Altered host response to murine gammaherpesvirus 68 infection in mice lacking the tachykinin 1 gene and the receptor for substance P

Neuropeptides

Volumn 45, Issue 1, 2011, Pages 49-53

  Quinn, John P ^a   Kipar, Anja ^a   Hughes, David J ^a   Bennett, Elaine ^a   Cox, Helen ^a   McLaughlin, Lynn ^a   Zimmer, Andreas ^b   Hunt, Stephen P ^c   Stewart, James P ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b UNIVERSITY OF BONN   (Germany)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

NK1; Substance P; Tachykinin; Transgenic mice; Virus

Indexed keywords

SUBSTANCE P; TACHYKININ RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; GAMMAHERPESVIRINAE; HERPES VIRUS INFECTION; HISTOPATHOLOGY; IMMUNE RESPONSE; INFECTION SENSITIVITY; KNOCKOUT MOUSE; LUNG; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TRANSGENIC MOUSE; WILD TYPE;

ANIMALS; HERPESVIRIDAE INFECTIONS; HOST-PATHOGEN INTERACTIONS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, NEUROKININ-1; RHADINOVIRUS; SUBSTANCE P; TACHYKININS; TUMOR VIRUS INFECTIONS;

ANIMALIA; MURINAE; MUS; MUS MUSCULUS;

EID: 78650763993     PISSN: 01434179     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.npep.2010.10.004     Document Type: Article

References (42)

1. Blaskovic D., Stancekova M., Svobodova J., Mistrikova J. Isolation of five strains of herpesviruses from two species of free living small rodents. Acta Virol. 1980, 24:468.
2. Bowden R.J., Simas J.P., Davis A.J., Efstathiou S. Murine gammaherpesvirus 68 encodes tRNA-like sequences which are expressed during latency. J. Gen. Virol. 1997, 78:1675-1687.
3. D'Agostino B., Advenier C., de Palma R., Gallelli L., Marrocco G., Abbate G.F., Rossi F. The involvement of sensory neuropeptides in airway hyper-responsiveness in rabbits sensitized and challenged to Parietaria judaica. Clin. Exp. Allergy 2002, 32:472-479.
4. Dakhama A., Park J.W., Taube C., El Gazzar M., Kodama T., Miyahara N., Takeda K., Kanehiro A., Balhorn A., Joetham A., Loader J.E., Larsen G.L., Gelfand E.W. Alteration of airway neuropeptide expression and development of airway hyperresponsiveness following respiratory syncytial virus infection. Am. J. Physiol. Lung Cell. Mol. Physiol. 2005, 288:L761-L770.
5. De Felipe C., Herrero J.F., O'Brien J.A., Palmer J.A., Doyle C.A., Smith A.J., Laird J.M., Belmonte C., Cervero F., Hunt S.P. Altered nociception, analgesia and aggression in mice lacking the receptor for substance P. Nature 1998, 392:394-397.
6. Efstathiou S., Ho Y.M., Minson A.C. Cloning and molecular characterization of the murine herpesvirus 68 genome. J. Gen. Virol. 1990, 71:1355-1364.
7. Elsawa S.F., Taylor W., Petty C.C., Marriott I., Weinstock J.V., Bost K.L. Reduced CTL response and increased viral burden in substance P receptor-deficient mice infected with murine gamma-herpesvirus 68. J. Immunol. 2003, 170:2605-2612.
8. Germonpre P.R., Bullock G.R., Lambrecht B.N., Van De Velde V., Luyten W.H., Joos G.F., Pauwels R.A. Presence of substance P and neurokinin 1 receptors in human sputum macrophages and U-937 cells. Eur. Respir. J. 1999, 14:776-782.
9. Goetzl E.J., Sreedharan S.P. Mediators of communication and adaptation in the neuroendocrine and immune systems. FASEB J. 1992, 6:2646-2652.
10. Haynes L.M., Tonkin J., Anderson L.J., Tripp R.A. Neutralizing anti-F glycoprotein and anti-substance P antibody treatment effectively reduces infection and inflammation associated with respiratory syncytial virus infection. J. Virol. 2002, 76:6873-6881.
11. Hegde A., Zhang H., Moochhala S.M., Bhatia M. Neurokinin-1 receptor antagonist treatment protects mice against lung injury in polymicrobial sepsis. J. Leukoc. Biol. 2007, 82:678-685.
12. Ho W.Z., Lai J.P., Zhu X.H., Uvaydova M., Douglas S.D. Human monocytes and macrophages express substance P and neurokinin-1 receptor. J. Immunol. 1997, 159:5654-5660.
13. Hughes D.J., Kipar A., Milligan S.G., Cunningham C., Sanders M., Quail M.A., Rajandream M.A., Efstathiou S., Bowden R.J., Chastel C., Bennett M., Sample J.T., Barrell B., Davison A.J., Stewart J.P. Characterization of a novel wood mouse virus related to murid herpesvirus 4. J. Gen. Virol. 2010, 91:867-879.
14. Joos G.F., Germonpre P.R., Pauwels R.A. Role of tachykinins in asthma. Allergy 2000, 55:321-337.
15. Kamijo Y., Hayashi I., Soma K., Ohwada T., Majima M. Effect of neutral endopeptidase inhibitor on bradykinin-induced bronchoconstriction. Life Sci. 2001, 70:1-15.
16. Kipar A., Kohler K., Leukert W., Reinacher M. A comparison of lymphatic tissues from cats with spontaneous feline infectious peritonitis (FIP), cats with FIP virus infection but no FIP, and cats with no infection. J. Comp. Pathol. 2001, 125:182-191.
17. Lai J.P., Douglas S.D., Ho W.Z. Human lymphocytes express substance P and its receptor. J. Neuroimmunol. 1998, 86:80-86.
18. Lambrecht B.N., Germonpre P.R., Everaert E.G., Carro-Muino I., De Veerman M., de Felipe C., Hunt S.P., Thielemans K., Joos G.F., Pauwels R.A. Endogenously produced substance P contributes to lymphocyte proliferation induced by dendritic cells and direct TCR ligation. Eur. J. Immunol. 1999, 29:3815-3825.
19. Lotz M., Vaughan J.H., Carson D.A. Effect of neuropeptides on production of inflammatory cytokines by human monocytes. Science 1988, 241:1218-1221.
20. MacKenzie A., Payne C., Boyle S., Clarke A.R., Quinn J.P. The human preprotachykinin-A gene promoter has been highly conserved and can drive human-like marker gene expression in the adult mouse CNS. Mol. Cell. Neurosci. 2000, 16:620-630.
21. MacKenzie A., Quinn J. A yeast artificial chromosome containing the human preprotachykinin-A gene expresses substance P in mice and drives appropriate marker-gene expression during early brain embryogenesis. Mol. Cell. Neurosci. 2002, 19:72-87.
22. Maggi C.A. The effects of tachykinins on inflammatory and immune cells. Regul. Pept. 1997, 70:75-90.
23. McGregor G.P., Hartel R., Haberberger R., Kummer W., Voigt K. Preprotachykinin-A gene expression occurs transiently in the developing rat endocrine pancreas and can be regulated in RINm5F cells. Endocrinology 1995, 136:2538-2546.
24. Morteau O., Lu B., Gerard C., Gerard N.P. Hemokinin 1 is a full agonist at the substance P receptor. Nat. Immunol. 2001, 2:1088.
25. Moyron-Quiroz J.E., Rangel-Moreno J., Kusser K., Hartson L., Sprague F., Goodrich S., Woodland D.L., Lund F.E., Randall T.D. Role of inducible bronchus associated lymphoid tissue (iBALT) in respiratory immunity. Nat. Med. 2004, 10:927-934.
26. Ng S.W., Zhang H., Hegde A., Bhatia M. Role of preprotachykinin-A gene products on multiple organ injury in LPS-induced endotoxemia. J. Leukoc. Biol. 2008, 83:288-295.
27. Noveral J.P., Grunstein M.M. Tachykinin regulation of airway smooth muscle cell proliferation. Am. J. Physiol. Lung Cell. Mol. Physiol. 1995, 269:L339-L343.
28. Palma C., Manzini S. Substance P induces secretion of immunomodulatory cytokines by human astrocytoma cells. J. Neuroimmunol. 1998, 81:127-137.
29. Payne C.M., Heggie C.J., Brownstein D.G., Stewart J.P., Quinn J.P. Role of tachykinins in the host response to murine gammaherpesvirus infection. J. Virol. 2001, 75:10467-10471.
30. Piedimonte G. Contribution of neuroimmune mechanisms to airway inflammation and remodeling during and after respiratory syncytial virus infection. Pediatr. Infect. Dis. J. 2003, 22:S66-S74. discussion S74-S65.
31. Piedimonte G., Rodriguez M.M., King K.A., McLean S., Jiang X. Respiratory syncytial virus upregulates expression of the substance P receptor in rat lungs. Am. J. Physiol. 1999, 277:L831-L840.
32. Puneet P., Hegde A., Ng S.W., Lau H.Y., Lu J., Moochhala S.M., Bhatia M. Preprotachykinin-A gene products are key mediators of lung injury in polymicrobial sepsis. J. Immunol. 2006, 176:3813-3820.
33. Singh D., Joshi D.D., Hameed M., Qian J., Gascon P., Maloof P.B., Mosenthal A., Rameshwar P. Increased expression of preprotachykinin-I and neurokinin receptors in human breast cancer cells: implications for bone marrow metastasis. Proc. Natl. Acad. Sci. USA 2000, 97:388-393.
34. Stewart J.P., Kipar A., Cox H., Payne C., Vasiliou S., Quinn J.P. Induction of tachykinin production in airway epithelia in response to viral infection. PLoS ONE 2008, 3:e1673.
35. Sunil-Chandra N.P., Efstathiou S., Arno J., Nash A.A. Virological and pathological features of mice infected with murine gamma-herpesvirus 68. J. Gen. Virol. 1992, 73:2347-2356.
36. Svensson A., Kaim J., Mallard C., Olsson A., Brodin E., Hokfelt T., Eriksson K. Neurokinin 1 receptor signaling affects the local innate immune defense against genital herpes virus infection. J. Immunol. 2005, 175:6802-6811.
37. Tripp R.A., Barskey A., Goss L., Anderson L.J. Substance P receptor expression on lymphocytes is associated with the immune response to respiratory syncytial virus infection. J. Neuroimmunol. 2002, 129:141-153.
38. Tripp R.A., Moore D., Winter J., Anderson L.J. Respiratory syncytial virus infection and G and/or SH protein expression contribute to substance P, which mediates inflammation and enhanced pulmonary disease in BALB/c mice. J. Virol. 2000, 74:1614-1622.
39. Zhang H., Hegde A., Ng S.W., Adhikari S., Moochhala S.M., Bhatia M. Hydrogen sulfide up-regulates substance P in polymicrobial sepsis-associated lung injury. J. Immunol. 2007, 179:4153-4160.
40. Zhang Y., Lu L., Furlonger C., Wu G.E., Paige C.J. Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis. Nat. Immunol. 2000, 1:392-397.
41. Zhang Y., Paige C.J. T-cell developmental blockage by tachykinin antagonists and the role of hemokinin 1 in T lymphopoiesis. Blood 2003, 102:2165-2172.
42. Zimmer A., Zimmer A.M., Baffi J., Usdin T., Reynolds K., Konig M., Palkovits M., Mezey E. Hypoalgesia in mice with a targeted deletion of the tachykinin 1 gene. Proc. Natl. Acad. Sci. USA 1998, 95:2630-2635.