Prophylactic and therapeutic targeting of the neurokinin-1 receptor limits neuroinflammation in a murine model of pneumococcal meningitis

Journal of Immunology

Volumn 186, Issue 12, 2011, Pages 7255-7263

  Chauhan, Vinita S ^a   Kluttz, John M ^a   Bost, Kenneth L ^a   Marriott, Ian ^a  

^a UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 BENZHYDRYL 3 (2 IODOBENZYLAMINO)QUINUCLIDINE; INTERLEUKIN 10; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUROKININ 1 RECEPTOR; SUBSTANCE P; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL LOAD; BRAIN HOMOGENATE; BRAIN LEVEL; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEMYELINATION; DRUG MECHANISM; DRUG TARGETING; GLIA CELL; GLIOSIS; MOUSE; NERVOUS SYSTEM INFLAMMATION; NEWBORN; NONHUMAN; PNEUMOCOCCAL MENINGITIS; PRIORITY JOURNAL; PROPHYLAXIS; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; STREPTOCOCCUS PNEUMONIAE;

ANIMALS; CENTRAL NERVOUS SYSTEM; CYTOKINES; DEMYELINATING DISEASES; GRAM-NEGATIVE BACTERIA; INFLAMMATION; MENINGITIS, PNEUMOCOCCAL; MICE; RECEPTORS, NEUROKININ-1;

EID: 79959563961     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1100721     Document Type: Article

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