.2    Okamoto, A.3    Payan, D.4    Collins, S.M.5    Bunnett, N.W.6
  • 44
    • 0028543664 scopus 로고
    • Substance-P-mediated intestinal inflammation: inhibitory effects of CP 96,345 and SMS 201-995
    • Kataeva, G., Agro, A. & Stanisz, A.M. 1994. Substance-P-mediated intestinal inflammation: inhibitory effects of CP 96, 345 and SMS 201-995. Neuroimmunomodulation 1, 350-356.
    • (1994) Neuroimmunomodulation , vol.1 , pp. 350-356
    • Kataeva, G.1    Agro, A.2    Stanisz, A.M.3
  • 45
  • 46
    • 0029896011 scopus 로고    scopus 로고
    • Increased susceptibility of mice to Salmonella infection following in vivo treatment with the substance P antagonist, spantide II
    • Kincy-Cain, T. & Bost, K.L. 1996. Increased susceptibility of mice to Salmonella infection following in vivo treatment with the substance P antagonist, spantide II. J Immunol 157, 255-264.
    • (1996) J Immunol , vol.157 , pp. 255-264
    • Kincy-Cain, T.1    Bost, K.L.2
  • 47
    • 0031092708 scopus 로고    scopus 로고
    • Substance P-induced IL-12 production by murine macrophages
    • Kincy-Cain, T. & Bost, K.L. 1997. Substance P-induced IL-12 production by murine macrophages. J Immunol 158, 2334-2339.
    • (1997) J Immunol , vol.158 , pp. 2334-2339
    • Kincy-Cain, T.1    Bost, K.L.2
  • 48
    • 0032100709 scopus 로고    scopus 로고
    • Human lymphocytes express substance P and its receptor
    • Lai, J.P., Douglas, S.D. & Ho, W.Z. 1998. Human lymphocytes express substance P and its receptor. J Neuroimmunol 86, 80-86.
    • (1998) J Neuroimmunol , vol.86 , pp. 80-86
    • Lai, J.P.1    Douglas, S.D.2    Ho, W.Z.3
  • 49
    • 0035957351 scopus 로고    scopus 로고
    • Substance P antagonist (CP-96,345) inhibits HIV-1 replication in human mononuclear phagocytes
    • Lai, J.P., Ho, W.Z., Zhan, G.X., Yi, Y., Collman, R.G. & Douglas, S.D. 2001. Substance P antagonist (CP-96, 345) inhibits HIV-1 replication in human mononuclear phagocytes. Proc Natl Acad Sci USA 98, 3970-3975.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3970-3975
    • Lai, J.P.1    Ho, W.Z.2    Zhan, G.X.3    Yi, Y.4    Collman, R.G.5    Douglas, S.D.6
  • 51
    • 0032514760 scopus 로고    scopus 로고
    • Neuropeptides, by direct interaction with T cells, induce cytokine secretion and break the commitment to a distinct T helper phenotype
    • Levite, M. 1998. Neuropeptides, by direct interaction with T cells, induce cytokine secretion and break the commitment to a distinct T helper phenotype. Proc Natl Acad Sci USA 95, 12544-12549.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 12544-12549
    • Levite, M.1
  • 52
    • 0034600069 scopus 로고    scopus 로고
    • Extracellular K(+) and opening of voltage-gated potassium channels activate T cell integrin function: physical and functional association between Kv1.3 channels and beta1 integrins
    • Levite, M., Cahalon, L., Peretz, A., Hershkoviz, R., Sobko, A., Ariel, A., Desai, R., Attali, B. & Lider, O. 2000. Extracellular K(+) and opening of voltage-gated potassium channels activate T cell integrin function: physical and functional association between Kv1.3 channels and beta1 integrins. J Exp Med 191, 1167-1176.
    • (2000) J Exp Med , vol.191 , pp. 1167-1176
    • Levite, M.1    Cahalon, L.2    Peretz, A.3    Hershkoviz, R.4    Sobko, A.5    Ariel, A.6    Desai, R.7    Attali, B.8    Lider, O.9
  • 53
    • 18844422695 scopus 로고    scopus 로고
    • Substance P regulates natural killer cell interferon-gamma production and resistance to Pseudomonas aeruginosa infection
    • Lighvani, S., Huang, X., Trivedi, P.P., Swanborg, R.H. & Hazlett, L.D. 2005. Substance P regulates natural killer cell interferon-gamma production and resistance to Pseudomonas aeruginosa infection. Eur J Immunol 35, 1567-1575.
    • (2005) Eur J Immunol , vol.35 , pp. 1567-1575
    • Lighvani, S.1    Huang, X.2    Trivedi, P.P.3    Swanborg, R.H.4    Hazlett, L.D.5
  • 54
    • 0005061019 scopus 로고
    • Receptor binding sites for substance P, but not substance K or neuromedin K, are expressed in high concentrations by arterioles, venules, and lymph nodules in surgical specimens obtained from patients with ulcerative colitis and Crohn disease
    • Mantyh, C.R., Gates, T.S., Zimmerman, R.P., Welton, M.L., Passaro, E.P. Jr, Vigna, S.R., Maggio, J.E., Kruger, L. & Mantyh, P.W. 1988. Receptor binding sites for substance P, but not substance K or neuromedin K, are expressed in high concentrations by arterioles, venules, and lymph nodules in surgical specimens obtained from patients with ulcerative colitis and Crohn disease. Proc Natl Acad Sci USA 85, 3235-3239.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 3235-3239
    • Mantyh, C.R.1    Gates, T.S.2    Zimmerman, R.P.3    Welton, M.L.4    Passaro Jr., E.P.5    Vigna, S.R.6    Maggio, J.E.7    Kruger, L.8    Mantyh, P.W.9
  • 55
    • 0032007163 scopus 로고    scopus 로고
    • Substance P diminishes lipopolysaccharide and interferon-gamma-induced TGF-beta 1 production by cultured murine macrophages
    • Marriott, I. & Bost, K.L. 1998. Substance P diminishes lipopolysaccharide and interferon-gamma-induced TGF-beta 1 production by cultured murine macrophages. Cell Immunol 183, 113-120.
    • (1998) Cell Immunol , vol.183 , pp. 113-120
    • Marriott, I.1    Bost, K.L.2
  • 56
    • 0034235803 scopus 로고    scopus 로고
    • IL-4 and IFN-gamma up-regulate substance P receptor expression in murine peritoneal macrophages
    • Marriott, I. & Bost, K.L. 2000. IL-4 and IFN-gamma up-regulate substance P receptor expression in murine peritoneal macrophages. J Immunol 165, 182-191.
    • (2000) J Immunol , vol.165 , pp. 182-191
    • Marriott, I.1    Bost, K.L.2
  • 57
    • 84885871465 scopus 로고    scopus 로고
    • Neuropeptide SP activates the WNT signal transduction pathway and enhances the proliferation of bone marrow stromal stem cells
    • Mei, G., Xia, L., Zhou, J., Zhang, Y., Tuo, Y., Fu, S., Zou, Z., Wang, Z. & Jin, D. 2013. Neuropeptide SP activates the WNT signal transduction pathway and enhances the proliferation of bone marrow stromal stem cells. Cell Biol Int 37, 1225-1232.
    • (2013) Cell Biol Int , vol.37 , pp. 1225-1232
    • Mei, G.1    Xia, L.2    Zhou, J.3    Zhang, Y.4    Tuo, Y.5    Fu, S.6    Zou, Z.7    Wang, Z.8    Jin, D.9
  • 58
    • 0035203076 scopus 로고    scopus 로고
    • Hemokinin 1 is a full agonist at the substance P receptor
    • Comment Letter.
    • Morteau, O., Lu, B., Gerard, C. & Gerard, N.P. 2001. Hemokinin 1 is a full agonist at the substance P receptor. Nat Immunol 2, 1088 (Comment Letter).
    • (2001) Nat Immunol , vol.2 , pp. 1088
    • Morteau, O.1    Lu, B.2    Gerard, C.3    Gerard, N.P.4
  • 59
    • 30944433368 scopus 로고    scopus 로고
    • Quantification of hemokinin-1 peptide production and secretion from mouse B cells
    • Nelson, D.A. & Bost, K.L. 2005. Quantification of hemokinin-1 peptide production and secretion from mouse B cells. Cell Immunol 237, 115-122.
    • (2005) Cell Immunol , vol.237 , pp. 115-122
    • Nelson, D.A.1    Bost, K.L.2
  • 60
    • 0028861975 scopus 로고
    • Antibodies to interleukin 12 abrogate established experimental colitis in mice
    • Neurath, M.F., Fuss, I., Kelsall, B.L., Stuber, E. & Strober, W. 1995. Antibodies to interleukin 12 abrogate established experimental colitis in mice. J Exp Med 182, 1281-1290.
    • (1995) J Exp Med , vol.182 , pp. 1281-1290
    • Neurath, M.F.1    Fuss, I.2    Kelsall, B.L.3    Stuber, E.4    Strober, W.5
  • 61
    • 38949194905 scopus 로고    scopus 로고
    • Role of preprotachykinin-A gene products on multiple organ injury in LPS-induced endotoxemia
    • Ng, S.W., Zhang, H., Hegde, A. & Bhatia, M. 2008. Role of preprotachykinin-A gene products on multiple organ injury in LPS-induced endotoxemia. J Leukoc Biol 83, 288-295.
    • (2008) J Leukoc Biol , vol.83 , pp. 288-295
    • Ng, S.W.1    Zhang, H.2    Hegde, A.3    Bhatia, M.4
  • 62
    • 0028354003 scopus 로고
    • Interactions between neutral endopeptidase (EC 3.4.24.11) and the substance P (NK1) receptor expressed in mammalian cells
    • Okamoto, A., Lovett, M., Payan, D.G. & Bunnett, N.W. 1994. Interactions between neutral endopeptidase (EC 3.4.24.11) and the substance P (NK1) receptor expressed in mammalian cells. Biochem J 299, 683-693.
    • (1994) Biochem J , vol.299 , pp. 683-693
    • Okamoto, A.1    Lovett, M.2    Payan, D.G.3    Bunnett, N.W.4
  • 63
    • 79251551395 scopus 로고    scopus 로고
    • Substance P is a key mediator of stress-induced protection from allergic sensitization via modified antigen presentation
    • Pavlovic, S., Liezmann, C., Blois, S.M., Joachim, R., Kruse, J., Romani, N., Klapp, B.F. & Peters, E.M. 2011. Substance P is a key mediator of stress-induced protection from allergic sensitization via modified antigen presentation. J Immunol 186, 848-855.
    • (2011) J Immunol , vol.186 , pp. 848-855
    • Pavlovic, S.1    Liezmann, C.2    Blois, S.M.3    Joachim, R.4    Kruse, J.5    Romani, N.6    Klapp, B.F.7    Peters, E.M.8
  • 64
    • 0032758458 scopus 로고    scopus 로고
    • Respiratory syncytial virus upregulates expression of the substance P receptor in rat lungs
    • Piedimonte, G., Rodriguez, M.M., King, K.A., McLean, S. & Jiang, X. 1999. Respiratory syncytial virus upregulates expression of the substance P receptor in rat lungs. Am J Physiol 277, L831-L840.
    • (1999) Am J Physiol , vol.277 , pp. L831-L840
    • Piedimonte, G.1    Rodriguez, M.M.2    King, K.A.3    McLean, S.4    Jiang, X.5
  • 65
  • 66
    • 33644845136 scopus 로고    scopus 로고
    • Preprotachykinin-A gene products are key mediators of lung injury in polymicrobial sepsis
    • Puneet, P., Hegde, A., Ng, S.W., Lau, H.Y., Lu, J., Moochhala, S.M. & Bhatia, M. 2006. Preprotachykinin-A gene products are key mediators of lung injury in polymicrobial sepsis. J Immunol 176, 3813-3820.
    • (2006) J Immunol , vol.176 , pp. 3813-3820
    • Puneet, P.1    Hegde, A.2    Ng, S.W.3    Lau, H.Y.4    Lu, J.5    Moochhala, S.M.6    Bhatia, M.7
  • 68
    • 0034955149 scopus 로고    scopus 로고
    • Both substance P and its receptor are expressed in mouse intestinal T lymphocytes
    • Qian, B.F., Zhou, G.Q., Hammarstrom, M.L. & Danielsson, A. 2001. Both substance P and its receptor are expressed in mouse intestinal T lymphocytes. Neuroendocrinology 73, 358-368.
    • (2001) Neuroendocrinology , vol.73 , pp. 358-368
    • Qian, B.F.1    Zhou, G.Q.2    Hammarstrom, M.L.3    Danielsson, A.4
  • 69
    • 78650763993 scopus 로고    scopus 로고
    • Altered host response to murine gammaherpesvirus 68 infection in mice lacking the tachykinin 1 gene and the receptor for substance P
    • Quinn, J.P., Kipar, A., Hughes, D.J., Bennett, E., Cox, H., McLaughlin, L., Zimmer, A., Hunt, S.P. & Stewart, J.P. 2011. Altered host response to murine gammaherpesvirus 68 infection in mice lacking the tachykinin 1 gene and the receptor for substance P. Neuropeptides 45, 49-53.
    • (2011) Neuropeptides , vol.45 , pp. 49-53
    • Quinn, J.P.1    Kipar, A.2    Hughes, D.J.3    Bennett, E.4    Cox, H.5    McLaughlin, L.6    Zimmer, A.7    Hunt, S.P.8    Stewart, J.P.9
  • 70
    • 0032524989 scopus 로고    scopus 로고
    • Localization and regulation of IFN-gamma production within the granulomas of murine schistosomiasis in IL-4-deficient and control mice
    • Rakasz, E., Blum, A.M., Metwali, A., Elliott, D.E., Li, J., Ballas, Z.K., Qadir, K., Lynch, R. & Weinstock, J.V. 1998. Localization and regulation of IFN-gamma production within the granulomas of murine schistosomiasis in IL-4-deficient and control mice. J Immunol 160, 4994-4999.
    • (1998) J Immunol , vol.160 , pp. 4994-4999
    • Rakasz, E.1    Blum, A.M.2    Metwali, A.3    Elliott, D.E.4    Li, J.5    Ballas, Z.K.6    Qadir, K.7    Lynch, R.8    Weinstock, J.V.9
  • 71
    • 2142810261 scopus 로고    scopus 로고
    • Substance P augments Borrelia burgdorferi-induced prostaglandin E2 production by murine microglia
    • Rasley, A., Marriott, I., Halberstadt, C.R., Bost, K.L. & Anguita, J. 2004. Substance P augments Borrelia burgdorferi-induced prostaglandin E2 production by murine microglia. J Immunol 172, 5707-5713.
    • (2004) J Immunol , vol.172 , pp. 5707-5713
    • Rasley, A.1    Marriott, I.2    Halberstadt, C.R.3    Bost, K.L.4    Anguita, J.5
  • 73
    • 54349120228 scopus 로고    scopus 로고
    • Substance P receptor antagonism for treatment of cryptosporidiosis in immunosuppressed mice
    • Robinson, P., Martin, P. Jr, Garza, A., D'Souza, M., Mastrangelo, M.A. & Tweardy, D. 2008. Substance P receptor antagonism for treatment of cryptosporidiosis in immunosuppressed mice. J Parasitol 94, 1150-1154.
    • (2008) J Parasitol , vol.94 , pp. 1150-1154
    • Robinson, P.1    Martin Jr., P.2    Garza, A.3    D'Souza, M.4    Mastrangelo, M.A.5    Tweardy, D.6
  • 74
    • 84863418962 scopus 로고    scopus 로고
    • Hemokinin-1 gene expression is upregulated in microglia activated by lipopolysaccharide through NF-B and p38 MAPK signaling pathways
    • [Electronic Resource]
    • Sakai, A., Takasu, K., Sawada, M. & Suzuki, H. 2012. Hemokinin-1 gene expression is upregulated in microglia activated by lipopolysaccharide through NF-B and p38 MAPK signaling pathways. PLoS ONE [Electronic Resource] 7, e32268.
    • (2012) PLoS ONE , vol.7 , pp. e32268
    • Sakai, A.1    Takasu, K.2    Sawada, M.3    Suzuki, H.4
  • 75
    • 0032412057 scopus 로고    scopus 로고
    • Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
    • Sellon, R.K., Tonkonogy, S., Schultz, M., Dieleman, L.A., Grenther, W., Balish, E., Rennick, D.M. & Sartor, R.B. 1998. Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect Immun 66, 5224-5231.
    • (1998) Infect Immun , vol.66 , pp. 5224-5231
    • Sellon, R.K.1    Tonkonogy, S.2    Schultz, M.3    Dieleman, L.A.4    Grenther, W.5    Balish, E.6    Rennick, D.M.7    Sartor, R.B.8
  • 77
    • 0032575543 scopus 로고    scopus 로고
    • Localization of the neurokinin 1 (NK-1) receptor in the human antrum and duodenum
    • Smith, V.C., Sagot, M.A., Couraud, J.Y. & Buchan, A.M. 1998. Localization of the neurokinin 1 (NK-1) receptor in the human antrum and duodenum. Neurosci Lett 253, 49-52.
    • (1998) Neurosci Lett , vol.253 , pp. 49-52
    • Smith, V.C.1    Sagot, M.A.2    Couraud, J.Y.3    Buchan, A.M.4
  • 78
    • 45849144078 scopus 로고    scopus 로고
    • Induction of tachykinin production in airway epithelia in response to viral infection
    • [Electronic Resource]
    • Stewart, J.P., Kipar, A., Cox, H., Payne, C., Vasiliou, S. & Quinn, J.P. 2008. Induction of tachykinin production in airway epithelia in response to viral infection. PLoS ONE [Electronic Resource] 3, e1673.
    • (2008) PLoS ONE , vol.3 , pp. e1673
    • Stewart, J.P.1    Kipar, A.2    Cox, H.3    Payne, C.4    Vasiliou, S.5    Quinn, J.P.6
  • 80
    • 0036347641 scopus 로고    scopus 로고
    • Substance P receptor expression on lymphocytes is associated with the immune response to respiratory syncytial virus infection
    • Tripp, R.A., Barskey, A., Goss, L. & Anderson, L.J. 2002. Substance P receptor expression on lymphocytes is associated with the immune response to respiratory syncytial virus infection. J Neuroimmunol 129, 141-153.
    • (2002) J Neuroimmunol , vol.129 , pp. 141-153
    • Tripp, R.A.1    Barskey, A.2    Goss, L.3    Anderson, L.J.4
  • 82
    • 0025819419 scopus 로고
    • Alterations of the intestinal innervation in mice infected with Schistosoma mansoni
    • Varilek, G.W., Weinstock, J.V., Williams, T.H. & Jew, J. 1991. Alterations of the intestinal innervation in mice infected with Schistosoma mansoni. J Parasitol 77, 472-478.
    • (1991) J Parasitol , vol.77 , pp. 472-478
    • Varilek, G.W.1    Weinstock, J.V.2    Williams, T.H.3    Jew, J.4
  • 83
    • 0024550476 scopus 로고
    • Tachykinin production in granulomas of murine schistosomiasis mansoni
    • Weinstock, J.V. & Blum, A.M. 1989. Tachykinin production in granulomas of murine schistosomiasis mansoni. J Immunol 142, 3256-3261.
    • (1989) J Immunol , vol.142 , pp. 3256-3261
    • Weinstock, J.V.1    Blum, A.M.2
  • 84
    • 0023688665 scopus 로고
    • Eosinophils from granulomas in murine schistosomiasis mansoni produce substance P
    • Weinstock, J.V., Blum, A., Walder, J. & Walder, R. 1988. Eosinophils from granulomas in murine schistosomiasis mansoni produce substance P. J Immunol 141, 961-966.
    • (1988) J Immunol , vol.141 , pp. 961-966
    • Weinstock, J.V.1    Blum, A.2    Walder, J.3    Walder, R.4
  • 85
    • 0025604699 scopus 로고
    • Macrophages within the granulomas of murine Schistosoma mansoni are a source of a somatostatin 1-14-like molecule
    • Weinstock, J.V., Blum, A.M. & Malloy, T. 1990. Macrophages within the granulomas of murine Schistosoma mansoni are a source of a somatostatin 1-14-like molecule. Cell Immunol 131, 381-390.
    • (1990) Cell Immunol , vol.131 , pp. 381-390
    • Weinstock, J.V.1    Blum, A.M.2    Malloy, T.3
  • 86
    • 0038665250 scopus 로고    scopus 로고
    • IL-18 and IL-12 signal through the NF-kappa B pathway to induce NK-1R expression on T cells
    • Weinstock, J.V., Blum, A., Metwali, A., Elliott, D. & Arsenescu, R. 2003a. IL-18 and IL-12 signal through the NF-kappa B pathway to induce NK-1R expression on T cells. J Immunol 170, 5003-5007.
    • (2003) J Immunol , vol.170 , pp. 5003-5007
    • Weinstock, J.V.1    Blum, A.2    Metwali, A.3    Elliott, D.4    Arsenescu, R.5
  • 88
    • 0034332431 scopus 로고    scopus 로고
    • Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis
    • Zhang, Y., Lu, L., Furlonger, C., Wu, G.E. & Paige, C.J. 2000. Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis. Nat Immunol 1, 392-397.
    • (2000) Nat Immunol , vol.1 , pp. 392-397
    • Zhang, Y.1    Lu, L.2    Furlonger, C.3    Wu, G.E.4    Paige, C.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.